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BWD by Polly Giblingwill - Fri, 18 Aug 2017 19:48:26 EST ID:W19QxMAc No.355554 Ignore Report Reply Quick Reply
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Coming up on my fourth ( ! ) gram+ dexx dose this week; noticed the old thread wasn't bumping.

>That feel when you are at the point where everything is warping and you can't walk straight but you need to go down a flight of stairs...
435 posts and 153 images omitted. Click Reply to view.
>>
Nell Pommerbanks - Wed, 22 Nov 2017 19:16:30 EST ID:YfgCJ32R No.357605 Ignore Report Quick Reply
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This is the time to give my 3rd and final run with MK-801 (aka Dizocilpine). It was a very expensive 10mg sample, and treasured by me far beyond it’s monetary value. But alas I only had 4.4mg left, and I downed it all about an hour ago. Hopefully this takes me far enough that any further dealings I have with Dizocilpine will be because I wanted more really bad, and not because I have unfinished business with this 48hr behemoth. Happy fucking Thanksgiving /dis/!
>>
Hedda Goodlock - Wed, 22 Nov 2017 20:08:14 EST ID:AmEQ1MVR No.357607 Ignore Report Quick Reply
>>357580

Same here on the Ketamine front, but it's whatever as my tolerance is so high Ketamine just isn't really worth it. It takes about 200-250mg for me to hole and even though lower doses are a lot of fun, it's so short-lived that I often end up blowing through all of it without getting as high as I'd like to be. I much prefer longer lasting dissociatives like 3-HO-PCP, 3-MEO-PCP, O-PCE, MXE (where art thou?), and Deschloroketamine

It's whatever, though. I've got some O-PCE and 3-HO-PCP on the way as well as a little 3-MEO-PCP and Deschloroketamine. I should be dissing in a few days
>>
Phineas Pashstodge - Wed, 22 Nov 2017 21:50:43 EST ID:Y7Cz+CU+ No.357608 Ignore Report Quick Reply
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bump. i work at a kennel and dissos helped me understand the inner animal within us all. i love playing with animals while dissed.
>>
Nell Pommerbanks - Thu, 23 Nov 2017 02:06:49 EST ID:YfgCJ32R No.357609 Ignore Report Quick Reply
>>357605
Turns out Dizocilpine sucks ass. It’s dysphoric and antsy. Everything is about craving the bext thing. No comfort to be found. So maybe a 5oz of Delsym will make this all glow. 150mg Doxylamine + 600mg Cimetidine as potentiaters, got Nitrous on deck, and of course THC for days, in flower and concentrate form.

Let’s get weird.
>>
Phyllis Chorrywell - Thu, 23 Nov 2017 06:35:51 EST ID:Qtu9wPew No.357613 Ignore Report Quick Reply
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>>355554
bump


breaking in a new place after moving it by Fucking Pockville - Tue, 21 Nov 2017 04:22:07 EST ID:8w6mjqnK No.357550 Ignore Report Reply Quick Reply
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Do the theards here ever change been gone so long and its all the same.
Side note I'm having an extreme amount of dejavu, wasn't that a thing with dxm?
>>
Rebecca Sillyfuck - Tue, 21 Nov 2017 08:29:46 EST ID:nxf5QKVL No.357556 Ignore Report Quick Reply
>>357550

Been here for about 7 years give or take now. I didnt always post because i get a little tired of trying to word myself correctly everytime the same question got asked again, and there was the time i caught a ban until i turned 18 so i just lurked mostly. Then the tripcodes for dis got turned off and so did the entertainment on dis, whether thats because of tripcodes being removed or not idk, but the fun stopped once tripcodes got taken away so take with that what you will.

Now its just the same cycle of questions over the course of a few months and then repeat. Its always been this way for the bulk of posts, but about a year ago or so there was the occasional creative post with good or interesting topics and questions, many came from tripcodes but not all.

I'm not trying to ke this about tripcodes but that was really the biggest change with the biggest effect on how this board works. Now its just "noobs ask questions and experienced people answer them with a couple fun threads speckled like needles in a haystack". I miss the old days.
>>
Fucking Pockville - Tue, 21 Nov 2017 12:01:44 EST ID:8w6mjqnK No.357559 Ignore Report Quick Reply
>>357556
See now this in it self feels like dejavu. Constiaint dejavu after a trip I had and maybe it was 4th p. But i cant remember it exactly. Hmm.
I do miss this board.
>>
Hedda Crodgeway - Wed, 22 Nov 2017 14:47:37 EST ID:JiIHxaFn No.357589 Ignore Report Quick Reply
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Deja vu is normal on dxm, but if I went into the shit behind that on timelines converging and the multiverse you wouldn't care to believe me. Recently had a really intense deja vu that lasted more than 30 minutes. I just sat back and smirked as I watched the events unfold in my head at least 5 seconds before it happened. We've reached the end of one cycle and a new one is beginning. The old board is on its way back gents, just be patient.
>>
Ebenezer Pedgehit - Thu, 23 Nov 2017 04:26:43 EST ID:Y8Ew2/KU No.357611 Ignore Report Quick Reply
>>357556
Nigga you just kerflapped
>>
Rebecca Dartfield - Thu, 23 Nov 2017 06:16:24 EST ID:Yp0OGhOz No.357612 Ignore Report Quick Reply
>>357589
Odd you would say that. I haven't been around in 4-5 years but for some reason I'm back now.


Pissing jizz with shit after dex by Fanny Trotshaw - Wed, 22 Nov 2017 13:44:06 EST ID:cPyC+x8I No.357588 Ignore Report Reply Quick Reply
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Hey guys we all know DXM fucks your cock to shit and makes it about impossible to cum, I been dexing for a bit now and recently when i went to pass my dexshits I noticed I was simultaneously pissing jizz out of my dick, I was worried this was due to bladder or prostate problems and am wondering if this ever happens to you guys.
It smelt godawful if that helps with diagnosis.
7 posts and 5 images omitted. Click Reply to view.
>>
Hamilton Claydock - Wed, 22 Nov 2017 16:34:02 EST ID:okRphSK/ No.357600 Ignore Report Quick Reply
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>>357597
Sounds like you got a UTI mein negro
Just go the doctor tell the, exactly what you told me (barring the DXMshits but just "hey sometimes I piss this weird yellow shit that looks like cum but smells like rotten feet", they'll test your blood and urine, take some pills, boom no more pissjizz)
Seriously, go to the doctor DXM is not causing g this
>>
Fanny Trotshaw - Wed, 22 Nov 2017 16:43:25 EST ID:cPyC+x8I No.357601 Ignore Report Quick Reply
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>>357600 Aight kinda bummed it wasn't from the DXM but its probably good it isn't.
>>
Hamilton Claydock - Wed, 22 Nov 2017 16:50:25 EST ID:okRphSK/ No.357602 Ignore Report Quick Reply
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>>357601
Godspeed sir
a week of amoxicilyn and you'll prolly be right as rain my man
>>
Hamilton Claydock - Wed, 22 Nov 2017 16:52:03 EST ID:okRphSK/ No.357603 Ignore Report Quick Reply
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>>357602
probably the clap tbh
>>
Albert Wucklespear - Thu, 23 Nov 2017 02:39:06 EST ID:qJrRLvuF No.357610 Ignore Report Quick Reply
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DICKS EVERYWHERE


Visuals by Fucking Derringtan - Tue, 07 Nov 2017 07:14:53 EST ID:aCZW6Wd6 No.357136 Ignore Report Reply Quick Reply
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I find it interesting that a 2nd plat DXM will give me hallucinations of landscapes, great plains, forests, panning over them with a birds eye view like in a Planet Earth episode with David Attenborough(exactly like pic related); while a 3rd+ plat will give me more detailed visuals of "impossible objects" like stuff in Monty Python art, just stuff that doesn't make sense and would take a long time to describe.

I much prefer the former and wish that higher doses would give me more detailed hallucinatory landscapes, but that doesn't seem to happen.
>>
Polly Worthingforth - Tue, 07 Nov 2017 07:56:09 EST ID:+LdGW9Qc No.357137 Ignore Report Quick Reply
>>357136

After extended "visits" to 3rd plat, it would seem that this is totally controllable by your mindset. I'm able to alternate between these very natural landscapes and explore them, but if I'm feeling like I need a dose of surrealism I can just take that mindset and instantly travel to more surrealistic situations and landscapes.
One of the reasons I like DXM so much is that you can learn how to use it, for example if you manage to break the usual sedation the drug changes drastically in its nature and allows you to expand on what kind of experiences DXM brings you.
>>
Shit Blottinghall - Tue, 07 Nov 2017 22:44:54 EST ID:FDw4oep4 No.357150 Ignore Report Quick Reply
>>357137
I miss that divine state of bliss floating over the elysian fields.
>>
William Honeyhall - Tue, 07 Nov 2017 23:28:20 EST ID:qWy30If0 No.357154 Ignore Report Quick Reply
>>357136
Never in my dex tripping history have I ever lastingly flown over natural landscapes.

It describes my only /opi/ experience perfectly though. It was like watching a nature documentary on the Rocky Mountains in 8k at 120hz.
I had never been so relaxed in my life.
>>
Eugene Mozzlehall - Wed, 22 Nov 2017 20:05:29 EST ID:aCZW6Wd6 No.357606 Ignore Report Quick Reply
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Just bumping with a nice little 'anecdote' for those interested.

I was specifically looking for calming scenes on my last trip on just a modest 500mg and amongst what I got was a stay on a cliff ledge overlooking the sea. I scoured google and found something matching my scene


Dxm and you by Matilda Buzzway - Sun, 19 Nov 2017 21:07:30 EST ID:gTtHWID8 No.357501 Ignore Report Reply Quick Reply
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Why do you use DXM?

What makes you come back to the syrup?
>>
Shitting Murdcocke - Mon, 20 Nov 2017 21:54:06 EST ID:tk4VI4I5 No.357540 Ignore Report Quick Reply
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>>357501
I've moved past my days of being a psychonaut and DXM has become more of a thing to do after a long week. A solid 2nd or 3rd plat trip with a video game and some good music is probably similar to others use opis.

Most dissociatives have a very cozy headspace for me. I feel comfortable and at home, and like I can truly relax and let go. Not to mention the afterglow.

I don't think DXM would ever be my first choice for a dissociative to regularly use, but it's just so readily available. If you know what you're doing it's almost like a friend to you.
>>
Wesley Dussleson - Tue, 21 Nov 2017 02:34:45 EST ID:bBbM9Fwz No.357548 Ignore Report Quick Reply
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It was my holy grail, OP. But only for a little while.
>>
Wesley Hoddlehood - Tue, 21 Nov 2017 04:53:44 EST ID:jEPS6M7o No.357552 Ignore Report Quick Reply
Honestly, I used to enjoy the trips, they were fun.
I feel like I developed a bit of an addiction to the DXM and Wellbutrin combo however. My Doctor is giving me the runaround on giving me a benzo for anti anxiety but if I dose 700mg of Dex, I usually have a decent trip if I can stay calm but the afterglow is absolutely amazing and I'm not anxious or depressed for a few days.

I know I can't keep this up, I still only dex about once a week and I'm not sure how much longer I can keep this up, I drink syrup and it's so fucking nasty
>>
Doris Fadgehitch - Tue, 21 Nov 2017 05:50:14 EST ID:Yp0OGhOz No.357553 Ignore Report Quick Reply
>>357552
Well its hard on your liver too, but dissociatives are being shown to have clinical effectiveness for depression. Its also worth mentioning that a lot of the drugs used for depression are used on anxiety as well. That being said the afterglow phase and maybe even during the trip might be a good time to try and work through your personal problems that lead to said depression and anxiety. Shit, it works/worked for me.
>>
Samuel Pockfield - Wed, 22 Nov 2017 15:22:01 EST ID:tk4VI4I5 No.357592 Ignore Report Quick Reply
>>357552
You should not use DXM to treat anxiety or depression. There is simply too much risk of psychosis after a certain point. Benzos really do help anxiety, but if you're doctor is giving you a hard time then I would suggest a gabapentinoid like gabapentin or pregabalin. I take 300mg gabapentin three times a day and it's helped my anxiety a lot and I've been able to taper down my clonazepam dose from 1mg a day to 0.5mg a day. Without the gabapentin, changing my clonazepam dose would have me fuckin exploding with anxiety but I'm doing alright and it's less sedating which is nice but I still am able to relax and get to sleep every night.


ɳεω 尺ØŁŁ ɬɧཞɛąɖ by Basil Droddlelock - Mon, 20 Mar 2017 19:38:29 EST ID:n+9WxiwR No.352812 Ignore Report Reply Quick Reply
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Old one hit bump limit. You know the drill.

Odd dose that shit
Even maybe not
Zero re-roll
Dubs take double/hole dose
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Basil Siddlegold - Wed, 22 Nov 2017 03:00:25 EST ID:klIZn3jN No.357582 Ignore Report Quick Reply
Rolled
Ppl q
>>
Martin Fanham - Wed, 22 Nov 2017 07:47:07 EST ID:Y7Cz+CU+ No.357585 Ignore Report Quick Reply
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was planning to dex today but called into to work. roll cus i can work dissed.
>>
Nicholas Summledale - Wed, 22 Nov 2017 09:53:51 EST ID:Lb5RxTsI No.357587 Ignore Report Quick Reply
>>357585


Currently at work. Rolling. Can also work dissed. Can not buy /dis/ at work. Will I /dis/ after work?
>>
Frederick Nicklehall - Wed, 22 Nov 2017 14:57:52 EST ID:arDQEB2E No.357590 Ignore Report Quick Reply
>>352812

Luck be a lady tonight
>>
Frederick Nicklehall - Wed, 22 Nov 2017 14:58:18 EST ID:arDQEB2E No.357591 Ignore Report Quick Reply
>>357590

Reroll


Cool stuff to watch dissed? by Oliver Shakefield - Sun, 12 Nov 2017 20:14:05 EST ID:/+tA2WuY No.357293 Ignore Report Reply Quick Reply
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I generally watch Alice in Wonderland but was wondering if anyone has any cool suggestions for something enjoyable while in a /dis/ state.

I hope you are all having a most fantastic night and thank you for reading this.
Bingle hop bo diddle swap, jibble jobble my friends.
28 posts and 9 images omitted. Click Reply to view.
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Reuben Bandlefet - Tue, 21 Nov 2017 19:12:14 EST ID:AmEQ1MVR No.357573 Ignore Report Quick Reply
>>357496

Oh and I second Akira. It's an insanely captivating film. If you can sit down and read the manga while dissed, I highly recommend that as well, as it's honestly better (the film ends about halfway through the manga and changes a lot of events). Though they're both great for their own reasons.
>>
William Mecklewill - Tue, 21 Nov 2017 20:43:00 EST ID:aCZW6Wd6 No.357574 Ignore Report Quick Reply
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>>357531

>You will never be Vader in the hallway scene at the end of Rogue One
>On dxm you will be
>>
Samuel Pockfield - Tue, 21 Nov 2017 21:59:37 EST ID:tk4VI4I5 No.357579 Ignore Report Quick Reply
>>357574
I fuckin hated that they had to throw in Vader in Rogue One, it felt so forced. Same with R2-D2 and C-3PO giving that throwaway line. The movie was actually trying to stand on its own, don't bog it down with janky Vader who sounds super old.
>>
Priscilla Bardwell - Tue, 21 Nov 2017 22:31:13 EST ID:OcRh0oMq No.357581 Ignore Report Quick Reply
>>357293
try going out into the woods
>>
Esther Darrytore - Wed, 22 Nov 2017 06:05:59 EST ID:IqgnmU+/ No.357584 Ignore Report Quick Reply
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>>357293
Pitch blackness or the inside of your eyelids, ideally you won't be able to tell the difference.


mania by Phineas Crogglelutch - Tue, 21 Nov 2017 10:40:53 EST ID:Qt58CjR7 No.357557 Ignore Report Reply Quick Reply
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hey gusye so i use dxm occasionally but i've been seriously considering buying some rc dissociatives to go deeper into the experience. one thing i'm concerned about though is mania, i've seen the liveleak videos and all that, but i don't really know more than that. does anyone here have firsthand experience with /dis/ mania / any tips on how to prevent it. thx
3 posts omitted. Click Reply to view.
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Rebecca Sillyfuck - Tue, 21 Nov 2017 18:12:43 EST ID:nxf5QKVL No.357568 Ignore Report Quick Reply
You dont prevent it, you recognize and control it. Take things very slow and work your way up over time and you should be able to recognize when you're getting a bit manic and delusional most of the time, but by the description of these mental states you'll never notice it right away, but eventually just realize that you were thinking some crazy shit or acting weird and stupid in ways you wouldnt when sober. You've really got to experience some mania and delusions to start recognizing them. In gonna give some examples but youve got to understand that i fully believed these things at the time and you will too once you go through. Ive never gone pcp-negro mode but heres some short examples:

>on 3meopcp I picked up my desert eagle bb gun and thought it was a real gun that was loaded so i was scared a bit but i still wound up waving it around, checking the clip and then forgetting it was a bbgun again soon as i put it back in, and repeatedly oulling the trigger scared itd shoot

>during summer of sigma I did infrasigma (ive told the story before many times) I did infrasigma for a week and then smoked some dmt resin from my pipe and watched enter the void and thought it was about me and that i died somehow and forgot and noq im watching my life story.

>while on high 3rd to 4th plateau dxm slow dosed and a tab of acid and doing whippets i watched futurama and began to think the show was a message from the future sent back for me to be able to change the future and stop the future from being ran by a reagen head and mom corp

>recently i watched a movie called everlife about a drug that makes you live an entire other life while on 55mg of memantine, about a couple tabs of really amazing acid, and about 200 whippets while with my gf and i thought it was actually happening and that at the end of the movie something really big was going to happen like i was going to die or like my relationship was going to fail after watching it.

>for a few months after watching hannibal during a 3meopcp binge I actually thought i was a sociopath and started to see a therapist about it.

>when i did dxm daily i thought i was god in mortal human form with no recollection of who i was and i was here to see how the world was going so after my death i could have a better understanding of the world and change it for the better. (This one is partially true still but thats a complicated and off topic religious discussion that im sure youve either had with yourself or will have with yourself during a trip one day.)

Hearing about delusions doesnt give much of a leg up, but just be vigilant and realize the extreme ones and stop those right away. I have gotten subtle thoughts of killing people or being followed or other paranoid thoughts but youve just got to realize those sorts of things are completely crazy which isnt hard. Its the ones you get elaborate on that seem slightly feasible at the time thst get tricky. You can change the story any way you want to fit the story youve got going on but eventually something will crumble and youll come back to soberiety and realize how craxy it actually was.
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Doris Sankinkark - Tue, 21 Nov 2017 18:44:48 EST ID:AmEQ1MVR No.357570 Ignore Report Quick Reply
>>357565

Yeah, and mania pretty much only happens from excessive redosing, so if that's what bothers you about doing dissociatives (keep in mind that it's not just dissociative RC's that can cause this, it's ALL dissociatives to varying degrees, even and sometimes especially DXM), so if you're worried about that, this is something you need to do.
>>
William Mecklewill - Tue, 21 Nov 2017 21:09:09 EST ID:aCZW6Wd6 No.357575 Ignore Report Quick Reply
>>357568

Haha. I think you're talking about OtherLife (2017)
>>
Caroline Sacklewater - Tue, 21 Nov 2017 21:30:43 EST ID:nxf5QKVL No.357577 Ignore Report Quick Reply
>>357575

Yes thank you lol. Great movie for tripping to.
>>
William Mecklewill - Wed, 22 Nov 2017 04:35:13 EST ID:aCZW6Wd6 No.357583 Ignore Report Quick Reply
>>357577

I had this delusion last trip. I was sitting on my bed against my sliding wardrobe and I sat up upbruptly and knocked the sliding door out of place. In the space of a few seconds I established this delusion that a Chinese company was responsible. It was so weird, it didn't even make the slightest sense. I suppose thats why you call it a delusion.


Triqgles by John Duckfoot - Tue, 21 Nov 2017 21:51:24 EST ID:h46isMGR No.357578 Ignore Report Reply Quick Reply
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What a drug.


DXM by Isabella Worthinglock - Tue, 14 Nov 2017 02:43:52 EST ID:Nv9N46Zp No.357338 Ignore Report Reply Quick Reply
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Yo /dis/! Whatup. Back in the day I did a lot of cs and syrup, but i stopped for a while. Anyway, last night I was bored as fuck, round 8 o clock I got a bottle of vicks 44 that id been saving for a bit. Never tried it before, needless to say it tasted fucking ass.
Took me a long time to get it down and in the end i threw it up... I kinda felt the dxm tho. Still feeling it a bit. :)
Just wondering what are your preferred/tastiest/least-vomit inducing methods of administration
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Esther Pucklefuck - Mon, 20 Nov 2017 06:15:23 EST ID:egvxZN6M No.357521 Ignore Report Quick Reply
>>357485
>Gel caps resist acidity pretty well as they are basic

Surely if they were basic they'd react more rapidly with stomach acid than if they were neutral PH?
Not sure you've thought this through, fam.
>>
Rebecca Worthingwill - Mon, 20 Nov 2017 07:36:01 EST ID:cdVEOWgN No.357522 Ignore Report Quick Reply
>>357513
Or you could just leave as is and wash them down with carbonated drink. They float due to the carbonation, or better yet cover them with a sugary beverage and microwave them on a low low setting until they burst. Pour the liquid in a nonstick sprayed mold or silicone ice cube tray and wait until they set up. Viola dxm jello shots or add a piss load of syrup and fruit pectin mixture to the liquid pour on a sheet pan and cut into cube and roll in powdered sugar for DXM turkish delight. Seriously you name I've tried it.
>>
James Murdfuck - Mon, 20 Nov 2017 13:01:41 EST ID:VAC1hXLf No.357523 Ignore Report Quick Reply
>>357521
I just read it a while back. That theyre barely on the basic scale but just enough to neutralize stomach acid, which is why everyone recommends drinking acidic soda for gels.
>>
Archie Clayfoot - Mon, 20 Nov 2017 15:54:29 EST ID:aCZW6Wd6 No.357527 Ignore Report Quick Reply
>>357402
>>357403

I think its physiological differences.
>>
Doris Fadgehitch - Tue, 21 Nov 2017 05:56:09 EST ID:Yp0OGhOz No.357555 Ignore Report Quick Reply
>>357523
Or an orange or even a small bite to eat stimulates stomach acid production.


"Dissociative taste"? by Clara Drogglewutch - Mon, 20 Nov 2017 16:44:22 EST ID:rYejH+Vu No.357529 Ignore Report Reply Quick Reply
I have a fair experience with DXM, DCK, and 3-MeO-PCP. Of these three I noticed they all gave a strange taste in the mouth during the trip (not the taste of the chemicals themselves), and it's not a bad taste by any means.

Does anyone else notice this and is it present in other (or all) dissociatives? If so, what's the science behind it?
>>
Hamilton Bibblebanks - Mon, 20 Nov 2017 19:19:20 EST ID:/bZQ+LlZ No.357536 Ignore Report Quick Reply
Yep.

I always imagined it was a similar effect to when you IV some drugs, how you can taste them in your mouth (never experienced this personally, but I have heard it is common), but a lot of dissociatives have a strong taste, so you can taste them or their metabolites for the duration of the experience.

I like it, myself. It's a very hard to describe taste, kind of sweet but not really. A friend of mine never gets this effect but he always smells it instead.

The only dissociatives I've tried that don't have this effect are DXM and 3-MEO-PCP. 3-MEO will sometimes cause it but it rarely does for me. MXE would cause it very strongly, and after a year or so of only doing 3-MEO-PCP and then finally getting some O-PCE, 3-HO-PCP and 2-Fluorodeschloroketamine, I remembered that this was an effect of dissociatives, and really enjoyed having it back. I also noticed these three compounds seemed to produce a much sweeter taste than I remember other compounds causing. They also all tasted sweeter when snorted. I wonder if this was psychosomatic as I may have grown to like dissociatives much more in general.
>>
Shitting Murdcocke - Mon, 20 Nov 2017 21:46:57 EST ID:tk4VI4I5 No.357539 Ignore Report Quick Reply
>>357529
DXM gives me a faint citrus taste. I once thought it was just the taste of Arizona tea persisting, but I tried only drinking water one trip and could still taste it.

MXE always tasted very strange. Like faintly metallic but not quite. I really could never put my finger on it. There was almost a texture to it, as if the air was doughy and touching my tongue.

As for the science behind it, it could just be that you are tasting it or some metabolite in a manner similar to how the above poster describes like when you IV stuff. I also am just gonna pull a guess out of my ass that serotonin plays some role in taste and smell, because I'm sure many have experienced a significantly altered sense of taste and smell on serotonergic psychedelics, not to mention DXM makes me really sensitive to strong smells.
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Doris Fadgehitch - Tue, 21 Nov 2017 05:54:22 EST ID:Yp0OGhOz No.357554 Ignore Report Quick Reply
>>357539
Its funny, now that you mention it DMT taste like the combination of forest floor and desert wind if smells were a taste.


Slow dosing throughout the day? by Doris Bunridge - Thu, 09 Nov 2017 07:45:14 EST ID:/+tA2WuY No.357198 Ignore Report Reply Quick Reply
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Anyone here have any experience with taking small doses incrementally throughout the day?
Like, taking a few gelcaps every hour or two throughout the day and then downing a bottle upon arriving back at home?
25 posts and 2 images omitted. Click Reply to view.
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Charlotte Murdworth - Mon, 20 Nov 2017 23:07:44 EST ID:IqgnmU+/ No.357544 Ignore Report Quick Reply
>>357538
The levels of enzymes is down to genetics. Especially with CYP2D6 which is responsible for metabolising DXM -> DXO.

Yeah, that's what an inhibitor does and something which is metabolised by a given enzymes is a substrate of that enzymes. An inhibitor reduces production of a given enzymes, a substrate uses up an amount of that enzyme, which is why taking multiple substrates of a single enzyme can result in similar outcomes to enzymes inhibition.
https://en.wikipedia.org/wiki/Competitive_inhibition
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Nicholas Pengerdurk - Mon, 20 Nov 2017 23:28:37 EST ID:VAC1hXLf No.357545 Ignore Report Quick Reply
>>357533
Definitely responded to this earlier and saw my comment posted. Whoever deleted it, fuck you.

Lrn 2 ascend past repeated dosing with polistirex and hbr fam, dumbass. We cant all have perfect enzymes for hitting sigma, not everyone can be born great, sorry fam. Also, we're posting in a drug forum here. Don't expect me to write with the pompous eloquence of an english major. Go to college for that, fuck off with your shit vibes.
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Shitting Murdcocke - Mon, 20 Nov 2017 23:33:32 EST ID:tk4VI4I5 No.357546 Ignore Report Quick Reply
>>357544
> a substrate uses up an amount of that enzyme, which is why taking multiple substrates of a single enzyme can result in similar outcomes to enzymes inhibition.

Thank you! This had really been bugging me. I had sort of reached this conclusion on my own but I wasn't sure. The Wikipedia page is not one that I had actually come across before, so I will give it a read. Actually just took 600mg so I'm gonna leave the tab open and come back to it later.

One question. How do enzymes factor into tolerance? I mean, how does the liver become more efficient at metabolizing a given substrate after repeated exposure to it? This does happen, right? I imagine this might be similar in principle to receptor downregulation but I don't actually know the mechanism.
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Clara Deshfure - Tue, 21 Nov 2017 04:09:09 EST ID:aCZW6Wd6 No.357549 Ignore Report Quick Reply
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Man I am so interested in slow dosing. And redosing. It all seems so fascinating.
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Doris Fadgehitch - Tue, 21 Nov 2017 04:46:39 EST ID:Yp0OGhOz No.357551 Ignore Report Quick Reply
>>357545
Online or daily life quit saying "fam" god dammit. Although, am I am kinda laughing on my end so SLAYER here bro. Expecting more out of any community is the only way to elevate it from obscurity my friend. I consider myself a psychonaut and at least half the people I've talked to on here seem to think similarly.
Anyway, what you've described just sounds like regular fucking plateaus man. I've dicked around with citrate, hbr, but never polistirex. So I can't say about it but it just makes for really low peaks even at retarded fucking doses. Enzyme inhibition is the only way to go. If you are projectile vomiting then you need to learn to sit the fuck down and make some antiemetic tea(ginger, chamomile, maybe lavender). I get the feeling you either haven't experienced higher plats or youthem't remember them, because even scraping high plats or shooting for sigma I was seeing the real world but I wasn't. I fell through the god damn ceiling bro, and that was just the start of what I thought was a new plateau.


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