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L-Tryptophan to DMT by Jenny Heshwudge - Wed, 02 May 2012 00:59:07 EST ID:YQbWVG+F No.64387 Ignore Report Reply Quick Reply
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Can DMT be synthesized from L-Tryptophan?
6 posts omitted. Click Reply to view.
>>
Martha Sussleturk - Sun, 06 May 2012 18:02:08 EST ID:4iFSJIpl No.64475 Ignore Report Quick Reply
>>64469
Unstable in the body, yes. But who means in vivo when talking about stability? Don't be a dick until you get some learnins.
From TIHKAL:
>The phosphate ester, psilocybin, requires two additional steps: the conversion of 4-HO-DMT (as the sodium salt) to 4-(O,O- dibenzylphosphoryloxy)-N,N-dimethyltryptamine, with dibenzyl chlorophosphonate, followed by the catalytic removal of the benzyl groups with hydrogen and Pd on Al2O3 to give the phosphate ester of 4-HO-DMT (psilocybin). This product is much more stable in air than psilocin, and is water soluble.

Again, nobodies suggesting this. The yield is low. Still, if one made psilocin, they might want to go the extra step to make the more stable 4-AcO-DMT, even though it's converted to psilocin in the body. Not that this thread is about that.
>>
Shitting Niggerwell - Tue, 15 May 2012 20:47:58 EST ID:f+BXRDLI No.64679 Ignore Report Quick Reply
>>64469
Psilocin has a half-life that's measured in hours, but psilocybin has a half-life that's measured in months. Don't be so mean and bitchy, you just broadcast negativity, and also you were wrong.

Now apologize to Thomas Goodshit so we can go back to tripping.
>>
Albert Chirrymet - Wed, 16 May 2012 12:52:24 EST ID:RcT1Vdlu No.64691 Ignore Report Quick Reply
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Back on topic, could L-Tryptophan be extraction/isolated from 5HTP.

I recently read it was a precursor to 5HTP but this could just be wishful thinking.
>>
Wesley Blytheshit - Wed, 16 May 2012 17:12:46 EST ID:wMzzxY/S No.64694 Ignore Report Quick Reply
>>64691
Theoretically yes, but not easily. You would have to remove the hydroxyl group. http://www.orgsyn.org/orgsyn/prep.asp?prep=cv6p0150 Not sure if this method would work though.
>>
BigEX2C !l8koTkfoeM - Thu, 17 May 2012 20:02:29 EST ID:YmEd3M1V No.64722 Ignore Report Quick Reply
honestly man the body uses a very similar pathway when creating serotinin. It uses L-aromatic amino acid decarboxylase to convert the tryptophan to tryptamine, then it uses another enzyme (beta hydroxylase maybe?) to convert that to serotonin. The only issue here is that it is very difficult to replicate these enzymes without the proper lab tech. But this is not the most efficient way. Nature is much more efficient in this sense, this is why extraction is a much preferable method than synthesis.

as using chemicals, once again not very easy. you would need some sort of chemical cable of decarboxylating your amino acid in question, then another cabable of methylating your amine group, twice. Not a walk in the park without proper lab equipment. stick to extractions man

>>64445
I can't find any info on this chem. Did you perhaps mean 1,2,3,4 tetrahydronaphthalene?


Stupid question by George Chemmlehall - Tue, 15 May 2012 01:45:53 EST ID:6Jz53rlQ No.64656 Ignore Report Reply Quick Reply
1337060753661.png -(8739 B, 390x300) Thumbnail displayed, click image for full size. 8739
like any of you are here for science, but how does colour work?
Wavelengths, absorption, reflection, additive, subtractive and shit.
5 posts and 1 images omitted. Click Reply to view.
>>
Ferp Rickelderp - Wed, 16 May 2012 03:24:02 EST ID:YKzhpN/+ No.64687 Ignore Report Quick Reply
>>64680
Almost all atomic/molecular orbital shapes have resonances in the IR-visible-UV range. Extended conjugation like in methyl red for example.
http://en.wikipedia.org/wiki/Methyl_red
nb for dp
>>
op - Wed, 16 May 2012 23:06:32 EST ID:6Jz53rlQ No.64700 Ignore Report Quick Reply
So, which vibrations "produce"/re-emit/absorb which colours? Is there anyway to tell?

Thank you guys for answering
>>
Rebecca Gengerline - Thu, 17 May 2012 10:16:34 EST ID:dLr5LEtt No.64716 Ignore Report Quick Reply
>>64700

http://www.skidmore.edu/~hfoley/images/spectrum.jpg

you could have googled it as well
>>
op - Thu, 17 May 2012 13:12:50 EST ID:6Jz53rlQ No.64717 Ignore Report Quick Reply
>>64716
that wasn't really what I was trying to ask. More like, what determines what colour an object will/how is it determined?
>>
Albert Hangerspear - Thu, 17 May 2012 19:36:30 EST ID:5Mq3k0qI No.64721 Ignore Report Quick Reply
>>64717

Well guys already said it depends on what wave lengths molecules/atoms absorb.I'm not sure what you're asking but maybe you could read about IR spectroscopy so you get a feeling what happens with molecules and bonds when they are hit by photons.Different energy/frequency correlates with different types of movement of oscillators.Not saying that is the case here , but you mights get some intuition about this subject after that.


The Greatest show on Earth by Henry Brookspear - Thu, 17 May 2012 07:49:52 EST ID:7tlwi7Uq No.64713 Ignore Report Reply Quick Reply
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Can you guys tell me if I grasp evolution yet? Here's my summary

(Keep in mind I don't list all hominids, just key ones that lead to us)

>Stars

>Light Elements

>Heavy Elements

>Molecular life

>Primordial Soup in lakes

>Self-replicating molecule, forefather of DNA
Comment too long. Click here to view the full text.
>>
Rebecca Gengerline - Thu, 17 May 2012 08:47:38 EST ID:dLr5LEtt No.64714 Ignore Report Quick Reply
>>64713
>Can you guys tell me if I grasp evolution yet?
No you don't ..

Evolution is a theory about LIFE.It has nothing to do with elements, stars etc ..

Part that explains how life came to existence is abiogenesis.

http://www.youtube.com/watch?v=U6QYDdgP9eg
>>
Oliver Honeyshit - Thu, 17 May 2012 09:07:21 EST ID:nBhn/bG7 No.64715 Ignore Report Quick Reply
>Molecular life

Meaning what?

>Bacteria

The "first microbe" wasn't really a "bacteria" as such.

>Natural selection

This occurs straight after self replicating molecule, not after bacteria. Any replicating molecule undergoes natural selection, regardless of it it is actually a "cell" yet or not.

The rest seems fine, if simplified.
>>
James Subbergold - Thu, 17 May 2012 13:42:16 EST ID:SVs7eWa0 No.64718 Ignore Report Quick Reply
As >>64714 said, you're misunderstanding the reach of what evolution describes. The big bang produces the first elements that condense into starts. Stars collapse and produce heavier elements, which are deposited in the subsequently formed planets. The development of life from these non-living elements is abiogenesis. So these two first big steps, the big bang and abiogenesis are not described by evolution. Evolution is the progression of life.

Interesting side note though, the first 'molecular life' was likely self-catalytic RNA molecules, cool shit to think about.

>>64715
>The "first microbe" wasn't really a "bacteria" as such.

Kind of depends what you call a bacteria. There is fossil evidence of bacteria as far back as about 4.5 billion years.
>>
Hedda Bongerwuck - Thu, 17 May 2012 16:10:42 EST ID:xr8W4OW5 No.64719 Ignore Report Quick Reply
hydrogen,helium - stars - light elements - heay elements
in that order


chems chems chems by Shit Tillingfuck - Thu, 17 May 2012 00:02:03 EST ID:HukyWU3u No.64701 Ignore Report Reply Quick Reply
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I'm interested in procuring some chemicals and come to you, /chem/, to ask about the best way to do this(not online). At this point, what I need is Glacial Acetic Acid(99%+) and food grade Hydrogen Peroxide(35%). I'm aware that you can buy both of these off amazon/copBay but I'd prefer not to order this online and pay the hazmat fee. Could I obtain these in person at any chain store?

My second issue is finding a photo supply specialist store and/or lab supply house. Are there any chains that I could easily search for? What is the best way to go about finding these, google hasn't provided me with much help.
>>
Augustus Cravingnudge - Thu, 17 May 2012 00:29:37 EST ID:RcT1Vdlu No.64702 Ignore Report Quick Reply
>>64701
The only thing I can answer for you is pertaining to the H2O2. This can be obtained by simply heating up regular H2O2 until the water boils off. Waters B.P. is lower than H2O2 so it will just vaporize away leaving H2O2 until the desired concentration (which can be found with basic math). You don't want to concentrate it too much as it will easily decompose at higher concentrations and too much heat can cause combustion. I've used this method to synthesis Acetone Peroxide and it has worked very well. Heat slowly.
>>
Jenny Crirringhall - Thu, 17 May 2012 01:10:56 EST ID:uaHjhugm No.64703 Ignore Report Quick Reply
>>64702

Ah yes, duh. I could just heat up a dilute mixture on a hotplate until I reach the desired concentration(density equations). What about storage of this solution? Could I store it in the original container? Would I need to add some sort of stabilizer at this conc.?
>>
Augustus Cravingnudge - Thu, 17 May 2012 07:26:49 EST ID:RcT1Vdlu No.64712 Ignore Report Quick Reply
>>64703
I store mine simply in the original container like you said. I think at ~35% it will be stable in air and may even give it off a blue tint, it's when it reaches upward of 70% that I'm pretty sure you need a stabilizing agent.


LSA extraction by Emma Honeyhood - Wed, 16 May 2012 17:31:51 EST ID:mYf/+d3n No.64695 Ignore Report Reply Quick Reply
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So I want to extract LSA from morning glory seeds. I will be following this extraction guide,

http://www.erowid.org/plants/morning_glory/morning_glory_extraction2.shtml

And I would like to know if I can replace the methanol with isopropryl alcohol as the polar solvent.

Is this a suitable replacement or should I wait for my local home depot to re-stock on methenol? i understand that the isopropryl in denatured, but would drying the product out thouroughly help?

Also, to anyone who has performed this extraction before, how long does the petroleum ether take to evaporate?

Thanks a bunch guys.
4 posts and 2 images omitted. Click Reply to view.
>>
David Blatherhood - Thu, 17 May 2012 06:48:37 EST ID:mYf/+d3n No.64708 Ignore Report Quick Reply
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Dicks everywhere ect;
>>
David Blatherhood - Thu, 17 May 2012 06:49:53 EST ID:mYf/+d3n No.64709 Ignore Report Quick Reply
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This ones more sinister.
>>
David Blatherhood - Thu, 17 May 2012 06:53:08 EST ID:mYf/+d3n No.64710 Ignore Report Quick Reply
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Psychedelia stuff
>>
David Blatherhood - Thu, 17 May 2012 06:54:27 EST ID:mYf/+d3n No.64711 Ignore Report Quick Reply
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And finally, a full on delirious hallucination on a bus/subway.
>>
Nigger Smallbury - Thu, 17 May 2012 17:02:22 EST ID:Ayexs08i No.64720 Ignore Report Quick Reply
Don't use isopropyl alcohol. c'mon. You should probably learn more about chemistry in general before doing an extraction.
/nb


laying 25i-nbome on blotter by Lydia Fickleshit - Tue, 21 Feb 2012 18:41:37 EST ID:imTiBj91 No.62984 Ignore Report Reply Quick Reply
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ion exchange blotter of course. From freebase.
I've googled and could not really find a decent method.
3 posts omitted. Click Reply to view.
>>
Phineas Hurringkitch - Wed, 22 Feb 2012 10:09:39 EST ID:x3ziOGV5 No.63000 Ignore Report Quick Reply
>>62984
I'd just like to throw you a big fuck you if you plan on selling that as acid, I got permanent hppd from one trip off a mystery drug on 2 quarter inch tabs, I'd give tens of thousands of dollars to undo that, if you're selling it as 25i thats cool but laying drugs and selling them as acid is pretty much dosing people with mystery drugs with permanent effects without their consent, which means FUCK YOU, also I know people in the business who take this shit personally, and epic-dose knowingly lying dealers with whatever drug you're trying to push, expect us.
>>
Faggy Wagglepore - Thu, 23 Feb 2012 18:25:48 EST ID:6DP3nyh/ No.63033 Ignore Report Quick Reply
>>62995
The HCl is water-soluble.
Complexing it will not make it active orally. It just increases sublingual/buccal bioavailability.
Also seconding not to sell this stuff.
If you want to sell psychedelics, grow some shrooms, get a few sheets of acid and make some DMT.
Psychedelic RCs should be left to people who can at least google their IUPAC names. How high are the odds they're gonna buy from a dealer when they know enough about these drugs to handle them safely?
>>
Martin Blythefoot - Fri, 24 Feb 2012 13:10:02 EST ID:CAmffUCt No.63049 Ignore Report Quick Reply
>>63000

Seconding this, aside from the complete lack of ethics or conscience people who do this have they also lack intelligence and foresight.

You don't know who you're selling to, but people know you. People take this very seriously, and if something goes awry (ex. HPPD or adverse effects from a fucking RC putting someone in hospital) you'll have to be naive to think people won't find you and look for your head. It's not unheard of for people to put prices on limbs for things like this and unscrupulous shits who pull this kind of thing to wind up on the receiving end of a bat.
>>
Molly Nicklebanks - Sun, 26 Feb 2012 08:42:39 EST ID:pCdrkqJw No.63077 Ignore Report Quick Reply
>>63000
This, for sure.

You better tell people what it is, Lydia!!! Tell them it's not like acid, and it's not safe to take more than a couple hits (>500mics overall. Roughly). Well, it might be safe, but it might not. Don't fuck around with research chemicals.
>>
David Clessleshaw - Thu, 17 May 2012 03:52:35 EST ID:Tj/iqPSB No.64706 Ignore Report Quick Reply
>>62984
you from virginia?


Acid/Base question by Albert Chirrymet - Wed, 16 May 2012 12:44:06 EST ID:RcT1Vdlu No.64690 Ignore Report Reply Quick Reply
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Hey /chem/ this may be a stupid question but I am doing a caffeine extraction from Tea leaves. I was told to use a solvent that is miscible in water (the literature calls for Dichloromethane, which I understand is hard to come by,so I am using toluene) and a (perhaps diluted?) acid and base. My question is, since the writing asks for HCl and I do not have HCl but DO have conc. Sulfuric Acid (i'd say >90%), would it be possible to use the Sulfuric acid as a substitute? More general form: Can any acid be used to lower pH in an acid/base extraction or in most more practical applications is it strict?
>>
Basil Gabblefoot - Wed, 16 May 2012 15:46:04 EST ID:+wLIoc1T No.64692 Ignore Report Quick Reply
you have to look at the pKa of the compound you're extracting... the pH has to be close to the pKa. I think, sorry, just trying to get the ball rolling here. pretty sure you could use sulfuric acid
>>
Edwin Bunstock - Wed, 16 May 2012 19:42:10 EST ID:s7cuIvOm No.64697 Ignore Report Quick Reply
i might be talking out of my butt here but replacing any strong acid with another should be fine because they all dissociate completely, i don't know that it would make much difference.

it would matter if, for some other purpose, your literature called for one weak acid and you wanted to use another. in that case the dissociation constants of the two acids should be similar


Epic Tits by Priscilla Bunman - Tue, 15 May 2012 02:28:37 EST ID:GFokewa0 No.64658 Ignore Report Reply Quick Reply
1337063317505.jpg -(28940 B, 480x272) Thumbnail displayed, click image for full size. 28940
Hello /chem/

What volume of 0.150 M NaOH would be required to bring 12.0 mL of distilled water that has a pH of 7.00 to a new pH of 11.36?

I tried using c1v1=c2v2 and the Henderson-Hasselbalch equation but my final answer is wack.
>>
OrganicEuphoria !C5Eg6mdVac - Tue, 15 May 2012 12:41:15 EST ID:+CNh9Rq4 No.64660 Ignore Report Quick Reply
>>64658
Ya try using the Henderson-Hasselbalch eq?
>>
blup !NAMdiwz0Sw!!gihTcwet - Tue, 15 May 2012 13:38:28 EST ID:MaFEYvTk No.64662 Ignore Report Quick Reply
>Henderson-Hasselbalch equation
>strong base
pa lease.

Try doing this the mathematical way. Set what you can variate equal to x and then work from that. How does it relate to what you eventually want? Don't look at the spoiler unless you really really suck at this.

The most important things to know here are:
pH + pOH = 14 (if the original solution has a pH of 7)
[OH-] = 10^(-pOH)
[OH-] = absolute amount of OH- / amount of solution

pH + pOH = 14
required pH is 11.36, required pOH = 2.64.
[OH-] = 10^(-2.64) M
Say amount of 0.150 M solution added = x.
Comment too long. Click here to view the full text.
>>
Augustus Turveystock - Tue, 15 May 2012 20:04:40 EST ID:PcaXNhG4 No.64677 Ignore Report Quick Reply
can science tell me why women are such sluts?
>>
Nell Seffingtirk - Wed, 16 May 2012 17:39:08 EST ID:NtwSJHqu No.64696 Ignore Report Quick Reply
>>64677
Because the genes for an active sexuality have survived.


Quantum PHysics (or General Science) Textbooks by Edwin Grimwill - Mon, 14 May 2012 21:02:10 EST ID:LiUBhNVR No.64646 Ignore Report Reply Quick Reply
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So /chem/, I have a atrong interest in science generally and my academic life is dedicated to political science. I still have a strong interest in the physical sciences and would like to further my knowledge of them on my own time. I'm looking for any textbooks in the physical sciences that might be good, but I've had trouble finding particularly good and up to date quantum physics textbooks and so am looking for recommendations. It's always preferred if they're free of charge (legally or otherwise, doesn't matter) but I do have some funds saved up that I'm willing to spend. Any suggestions?

Pic tangentially related.
1 posts and 1 images omitted. Click Reply to view.
>>
Walter Heblingtadge - Tue, 15 May 2012 18:03:43 EST ID:X6+TFg7N No.64669 Ignore Report Quick Reply
>>64667

It's the American term for what is called Politics in the UK, and is presumably derived from the German name for the subject, Politikwissenschaft.
>>
Doris Nicklefoot - Tue, 15 May 2012 18:16:14 EST ID:acXRwlko No.64670 Ignore Report Quick Reply
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>political science
>science

Nope.jpg
And you don't just...learn quantum physics, holy fuck are you actually a savant?
>>
Hugh Tillingville - Tue, 15 May 2012 19:03:14 EST ID:4iFSJIpl No.64675 Ignore Report Quick Reply
>>64670
Don't listen to this dick

Get QED by Richard Feynman. It's a great, in depth introduction to quantum physics. You can probably find a pdf online.

> I've had trouble finding particularly good and up to date quantum physics textbooks

Even the earlier textbooks are still "up to date." Dirac's textbook is still all correct (at least, I think so). The problem is you need a solid understanding of classical physics, differential equations and linear algebra to start to go through it. If you want the same understanding that a physics grad has, you really need those pre-reqs. Otherwise, Feynman's QED is your best bet.
>>
Hugh Tillingville - Tue, 15 May 2012 19:04:53 EST ID:4iFSJIpl No.64676 Ignore Report Quick Reply
>>64675
Also, if you do know calculus, you might want to check out the quantum physics chapters in Atkin's Physical Chemistry. Still very difficult.
>>
Fanny Dreddlebanks - Wed, 16 May 2012 16:36:06 EST ID:nR/hDKJN No.64693 Ignore Report Quick Reply
the integral of democrat from economics to social issues = communism


Cheap chemistry sets by John Chimblepeck - Tue, 15 May 2012 17:40:12 EST ID:8b8sC43l No.64668 Ignore Report Reply Quick Reply
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Hi /chem/,
I am interested in synthesizing some delicious mdma. As you are very well aware chemistry sets are expensive, and if you look for parts individually, are a hassle. Where do you go for your equipment? What sets are cheap and durable? What is your personal recommendation?

Thanks!
>>
Phineas Sorringtidge - Tue, 15 May 2012 18:30:26 EST ID:s0Son4FW No.64672 Ignore Report Quick Reply
>>64668
>>
Hugh Mizzleville - Tue, 15 May 2012 22:16:17 EST ID:PhcKMowM No.64682 Ignore Report Quick Reply
eBay mostly.

I would put in a great deal of research and planning before you embark upon this endeavor. What kind of experience do you have, in the classroom and lab? I would read up on basic lab techniques such as fractional and vacuum distillations. I would also recommend this as the most accessible pathway for an amateur chemist:

  1. Distillation of sassafras to get safrole
  2. Isomerization of Safrole with KOH and CaO to isosafrole
  3. Epoxidation of isosafrole via a peracid (peracetic acid)
  4. Reductive Amination with AlHg and Nitromethane

Be especially careful on the reductive amination, as its condition are very picky. I would follow mm's instructions to a fucking tee here. And I give you this link: http://www.erowid.org/archive/rhodium/chemistry/index.html

Everything you need to know about the synth should be on there. Dr. Drool's synth is a good starting point, but it is somewhat outdated and peracid epoxidation is alot more accessible(completely OTC) with better yields than the classic Wacker Oxidation.

Here's another good thread to keep you grounded and to make sure you don't do anything retarded.

http://www.psychonaut.com/synthetics-extraction-research/35566-5-mistakes-i-made-you-shouldnt.html
>>
Polly Birringfedge - Wed, 16 May 2012 12:02:37 EST ID:Ek4SJetS No.64689 Ignore Report Quick Reply
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>>64682
my nigga


Preparing for the MCAT by Lillian Ficklechick - Tue, 15 May 2012 23:17:42 EST ID:iKDqXI0H No.64683 Ignore Report Reply Quick Reply
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Hello everyone. Right now I am preparing for the MCAT in the fall, and am currently studying this summer for them. Is there any online websites/programs to download or pirate that can help me prepare for them? Right now I'm reading the Exam Krackers book, but that's about it. Thank you in advance.
>>
Martha Grandwill - Wed, 16 May 2012 06:49:35 EST ID:4iFSJIpl No.64688 Ignore Report Quick Reply
>>64683
IDK, but /med/ might.


Favourite substance - follow my lead... by Martha Sunkingold - Mon, 14 May 2012 20:55:06 EST ID:1Hoby4wy No.64645 Ignore Report Reply Quick Reply
1337043306963.jpg -(396977 B, 1280x1024) Thumbnail displayed, click image for full size. 396977
A liquid hydrocarbon of the alkane series.
Chemical formula: C6H14
Colorless, transparent liquid
boiling point between 50 and 70 °C, with gasoline-like odor.

Hexane[%]
3 posts and 1 images omitted. Click Reply to view.
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Martin Sazzleham - Tue, 15 May 2012 00:07:59 EST ID:+wLIoc1T No.64654 Ignore Report Quick Reply
>>64647

why did you spoiler all of the names of those compounds, but then give a chemical formula with two oxygen atoms? none of the compounds beneath your spoilers contain oxygen.
>>
Oliver Pummerforth - Tue, 15 May 2012 00:12:31 EST ID:gYEsJ68q No.64655 Ignore Report Quick Reply
>>64654

Those were 5 chemical species which all met OP's description
>>
blup !NAMdiwz0Sw!!gihTcwet - Tue, 15 May 2012 13:24:47 EST ID:MaFEYvTk No.64661 Ignore Report Quick Reply
>>64647
I'm guessing 1-(4-methoxyphenyl)propan-1-one, but the NMR shift my program predicts gives a different shift for the methylene carbon in the main chain then you have in your picture.
>>
Jarvis Sanningford - Tue, 15 May 2012 18:41:49 EST ID:ODnPdhJ6 No.64673 Ignore Report Quick Reply
One of the best ligands due to its ability to participate in "back bonding"
The foundation of the whole of organometallic chemistry
Is part of most of the important organic functional groups

CO
>>
Emma Ginnerstone - Tue, 15 May 2012 20:19:57 EST ID:gYEsJ68q No.64678 Ignore Report Quick Reply
>>64661

You have it.

IDK why that might be. I pulled it off a practice website, so it's possible it was manufactured to be legible. Those splitting patterns are a little too clean for an actual machine reading imo.



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