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Chemistry for retards by Doris Bablingstone - Thu, 06 Aug 2015 20:52:30 EST ID:NkniuLXa No.76880 Ignore Report Reply Quick Reply
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What are some good introduction's to chemistry, I don't even know the periodic table of elements so what I need is babby chemistry.

I do have General Chemistry by Linus Pauling but its pretty over my head.
>>
Nell Firrynock - Fri, 07 Aug 2015 08:55:42 EST ID:suDCfAlN No.76881 Ignore Report Quick Reply
>>76880
Here's a free MIT introductory chemistry course.
You have all the lecture notes available, the only thing unavailable is the actual reading, which you can substitute by just reading more on what they cover in the notes on wikipedia or something.
You can pick and choose which topics you want to learn about as well.
You can also look into other free courses.
http://ocw.mit.edu/courses/chemistry/5-111-principles-of-chemical-science-fall-2008/readings-and-lecture-notes/


420 Science by George Brevingketch - Wed, 24 Jun 2015 11:33:35 EST ID:YKD73kVj No.76721 Ignore Report Reply Quick Reply
File: 1435160015743.png -(2764B / 2.70KB, 189x148) Thumbnail displayed, click image for full size. 2764
Hey Guise. Started researching the possibility of analyze the redness of the eyes to determine the levels of "high".
Ended up making this android app: https://play.google.com/store/apps/details?id=com.dowrow.high_o_meter_free
9 posts and 1 images omitted. Click Reply to view.
>>
Bombastus !!HToBa9dh - Wed, 15 Jul 2015 17:13:25 EST ID:vbS8CtHn No.76811 Ignore Report Quick Reply
>>76807
No one I know will even touch their eye to anything to gauge how high they are.
No offence, OP, but you're incredibly out of touch with your costumer base. Holy bejebuz, mate.

NB.
>>
Alice Clayridge - Wed, 15 Jul 2015 18:51:41 EST ID:cM6rhCgJ No.76812 Ignore Report Quick Reply
>>76811

I think you're out of touch with what the market wants.

It's just a minor incision, you press the needle or blade into the eye and collect a blood sample. SIMPLE! Even a lazy stoner couldn't fuck it up. And then they know how high they are.

I was thinking of making a stoner scale. Like snoop dog heads. Half a snoop dog means you're buzzin. Five snoop dogs means the rooms spinning.

You'll have to make them disposable though so they aren't sharing needles with their friends tho.
>>
Bombastus !!HToBa9dh - Wed, 15 Jul 2015 19:53:03 EST ID:vbS8CtHn No.76814 Ignore Report Quick Reply
>>76812
Propose it on /weed/, then. See what they say. Maybe O'm wrong.

I don't know about you, but nothing touches my eye except my forearms and some water. And I know I'm not the only one who feels like this.
>>
Basil Pindermat - Fri, 31 Jul 2015 07:30:50 EST ID:cBr2UiWk No.76866 Ignore Report Quick Reply
Wouldnt this be impossible to use this as a scale? For myself, I cant recognize the redness always having much to do with how high I am. It depends on so many things, and also sometimes when you dont have red eyes, you look in the mirror and you do!

Things like are you already tired but trying to keep awake? That puts strain on the eye. Theres too much light where you are at to your high eyes. Sometimes I get red eyes just going outside with barely any wind. Id say the giveaway factor to it is the fogginess of the eyes.

Maybe find out what exactly gives you red eyes, in depth. Because most of the time you dont get red eyes.
>>
3am !/sly9iFJgg - Tue, 04 Aug 2015 09:38:55 EST ID:9h2+e35x No.76873 Ignore Report Quick Reply
They've already discovered how to gauge metabolites of THC which enter the bloodstream immediately after use. IDR offhand, but there's a specific one which is not psychoactive and is a telltale sign of recent use (versus traditional tests which use residues that last for weeks or months, in rare cases).

You can't really rely on symptoms of use as a metric, because cannabis is SO varied in its effect/cannabinoid composition. One of the reasons I don't like many dab batches is because the extraction methodology often excludes non-volatile components which alter the chemical nature of the cannabinoids, so sub-professional-grade dabs are no "clean slate" for comparison either.


Phenylacetic acid by George Siffingworth - Fri, 05 Jun 2015 14:54:14 EST ID:ykDmWZpt No.76624 Ignore Report Reply Quick Reply
File: 1433530454585.jpg -(26248B / 25.63KB, 640x286) Thumbnail displayed, click image for full size. 26248
Hello, /chem/!
I was wondering about this route to phenylacetic acid, and couldn't find it on the internet. Would the following synth work?

>Benzene is reacted with chloroacetic acid in the presence of aluminium chloride catalyst to yield phenylacetic acid. Would the aromatic ring attack the chlorinated position of the acid or the carboxylic one?

Thanks guys!!



Actually, I'm NOT willing to make P2P. I'm willing to make MDP2P, and as such, I woudn't be performing the above reaction with benzene, but with methylenedioxybenzene. So I was also wondering whether or not the AlCl3 would be a problem for the methylenedioxy ring. Would it be demethylenated by this catalyst? If so, I could perform the alkylation with chloroacetic acid before performing the methylenation of pyrocatechol with H2CI2 or H2CSO4. Problem is, in this case I imagine that the phenolic -OH groups would attack the chloroacetic acid instead of the aromatic ring doing the nucleophilic attack.

Any input on the above?
Thanks again!
15 posts and 4 images omitted. Click Reply to view.
>>
Bombastus !!HToBa9dh - Sat, 20 Jun 2015 14:24:48 EST ID:4ppVjZXo No.76703 Ignore Report Quick Reply
>>76702
Actually, I'm reflecting on this again.

I'm at non-chem related job right now so I don't have access to chemdrawzzz. But my current understanding of aluminium halide catalysed de-o-methylation forms that weird negative aluminium anion complex with the MeO (much like in F-C alkylation). Then a bound halide should attack the methyl group spawning the leaving MeX (MeCl) and generating that as a gas (like all o-demethylations do). Then you can hydrolyse the system to generate the phenol.
It also doesn't seem to be a catalysis as AlCl3 is reacted away.

Reflecting on it further, I don't see why it wouldn't happen, albeit very slowly. I think it wouldn't be worth it since it should exist in equilibrium with the product <-> reagent when it even is demethylated because the chloro-alkane formed would immediately react with the hydroxide to reform the methine-dioxy-benzene.

I'm confident enough in that answer and will revisit when I have more time during the day.
>>
Nathaniel Shakewill - Sat, 11 Jul 2015 01:03:40 EST ID:h6BiFOLD No.76794 Ignore Report Quick Reply
>>76702
What Bombastus said here. The Dioxy-methine bridge is generally pretty stable due to conjugation. See if you can find a table of pKa for the leaving groups and compare if you aren't confident.
>>
Nathaniel Shakewill - Sat, 11 Jul 2015 01:04:19 EST ID:h6BiFOLD No.76795 Ignore Report Quick Reply
Also I appreciate where you are going with this reaction haha. I approve.
>>
Bombastus !!HToBa9dh - Sat, 11 Jul 2015 15:09:14 EST ID:hNcgQxKK No.76797 Ignore Report Quick Reply
>>76794
Yupp. Looking at it again, my instincts agree with the methine/methylene bridge being stable. Even if it were to break, the OH- and Cl- should immediately react away to reform alumina and chloride ions (HCl should not be created due to it being too unstable to simply be formed in this reaction).
If you could make HCl this way, let me know. It'd be interesting to follow up on. But my guess is no.
>>
Doris Sunnersirk - Tue, 28 Jul 2015 13:10:32 EST ID:ykDmWZpt No.76854 Ignore Report Quick Reply
>>76797
>"Anydrous AlCl3 is a relatively strong Lewis acid. It bonds with the lone pairs of electrons on the oxygens in the ethers. When this complex is hydrolyzed, the ether is cleaved. When you do this to safrole, you can definately expect a mess, since the methylenedioxy ring gets cleaved, and things can get even more out of hand from there. In the case of eugenol, this cleavage is exactly what we're looking for."
https://www.erowid.org/archive/rhodium/chemistry/eugenol.mdma.html


Nakura #lolwatmox by Nakura !xMsGPnYjBI - Mon, 20 Jul 2015 16:22:19 EST ID:l2jFwqQE No.76828 Ignore Report Reply Quick Reply
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http://www.bloomberg.com/graphics/2015-whats-warming-the-world/
Interactive Climate Change Thing.
>>
Sophie Worthingwill - Tue, 21 Jul 2015 00:52:01 EST ID:YhREOUdy No.76829 Ignore Report Quick Reply
>climate deniers

So sick of the bull crap. A person would have to be completely delusional to think the climate is going to stand perfectly still. As if we live in a perfectly static artificial world, created just for us with unwaveringly perfect conditions? The term "climate denier" is so full of bias it could explode.

>well this NEW data from ~NASA~ (oooh) proves once and for all that the climate is changing

Yes, fine, the data shows the climate is changing as we swing from one ice age to the next. Alright already. Yeesh.

>and even though we can't ever prove it beyond a hilariously vague correlation, we just KNOW that it's caused by man so we need to buy carbon offsets and tax the living shit out of everyone who uses hydrocarbons and we need to elect these so-called social democrats who will bravely enact more laws and do something about-

Yeah no. Heard this little song and dance before, sweetheart. For the ten billionth time: It's not gonna work.
>>
trypto - Tue, 21 Jul 2015 09:09:57 EST ID:pDka/jle No.76830 Ignore Report Quick Reply
>>76829
I'm all-in on global warming. I think it's happening and we're responsible. I think governments should take action to cut back greenhouse gas emissions, invest in nuclear and renewables, and research geoengineering to control the climate.


But you're right about the coverage. 'climate deniers' is ridiculous, too many one-off studies are presented as proof (when they're not even newsworthy), and the financial instruments proposed are total scams.
>>
Alice Goodfoot - Tue, 21 Jul 2015 15:43:51 EST ID:JdiGsSqV No.76831 Ignore Report Quick Reply
>>76829
>People shitting on the west for our emissions.

Not realizing that even if the US and western Europe just went to another dimension, the rest of the world that is considered developing is just shitting on the planet and not giving a rat's ass.

Seriously even if the US went to something completely clean and Europe and Canada followed suit, the whole of everybody else would still be causing climate change.
>>
Caroline Gashhine - Sun, 26 Jul 2015 22:41:43 EST ID:uGD5aNS6 No.76851 Ignore Report Quick Reply
>>76829
>Yes, fine, the data shows the climate is changing as we swing from one ice age to the next.
You are ignoring rates man. These things typical occur at much slower rates than they are now, which implies something must be causing upsetting the balance and tilting the equilibrium in some way.

Even you have to admit that a reasonable logical deduction is that we are the cause. If CO2 is considered a major factor, and CO2 normally cycles yet is experiencing a dramatically increased rate of buildup, wouldn't it not be that far fetched that some sort of force is behind the acceleration? And since we do produce metric shit-tons of CO2, is it really that far-fetched that we are not the cause?


P-glycoprotein Efflux Transporters by WIAKR+Pa - Fri, 24 Jul 2015 02:05:30 EST ID:lfUESqVd No.76839 Ignore Report Reply Quick Reply
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Does anyone know why loperamide is so easily expelled after it has crossed the BBB when compared to, say, morphine or fentanyl? I vaguely remember reading somewhere that it was because of the chlorine atom, but that could be totally wrong.

I know that the diacetylation of morphine into heroin facilitates its crossing the BBB by making the molecule more nonpolar, but that doesn't explain why it isn't expelled by the P-glycoprotein.

I have a few links, and I've read the majority of them. The third one says removing electronegative atoms should decrease the efflux, so it seems that removing the chlorine would help.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401600/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3401598/
http://www.ncbi.nlm.nih.gov/pubmed/16686365/

Pic related. I don't want to be 'that guy' who wants to acetylate everything because that's what works for heroin, but if it works then it works. What other changes to the molecule might make this drug more recreational?
>>
WIAKR+Pa - Fri, 24 Jul 2015 03:57:47 EST ID:lfUESqVd No.76840 Ignore Report Quick Reply
1437724667091.png -(71438B / 69.76KB, 912x989) Thumbnail displayed, click image for full size.
>>76839
Whoops, I fucked up the third molecule. My bad, it's pretty late at night. Here it is fixed. Nb
>>
WIAKR+Pa - Fri, 24 Jul 2015 04:00:05 EST ID:lfUESqVd No.76841 Ignore Report Quick Reply
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>>76840
One last picture since apparently the OH can be acetylated as with morphine. Nb
>>
Caroline Gashhine - Sun, 26 Jul 2015 22:32:18 EST ID:uGD5aNS6 No.76850 Ignore Report Quick Reply
I'm not entirely sure, but do consider that heroin itself is just a prodrug for morphine. By that I mean heroin itself does not cause the affects but deacetylation of said molecule can then generate the affects.
I think 6-monoacetylmorphine has some effects, with 3-MAM not really producing much, and straight morphine having the most affect.

My point being that perhaps heroin can rapidly cross the BBB, both into and out of the brain, but a higher concentration of deacetylating enzymes inside the BBB that sort of "trap" the resulting morphine in the brain. My research advisor jokingly refers to the BBB as the Brain-Blood Barrier because we tend to forget it stops things from leaving the brain, too.

Purely conjecture/speculation, but perhaps Lope is not able to be chemically modified such that it can be trapped within the brain. Adding functional groups wouldn't necessarily remedy this, since the base molecule is already quite permeable?


Grow your own drug? by Esther Bezzlehid - Wed, 23 Apr 2014 23:03:20 EST ID:SneqK8/u No.74586 Ignore Report Reply Quick Reply
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Why do you think no one has tried to grow their own coca/poppies indoors? Just surprised since weed and shrooms have been cultivated indoors for quite a while now. Granted processing cocaine and (probably) heroine takes more work but still, hydroponics have become complex. So, I would reason that drug extraction from other plants doesn't seem too difficult for some of the more curious in the age of the internet.
>Anyway, why do you think this hasn't been tried yet?
31 posts and 4 images omitted. Click Reply to view.
>>
WIAKR+Pa - Thu, 23 Jul 2015 09:57:46 EST ID:lfUESqVd No.76834 Ignore Report Quick Reply
>>76820
Would supplementing their growth with l-tyrosine do anything? I couldn't find anything online and /crops/ is 99% how do I marijuana
>>
Bombastus !!HToBa9dh - Fri, 24 Jul 2015 17:14:39 EST ID:vbS8CtHn No.76842 Ignore Report Quick Reply
>>76834
Hey there, WIAKR+Pa. Nice to see you on /chem/ ^o^
I wouldn't know much about the l-tyrosine. As far as I know, the only thing that has been shown to noticeably increase alkaloid content is carbon dioxide. You may be able to stimulate growth by ramming metal blades across the lawn every week as they respond to stress and stuff but the thing is you can't really be sure.
Oh and also, water all opium poppies with soda water. Or make your own soda water by tossing a piece of dry ice in water in a thermos. I think they have home carbinators at walmart, too, though.
>>
WIAKR+Pa - Fri, 24 Jul 2015 18:47:39 EST ID:lfUESqVd No.76843 Ignore Report Quick Reply
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>>76842
Nice to be here Bombastus. They sell bulk tyrosine as a supplement, and it's used at a rate of 2mol tyrosine/1mol morphine in the biosynthetic pathway of the opium poppy, so I definitely get the feeling that if it can be reasonably absorbed by the plants then it should increase the alkaloid content. Maybe I'll do a little unofficial test with a few plants. Nothing huge, but if the chance arises then I'll see what I can do.
>>
Bombastus !!HToBa9dh - Fri, 24 Jul 2015 19:41:48 EST ID:vbS8CtHn No.76844 Ignore Report Quick Reply
>>76843
if i didn't fucking hate fucking botany with a fucking wrath, then i'd probably go around growing poppy plants and analysing the difference in morphine. you could always do that and report back?
i'm sure a lot of people would be quite greatfull for that. but my guesses (with my limited understanding of biosynthesis) is that just because you have a precursor doesn't mean you will get more end product

the complex pathway you posted up probably has a limiting reaction that isn't just the starting precursor. this is just me speaking for a statistical point of view. it could very well increase morphine production but i don't think it's likely
>>
Caroline Gashhine - Sun, 26 Jul 2015 22:24:26 EST ID:uGD5aNS6 No.76849 Ignore Report Quick Reply
>>76844
>just because you have a precursor doesn't mean you will get more end product
This, 1000X
enzyme kinetics are tricky because in a test tube you can force a reaction with high concentrations of substrate, but often enzymes are highly regulated, including inhibition by the products of the reaction or biosynthetic pathway.

Simple equilibrium dynamics and mass action, that sort of thing, doesn't really apply to biosynthetic pathways. It's worth a try though.


How many great grandparents do I have? by Eliza Brecklekedging - Thu, 23 Jul 2015 19:47:38 EST ID:AFCPP6XZ No.76836 Ignore Report Reply Quick Reply
File: 1437695258522.jpg -(21669B / 21.16KB, 480x327) Thumbnail displayed, click image for full size. 21669
Has anybody roughly calculated the number of generations separating us from the oldest known organisms?
>>
Nigel Bipperson - Thu, 23 Jul 2015 23:05:11 EST ID:pSzcCxpL No.76837 Ignore Report Quick Reply
>>76836
That would be impossible because we don't know all of our antecedents or their average generation times.
>>
Reuben Gongerwater - Sun, 26 Jul 2015 08:55:04 EST ID:pXaPdrMd No.76846 Ignore Report Quick Reply
>>76837
It would be impossible to get an exact number, but it would be only difficult to generate a reasonable approximation. It comes down to a matter of how many orders of magnitude off you might be.

I'm not into this evolutionary stuff, so I don't know the numbers BUT apparently there's 3.5 billion years between us and the first cell. Assume 1 hour generation time until 610 million years ago when multicellular organisms appear. Let's move on to a 10 hour generation time. Animals popped up pretty soon, so 600 million years ago the generation time jumped to 10 days. 500 million years ago things crawled on the land with, say, a 1 month generation time. Around 360 million years ago amphibians appears so let's go with a 6 month generation time for a seasonal sorta thing goin on. 150 million years ago amniotes appeared, so let's finally reach a 1 year generation. Mammals 130 million years, so jump up to 2 years. Homininae 10 million years ago; big jump to 15 years. Modern humans 250,000 years so 20 years.

Despite my pulling this out of my ass/wikipedia, let's do a tally:

1 hour generation time: 2.89 billion years * 8760 hours per year *1 gen/hr = 25.3 trillion generations
10 hour generation time: 10 million years * 8760 hours per year * 1 gen/10 hrs = 8.76 billion generations
10 day generation time: 100 million yr * 365 day/yr * 1gen/10day = 3.65 billion generations
1 month generation time: 140 million yr * 12 month/yr * 1 gen/month = 1.68 billion generations
6 mo. gen time: 210 million yr * 12mo./yr * 1 gen/6mo = 0.42 billion gen
1 yr gen time: 20 million yr = 20 million gen
2 yr gen time: 120 million yr = 60 million gen
15 yr gen time: 975000 yr = 650000 gen
Comment too long. Click here to view the full text.


alternatives to unattainable chemicals by Simon Sommlebark - Thu, 23 Jul 2015 17:20:43 EST ID:SazBGrfb No.76835 Ignore Report Reply Quick Reply
File: 1437686443314.jpg -(46380B / 45.29KB, 480x360) Thumbnail displayed, click image for full size. 46380
If one would like to do Kash's advaned lsa extraction but didnt have access to toluene or DCM, what could they use? lsa crystals would be ideal for that person imo.
>>
Nigel Bipperson - Thu, 23 Jul 2015 23:08:40 EST ID:pSzcCxpL No.76838 Ignore Report Quick Reply
>>76835
Toluene is readily available at hardware stores. You could also try xylene.
>>
Cedric Grandshit - Fri, 24 Jul 2015 21:29:39 EST ID:mEgh7QsF No.76845 Ignore Report Quick Reply
>>76835
dcm you can order from ebay (from europe but mine came through to canada)

and like the above dude said you can buy decently pure toluene at the hardware store


Toxic house by Charles Biddlechat - Sun, 19 Jul 2015 13:05:19 EST ID:WlN9uuNp No.76821 Ignore Report Reply Quick Reply
File: 1437325519844.jpg -(147030B / 143.58KB, 960x720) Thumbnail displayed, click image for full size. 147030
>live in 200 year old house
>window is 200 years old and made of wood
>live in climate where the wind is blowing 60 mph every single day
>wind comes in through my window 24/7
>the smell that comes from my window is musty and makes me sick

I'm pretty sure there is lead or something toxic in this window because I feel like shit every single day. There's paint chipping off it and the window isn't even sealed. What do?
3 posts omitted. Click Reply to view.
>>
Bombastus !!HToBa9dh - Sun, 19 Jul 2015 17:44:39 EST ID:vbS8CtHn No.76825 Ignore Report Quick Reply
>>76823
then cut out some wood and buy a window that fits the dimensions.
This is why I linked you to >>>/howto/. They'll have better ideas than me for replacing outdated windows as long as you have the house information.

Also, ask them how to remove mold.

>>76824
No; This is the basis of homeopathy, lol. I know you didn't want it to be but you've just proposed a homoeopathic toxin, lmao.
>>
Nicholas Turveygold - Sun, 19 Jul 2015 19:36:24 EST ID:pDka/jle No.76826 Ignore Report Quick Reply
>>76821
You made a thread about this before. Go to the doctor. If it's lead poisoning, then they will very easily be able to tell by a simple blood test. It's probably not the lead, though.
>>
Bombastus !!HToBa9dh - Mon, 20 Jul 2015 16:09:18 EST ID:ElYFdcKO No.76827 Ignore Report Quick Reply
>>76826
That's what I thought. But I don't think it's the same guy as kNWNBofZ in this post: >>76584

nb.
>>
Ebenezer Gummershit - Wed, 22 Jul 2015 15:21:56 EST ID:cM6rhCgJ No.76832 Ignore Report Quick Reply
Use an epoxy paint coating over the edges on the inside and the outside.
>>
Beatrice Bobberway - Wed, 22 Jul 2015 18:07:25 EST ID:t+gXfaEF No.76833 Ignore Report Quick Reply
>>76821
test


Kratom synthesis by Hedda Wonkinstock - Tue, 16 Jun 2015 09:24:38 EST ID:hBwYKLP1 No.76685 Ignore Report Reply Quick Reply
File: 1434461078212.jpg -(158360B / 154.65KB, 900x776) Thumbnail displayed, click image for full size. 158360
hello chem/ im a complete noob to chemistry but i have been thinking if there is any way to synthesize kratom alkaloids to make a more powerful "drug"?
I read somwhere scientists were making a replacement for opiate drugs using kratom
3 posts omitted. Click Reply to view.
>>
Shitting Dunnercocke - Wed, 17 Jun 2015 22:14:32 EST ID:0FJPg3OJ No.76692 Ignore Report Quick Reply
>>76690

Nobody has any chance of doing that without access to a full lab, chiral resolution techniques, it has 5 chiral centers FFS, 32 potential isomers, fuck that.

If you can synthesize that, you might as well just make a fuck ton of LSD or a synthetic opiate like a fentanyl derivative because you are a fucking amazing chemist and apparently, very well equipped for organic synthesis.

Its already synthesized for you in kratom, its much easier to design an extraction to isolate the active/actives from kratom than it is to synthesize kratom from serotonin.
>>
Bombastus !!HToBa9dh - Thu, 18 Jun 2015 12:48:40 EST ID:qb2qUOr3 No.76695 Ignore Report Quick Reply
>>76692
Hey! I was just offering a glimmer of help.

As I mentioned above: " It won't be buttfuck impossible! It'll just be incredibly hard." Eluding to its nature of still being incredibly hard.
>>
Shitting Dunnercocke - Thu, 18 Jun 2015 17:19:18 EST ID:0FJPg3OJ No.76696 Ignore Report Quick Reply
>>76695

Incredibly hard is realistically impossible in this case, lets be practical. We're talking kitchen chemistry not a full lab situation.
>>
Hugh Fanwater - Thu, 16 Jul 2015 09:09:07 EST ID:WoOdvzFR No.76817 Ignore Report Quick Reply
>>76685
total noob in this field but would an alkaloid extraction be possible with sodium carbonate/bicarbonate and a solvent like alcohol or acetone for fast evaporation?
>>
Samuel Clodgetat - Thu, 16 Jul 2015 17:33:18 EST ID:mEgh7QsF No.76818 Ignore Report Quick Reply
>>76817

7-hydroxymitragynine and mitragynine are both water soluble and likely soluble in ethanol aswell. you could try making "tea" with ethanol and evaporating it to yield some alkaloids.

i have literally zero experience with kratom though i could be wrong


Animal with endocrine system most similar to humans by Eliza Hicklegold - Wed, 15 Jul 2015 19:19:10 EST ID:AhXCC5C1 No.76813 Ignore Report Reply Quick Reply
File: 1437002350318.jpg -(28138B / 27.48KB, 480x347) Thumbnail displayed, click image for full size. 28138
Doing a 4k report on addiciton, just need some confirmation so I can use certain sources

Is it white lab rats like my initial thought is, or is it something else. I know ferrets have a similar immune system to ours...
>>
Thomas Doddleman - Wed, 15 Jul 2015 20:39:32 EST ID:pSzcCxpL No.76815 Ignore Report Quick Reply
>>76813
Here's a journal article titled "Animal Models of Substance Abuse and Addiction: Implications for Science, Animal Welfare, and Society" to help you, and a relevant quote from the 5th-ish paragraph of the article.
>Although rodents are most often used in these studies, this model has been used with a variety of species including nonhuman primates, dogs, and cats.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890392/

LITERALLY THE FIRST GOOGLE RESULT FOR "addiction research animals". What the fuck, man? Seriously. What the fuck?
>>
Walter Songerford - Wed, 15 Jul 2015 21:11:07 EST ID:AhXCC5C1 No.76816 Ignore Report Quick Reply
>>76815
thankyou, thankyou, thankyou!

The report is on the human aspects of successful treatment in terms of subsequent relapse, so i hadn't geared my head to think about it in terms of organisms other than humans

I am sorry, it's been a long day and i'm pretty beat. I'll brain harder from here on


Color Differences in Dansylation by Shit Clandlestutch - Wed, 15 Jul 2015 16:16:23 EST ID:6U9qqpUA No.76808 Ignore Report Reply Quick Reply
File: 1436991383212.jpg -(166917B / 163.00KB, 750x600) Thumbnail displayed, click image for full size. 166917
So, during my lab's standard dansylation protocol (for wheat, in this case) , I have found that the colors in each microtube vary. I don't know if this is because each tube contains a different genotype of wheat, or if the process isn't thorough enough to get the dansyl chloride mixed up in the tube to produce more yellow color. I don't know if that will have an effect on the results when I run the samples through HPLC at the end, but thought I'd ask.


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