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Purity Testing GCMS HPLC etc Question by breakabond - Tue, 28 Feb 2017 08:07:46 EST ID:LObRvGV/ No.78584 Ignore Report Reply Quick Reply
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This is an email I sent out, but feel free to take a whack at it.

From the given information on the FAQ:
>Then we perform a qualitative analysis on each component identified where possible,
>comparing each substance with a pure reference standard.
>Our results directly provide the result of the salt of the substance, as we’re
>using a salt as a reference standard. The quantitative results are provided using
>a calibration curve from a reference standard.

as well as the techniques listed here https://energycontrol-international.org/drug-testing-service
It seems that almost all of those techniques can be used to generate a quantitative purity result, e.g. GCMS, LCMS, HPLC, UV/Vis.

So can you try to fill in the blanks here for me?

Generate pure quantitative result based on reference standard.
Comment too long. Click here to view the full text.
3 posts omitted. Click Reply to view.
breakabond - Sun, 05 Mar 2017 13:10:32 EST ID:LObRvGV/ No.78591 Ignore Report Quick Reply
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Its energycontrol, they charge 60 for % then $80 for pdf report (like wtf man9
trypto - Mon, 06 Mar 2017 00:52:16 EST ID:ltcKYWSL No.78592 Ignore Report Quick Reply
That sucks. So it's drugs made from a lab that's not trustworthy, and totally opaque... tested by a lab that a bit trustworthy and a bit translucent... Inconsistency is inevitable.

Vehk !7HYGxe5v5c - Wed, 15 Mar 2017 22:49:59 EST ID:l5Akm3J6 No.78601 Ignore Report Quick Reply

The compound in the bottom right is incorrectly labelled. The compound pictured is methadone, while it is labelled as methedrone, which is a methcathinone and related to mephedrone.

Step up, fam.
Walter Goodwater - Thu, 16 Mar 2017 21:31:37 EST ID:ZUVcy1Vx No.78607 Ignore Report Quick Reply
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A reference standard is a documented, authentic sample of the chemical you are looking to analyse for.

You dilute the reference standard in solvent at a range of concentrations, generally 5 different conc. are used for a good calibration curve.

You set up the instrument (GC/MS/HPLC/UV ect.) and inject each of those 5 standards you prepared.

The plot of detector response (peak area) as a function of each standard concentration should be roughly linear, fit a least squares line and use the equation of that line to calculate the amount of analyte in your test sample based on the peak area it gives.
Walter Goodwater - Thu, 16 Mar 2017 21:34:39 EST ID:ZUVcy1Vx No.78608 Ignore Report Quick Reply

this process is not nearly as simple as it sounds.

if you really want to test the lab's accuracy weight out a decent sized sample of a compound (~500 mg) and grind it well, then submit two samples of the same grind. They should be within 10% or so of each other

How to creat Oxygen (O2) by Commander Preppy - Fri, 27 Jan 2017 13:36:17 EST ID:MuFe+5ez No.78510 Ignore Report Reply Quick Reply
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Let's say you're in Syria in an ai-tight room and there's poison gas detonated. What simple household materials could you use to synthesize oxygen? Is it possible to use rust as a source for instance?
3 posts omitted. Click Reply to view.
Press - Tue, 14 Feb 2017 15:49:20 EST ID:9DUR15Uh No.78529 Ignore Report Quick Reply
We have a winner.
Acaelus - Wed, 15 Feb 2017 01:33:18 EST ID:vl5gPJeC No.78531 Ignore Report Quick Reply
Its called eletrolysis
Nicholas Biggleforth - Thu, 16 Feb 2017 08:48:55 EST ID:WYa1y06F No.78535 Ignore Report Quick Reply
Wouldn't that just end in you dying from oxygen poisoning?
Hugh Trotspear - Tue, 07 Mar 2017 11:46:56 EST ID:Lx3qHXrW No.78595 Ignore Report Quick Reply
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Get some dry D cells. Take out the magnesium dioxide
Get some Hydrogen Peroxide
Capture the bubbles
Green Fox - Thu, 16 Mar 2017 02:06:12 EST ID:7S/32W3t No.78602 Ignore Report Quick Reply

You mean manganese dioxide.

The most dangerous weapon in the world, hiding in plain sight. by Graham Wellypat - Fri, 10 Mar 2017 20:09:22 EST ID:zYI/8bOR No.78598 Ignore Report Reply Quick Reply
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This is not a drill.
>cell phone towers are weaponized death rays ready to nuke the planet or act collectively as a super powerful HAARP-like machine.
>Orgonite converts harmful rays into healthful ones, and can be "gifted" near cellphone towers to negate the effects. The larger ones make chemtrails harmlessly dissipate.
**btw Wilhelm Reich is a notable person related to this topic.**
Cornelius Nammerfield - Sun, 12 Mar 2017 15:23:18 EST ID:4tmtdVyg No.78599 Ignore Report Quick Reply
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Looks cool tho
Caroline Bomblestig - Sun, 09 Apr 2017 13:26:37 EST ID:E07OVtj0 No.78629 Ignore Report Quick Reply
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u wut?

I would like to know more by Cornelius Sinnerfut - Wed, 22 Feb 2017 11:05:12 EST ID:tYqZ8S2V No.78537 Ignore Report Reply Quick Reply
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Is powdering a carpet with Borax a good way to kill carpet beetles without killing the occupying human?
William Bocklewell - Wed, 22 Feb 2017 12:29:43 EST ID:4tmtdVyg No.78538 Ignore Report Quick Reply
I've used borax to assassinate the ant queen(s) before.

Mix it 1/3 parts borax, 1/3 part sugar, 1/3 part hot water. Let it cool then let the sugar solution sit out in a flat dish or something. I dunno if beetles are as sensitive to borax, but I'm sure they don't have a processing method for borax.
Angus Wiblingdock - Mon, 06 Mar 2017 16:37:04 EST ID:Ja2fAPPl No.78594 Ignore Report Quick Reply
Borax will kill the bugs but any eggs they leave behind will be spared. You'll have to continuously reapply over months to get rid of all of them.

Vaping Safety Questions by breakabond - Tue, 07 Feb 2017 04:15:28 EST ID:LObRvGV/ No.78523 Ignore Report Reply Quick Reply
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I'm going to describe a process and ask some questions at the end (though any helpful feedback is good)

  1. heroin dissolved in isopropyl alcohol
  2. baking soda added
  3. caffeine about 1:1 to lower MP
  4. iso evaporated onto foil

The end result way too baking soda and some went into my throat in scalding liquid form. Good thing heroin kills pain.

  • what's that called when two substances are mixed to create a lower boiling point?
  • Is it safe to vape that baking soda?
  • If I used soda ash, would it be safe to vape that too?
  • any recommendations?
breakabond - Tue, 07 Feb 2017 04:20:53 EST ID:LObRvGV/ No.78524 Ignore Report Quick Reply
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  • would acetone be better?
  • is caffeine soluble in acetone?
  • what about heroin?
  • what about baking soda?
Press - Tue, 07 Feb 2017 17:17:30 EST ID:vUcWj3D5 No.78525 Ignore Report Quick Reply
Its called freezing point depression. Pretty cool shit, back inna days people determined purity and molecular weight with that effect.

Vaping either baking powder or any inorganic nontoxic base wont be a problem unless you inhale too hard.

Concerning the solvent, just look for the swg drugs heroin dossier( guess thats what your chart is based on?) or someother tables to check which solvent is useable for both the HCl and the freebase. You dont have to add the caffeine while thd h is still is in solution as long as you mix it thoroughly

Id recommend using as little solvent as possible while not slowing the dissolution of the base down too much and installing gentoo just to be safe
breakabond - Wed, 08 Feb 2017 00:27:51 EST ID:LObRvGV/ No.78526 Ignore Report Quick Reply
That chart is from the swdrug. We dont have acetone solubiltiy info afaik then. ill stick with IPA

How much Sodium Carbonate -> basify by breakabond !!D0XjIgKF - Sat, 21 Jan 2017 01:17:05 EST ID:zsw9I8fO No.78484 Ignore Report Reply Quick Reply
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How much sodium carbonate would convert 1 molecule of Heroin HCl, or wait, would it be Acetate, yeah.
How much sodium carbonate 1 molecule Heroin acetate -> Heroin base.
7 posts and 2 images omitted. Click Reply to view.
Oliver Fanforth - Tue, 24 Jan 2017 01:21:46 EST ID:LObRvGV/ No.78495 Ignore Report Quick Reply
Oliver Fanforth - Tue, 24 Jan 2017 01:22:27 EST ID:LObRvGV/ No.78496 Ignore Report Quick Reply
Oh deprotofication? Is that the word?
Been 2 years since chem 2, still got it!
Oliver Fanforth - Tue, 24 Jan 2017 01:24:46 EST ID:LObRvGV/ No.78497 Ignore Report Quick Reply
Okay so the solution to avoiding the accidental morphine production then is to perhaps use a weaker base (is ammonia weaker? maybe just baking soda) and quickly extract it afterwards?
Bombastus !uYErosQbLM!!Mybq1UbK - Tue, 24 Jan 2017 01:34:48 EST ID:Req4jw5M No.78498 Ignore Report Quick Reply
Deprotection. Sorry, I was /benz/ed as shit when I decided to legitpost on a few boards. I mean, the information is still good.
Fuck I should teach more when I'm benzed no i really shouldn't

No. You use as little water as possible with an ice bath and then do a vacuum filtration when the freebase precipitates. I don't see why an extraction after freebasing wouldn't work. However, I don't really work with that stuff as much and have no idea if it acts like morphine chemically (it shouldn't due to no active OH groups). Alternatively, You could do the boil down and then acetylate the morphine back into diamorphine.

I'm too chemical, though. I would look up conversion between #3 and #4 or whatever on the internet. Homebaking is much easier than what I would do.
breakabond - Tue, 07 Feb 2017 01:18:50 EST ID:LObRvGV/ No.78522 Ignore Report Quick Reply
So I used sodium carbonate super-saturated (pH was ~10-11) then added some heroin salt -> tried using hexane to extract it -> evaporated.
Evaporating is always the worst step for me, because unless you're doing a massive batch, you end up with such a small amount of freebase residue, so for max efficiency I try to evaporate directly onto foil, which means I try to make a wide dish out of foil, which often ends up breaking and leaking all over my desk, BUT when it does work Im able to vape right off that foil. The alternative would be to put it solid container, but there's ALWAYS some waste when you try to scrape it all up.

So did it get me high? barely. Not enough. Wasteful.

Changing Carbon to Silicon for new life by Frigate - Tue, 24 Jan 2017 17:41:29 EST ID:B2LKOBQC No.78499 Ignore Report Reply Quick Reply
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So me and this girl on one of my classes had come up with substituting Carbon for Silicon that we could get a new form of life, but one of our teachers said it was unbalanced. What does she mean?
3 posts and 1 images omitted. Click Reply to view.
Press - Wed, 25 Jan 2017 16:24:58 EST ID:uHygcoWK No.78503 Ignore Report Quick Reply
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Si has a lower electronegativity which is one way of explaining that Si- bonds with certain elements behave quite different that C- bonds. Alkanes are quite unrractive whereas silanes react rapidly with water for example.

Another example of sadly untrue hypothesis about xenobiology is arsenic using rna analogues. Sadly arsenic acid esters cant substitute phosphoric acid in neither rna nor energy transport systems because they hydrloyse a looot quicker. I think NASA pushed a study about arsenic using bacteria that cost some poor women her career

The abundance of elements throughout the cosmos is also related to how heavy an element is. Thus its less likely that thered be biologies using elements beyond the second period.
Or rather, even if its possible a lot more biology systems will use second period elements.

The only xenobiology hypothesis that i really like is flourine
Using peptides since theyd behave in a distinct folding pattern eventhough F is almost isosteric to hydrogen. With flourine polymers you could build alot of additional kinds of membranes but flourine is "really" electronegative and with its ole 19 which is just a bad number for being made by stars its unlikely to play a huge role. I could dig out a few papers on that but thatd be off topic

Pic related. My kinda xenobiology
Frigate - Wed, 25 Jan 2017 17:42:36 EST ID:B2LKOBQC No.78504 Ignore Report Quick Reply
But why tho? they have similar properties, and I'm asking why they don't work. Not because they normally bond with something else
Frigate - Wed, 25 Jan 2017 17:44:20 EST ID:B2LKOBQC No.78505 Ignore Report Quick Reply
But why tho? I never stated anything about their bonds. I meant they are similar. My main question was why it was unbalanced.
Charlotte Drablingspear - Fri, 27 Jan 2017 21:49:13 EST ID:klMiQ9iI No.78511 Ignore Report Quick Reply
I remember reading somewhere that scientists were able to genetically engineer a bacteria that was able to create silicon bonds, to demonstrate that silicon-based lifeforms are possible and could maybe be found somewhere else in the universe. However I do not believe that they got so far as to create a glucose molecule with silicon instead of carbons. That kind of science is probably decades or centuries away. The reaction you have there is "balanced" in the sense that there are equal numbers of each atom on both sides of the equation. I think your teacher was just trying to tell you that you are full of shit.
Esther Bublingstick - Tue, 31 Jan 2017 21:59:07 EST ID:FMRNgMnb No.78518 Ignore Report Quick Reply
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The electronegativity. Si forms sissy bonds compared to carbon. It's a harsh universe out there... lots of O2 and water. Without the strength and versitility of the carbon bond, silicon based lifeforms would get wrecked by the simplest forces of nature.

Anorganic Chem Q by Cedric Lightfield - Wed, 18 Jan 2017 06:14:04 EST ID:+xNTZBER No.78473 Ignore Report Reply Quick Reply
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So me and my colleague are arguing about whether KOH or NaOH is stronger base. While in practice it is not important, I'd argue that theoretically it must be KOH, as the enthalpy of K+ is lower, therefore KOH will be more likely to dissociate. However, the colleague is buzzing around with a dubious Pkbn from chembuddy which states that pKbn values for NaOH and KOH are 0.2 and 0.5 respectively, indicating that NaOH would in fact be a stronger base (and LiOH the strongest). Why would that be? Pls explain. pic unrel
Bombastus !uYErosQbLM!!Mybq1UbK - Thu, 19 Jan 2017 23:37:12 EST ID:Req4jw5M No.78475 Ignore Report Quick Reply
Electron density is spread out in potassium compared to sodium. This is why potassium carbonate is slightly soluble in acetone compared to sodium and why you see cesium carbonate used in research papers.
The same holds true for hydroxides.
Charlotte Drablingspear - Fri, 27 Jan 2017 22:02:40 EST ID:klMiQ9iI No.78512 Ignore Report Quick Reply
Any difference between the two is likely very small, but I would have to say that NaOH is stronger because Na is less electronegative than K, so it is more willing to give up that OH group. Pure speculation tho
Bombastus !uYErosQbLM!!Mybq1UbK - Sat, 28 Jan 2017 01:26:18 EST ID:ViNIYyYK No.78513 Ignore Report Quick Reply
You are right but that's a product, not a reason. The question is WHY it is more electronegative than potassium and the answer is ironic radius trends.

Where my electrons @@@@@@@@@?
Eliza Grandwill - Sat, 28 Jan 2017 02:36:32 EST ID:vukMbHQH No.78515 Ignore Report Quick Reply

That logic makes no sense to me; I would expect Potassium to be more likely to give up the ghost due it its relatively large electron cloud. The distance of the periphery of the electron cloud to the center of the atoms nucleus should allow easier access to its valence electrons, no?

Which is why pure cesium reacts so violently in water in comparison to lithium, sodium, and potassium.

I guess what I'm saying is NaOH being stronger than KOH goes against my intuition.
Eliza Grandwill - Sat, 28 Jan 2017 02:41:50 EST ID:vukMbHQH No.78516 Ignore Report Quick Reply
Nvm, I gets it.

The ionic association of potassium is stronger than sodium with anions, so you would expect less dissociation as the alkali metals get heavier.

Introduction to /chem/ by Synapse - Wed, 17 Aug 2016 05:46:46 EST ID:rX48mQ3L No.78159 Ignore Report Reply Quick Reply
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Hello, I am a newcomer to this board but it seems cozy enough for me to stay here. It is a dream for me to make a home-lab one day, because univeristy labs (studying medicine) have restrictions and objections against experiments that I'm interested at.

It would be nice if you could tell more about your setups/projects/goals.

>also general current project thread
3 posts and 1 images omitted. Click Reply to view.
Bombastus !uYErosQbLM!!Mybq1UbK - Tue, 15 Nov 2016 01:09:12 EST ID:Req4jw5M No.78347 Ignore Report Quick Reply
both of these are true
Henry Billingbanks - Mon, 12 Dec 2016 06:50:00 EST ID:2mI+Zk9G No.78398 Ignore Report Quick Reply
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Are you here because of the humble bundle?

Cause I'm thinking of getting a lab up after I get that workbench for christmas.

Thomas Cingerfield - Thu, 26 Jan 2017 01:45:25 EST ID:/1/rkG3K No.78506 Ignore Report Quick Reply
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Bombastus !uYErosQbLM!!Mybq1UbK - Fri, 27 Jan 2017 00:42:56 EST ID:zWHMkUyt No.78509 Ignore Report Quick Reply
breakabond - Sun, 05 Mar 2017 10:37:18 EST ID:LObRvGV/ No.78588 Ignore Report Quick Reply
just a test:
>fuckin tolerance

E=MC^2 question by Martin Crepperfuck - Thu, 22 Dec 2016 12:08:21 EST ID:E5ztys4h No.78408 Ignore Report Reply Quick Reply
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So I was randomly thinking about Einsteins most popular contribution to physics, and I have a problem with it:

If E=MC^2, then how is it possible that a mass-less photon can carry any energy?

I expect there's probably a well established answer to this, but in trying to track it down I'm realizing a lot of this stuff is well above my reading level.
12 posts and 1 images omitted. Click Reply to view.
Bombastus !uYErosQbLM!!Mybq1UbK - Sun, 08 Jan 2017 01:04:56 EST ID:zRXgL70Z No.78460 Ignore Report Quick Reply
Good thread.

Also a good question by OP.

nb for answered question
Charles Huvinggold - Wed, 11 Jan 2017 12:00:39 EST ID:rybJ4K29 No.78462 Ignore Report Quick Reply
Hi babe, I just wonder if phen and trypt synth threads are still alive?

Also come visit us on psy every once in a while, you are a good man..
Bombastus !uYErosQbLM!!Mybq1UbK - Thu, 12 Jan 2017 02:03:23 EST ID:8NEuSnNe No.78465 Ignore Report Quick Reply
Thanks! Those threads have more or less died at this point. My experiences with psychedelics is on hiatus since I my consecutive ego deaths on like 750 LSD, 35mg 2-CE, 125mg 4-AcO-DMT, and other doses similar.

That shit actually scares me to the point where weed gives me intense spiritual flashbacks and really need to take a break. Times a changed, I guess. I'll be back soon, though.

Keep grooving in the meantime and ask any question whatsoever.
Rebecca Wemmerwot - Sun, 22 Jan 2017 09:04:53 EST ID:6+KMGshk No.78492 Ignore Report Quick Reply

lol oops
Bombastus !uYErosQbLM!!Mybq1UbK - Sun, 22 Jan 2017 23:00:43 EST ID:iygy/n6D No.78494 Ignore Report Quick Reply
damn where'd that response go to this post. i was gonna response to it too

Guy who wanted to mix two solids for X-Ray analysis by Bombastus !uYErosQbLM!!Mybq1UbK - Fri, 20 Jan 2017 14:52:25 EST ID:jTCURNhV No.78483 Ignore Report Reply Quick Reply
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I guess because of a certain news article, we can't discuss specific molecules like that here............ I suppose the molecule in question is attracting too much media attention so even on a small board such as this, it is unwise to do so?

Sorry anon for killing your thread for asking for specifics.

Where are the fucking units by breakabond !!D0XjIgKF - Fri, 13 Jan 2017 10:55:34 EST ID:zsw9I8fO No.78467 Ignore Report Reply Quick Reply
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Can someone tell me what the units here are?
(<-- image)

source: http://www.pharmpress.com/files/docs/Excipients7e_samplemonos(1).pdf
trypto - Fri, 13 Jan 2017 11:17:46 EST ID:ltcKYWSL No.78468 Ignore Report Quick Reply
Mass percent.

trypto - Fri, 13 Jan 2017 11:20:10 EST ID:ltcKYWSL No.78469 Ignore Report Quick Reply
Whoops. Actually, not mass percent since it's not multiplied by 100. Mass ratio?
Bombastus !uYErosQbLM!!Mybq1UbK - Sat, 14 Jan 2017 00:36:57 EST ID:YTE4hsRA No.78470 Ignore Report Quick Reply
I looked this shit up and it's g in ml. https://pubchem.ncbi.nlm.nih.gov/compound/D-mannitol#section=2D-Structure

Strictly speaking, if I saw this in a research paper, I would think that it said 1 molecule of mannitol dissolves in x molecules of the solvent. This is very lazy of the people who made this.
breakabond !!D0XjIgKF - Sat, 14 Jan 2017 05:57:36 EST ID:zsw9I8fO No.78471 Ignore Report Quick Reply
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