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Schizophrenia, antipsychotics and MDMA by Edward Dartham - Sat, 26 May 2018 13:39:20 EST ID:nFfKhAEn No.226381 Ignore Report Quick Reply
File: 1527356360636.jpg -(42689B / 41.69KB, 300x299) Thumbnail displayed, click image for full size. 42689
My GF is schizophrenic and wants to try MDMA. She's on risperidone and quetiapine.

How safe is it for her to try MDMA guys? She's never done drugs before because of her diagnosis and wants to live a little.
What could go wrong?
How likely is it to go wrong?
Walter Pebberstock - Sat, 26 May 2018 13:47:12 EST ID:RYsM4AsG No.226382 Ignore Report Quick Reply
>What could go wrong?
the full scale unraveling of her grip on reality, possibly some bad reaction with the medications that fuck up her brain chemistry

For what its worth I have schizophrenia, I did a lot of MDMA and psychedelics in the year before it fully presented and collapsed into psychotic paranoia, I havn't done MDMA since but it took me years to be able to smoke even weed without it instantly flipping a switch of manic delusions, I still can't comfortably take psys

I'd say start small if she's never done drugs before jumping right into something that powerful, and do serious research or consult a doctor to make sure the cocktail with her meds isn't gonna cause serotonin syndrome or something
Clara Suddlecocke - Sun, 27 May 2018 10:42:17 EST ID:t6ONk5ng No.226386 Ignore Report Quick Reply
she won't feel anything as quetiapine is so fucked it's basically blocks all receptors
Molly Dipperbanks - Mon, 28 May 2018 17:10:25 EST ID:6t2aVBFh No.226389 Ignore Report Quick Reply
e makes me feel crazy as shit
Wockstar - Mon, 28 May 2018 21:35:05 EST ID:7IK0d9iB No.226391 Ignore Report Quick Reply
Pretty sure she'll be fine. Antipsychotics don't affect serotonin receptors so there is no risk of her getting serotonin syndrome. She might roll a little less hard than normal but other than that nothing will happen.
Sophie Gannerwet - Tue, 29 May 2018 03:21:14 EST ID:9KQ6dHYu No.226392 Ignore Report Quick Reply
Quetiapine has the following pharmacological actions:[49][50][51][52][53][54][55][56]

Dopamine D1, D2, D3, D4, and D5 receptor antagonist
>Serotonin 5-HT1A receptor partial agonist, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7 receptor antagonist, and 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F receptor ligand
Frederick Pirringman - Wed, 30 May 2018 18:03:10 EST ID:PwQetLkX No.226393 Ignore Report Quick Reply
Risperidone and quetiapine will both block a lot of the pleasurable effects of MDMA or methamphetamine. It's a waste of money.
Oliver Tillingwell - Sat, 02 Jun 2018 05:57:57 EST ID:Sn/g5A+w No.226399 Ignore Report Quick Reply
Come on man. No, don't give you schizo gf MDMA.
Albert Blullerstirk - Fri, 08 Jun 2018 21:32:23 EST ID:83KWJaZQ No.226412 Ignore Report Quick Reply
It is usually advised that if you have any profound mental illnesses like / similar too what you're girlfriend has then as a general rule of thumb, NO. Psychoactive substances can have an unbelievably devastating on an individuals brain chemistry and perception of reality; even more so if she is on medications already to manage her condition. I can't stress how much of a bad idea this is.
Fanny Fuddlewetch - Mon, 11 Jun 2018 05:52:01 EST ID:oi8YhdoH No.226414 Ignore Report Quick Reply
From what I heard, MDMA could supress her symptoms but during the comedown (if there is any) they will intensify.
Walter Nurringbury - Fri, 15 Jun 2018 21:17:41 EST ID:f115uJEm No.226427 Ignore Report Quick Reply
Get out get out get out get out get out

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