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420chan's Canada Cannabis Legalization Logitech Giveaway

We're giving away Logitech hardware to lucky 420chan users to celebrate recreational legalization on October 17!
Round 1 Giveaway Entry     Discussion Thread
Schizophrenia, antipsychotics and MDMA by Edward Dartham - Sat, 26 May 2018 13:39:20 EST ID:nFfKhAEn No.226381 Ignore Report Quick Reply
File: 1527356360636.jpg -(42689B / 41.69KB, 300x299) Thumbnail displayed, click image for full size. 42689
My GF is schizophrenic and wants to try MDMA. She's on risperidone and quetiapine.

How safe is it for her to try MDMA guys? She's never done drugs before because of her diagnosis and wants to live a little.
What could go wrong?
How likely is it to go wrong?
>>
Walter Pebberstock - Sat, 26 May 2018 13:47:12 EST ID:RYsM4AsG No.226382 Ignore Report Quick Reply
>What could go wrong?
the full scale unraveling of her grip on reality, possibly some bad reaction with the medications that fuck up her brain chemistry

For what its worth I have schizophrenia, I did a lot of MDMA and psychedelics in the year before it fully presented and collapsed into psychotic paranoia, I havn't done MDMA since but it took me years to be able to smoke even weed without it instantly flipping a switch of manic delusions, I still can't comfortably take psys

I'd say start small if she's never done drugs before jumping right into something that powerful, and do serious research or consult a doctor to make sure the cocktail with her meds isn't gonna cause serotonin syndrome or something
>>
Clara Suddlecocke - Sun, 27 May 2018 10:42:17 EST ID:t6ONk5ng No.226386 Ignore Report Quick Reply
>>226382
she won't feel anything as quetiapine is so fucked it's basically blocks all receptors
>>
Molly Dipperbanks - Mon, 28 May 2018 17:10:25 EST ID:6t2aVBFh No.226389 Ignore Report Quick Reply
e makes me feel crazy as shit
>>
Wockstar - Mon, 28 May 2018 21:35:05 EST ID:7IK0d9iB No.226391 Ignore Report Quick Reply
Pretty sure she'll be fine. Antipsychotics don't affect serotonin receptors so there is no risk of her getting serotonin syndrome. She might roll a little less hard than normal but other than that nothing will happen.
>>
Sophie Gannerwet - Tue, 29 May 2018 03:21:14 EST ID:9KQ6dHYu No.226392 Ignore Report Quick Reply
>>226391
Quetiapine has the following pharmacological actions:[49][50][51][52][53][54][55][56]

Dopamine D1, D2, D3, D4, and D5 receptor antagonist
>Serotonin 5-HT1A receptor partial agonist, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7 receptor antagonist, and 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F receptor ligand
>>
Frederick Pirringman - Wed, 30 May 2018 18:03:10 EST ID:PwQetLkX No.226393 Ignore Report Quick Reply
Risperidone and quetiapine will both block a lot of the pleasurable effects of MDMA or methamphetamine. It's a waste of money.
>>
Oliver Tillingwell - Sat, 02 Jun 2018 05:57:57 EST ID:Sn/g5A+w No.226399 Ignore Report Quick Reply
Come on man. No, don't give you schizo gf MDMA.
>>
Albert Blullerstirk - Fri, 08 Jun 2018 21:32:23 EST ID:83KWJaZQ No.226412 Ignore Report Quick Reply
>>226381
It is usually advised that if you have any profound mental illnesses like / similar too what you're girlfriend has then as a general rule of thumb, NO. Psychoactive substances can have an unbelievably devastating on an individuals brain chemistry and perception of reality; even more so if she is on medications already to manage her condition. I can't stress how much of a bad idea this is.
>>
Fanny Fuddlewetch - Mon, 11 Jun 2018 05:52:01 EST ID:oi8YhdoH No.226414 Ignore Report Quick Reply
>>226381
From what I heard, MDMA could supress her symptoms but during the comedown (if there is any) they will intensify.
>>
Walter Nurringbury - Fri, 15 Jun 2018 21:17:41 EST ID:f115uJEm No.226427 Ignore Report Quick Reply
Get out get out get out get out get out
Get
>OUT
>>
Martin Dipperhood - Tue, 24 Jul 2018 17:45:32 EST ID:kyhKRb7D No.226497 Ignore Report Quick Reply
>>226381
man if anything give her weed/
>>
Phyllis Chabbletet - Tue, 24 Jul 2018 23:35:02 EST ID:NbdMiaxv No.226498 Ignore Report Quick Reply
>>226497
false lol
>>
Jarvis Fanfoot - Fri, 03 Aug 2018 14:33:12 EST ID:/2rRCenU No.226516 Ignore Report Quick Reply
Psychology is a weird fucking thing man.
In 2011 when I was in high school I had a psychotic break and I thought people were constantly trying to poison/drug me. I smoked some weed once and it completely fucked my head. It led to extreme alcoholism just to deal with it. Now I'd like to say it's "cured" but I still struggle with it. I can smoke pot now and not lose my shit anymore which is nice. I dunno man, just make sure she is totally prepared to lose her mind if the trip goes bad.
>>
Sophie Grimfield - Fri, 03 Aug 2018 15:16:08 EST ID:zR7s7n9q No.226517 Ignore Report Quick Reply
1533323768715.png -(487931B / 476.50KB, 1828x1801) Thumbnail displayed, click image for full size.
If she's stable enough that she could be left alone detoxing from her meds without any serious concern for her safety or mental health then she could probably risk a half-dose without much problem. Still, if she is that stable better to just quit the meds and take the MDMA when they're out of her system and do a trial with M to see if it's a better medication.
>>
Augustus Gomblespear - Tue, 07 Aug 2018 11:11:55 EST ID:dNAVAUfT No.226522 Ignore Report Quick Reply
Iono but when i was on risperidone i did coke all the time cut
High in half tho
>>
Hannah Moffingnark - Tue, 07 Aug 2018 17:26:07 EST ID:4Rfci+aB No.226523 Ignore Report Quick Reply
Yeah, No
>>
Angus Brerryshit - Wed, 08 Aug 2018 10:22:37 EST ID:f748SiE+ No.226530 Ignore Report Quick Reply
ive got schizophrenia and i took mdma today.

id say it felt like i was slipping into my mind a bit too much and thinknig about stuff. but i didn't feel anything like i was going into psychosis... which i can feel because my mind races and i get weird tunnel vision and other things

id say its probably not wise to. even weed isn't but I still smoke everyday too. mines isnt that bad in my last psychotic episodes was a few months back.

psychosis just feels like it comes and go. I think i could take a high hit of psychedelics and still have my pills and feel fine. benzos cut my psychosis in that if im tyhinking paranoid, pissed off that ppl are poisoning me or something, i pop a xanax and calm down and i stop being paranoid. the antipsychotics kind of just dull you so you can't think
>>
Edward Blackhood - Mon, 13 Aug 2018 00:51:10 EST ID:T2oPvqwU No.226541 Ignore Report Quick Reply
>>226381
>schizophrenia
>has to take two antipsychotics
>taking a recreational drug that is known to induce mania
>What could go wrong?

Don't do it dumbass.


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