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Kirtaner & Spardot's 420chan Wedding

To all guests, live viewers, and our Internet family, THANK YOU.
VODs will be edited soon, we are all so tired.
Wedding Gifts
Xanax + Nicotine from Vaping by Jenny Blankinseck - Sat, 02 Jun 2018 21:21:47 EST ID:35BpLStE No.141659 Ignore Report Quick Reply
File: 1527988907195.jpg -(402981B / 393.54KB, 900x1087) Thumbnail displayed, click image for full size. 402981
Bad or good or doesn't matter?
Dr. Katz !KqgSR25gAQ - Sat, 02 Jun 2018 22:51:21 EST ID:iTT7NEEz No.141660 Ignore Report Quick Reply
Nicotine will diminish to the effects of benzodiazepines, but it is rather common for people who recreationally take benzos to also smoke while benz’d.

Diminished effects

If you’re too benz’d you might enjoy the stimulation

Yup. Some people find that the effects are negligible though.
TinyTrip !5pb17tfZto - Sun, 03 Jun 2018 12:57:17 EST ID:ZWh/opqj No.141664 Ignore Report Quick Reply
+10 response

I can't even add shit is how good this response is. Lot of people don't realize the nicotine/benz interaction

Nb as not contributing but this is about as good of info youll get on a chan
Phineas Findergold - Sun, 03 Jun 2018 16:04:29 EST ID:INnlSvg6 No.141667 Ignore Report Quick Reply

Wait, is there actually a biological mechanism that reduces effects of benzodiazepines with nicotine intake? Or does it just sober you up cause it is stimmy and helps focus
TinyTrip !5pb17tfZto - Sun, 03 Jun 2018 16:36:49 EST ID:ZWh/opqj No.141668 Ignore Report Quick Reply
Pharmacokinetic, but yes. A lot of interactions fall a long ye old CYP trail. Less sedation found in smokers, can impact a variety medications.
Edward Pennerwut - Sun, 03 Jun 2018 21:50:07 EST ID:INnlSvg6 No.141675 Ignore Report Quick Reply
Good to keep in mind next time I benz, thanks!

I'm guilty of overvaping e-cigs while benzing, I can blow out massive clouds and it doesn't seem to make me panic or light headed
High Strung - Mon, 04 Jun 2018 10:32:09 EST ID:jkHAYtZi No.141683 Ignore Report Quick Reply
Last night I was at a party and I bummed a few smoked off some homies while I was benzed out on Clonazepam. It diminished the benz feelings a bit, but not by terribly much and once I smoked a little bud the benz feeling came back.
Dr. Katz !KqgSR25gAQ - Wed, 06 Jun 2018 13:57:10 EST ID:VDSB+A7H No.141716 Ignore Report Quick Reply
Thanks, Tiny!
People seem to forget the interaction or write it off as a falsehood.

TinyTrip !5pb17tfZto - Sat, 09 Jun 2018 12:52:40 EST ID:ZWh/opqj No.141759 Ignore Report Quick Reply
Np I learnt that one when I was young from an individual that kindled my interest in the subject.

I'm guilty of the same. Since sleep has been a pretty core issue of my illness I decided to test the difference in degree of sedation and after documenting it many times i can say the difference exists but its negligible (upon myself)

Yeah I was less sedated but in all honesty the "trials" where I abstained from nicotene interupted my sleep despite minor increases in those "comfy feels"

I did thise around age 18 so its pretty anecdotal and I was probably a stuck up kid at the time so YMMV
Dr. Katz !KqgSR25gAQ - Wed, 13 Jun 2018 15:06:21 EST ID:qExK9ErE No.141810 Ignore Report Quick Reply
I’m not a smoker, but everyone that I know who smokes and takes benzos will chain smoke on benzos. They don’t seem to care either way.
Anytime that I have smoked, which is rare, I didn’t personally notice a significant decrease in sedation. That would have been around ages 18-20, so 4-6 years ago.
TinyTrip !5pb17tfZto - Wed, 13 Jun 2018 15:21:24 EST ID:80eiULCN No.141812 Ignore Report Quick Reply
It a proven interaction due to the isoenzyme pathway (I'm sure you know it but it's the same family that metabolizes roughly 60% of all RX medication from NSAIDS, steroids, benzos, opioids, CCBS etc
it's one reason why certain algorithms will distinguish if the patient tapering is a smoker and adjust accordingly.

Whether or not "noticing" it is placebo is another thing all together but I'd say its likely from what I've touched on the subject. The loss in efficacy doesn't seem anything other than minor.

I always laugh when I realize we're in the same age, I always assume you are older.
Dr. Katz !KqgSR25gAQ - Thu, 14 Jun 2018 22:29:41 EST ID:t8lReBf3 No.141827 Ignore Report Quick Reply
I always forget that you’re the same age as me. Really, I always thought you were a couple years older than me, too.
I was born in 1994 —- just turned 24 a couple of months ago.

full bump
Thomas Woblinglut - Fri, 15 Jun 2018 00:22:40 EST ID:VbPkri/c No.141830 Ignore Report Quick Reply
Fuck, I've been posting here forever and thought both of you were way older than me.

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