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Purifying and Freebasing by William Sinningworth - Sun, 16 Oct 2016 02:30:25 EST ID:zsw9I8fO No.78302 Ignore Report Reply Quick Reply
File: 1476599425480.jpg -(16063B / 15.69KB, 369x305) Thumbnail displayed, click image for full size. 16063
1)
I've gone through this process to convert salts -> freebase by:
adding some salt drug to a lye solution then using hexane to pull the freebase and evaporate.
My question is: while this process seems to have to have worked with a 2C and with U-44770, can you think of any case where the NaOH will mess up the drug somehow? Or a case where the freebase won't dissolve in the Hexane?

2) Is acetone good enough for purifying most drugs? How are you even supposed to know the solubility of a lot of these new drugs like 4-methyl-pentedrone or 3-Fluorophenmetrazine? Acetone is used for MDMA and Ketamine purificaiton, so what stuff does it NOT work on?
6 posts omitted. Click Reply to view.
>>
Press !QUHukXEvkY - Fri, 11 Nov 2016 13:45:49 EST ID:JeMHyPDO No.78339 Ignore Report Quick Reply
>>78338
Im not sure if sodium hydroxide would be okay.
You could make some Na2CO3 by heating NaHCO3
>>
Bombastus !uYErosQbLM!!Mybq1UbK - Tue, 15 Nov 2016 01:08:30 EST ID:6N1t5rKu No.78346 Ignore Report Quick Reply
>>78339
BAKING SODA I GOT BAKING SODA
>>
David Suckleson - Tue, 22 Nov 2016 19:07:24 EST ID:zsw9I8fO No.78358 Ignore Report Quick Reply
>>78339
So Na2CO3 is a better base than NaHCO3?
>>
Cyril Chittingbare - Tue, 22 Nov 2016 22:17:00 EST ID:Q2W2CR89 No.78359 Ignore Report Quick Reply
>>78358
Yes. CO3^2- is a better base than HCO3^- since it is able to accept 2 protons as opposed to 1. Not sure if OP should use a strong base like NaOH tho..
>>
Bombastus !uYErosQbLM!!Mybq1UbK - Fri, 25 Nov 2016 23:22:49 EST ID:sglEgUGb No.78370 Ignore Report Quick Reply
>>78359
That doesn't determine strength.

Hydrochloric Acid is around 3000x times stronger than the first proton of phosphoric acid despite it only having one proton.


Help please!! by LaDiDotty - Mon, 21 Nov 2016 04:54:04 EST ID:xxe0PbAv No.78353 Ignore Report Reply Quick Reply
File: 1479722044179.jpg -(187340B / 182.95KB, 374x500) Thumbnail displayed, click image for full size. 187340
Hi all,

I hope I'm asking this in the best spot & really hoping someone can assist me w/this......

So I'm getting ready to try ULDN for the 1st time, that is if I can get this figured out. So I thought I added my 50mg tab of naltrexone to 1 liter or 1000mls of water however I didn't look close enough at the bottle I'm using, duh I know. Anyhow instead of 1 liter the bottle I added everything into is 1.25L.
So I'm trying to figure out how many mcg's I have per ml. The recipe I followed has the dosages based on 1 ltr not 1.25 ltr. Considering this is touchy & the dose is based on mcg's I wanted to verify what I now have w/some folks that are way better in the chemistry & mixing department.
I would be very grateful for any info you may be able to provide. Anything you also may like to add about ULDN would also be greatly appreciated.

Thank you!
>>
Press - Tue, 22 Nov 2016 18:45:48 EST ID:lyRi8w2C No.78357 Ignore Report Quick Reply
Your solution contains 0.04mg per mL or 40microg per mL

But i doubt that the volume of your bottle was very accurate.

Isnt the solution going to perish? Depending on the pill contents it might spoil quickly
>>
LaDiDotty - Tue, 22 Nov 2016 22:22:41 EST ID:xxe0PbAv No.78360 Ignore Report Quick Reply
>>78357
Thanks for your reply. I don't know how fast it will perish. I've read that w/refrigeration it can last a month or 2. Just have to make sure I order more long before I run out. I think I'll try cutting the next tab in half & mixing it w/ 1/2 the amount of water. I know it's only been less than 48hrs but so far this is amazing. I wasn't exactly sure how much I diluted the recipe I followed down so based on the original directions I've just been using 5-7 drops w/each dose of opi's. The analgesia & duration of how long they last is pretty amazing. I wish more people talked about this.
Anyhow thank you so much for replying, it is greatly appreciated.

Happy, almost, Thanksgiving.
>>
press - Wed, 23 Nov 2016 07:56:56 EST ID:JRoOF8iS No.78364 Ignore Report Quick Reply
>>78360
you might want to either get a volumetric flask, which might get expensive i dunno, or find a bottle with which you can very accurately measure a set volume. ideally it would be a bottle with a very thin neck, which would be filled to a certain level of the neck

if your solution is really mixed and the naltrexone is readily water soluble you could store it in several small containers while frozen. then youd simply have to take out a single container, thaw it and shake it before use while the others still remain frozen.

any idea how big one of your drops is? or how much one drop weighs?
>>
LaDiDotty - Thu, 24 Nov 2016 14:24:51 EST ID:xxe0PbAv No.78366 Ignore Report Quick Reply
>>78364
Hi!

I don't have any fancy measuring bottles, can you suggest somewhere I could find one in expensively? The recipe I'm following is to mix 1 50mg tab into 1L but it makes a huge amount. I was thinking to see if I could cut a tab in half or even quarters, cut the water down accordingly but I'm afraid of possibly not cutting it perfectly in half or quarters each time. Your idea of storing in the freezer is great! I was afraid the solution would go bad before I'd ever get thru an entire liter. Even though the naltrexone tabs were easy enough to get I'd prefer not to waste them. I found it odd that w/each study or recipe I found nobody talked about properly storing the mixture or preserving it aside from putting the mix in an amber or cobalt glass bottle or storing in the fridge.
Do you think freezing the mixture would degrade it in any way? Do you know if the mixture is sensitive to light?
I did get a couple different syringes from the pharmacy, 1 I think is useless for dosing anyways, it's more of a child's medicine dropper, 5mls w/o small enough increments for dosing, maybe good for something else. The other syringe is 1ml, has .10 increments & even smaller. I just tried counting how many drops a full ml holds & came up w/30 almost 31 drops. One study & recipe I read said their 1ml dropper held a perfect 20 drops. Not sure what they're using but I tried several times & came to 30-31 each time.
With the recipe I'm following it says that what I should end up with is 50mcg per 1ml & .2 ml = 10mcg. Because I accidentally didn't see the bottle I'm using is a 1.25L instead of a 1 L my drops are slightly diluted. I found a couple other recipes but they're all relatively the same.
The naltrexone tabs I got dissolve very fast & completely in water. One recipe said not to shake the tab in the bottle, that made no sense to me since you want to make sure you have even doses. Another recipe said to shake it vigorously, I did the latter. When I dropped the tab in the water I just left it to dissolve while I ate dinner. When I came back it had totally dissolved on its own w/just an uber tiny amount of p…
Comment too long. Click here to view the full text.
>>
press - Thu, 24 Nov 2016 15:41:24 EST ID:tXprf7n7 No.78367 Ignore Report Quick Reply
>>78366
id try ebay or amazon for chinese volumetric flasks. doesnt matter wether its a plastic one or one made from glass aslong as the mergin of error is tight enough. real men use glass, because theyre not afraid of suffering the pain of fucking up.

a volumetric flask should be cheaper than a really accurate scale. how accurate is yours?

i dont really see how using amber or colbalt glass bottles would help, those are normally used for light sensitive stuff but im not sure about naltrexone being light insensitive. my bet would be that it shouldnt be, since ive never heard of morphine or oxymorphone are. its not going to degrade when its frozen, but be sure to really give it a good shake after dethawing it. use plastic bottles for storing it frozen. ive seen quite a few phds fucking that up once in a while.

for measuring the final dose a syringe is good
the size of a drop also depends of the diameter of the opening so its not a suprise they found some other ratio. i have no idea about ultra low naltrexone, once read that it can reap lotsa benefits but i dont remember the dosage tl;dr cant get lantrexone anyways

i guess the particulate is some gunk like magnesium stearate or some other stuff they put in to make the pill super duper
no biggie, you have a nice one too


Chemical reaction simulator by Martin Dartfoot - Tue, 15 Nov 2016 15:24:42 EST ID:Ul4obZPS No.78349 Ignore Report Reply Quick Reply
File: 1479241482322.png -(202713B / 197.96KB, 1312x782) Thumbnail displayed, click image for full size. 202713
Do you know about any program that can be used to simulate chemical reactions?
What is your opinion about it? I recently stumbled upon "Cain" but still haven't learn to work with it.


Boron tribromide demethylation of codeine by Jarvis Hinnerforth - Mon, 10 Oct 2016 14:55:50 EST ID:9Opqdgsf No.78280 Ignore Report Reply Quick Reply
File: 1476125750712.png -(19996B / 19.53KB, 593x246) Thumbnail displayed, click image for full size. 19996
I am having trouble with this synthesis. I take 15ml DCM with 200mg codeine base dissolved and make sure its really dry with sieves. Then add something like 500mg of boron tribromide. Immediately the codeine drops out of the DCM solution... no doubt my homemade BBr3 contains a small amount of HBr and Br2. This stuff is unbelievably reactive with air, i've never seen anything fume like it in my life. So i waited/stirred 30mins then added ice/ammonia. No precipitate, i assume the codeine hbr simply dissolved in the aqueous. So next i tried the same thing but added 200mg DIPEA to soak up the acid. Still no morphine precipitate. I worked up both layers both times and verified there was no morphine, i thought it might be dissolved in the high PH aqueous layer but that's only possible with NaOH i believe, morphine should always be insoluble in ammonia hydroxide. I don't know what the problem is.

My boron tribromide is a bit red, i don't have enough to distill. I started from Br2 and Al to make aluminum bromide, anhydrous. Unfortunately i couldn't distill this either but i did leave it under vacuum to hopeful get the free bromine out. I melted it and poured it into another flask with potassium tetrafluoroborate and ended up with only a few ml of BBr3 distilling over. Next time i will use liquid tetrafluoroborate. All 3 of these things really fume like hell. I'm not looking forward to doing it again. I will try to use a vacuum next time, my joints weren't greased and it was pulling in more air then it was worth. I have to make sure i don't get the aluminum bromide on the ground joints as well, god damn what a mess. A propane torch wouldn't even get them apart i had to soak in WD40 then use a propane torch.
28 posts and 4 images omitted. Click Reply to view.
>>
press !QUHukXEvkY - Fri, 21 Oct 2016 14:50:08 EST ID:B3jdPBiB No.78320 Ignore Report Quick Reply
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>>78315
while im already derailing a thread; do you have any ideas on muhsroom extraction?
havent attempted it yet since the hooch is still in the mail but i was going to go with the very crude method of soaking the raw material in ethanol w=0,7 and then letting the filtrate evaporate in order to get material that i might recrystallize.
i suspect that simply soaking the material in dilute acetic acid and then basifying it with a subsequent non polar extraction (maybe DCM, maybe EtOAc)
but the zwitter ionic nature of psilocin bugs me to no end

i have to salute OP's resources
i might be able to contribute on the matter once i stop being this high lol

its pretty sad how little happens on /chem/, sciencemadness is ice but theyre all very catious (rightfully so) eventhough i saw several of their mods in the hive or the successors of it
>>
Charlotte Fuckingville - Sat, 22 Oct 2016 00:27:23 EST ID:9Opqdgsf No.78322 Ignore Report Quick Reply
The codeine was is from 8mg tablets, 15mg caffeine, 200mg aspirin. Lots of other filler and shit on the ingredient list. I was thinking the caffeine should have been washed away by my DCM wash (while the codeine was still in phosphate form). So idk. Yes chromatography is likely the answer, i've never run a column but i suppose i can figure it out.

I have a UV bulb but i need to find a power supply and ballast, i forget what is required now. Something like 20 volts and a 100 ohm resistor. Its one of those really small uvc germicidal bulbs off ebay, screws into something like a Christmas light socket. Obviously 120ac would blow it though, even 12 volts ended up blowing it because once the mercury heats up and vaporizes it causes a huge current spike which must be limited by some kind of ballast.
>>
Charlotte Fuckingville - Sat, 22 Oct 2016 00:48:34 EST ID:9Opqdgsf No.78323 Ignore Report Quick Reply
>>78320
I used to grow shrooms i thought about extraction but never attempted it. I was planning to use methanol only because its cheap and available at the hardware store. Evaporate with minimal heat (enough to keep condensation from making a wet goop mess) and a fan. Then try to wash with petroleum ether, maybe recrystallize from methanol in the freezer. Maybe add a little dcm to lower the solubility in the mixture.

Your way would probably be cleaner and higher yielding, but who knows. According to this somthing like that should work. https://erowid.org/archive/rhodium/chemistry/psilocin.extraction.html

I hate water in these situations though, so hard to evaporate without heat or time.
>>
Esther Donderkare - Mon, 24 Oct 2016 19:43:12 EST ID:2Hc2eoG6 No.78327 Ignore Report Quick Reply
Would it be easier to just buy some CYP2D6...
>>
Albert Henkinbanks - Wed, 26 Oct 2016 15:27:19 EST ID:9Opqdgsf No.78328 Ignore Report Quick Reply
>>78327
I don't think it would be feasible to create an artificial liver, but i really don't know. I do know scientists have modified e.coli to produce thebaine. 2mg from 20grams of sugar isn't too good though, and i expect the modified bacteria would be incredibly fragile. So unfortunately we won't be growing morphine in mason jars like magic mushrooms anytime soon.

Countries like Canada are lucky just to have codeine. If you don't have an opiate to start from you are pretty much forced to grow poppies.

I've found my mercury, i'm going to shake the small amount of bbr3 i have left with it then try the reaction again.


Piperadone by Rebecca Ginningman - Sun, 23 Oct 2016 05:29:48 EST ID:9Opqdgsf No.78324 Ignore Report Reply Quick Reply
File: 1477214988518.png -(19315B / 18.86KB, 203x200) Thumbnail displayed, click image for full size. 19315
Any ideas how to synthesize 4-piperidone?
>>
Eugene Dabblekat - Sun, 23 Oct 2016 22:53:02 EST ID:9Opqdgsf No.78326 Ignore Report Quick Reply
OP here again. Tried the dickmann condensation, acrylates are too hard to make and the burnt plastic smell is not tolerable. The mannich seems to only like to make piperadones substituted on the 2&6 (benzaldehyde, acetaldehyde). Although i havn't tried it yet formaldehyde might work with acetonedicarboxylate, hydrolyse and decarboxilate to 4-piperadone. I can tell you it doesn't work with phenethylamine not in water, alchohol, or acetic acid. Not nearly as easy as most of the internet would have you believe, its quite the opposite. Unless its just me, which is possible as well.

Maybe posassium cyanide + epichlorohydrin = 3-hydroxyglutaronitrile. ***Journal of the Chemical Society, , p. 1164,1166 = 4-hydroxypiperidine**** Then oxidize the 4-hydroxypiperidine alcohol to a ketone somehow. Maybe react with phenethylbromide first then the amine is protected.

Or any other possible routes? I'd love to hear it.


Anhydrous AlCl3 by Walter Claggleville - Fri, 29 Jul 2016 15:16:32 EST ID:ykDmWZpt No.78112 Ignore Report Reply Quick Reply
File: 1469819792455.png -(15045B / 14.69KB, 300x251) Thumbnail displayed, click image for full size. 15045
Hello, chem!
Sorry if this is a stupid question, but here it goes:
I have aluminum (III) chloride hexahydrate but I need it in the anhydrous form.
Can I oven-dry it at ~100ºC?
Thanks in advance!!
20 posts and 2 images omitted. Click Reply to view.
>>
Nigel Sinderforth - Wed, 14 Sep 2016 17:44:05 EST ID:Ng8fVE40 No.78239 Ignore Report Quick Reply
test
>>
Shit Tillinggold - Thu, 15 Sep 2016 01:08:08 EST ID:zsw9I8fO No.78240 Ignore Report Quick Reply
>>78239
bad
>>
John Merringbury - Fri, 07 Oct 2016 23:06:18 EST ID:hBAZGxou No.78277 Ignore Report Quick Reply
You can demethylate guaiacols by a radical mechanism using CuSO4 + ascorbic acid. Don't waste your time with AlCl3.
>>
Betsy Pittwill - Mon, 10 Oct 2016 23:37:31 EST ID:yvh9Qry5 No.78285 Ignore Report Quick Reply
>>78277 got a ref for that?
>>
Esther Nossleway - Sun, 23 Oct 2016 22:30:30 EST ID:NIATBazO No.78325 Ignore Report Quick Reply
1477276230830.jpg -(9699B / 9.47KB, 224x287) Thumbnail displayed, click image for full size.
>>78112
mind if I ask you why would you want AlCl3? just wondering


>>78113
>>78120
bombastus and press are fucking bosses, I've learnt a lot with this guys

love you all


Freebase vs Salt Vaporize by Nathaniel Worthingfoot - Sat, 10 Sep 2016 00:01:05 EST ID:zsw9I8fO No.78226 Ignore Report Reply Quick Reply
File: 1473480065769.jpg -(324209B / 316.61KB, 503x376) Thumbnail displayed, click image for full size. 324209
Two questions
1) What's the reason that freebase drugs are preferred for vaporizing/smoking instead of salts?

2) Will lye and baking soda both freebase a drug the same? I'm guessing it just requires more baking soda because it's a weaker base?
16 posts and 1 images omitted. Click Reply to view.
>>
Edward Nottingpock - Sun, 02 Oct 2016 06:17:06 EST ID:ZcMU69D7 No.78269 Ignore Report Quick Reply
>>78233
When you evaporate a solution of HCl water the water evaporates and the HCl goes back into the gas phase leaving behind any salts you may have formed.
The problem is that it's just hard to get rid of all the water without leaving a hydrate or some moisture sticking around. You can try drying in the presence of a desiccant like NaOH
>>
Bombastus !uYErosQbLM!!Mybq1UbK - Thu, 06 Oct 2016 02:40:38 EST ID:Req4jw5M No.78274 Ignore Report Quick Reply
>>78269
>hard to dry
>hydrates
Normally true. However. When it comes to opiates. Not really.
>>
Doris Fomblefuck - Thu, 06 Oct 2016 13:08:35 EST ID:QFXcUDR6 No.78276 Ignore Report Quick Reply
>>78269
Okay great so that's what I was originally asking. You can make the pH of the solution acidic enough to convert all of it, then simply let it evaporate and you should have 1:1 mole of drug:salt. No need for a selective solvent to separate the drug:salt from excess acid and water.
>>
Albert Wiffington - Thu, 20 Oct 2016 12:58:49 EST ID:/9+sroAe No.78317 Ignore Report Quick Reply
>What's the reason that freebase drugs are preferred for vaporizing/smoking instead of salts?

Because most people don't have vaporizers that can heat up to 3000 degrees Fahrenheit.
>>
Clara Blythegold - Fri, 21 Oct 2016 18:17:20 EST ID:zsw9I8fO No.78321 Ignore Report Quick Reply
>>78317
Then why do people vape Methamphetamine HCl all the time?


the ratman 666 by Cornelius Fogglehedge - Mon, 17 Oct 2016 00:58:05 EST ID:95U922wa No.78303 Ignore Report Reply Quick Reply
File: 1476680285961.jpg -(57268B / 55.93KB, 577x551) Thumbnail displayed, click image for full size. 57268
>landlord comes to inspect clandestine meth lab property
>she notices the smell of benzaldehyde and asks what air freshener i'm using
>'almond breeze'
>>
Emma Widgetore - Thu, 20 Oct 2016 15:26:27 EST ID:thDqQFXE No.78318 Ignore Report Quick Reply
1476991587345.png -(1840399B / 1.76MB, 7528x5000) Thumbnail displayed, click image for full size.
top kek


Convert Codeine Pills (Just Codeine) by Nathaniel Worthingfoot - Fri, 09 Sep 2016 23:56:07 EST ID:zsw9I8fO No.78225 Ignore Report Reply Quick Reply
File: 1473479767769.jpg -(110887B / 108.29KB, 407x634) Thumbnail displayed, click image for full size. 110887
What would be the best way to get that methyl group offa there?
Well I don't really require morphine, but just whatever opioid is easiest to convert it to while also being smokeable/snortable/get-me-high-rush?
>>
Augustus Mimmlestine - Sun, 11 Sep 2016 16:54:42 EST ID:zsw9I8fO No.78230 Ignore Report Quick Reply
https://erowid.org/archive/rhodium/chemistry/hydrocodone.html
and here's the paper of that: https://www.dropbox.com/s/khn6dc88btaoeyf/A%20Rapid%20Nearly%20Quantitative%20Conversion%20of%20Codeine%20to%20Hydrocodone.pdf?dl=0

So how feasible is it to do this in your kitchen with chemicals bought from ebay? How available are these chemicals even?

Do we even have good forums available like Rhodium anymore? Sciencemadness doesnt like drug synthesis.
>>
Lillian Fellykudge - Wed, 12 Oct 2016 01:51:03 EST ID:zsw9I8fO No.78293 Ignore Report Quick Reply
>>78230
>first step
>"Parr hydrogenator jar,"
>nope

Why the fuck is it so hard to do anything with fucking codeine, fuck. I'll just IV it.
>>
press - Wed, 12 Oct 2016 04:26:18 EST ID:KOKj6dOY No.78294 Ignore Report Quick Reply
1476260778343.gif -(341552B / 333.55KB, 266x150) Thumbnail displayed, click image for full size.
make some hydrocodone. Pd/C and a mineral acid in ethanol and perhaps sone means of TLC to check conversion
>>
Bombastus !uYErosQbLM!!Mybq1UbK - Thu, 13 Oct 2016 11:28:23 EST ID:Req4jw5M No.78297 Ignore Report Quick Reply
>>78294
hey where you been

nb
>>
Press !QUHukXEvkY - Wed, 19 Oct 2016 02:10:48 EST ID:NyrybZOd No.78311 Ignore Report Quick Reply
>>78297
Was in a workplace accident, spent a week in the hospital
Was on sick leave for five weeks during which i invested my time solely into mushroom cultivation. Tfw no tyramine
Quit a job, took two new jobs. Nb


VR tech by Beatrice Faffingson - Tue, 20 Sep 2016 11:59:28 EST ID:TAs+XH9Z No.78259 Ignore Report Reply Quick Reply
File: 1474387168486.jpg -(252727B / 246.80KB, 1920x1080) Thumbnail displayed, click image for full size. 252727
with all the VR tech coming out
i wonder what scientific applications it will have.. not only for humans but even for animals

do you think it would be possible to suit a dog with a VR tech and simulate it as another species or put other data into its eyes/mind?
>>
Bombastus !uYErosQbLM!!Mybq1UbK - Thu, 06 Oct 2016 02:42:09 EST ID:Req4jw5M No.78275 Ignore Report Quick Reply
>>78259
Not really due to the issue of their perception, senses outside of the "normal five", memory, critical thinking, sight, etc.
For that, we'll need better brain mapping technology like how we saw a blurry image of what a cat saw on a screen once.
>>
William Bundock - Sun, 09 Oct 2016 23:58:56 EST ID:qtUm3Qxz No.78279 Ignore Report Quick Reply
>>78259

It will be the only handle the amount of information when piloting a Gundam.


Nootropics Textbooks/ Papers/ Literature by He - Thu, 22 Sep 2016 08:55:08 EST ID:XgflcvVv No.78260 Ignore Report Reply Quick Reply
File: 1474548908633.gif -(1268363B / 1.21MB, 310x314) Thumbnail displayed, click image for full size. 1268363
I'm looking for some textbooks/ literature on nootropics. My boss's brother is a surgeon, and he's heard rumblings from his pharmaceutical friends that there are compounds out there that aren't known to the public, and only given to people like special forces.

I think they're fascinating, and I'd love to better understand their chemistry. While most of my work in the industry has been with things like coatings and adhesives, I'm sure I wouldn't have any trouble with technical stuff, as I took plenty of high level organic classes in college.


C-F Bond Vaporize Harmful? by David Fanwater - Sat, 17 Sep 2016 21:44:07 EST ID:zsw9I8fO No.78254 Ignore Report Reply Quick Reply
File: 1474163047120.jpg -(9366B / 9.15KB, 297x238) Thumbnail displayed, click image for full size. 9366
Drugs with that Flourine-Carbon bond, although scary, are supposedly actually safe because the C-F bond is one of the strongest there can be, so not likely to metabolize into free flourine.

So with drugs like 4-FA, 2F-Ketamine, what if we vaporize them? Is a lot of heat enough to break that bond?
>>
Bombastus !uYErosQbLM!!Mybq1UbK - Sun, 18 Sep 2016 03:02:41 EST ID:Req4jw5M No.78255 Ignore Report Quick Reply
1474182161052.jpg -(33720B / 32.93KB, 337x390) Thumbnail displayed, click image for full size.
>>78254
lmfao. i find you cute.
you just stated that C-F bonds are one of the strongest bonds and then asked if heat will degrade it. I know for non-chemistry people, it's hard to put two and two together but I like how you are using your noggin, though. You're already better than three quarters of the students I've TAd.

Anyway, C-F bonds have a bond strength of 550kJ/mol where as regular methyl C-CH3 bonds have a bond strength of around 450kJ/mol. This really means that it's almost impossible to break this bond unless you have a self-feeding reaction like setting it on fire. But even then, the C-C bonds and C-H bonds would burn before the C-F bonds do
You'll be fine vaporizing whatever you legal substances you're sublimating for science, ofc.
>>
Bombastus !uYErosQbLM!!Mybq1UbK - Sun, 18 Sep 2016 03:04:54 EST ID:Req4jw5M No.78256 Ignore Report Quick Reply
>>78254
Also, is that face reaction from the comic where a guy gets high, walks over to the garbage can with a ziplock bag and his bong, drops the bong in the garbage can with a shattering sound, and then proceed to make that face?

Can't find it right now since I'm on mobile.
>>
David Fanwater - Sun, 18 Sep 2016 04:15:54 EST ID:zsw9I8fO No.78257 Ignore Report Quick Reply
>>78256
Yes lol, I cropped it from that.

So cool, there is some quantitative way to figure out what it takes to break a bond.

Break a bond... break a bong... pic related.
>>
Bombastus !uYErosQbLM!!Mybq1UbK - Sun, 18 Sep 2016 17:40:24 EST ID:4ppVjZXo No.78258 Ignore Report Quick Reply
>>78257
Bonds boil down to the electron configuration of the atoms they are bonded to (along with the neighbouring electrons) and the spatial organization of the bonds and atoms in the molecule.
To figure out the spatial organization, you just use your eyes and bond energy tables. To figure out electronical (relating to electrons) configuration, use the DFT program I told people about (http://boards.420chan.org/chem/res/77990.php) and play around with the orbital energy levels.


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