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Do you take the 'lttle' drugs by Nathaniel Smallbanks - Tue, 13 Mar 2018 05:00:35 EST ID:AzZIuaNf No.55324 Ignore Report Quick Reply
File: 1520931635964.jpg -(218197B / 213.08KB, 817x880) Thumbnail displayed, click image for full size. 218197
like painkillers for headaches, sleeping pills for sleeping, antihistamines for allergies etc

I wonder if all that shit will add up in the end and contribute to dementia or something.
>>
Shit Bemmleville - Wed, 14 Mar 2018 01:01:15 EST ID:TZRVuoWi No.55325 Ignore Report Quick Reply
>>55324
well question cat. Many drugs are known to cause issues. Take allive, or
Tylenol. Allieve, naproxin? sodium. The commercials make it seem like
a great drug for long lasting relief from pain. But the instructions warn
to not exceed more than, I believe 4 doses in 48 hours.

If it is not working for pain, people will possibly take more.
The commercials seem to indicate portray that it can be
taken long term in the way it is presented.

Ibuprofen is likely the least harmful of over the counter pain revilers.
Aspirin as well for most.

Drugs, some have not been studied just long enough to say, well this is harmful
in the long term. Many do get pulled. Some replace these, which can be worse.

Corporations do try to hide negative effects of prescription and non-prescription
drugs. Loss of $$$$ settling lawsuits is usually nothing compared to keeping
drugs in circulation.

As for drugs, nicotine in tobacco. Causes a lot of harm long term. Corporations know
if they lose a smoker they need to replace with another. $$. Documents of these
corporations surface, knowing what the effects are. It is a lot to do with politics.
>>
Fuck Brebbleshaw - Sat, 24 Mar 2018 12:44:26 EST ID:hzIAUBhA No.55335 Ignore Report Quick Reply
Most of the 'small drugs' would prevent dementia if anything. Take paracetamol. Sure, it's bad for your liver if you take too much, but it's still an endocannabinoid modulator through its FAAH inhibition. NSAIDs would help by reducing inflammatory processes in the brain. Even antihistamines have a fair history of use for antidepressant purposes. DXM may help against OCD.

The real problem comes with other side effects these substances produce. Alongside the aforementioned liver damage, NSAIDs tend to damage the bowels. Some antihistamines prolong QT intervals. This is why they're meant to be used sparingly.
>>
Caroline Dallerforth - Mon, 02 Apr 2018 13:01:14 EST ID:Rl1gAmmt No.55357 Ignore Report Quick Reply
>>55324
great question, this is studied quite a bit. for many drugs it's hard to pinpoint exact issues and make conclusions, but on the other hand, for a lot of drugs we understand how they work and can make pretty educated guesses. if there's absolute no theory that would suggest x drug causes dementia, why would we worry about it? are there increased rates of dementia in x generation? what drugs were more prevalent in these people? etc. this stuff is compiled and it helps us make these decisions. tylenol can contribute to liver problems later in life, advil can contribute to stomach issues, etc.

in reality, doctors know this stuff isn't an issue unless you're taking large amounts. if you take tylenol a few times a month, you aren't going to get cirrhosis at 60. maybe if you take tylenol and drink heavily, then you've got good reason to be concerned. before a doctor prescribes any medication, he considers the risk and how appropriate it would be to prescribe. sleeping pills? if you've got a stressful project at work for the next month, you aren't going to damage your brain by taking zopiclone for a week.

at the end of the day, a large part of medicine is quality of life. ask yourself - would i rather ease my symptoms of pain for my entire life in exchange for 5 less years of life?
>>
A_Wizard !cMZsY.BCnU!!vVWR8L52 - Wed, 04 Apr 2018 16:58:29 EST ID:p98oIwAn No.55358 Ignore Report Quick Reply
>>55325
This. ibuprofen is a bigger health hazard than taking a puff of weed or eating some akuamma seeds.
>>
A_Wizard !cMZsY.BCnU!!vVWR8L52 - Fri, 06 Apr 2018 03:33:16 EST ID:p98oIwAn No.55360 Ignore Report Quick Reply
>>55325
>ibuprofin least harmful
Despite it causing stomach, liver (it was the liver, right?), and central nervous system issues? Admittedly, this is in high quantities or with sustained issues, but ibuprofin is fucking brutal. I'm confident that it's the leading cause of many health issues had by US veterans after they get out, since the military's answer to every medical problem is "Drink a gallon of water and take a gram of ibuprofin every two hours"
>>
Reuben Fimmlefoot - Sat, 07 Apr 2018 03:06:10 EST ID:seInJVW2 No.55363 Ignore Report Quick Reply
>>55360
All NSAIDs do that and opiates as well (do not let /opi/ tell you shit about the long-term physical effects of opiates because they don't know fuck all). Acetaminophen would be preferable if not for liver damage, as it does not pose risk to cardiovascular function save a temporary increase in BP. There's really no good options here. The best in terms of side effect profile is the endocannabinoid modulator, and this might be the future direction painkiller R&D goes down since it seems to come with the least generalized risk.


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