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Phalaris Extraction Thread by Ian Ciffingbidging - Sat, 28 May 2016 12:28:20 EST ID:cOHpZlwa No.77923 Ignore Report Reply Quick Reply
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Has anyone here done any work with extracting DMT or other trptamines from various specieis of Phalaris grass? DMT Nexus has a lot of information but a lot of it is contradictory and incomplete.
Esther Diddlemene - Sun, 29 May 2016 16:25:14 EST ID:alUhohOf No.77931 Ignore Report Quick Reply
I wouldn't bother. I'd just purchase Acacia Confuse or Mimosa Hostilis online.
Molly Honningshit - Tue, 14 Jun 2016 11:24:06 EST ID:DXmzOHk9 No.77967 Ignore Report Quick Reply
Once you have the real materials its super easy, I made some yuasca in my dorms on a freakin hot plate.
Oliver Clepperdale - Wed, 15 Jun 2016 01:23:52 EST ID:vp89ZYzI No.77968 Ignore Report Quick Reply

Stop being so afraid and jump into it. Vaporize it ideally.

liquid weed by Verotos - Mon, 13 Jun 2016 17:05:06 EST ID:DXmzOHk9 No.77966 Ignore Report Reply Quick Reply
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So my question is, how much thc, cbd,(weed) can 1 gallon of 100% VG absorb? I'm stoned and forget the term, deal with it lol

Chlorine Biosphere? by Thomas Bollynog - Mon, 06 Jun 2016 14:04:43 EST ID:QeFTOZ30 No.77943 Ignore Report Reply Quick Reply
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I'm an artist that depicts space scenes. Rather than focus on scifi space battles or nebula or some shit I like to focus on making realistic-looking planets (or as realistic as I can get them to look at least). I do a lot of Earth-like planets but, as a biology nerd, I wanted to try something new. I've done a few Earth-like planets with usual colors of vegetation: red, purple, black, etc. I've been reading about alternative biochemistry and wanted to try depicting a planet with a biosphere that isn't necessarily carbon-aqueous.

Anyways, I'm not here to talk about the planet in particular. This isn't /sagan/ after all. No, I want to discussion biochemistry involving chlorides. I read a study about some scientists replacing the thymine in the DNA of E. coli with 5-Chlorouracil, so there is some precedent for chlorides being incorporated into biological systems. In my research I also came across this: 2HCl + CO2 ---> CH2O +Cl2. It looks kind of like some kind of photosynthesis that uses hydrochloric acid to form organic compounds? I'm pretty sure that's formaldehyde and chlorine gas. Do you think that the chlorine gas could be utilized in a manner similar to oxygen? Could this create any kind of sustainable biosphere? I'm honestly not sure this concept is even remotely possible but it is interesting.
1 posts omitted. Click Reply to view.
Bombastus !RZEwn1AX62!!xXxJO70U - Thu, 09 Jun 2016 21:27:23 EST ID:4ppVjZXo No.77952 Ignore Report Quick Reply
Chlorine wouldn't be prevalent enough in the hydrosphere or atmosphere to be used by major biological creatures.
There are a few species of tiny algea and bacteria that CAN metabolize chlorinated and brominated substances for energy but not as their main fuel source. They also excrete simple chloro-carbon compounds like mono-chloromethane and chloroform. It gets to be an issue when they release a lot of this shit into the atmosphere.
Their chlorine source is located on vents in the Earth's crust from decay and slow reslease of built in gasses. Then they escape into the atmosphere and then into space.
You would need a planet with ridiculous gravity to keep chlorinated compounds low enough. But that would also crush a lot potential life candidates.
Ian Werrypan - Sat, 11 Jun 2016 01:44:16 EST ID:DpF94DTG No.77961 Ignore Report Quick Reply
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Flourine? Might be interesting.
I got the photosynthesis reaction from here:
The 5-Chlorouracil info I go from skimming through this paper:

How ridiculous are we talking? I don't think higher gravity is necessarily a big hinderance to complex life. Imagine what Martians would think about the appearnace of life on a world with Earth's amount of gravity, after all. There is a point, however, at which gravity would definitely preclude anything but microbes from evolving. Of course there's still possibilities with that. Perhaps an ecosystem of slime mold-like organisms? I'm unsure what the diversification potential of slime is but I'm sure natural selection could come up with some interesting stuff even if I can't.
Bombastus !RZEwn1AX62!!xXxJO70U - Sat, 11 Jun 2016 11:15:13 EST ID:4ppVjZXo No.77962 Ignore Report Quick Reply
Jupiter level gravity. The gravity would be so strong that life would not exist due to the activation energy to sustain wall membranes would be too high. It's just theoretically so implausible for it to work.
Methane would be the other best bet as it can be burned for fuel relatively easily and would be so abundant in the universe. Carbon fixation comes first; then nitrogen fixation.

On a low pressure system, it's hypothesized that silicon would be the binding site of choice due to its molecular weight. In this case, you might have gaseous bromine sticking around. However, it would be so implausible because the halogen % composition of the universe is so miniscule, the odds are just heavily stacked against your favor of a halogen- based organism.

Oxygen is the best candidate because it's heavy enough to stay on the atmosphere, be gaseous, and most importantly: is abundant enough in star death.
Bombastus !RZEwn1AX62!!xXxJO70U - Sat, 11 Jun 2016 11:16:15 EST ID:4ppVjZXo No.77963 Ignore Report Quick Reply
Uracil is made after multiple millions of years of carbon fixation and added nitrogen fixation. No way such a complex structure would exist otherwise, unfortunately.

Edwin Fupperstodge - Sat, 11 Jun 2016 23:34:49 EST ID:GSuYkmZT No.77964 Ignore Report Quick Reply
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Seems like this idea is a bust. Oh well, thanks for the input anyways. It's always nice to learn something, even if it leads to disappointment.


H2SO4 by Burney - Tue, 10 May 2016 23:12:56 EST ID:V/Jmd1aC No.77888 Ignore Report Reply Quick Reply
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I acdentely 98% pure sulefuric acid. Should I have this checked out? Could be a third degree chemicle burn? Should I just ingore it and hope it goes away. Also this happened a few days ago so this isen't a fresh wound.
Jarvis Bicklestirk - Wed, 11 May 2016 10:07:58 EST ID:QpnKQ24z No.77889 Ignore Report Quick Reply
hard to tell but id guess youre right about it being thrid degree. since its that severe and a few days old, expect permanent scar tissue

dont just ignore it. how big is it? kind of hard to tell, shouldve put a lime next to it for scale.

make sure it doesnt get infected and get some burn cream. keeping it wet with that creme really speeds up the healing process and keeps scabbing or scarring to the minimum.
Nathaniel Brooklock - Fri, 20 May 2016 18:49:00 EST ID:j2okwtbe No.77899 Ignore Report Quick Reply
I hope you put that under running water
Bombastus !RZEwn1AX62!!xXxJO70U - Wed, 25 May 2016 21:14:28 EST ID:aXFxXtc6 No.77914 Ignore Report Quick Reply
>I acdentely 98% pure sulefuric acid.

You should be fine, OP. Acid burns are normally very localised and don't cause any damage on your flesh that isn't superficial. As long as you're not using it as an inhalant, huffing it, using it as eyedrops, injecting it, plugging it, or bathing in it, this burn will just be like a tattoo.
What you have to worry about is potential infection.

How'd you let that happen to you, anyway? I've accidentally poured H2SO4 on the back of my hand before and washed it off within 20 seconds while it was already burning. How'd you let it get to that extreme?
Shit Basslesadge - Fri, 10 Jun 2016 19:11:42 EST ID:zwhzKcaA No.77958 Ignore Report Quick Reply
Keeping the sunlight(UV) off of it should also help reduce scaring. Cover lightly.

I'm a dumb ass. by Shit Basslesadge - Fri, 10 Jun 2016 19:04:12 EST ID:zwhzKcaA No.77956 Ignore Report Reply Quick Reply
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Why won't my shitty bottle crank fully dry out: It's kind of waxy. Seems acidic. Also burns toward the end of evaporation.
Shit Basslesadge - Fri, 10 Jun 2016 19:04:45 EST ID:zwhzKcaA No.77957 Ignore Report Quick Reply
Google absolutely refuses to help me.
Shit Basslesadge - Fri, 10 Jun 2016 19:27:34 EST ID:zwhzKcaA No.77959 Ignore Report Quick Reply
This is the only time this has occurred; Generally I get a nice fluffy white substance that evaporates cleanly, so I'm a bit confused as to what I changed. Under-reduced?

Future LSD Analogs? by TheDiggityDank !jmUcEJD43k!!E9WUPA0s - Fri, 29 Apr 2016 05:18:06 EST ID:7x9SM9m4 No.77870 Ignore Report Reply Quick Reply
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Hey guys, I had an idea for new possible LSD analogs. All important details are in the attached image, I am curious to see what all your thoughts will be on this!
Doris Wurrytack - Fri, 29 Apr 2016 15:28:22 EST ID:TZRaxcWf No.77871 Ignore Report Quick Reply
I'm only part way through my degree, so I could be wrong, but I don't see halogenated amines very often. I have no idea how you would add a halogen to that N, but it seems like it would be difficult to make/unstable. Interesting idea though, curious to see what others have to say
TheDiggityDank !jmUcEJD43k!!E9WUPA0s - Fri, 29 Apr 2016 17:54:30 EST ID:7x9SM9m4 No.77872 Ignore Report Quick Reply
Yeah, I have no real knowledge about the synthesis of these compounds, and I lack a fair bit of chem knowledge outside of more basic things like structural formulas etc. I do however have an alright amount of knowledge when it comes to Structure Activity Relationships in psychoactive compounds. This is why I came to you guys, as I you guys might have a greater understanding on this topic.
Charlotte Shakeham - Sun, 15 May 2016 19:41:26 EST ID:+5AM2MwN No.77891 Ignore Report Quick Reply
Does anyone know how these break down in the body? Probably the one that is most risky is the bromine one. LSD is in microgram doses so this probably isn't a risk but the bromide ion does have a long half-life in the body. As a rough estimate, if someone does 800 000 100 ug blots a day for 12 days straight they might run into problems but maybe I'm missing something.
Bombastus !RZEwn1AX62!!xXxJO70U - Wed, 25 May 2016 21:10:53 EST ID:G8mu3scS No.77913 Ignore Report Quick Reply
Hey Press. Get over here and check out these N-X bonds (where X-Cl,F,Br,I).

I don't think these would be stable at all. Google the stability of chloramine and their reactions. I know mono-chloro-amine hydrolyses into ammonium and chlorine gas. I don't see how these compounds would be stable given the first chance at a proton source and create the R2N-H bond.

If you want to make it a relatively good leaving group and available for adaptation in the body, I would highly recommend an Acetyl or a Tosyl group on that nitrogen. Tosylic acid is toxic to your kidneys but maybe at light concentrations like 1mg in the blood stream, it could be fine.
I wonder if you could make di-tosylic-morphine as a better alternative to heroin................ hmmmmmmmm.............................................

Organobromides are toxic to your liver and endocrine system. However, aromatic bromides are either excreted in your urine, safely or made into HBr and then NaBr which are safe enough in low concentrations. Not of a concern.
Examples: Bromovanilin, Bromazepam
TheDiggityDank !jmUcEJD43k!!E9WUPA0s - Fri, 10 Jun 2016 00:48:00 EST ID:aNLlWMG5 No.77953 Ignore Report Quick Reply

Thank you for the thorough explanation! I suspected that might be an issue, but I was just not sure if having the nitrogen of the amine group bonded into a more complex structure, as it is in LSD, would alleviate the issue. I have been looking into other potential LSD analogs, and I have come up with a few interesting hypothetical structures. However, I really do not know enough about lysergamide structural activity relationships to know if they would be active or not.

CWE and saturation by Cyril Cremmerwat - Wed, 18 May 2016 13:54:30 EST ID:9YAuxRQ8 No.77896 Ignore Report Reply Quick Reply
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I've been wondering about some thing regarding CWE. The main point of CWE with products containing APAP seems to be to reduce the amount of APAP in the final product since it seems to be more water soluble than I thought it was. Which means the less water you use and the colder it is, less APAP will be in the final product. Which led me to some questions:

  1. Assuming that you have a drug containing Codeine Phosphate and APAP. Could you, in theory, dissolve the pills in say 10ml of water ("One gram [of Codeine Phosphate ]dissolves in 2.3 ml water,", O'Neil M. J. (ed.), Smith A. (ed.), Heckelman P. E. (ed.)-The Merck Index_ An Encyclopedia of Chemicals, Drugs, and Biologicals (1996)) and have some kind of "super concentrated", crystal clear solute of Codeine Phosphate with a ridiculous low amount of APAP? Or would the filter clog up? Or the solution get over-saturated? Which leads me to my next question

2. Both APAP and Codeine Phosphate are soluble in water. I don't understand the mechanics of dissolution completely but would it be possible to not have any 'space' left to dissolve the Codeine Phosphate? Or does it get dissolved first because it's so much more soluble? Or does it work completely different?

Recrystallizing APAP is a bother to me so by exploiting the great solubility of Codeine Phosphate I could in theory use cold water from the fridge or something. Maybe dissolving the pills in 50ml? Even at 20C this would leave me with 639mg of APAP which is a joke. (https://en.wikipedia.org/wiki/Paracetamol)
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Bombastus !RZEwn1AX62!!xXxJO70U - Sat, 04 Jun 2016 05:07:04 EST ID:z4/bY936 No.77941 Ignore Report Quick Reply
Awful meme magic
Vehk !7HYGxe5v5c - Mon, 06 Jun 2016 17:02:17 EST ID:AEFFwJfE No.77944 Ignore Report Quick Reply

For a beginning, Central Science is good and it's what I use for foundational chemistry revision. If you want a good general book for Organic Chemistry in specific, Central Science isn't useful. I'd recommend Claydens, it's comprehensive and structured in an accessible manner.
press !QUHukXEvkY - Wed, 08 Jun 2016 16:11:39 EST ID:fcMijPsC No.77946 Ignore Report Quick Reply
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well shit. apparently my version of claydens is too big for 420chan even compressed. a tiny low res pic thats 30mb big is mighty suspicious anyways.

but it shouldnt be too hard to come by
Edward Fanningdodge - Thu, 09 Jun 2016 11:43:00 EST ID:D9t26pna No.77948 Ignore Report Quick Reply
what the fuck is wrong with you
press !QUHukXEvkY - Thu, 09 Jun 2016 13:57:30 EST ID:fcMijPsC No.77949 Ignore Report Quick Reply
why dont you try opening it in winrar?

Ant level of consciousness by Samuel Tootworth - Sun, 05 Jun 2016 20:11:52 EST ID:92gUf0sA No.77942 Ignore Report Reply Quick Reply
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What would it be like to be an ant? Would you "feel" anything? Would you be able to think? Would you know that you're an individual or would you have no free will and just be a little organic robot that does whatever the colony needs?

Theory against science: gravity by Beatrice Tillingway - Tue, 02 Feb 2016 01:26:43 EST ID:vzB5izFF No.77606 Ignore Report Reply Quick Reply
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I have a theory on what could cause gravity that may go against popular science and I was wondering what people may think about it.

Gravity is caused by the sun. It is a condensed ball of molecules that has a reaction happening that need to be fed. It does not burn like a fire because it is an intense chemical reaction, but like a fire it needs to be fed to continue "burning". It pulls matter, including planets, towards it, and as these planets are pulled towards it it is spiraled around the sun, sort of like a toilet flushing. The sun pulls these planets towards it and as they travel towards the sun in a spiral they have a gravity created on them, much like an increase of gravity when you are spun around at a high speed on a park ride or on a astronaut g-force training machine. The gravity of the earth that is created by the sun can also spiral objects towards it, which results in the moon that spirals around the earth (but will eventually will be caught in an orbit and will stay at all times in one part of the earth. Look it up). Perhaps what will happen to the moon will happen to the planets as well, who knows. But this is just a theory that came to my head and that I was wondering what other people thought about.
press !QUHukXEvkY - Tue, 02 Feb 2016 10:09:18 EST ID:IoTC8+tS No.77607 Ignore Report Quick Reply
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okay so since this doesnt seem to be a common copy pasta;

  1. there is no chemical reaction occuring in the sun or any star
>under the conditions in a star no molecule can form, for the most part the matter of a star isnt even compromised of atoms but rather of broken down atoms
2. the actual process is fusion https://en.wikipedia.org/wiki/Nucleosynthesis, which is triggered by huge masses of gasses "gathering"
3. that gathering is actually caused by gravity
>this is a common process. for example jupiter as a gas giant couldve turned into a star if he had reached the critical mass to induce the aforementioned process
4. the sun actually expells matter because of the process
>allthough photons have no resting mass (dont quote me on that) they get expelled, same goes for hot gasses
5. the moon already is in orbit around the earth, same goes for the earths path around the sun.
>look it up
6. if your hypothesis was valid any kind of object that exerts gravity on other objects would need to perform a "chemical reaction", as you said.
>even pieces of rock drifting around in space exert gravity on other rocks

Cyril Brookstone - Fri, 06 May 2016 10:27:12 EST ID:46/eGtv8 No.77881 Ignore Report Quick Reply
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The increase in gravity caused by movement is in fact inertia, and aside from that, their are free agent planets that aren't orbiting any sun and indeed still have gravity.
Nb young einstein do more research before you come up with a theory.
Albert Tillinglock - Mon, 30 May 2016 08:45:50 EST ID:PYwdfvCt No.77933 Ignore Report Quick Reply
This isn't how scientific theories work, theories are based on evidence. This is just some stuff you made up.
Albert Tillinglock - Mon, 30 May 2016 08:47:00 EST ID:PYwdfvCt No.77934 Ignore Report Quick Reply
nb dammit, nb

LSD and Light Spectrums by Priscilla Cludgeville - Mon, 16 May 2016 20:11:19 EST ID:lbU1QW82 No.77892 Ignore Report Reply Quick Reply
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I don't understand how during the synth of LSD during a certain part a spectrum of light needs to be present to complete a step.
press !QUHukXEvkY - Tue, 17 May 2016 13:38:55 EST ID:QpnKQ24z No.77893 Ignore Report Quick Reply
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are you sure you know the difference between absence and presence?
Eugene Bledgeway - Tue, 17 May 2016 16:42:24 EST ID:ivgwSmOo No.77894 Ignore Report Quick Reply
I agree but two people have said this so far and I don't understand.
press !QUHukXEvkY - Tue, 17 May 2016 17:05:33 EST ID:QpnKQ24z No.77895 Ignore Report Quick Reply
is this some kind of netjester experiment where you try to randomly generate replies?

theres a lot of chemistry that requires certain frequencies of light, but photosensitive chemicals such as lsd require the absence of certain frequencies of light.

you dont need to have certain light in the synth of lsd in order to synth it, you just need to omit certain wavelengths in order not to have it degrade. this kind of shit is why there are a lot of flasks that are made from brown glass.
Ernest Pockham - Wed, 18 May 2016 15:53:33 EST ID:R2l5z5+y No.77897 Ignore Report Quick Reply
Someone I respect said it and I'm like wuuuutt and then I read it as a random post on the future so I didn't understand it.

Thanks for clearing it up.
Bombastus !RZEwn1AX62!!xXxJO70U - Wed, 25 May 2016 20:47:11 EST ID:Ym/MkWsP No.77911 Ignore Report Quick Reply
I believe the synth route calls for a certain wavelength of light in so that you're not working in the dark.
The experimental procedure probably assumes your knowledge of photodegradation and tells you to use x-y spectrum of light because x-z and x-a will degrade it.

For example, if one compound degrades in both UV and IR light, you should avoid light sources that are active in the 200-480nm and 650-900nm region. I would probably write the experimental procedure saying "use this cheap light I can find at Home Depot that only emits light at 550-600nm. This is so that you can still fucking see while doing your reaction.

Anyone know of this or anything similar? by HarryVonFlappinvag - Wed, 25 May 2016 16:41:28 EST ID:9AVsKPcg No.77908 Ignore Report Reply Quick Reply
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I hope this is a good place to ask this. I'm curious to know if anyone has heard of a med called Proglumide &/or is there a way to obtain it or create it or something similar. I think this med originally started as a stomach med but had the side effect of reversing people's tolly to opi's. From what I can remember reading yrs ago, this med worked best if taken for 3-4 days than take a 2-3 day break from it. Ofcourse it's not scribed anymore. This could be of such great help to the countless amounts of people who have to take opi's every day to deal w/pain. I guess we can thank the govmt or big pharma for taking something like this off the market, money is more important.
So my questions are this, does anyone know if this med can be obtained anywhere &/or could this med be created? Would it be possible to create something like it?
Aside from all the common potentiators I can't think of anything that would actually reverse a tolly to opi's, except in a round about way, DXM.
Thanks so much for any input any one is able to provide!

Phenethylamine naming by Ernest Blackcocke - Sat, 16 Apr 2016 01:53:53 EST ID:zsw9I8fO No.77844 Ignore Report Reply Quick Reply
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How can it be called phenethylamine when that clearly is a propyl group?
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Betsy Sillybure - Wed, 20 Apr 2016 19:04:47 EST ID:W92KPdIu No.77856 Ignore Report Quick Reply
I call bs shulgin lists the dosage of pea as upwards of 1.6g in pikhal.
press !QUHukXEvkY - Thu, 21 Apr 2016 09:11:06 EST ID:xFG0CGS+ No.77858 Ignore Report Quick Reply
oh come on.

did you copy that fantasy out of william gibsons neuromancer?
>The drug hit him like an express train, a white-hot column of light mounting his spine from the region of his prostate, illuminating the sutures of his skull with x-rays of short-circuited sexual energy. His teeth sang in their individual sockets like tuning forks, each one pitch-perfect and clear as ethanol. His bones, beneath the hazy envelope of flesh, were chromed and polished, the joints lubricated with a film of silicone. Sandstorms raged across the scoured floor of his skull, generating waves of high thin static that broke behind his eyes, spheres of purest crystal, expanding...The anger was expanding, relentless, exponential, riding out behind the betaphenethylamine rush like a carrier wave, a seismic fluid, rich and corrosive.

Sidney Cunningway - Mon, 02 May 2016 03:05:04 EST ID:56ToYEXS No.77873 Ignore Report Quick Reply

and that is why you stay in school kids
Nathaniel Brooklock - Fri, 20 May 2016 18:58:54 EST ID:j2okwtbe No.77900 Ignore Report Quick Reply
It is in some pre work out supplements, which people obviously feel some effect from so I wouldn't say it's dosage is around 1.6kg
press - Wed, 25 May 2016 16:30:23 EST ID:fcMijPsC No.77907 Ignore Report Quick Reply
im afraid thats not a very sound reasoning.

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