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U-47700 by Reuben Fuckinghood - Thu, 23 Mar 2017 08:06:53 EST ID:uPjbLXXg No.575684 Ignore Report Reply Quick Reply
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So, I can't help but feel there is a bit of a stigma against this online, as people have read about the properties of the drug or heard of some bad anecdotal experiences and then get their mind made up on the drug and spread their opinion on it as if they have first hand experience when they're just parroting what seems to be the consensus - that the stuff is shit.

I find it's the best opioid I've done in all ways, even the WD is nice because it's so short. The high is noticeably better than heroin and it's more potent so you need less to hit that sweet spot, everyone I know who has tried u4 and heroin prefer u4, I've sold it for 100 dollars a point and people have opted for that instead of a $50 point of pure heroin, and people will happily return for more, even saving their money for U4 if it means going dry when H is available instead. So has anyone here actually tried much of this or does the internet just have its hivemind made up about this wonderful chem? I've used it for about a year straight now and I'm still lovin' it.
2 posts omitted. Click Reply to view.
Ernest Sunnertet - Thu, 23 Mar 2017 15:50:06 EST ID:26eitY8C No.575704 Ignore Report Quick Reply
i managed to totally avoid wds after getting hooked thanks to kratom so ill never think too badly of it. however, my nose still has not recovered and i almost od'd daily. came with the best fucking stealth ive had when i ordered it around the time of the ban. havent bothered since because id rather not die and its the opi i can control my usage the least
Dr. Mario !gWLn19/oKs - Thu, 23 Mar 2017 15:54:46 EST ID:NZSaVF2M No.575706 Ignore Report Quick Reply
He said pure heroin.

$50/point for 100% pure would in theory be equal to 10/point for 20% pure street heroin.

I wouldn't be surprised if the average heroin is as cut as 20% pure in a lot of places. Maybe 10-25% pure with a bit of fent analog to boost it back up.
WIAKR+Pa - Thu, 23 Mar 2017 18:22:51 EST ID:XRqY18TH No.575720 Ignore Report Quick Reply
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How much U-47700 were you using, and by which ROA? How quickly did you replace it with kratom, with which type, and in what amount? I'm looking to do something similar, but with PST. How often do/did you find you had to redose kratom in order to avoid withdrawals? Thank you!
James Manninglin - Thu, 23 Mar 2017 22:16:16 EST ID:N8JKcyEm No.575729 Ignore Report Quick Reply

Always got it in x-ray proof mylar, never missed an order. I bought it locally most of the time tho, met a bloke off craigslist who would do $50 grams
Sophie Naddlegold - Thu, 23 Mar 2017 22:59:53 EST ID:uPjbLXXg No.575736 Ignore Report Quick Reply

Glad you understand, I always had my mind blown by how cheap drugs are in America (I'm Australian) but a big part of it is because the drugs are half to a quarter of the strength of shit here, so the price balances out to not be too much more expensive than some US states. On the streets here heroin costs $50-100 a point, and that's going to be lesser quality than the pure H I get, street H here seems to be about 25-50% heroin or more. Being so close to South-East Asia helps a lot, they're the kings of opioids IMO, they shit on the cartels and arabs when it comes to quality. Love getting my pure white rock hard chunks of H, sometimes its hard to split it off even with a knife, then it dissolves in cold water without a trace after a few seconds of stirring. Perfect.

Rambling aside, a handy thing I've found is that if you're mixing heroin and U4, you can use the U4 to dissolve brown heroin if you mix them together in a shot. Hopefully this will help with the caustic nature of U4 but I doubt it.

Constipation by Charlotte Trotwill - Tue, 21 Mar 2017 15:21:16 EST ID:yTe5eWLU No.575598 Ignore Report Reply Quick Reply
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How the hell do you guys deal with the constipation after opiate use??

Just now i had to use my fingers to help pull out the largest rock solid turd that ive seen in my life, it was bone dry and not moving by itself. That is something i never want to do again EVER. There was blood and everything.

Do i quit now or can i avoid this
2 posts omitted. Click Reply to view.
Cedric Wigglefock - Wed, 22 Mar 2017 08:08:38 EST ID:WwVH4V0W No.575627 Ignore Report Quick Reply
Idk about the magnesium shit OP, but I've never had a problem with constipation on opiates. I just try to drink a ton of water and eat lots of veggies and less meat and I tend to have a normal bowel movement every day or two. Laxatives should be on hand too for any opi user.
Nell Bugglestick - Wed, 22 Mar 2017 09:45:22 EST ID:XuZlb/9s No.575631 Ignore Report Quick Reply
From Wikipedia:
>Magnesium citrate is used medicinally as a saline laxative and to completely empty the bowel prior to a major surgery or colonoscopy

If surgeons rely on it, I think it's a good bet it's effective.
driven !FTPgBqDDy. - Wed, 22 Mar 2017 14:35:39 EST ID:xB/1eYGi No.575638 Ignore Report Quick Reply
magnesium and water for softening. cigarettes and coffee to induce bowel movement
James Worthingstone - Wed, 22 Mar 2017 15:01:26 EST ID:rdbflkGd No.575643 Ignore Report Quick Reply
Magnesium Citrate was the only thing that allowed me to shit while on Zubsolv in rehab. (Better version of suboxone imo) Lately my post-binge shits are like deer turds, round, hard, and painful. I have had to deal with boulders though, and that's fucking torture. After those I always made sure to take some kind of softener for binges.
WIAKR+Pa - Thu, 23 Mar 2017 18:44:48 EST ID:5sjIFbHK No.575722 Ignore Report Quick Reply
Personally, once I level off my dose and maintain it for say... Two months, at that point my body is able to have adjusted all of its digestion biochemistry, and I'll start to have mostly regular movements again. So, if you're able to stay at the same dose for a good while, that's a way to regulate everything without any supplements, enemas, or anything like that. YMMV.

Tips for first time users heroin by Isabella Gezzleshit - Tue, 21 Mar 2017 18:35:31 EST ID:eMO6AFiU No.575607 Ignore Report Reply Quick Reply
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Hey guys,

I'm going to use heroin for the first time soon, would really like to have a few questions answered.

What dose would you guys advise for a first timer? I'm almost 7 feet tall, so i guess that should be taken into account.

After some time lurking here i read that shooting up is something people usually do when they start developing a tolerence to the drug, so a first timer shouldn't really bother, did i get that right? I'm really curious about shooting up, and would really like to try it atleast once in my life, but it's not a must. So i guess smoking it would my best bet?

I'm not really worried about addiction, i'm pretty responsible with drugs and never really gotten adicted to anything apart from cigerettes.

Any other tips would also be appreciated, so please share.
23 posts and 4 images omitted. Click Reply to view.
Derluft !oCyNK.1Qtc - Thu, 23 Mar 2017 13:59:07 EST ID:TIEC4Hy6 No.575697 Ignore Report Quick Reply
What do you mean by "...I hope you. . .to make a change in your behavior;" you mean junkie behavior, addicted behavior or what? - If I may ask, what is "junkie level?"
As I have not stolen from another sole, for my addiction, in the seven years that I have been, I'm intrigued by your umbrella​'d perception for addiction.
Frederick Collerbotch - Thu, 23 Mar 2017 14:43:13 EST ID:rdbflkGd No.575698 Ignore Report Quick Reply
>This guy is excited to try heroin

Oh boy, you're in for a treat. Enjoy losing everything you own eventually, including your will to live.
Isabella Sabblespear - Thu, 23 Mar 2017 15:04:36 EST ID:UCBssEMB No.575701 Ignore Report Quick Reply
Dont spoil the surprise, man
Dr. Mario !gWLn19/oKs - Thu, 23 Mar 2017 15:47:12 EST ID:NZSaVF2M No.575703 Ignore Report Quick Reply
It's U44 bro.


Sorry the license plate that said BTHU47 that didn't belong to me was outside my control to correct.

It's a fair thing to say. Whether you believe me or not I'm 90% sure I typed U44 in that post and my dumbrella ass phone autocorrect it to U47. I have to do this stupid af combo of space bar and deletions to fix an autocorrect.

So sorry about triggering you.
Dr. Mario !gWLn19/oKs - Thu, 23 Mar 2017 15:51:26 EST ID:NZSaVF2M No.575705 Ignore Report Quick Reply
See look it autocorrected it my second time using it in that post.


If I could edit it I would leave the photo but correct the spelling. Statistically it's still a funny anomaly. Think about it BTHU47 was the perfect one. What other number would keep it recognizable? Anything but another 4 or maybe arguably a 0 would have not worked lmao. The set setting and time context when seeing that plate was funny af.

Does DXM block kratom? by Reuben Serringhood - Tue, 21 Mar 2017 17:07:14 EST ID:FVdRSp2i No.575604 Ignore Report Reply Quick Reply
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Does DXM block kratom? I took a first plateau dose last night, and then took some kratom about two hours in. I didn't feel the kratom at all, and I got horrible RLS.
5 posts omitted. Click Reply to view.
Alice Punninghadge - Wed, 22 Mar 2017 09:34:26 EST ID:VOAfdbYu No.575630 Ignore Report Quick Reply
DXM is a much stronger drug, and will probably just dominate the effects you feel.
driven !FTPgBqDDy. - Wed, 22 Mar 2017 14:38:31 EST ID:xB/1eYGi No.575639 Ignore Report Quick Reply
Certain compounds in Kratom act on norepinephrine and NMDA receptors. It's kind of akin to taking tramadol with DXM
Dr. Mario !gWLn19/oKs - Wed, 22 Mar 2017 18:46:19 EST ID:NZSaVF2M No.575650 Ignore Report Quick Reply
My euphoria levels absolutely tanked after a solid month of not dosing 30 or 45mg DXM 30-45mins before my dose. I was religious about it.

Well after that (4-8 weeks without DXM use and similar opi dosages) it was like DXM didn't do shit any more.

I assume it's because it doesn't lower tolerance; it partially reduces tolerance increase as you said, that's it.
Esther Duckway - Thu, 23 Mar 2017 02:43:04 EST ID:FVdRSp2i No.575670 Ignore Report Quick Reply
what's taking tram with dxm like?
overgrownpath !3g9OJxiR.6 - Thu, 23 Mar 2017 02:46:19 EST ID:xqj8DQup No.575671 Ignore Report Quick Reply
feels like serotonin syndrome

Buprenorphine when used intranasaly by Ian Wivingville - Wed, 22 Mar 2017 20:20:21 EST ID:B2oX/1Bd No.575655 Ignore Report Reply Quick Reply
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Having trouble googling when snorted suboxone's (actually pure buprenorphine) onset is? what about its peak?
Aciddrop !tbcTsdGo8Q!!vVWR8L52 - Wed, 22 Mar 2017 20:45:47 EST ID:j4aMZlxF No.575657 Ignore Report Quick Reply
The onset starts at about 15 min and the high peaks at 1.5-2 hours.

Heroin Vacation by Kingdope77 - Tue, 21 Mar 2017 12:43:09 EST ID:5FQVXlmS No.575596 Ignore Report Reply Quick Reply
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Hey can anyone link me the post or answer to which country is the best to vacation to for the cheapest, most potent, and safe place to buy Heroin. I've heard Cambodia and some others...???
1 posts omitted. Click Reply to view.
overgrownpath !3g9OJxiR.6 - Wed, 22 Mar 2017 05:36:39 EST ID:W5gIGXZi No.575621 Ignore Report Quick Reply
I've heard southeast asia in general (thailand, vietnam, cambodia, etc) isn't too bad for scoring decent heroin. While you do need to have at least a bit of bravado and street sense if only because of the particularly draconian punishments for drug 'crime' in those countries (capital punishment included), they are still very corrupt and you can bribe your way around most legal issues you may be unlucky enough to become involved in. I know that in Thailand for example there's a well-known tourist 'trail' where you get taken into a mountain village in the north of the country and smoke opium with a local villager(s). It goes without saying that the drugs are dirt cheap and the opiates are often great quality. My buddy nz knows much more about this area in regards to opiates than me so I'll get him to post about it for you - I know that he rather easily scored heroin multiple times in Thailand. You also get the bonus of over the counter benzos in these countries too - imagine getting a massive bag of 2mg xanax legally and then doing a fat shot from a gram of china white you bought for $50 USD.
overgrownpath !3g9OJxiR.6 - Wed, 22 Mar 2017 05:41:52 EST ID:W5gIGXZi No.575622 Ignore Report Quick Reply
just stay away from the Philippines. lawdy, that Duterte is a certified piece of shit. but it's really crazy/sad how being just an average or even a working class Westerner means you're automatically a rich person in Southeast Asia.
Kingdope77 - Wed, 22 Mar 2017 12:17:31 EST ID:5FQVXlmS No.575634 Ignore Report Quick Reply
>>575621 thank you sir
Archie Buzzfoot - Wed, 22 Mar 2017 12:25:53 EST ID:oaWRMjn3 No.575635 Ignore Report Quick Reply

Rodrigo "inject drugs? Eat some slugs" duterte will welcome you with open arms
Nathaniel Bungerridge - Fri, 24 Mar 2017 02:26:28 EST ID:Mjy+WWFm No.575750 Ignore Report Quick Reply
OP, check out the old guidebook, can be found pirate eBook PDF format somewhere, "Heroin Cultivation in Southeast Asia".
Not only does it give good detail all the way from poppies to punctures (heroin in veins... starts with a 'p'), but for your needs, I bet the intro chapter lists what countries the researchers visited several score ago to get the info.

tldr: goldren triangle?

or for brown stuff: turkey, or afhanghistan (but then u get blown up by terorrist)

Memories by Hamilton Dinkinfitch - Wed, 22 Mar 2017 07:11:33 EST ID:Mjy+WWFm No.575624 Ignore Report Reply Quick Reply
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Isn't it cool how closed-eye reflection/meditation can cause really old memories to spring up out of nowhere?
For instance I just had the detailed face of an old, old acquaintance pop up, and I still can't even remember his name!

Speculation time:
So the only other method afaik of memory retrieval is hypnosis. I'd like to catch both under an fMRI and see how similar their activity is.
Cedric Wigglefock - Wed, 22 Mar 2017 07:55:30 EST ID:WwVH4V0W No.575625 Ignore Report Quick Reply
This is interesting OP, and I appreciate your concision, however it isn't relevant to /opi/ at all. I'll fix it for you so it doesn't get locked.

>Isn't it cool how closed-eye reflection/meditation can cause really old memories to spring up out of nowhere when you're on opiates?
>For instance I just had the detailed face of an old, old acquaintance pop up, and I still can't even remember his name (and I'm nodding right now)!

>Speculation time:
>So the only other method afaik of memory retrieval is hypnosis. I'd like to catch both under an fMRI and see how similar their activity is.

Shooting for the first time by Phineas Gogglehall - Tue, 14 Mar 2017 13:35:41 EST ID:HwXAMd+P No.575313 Ignore Report Reply Quick Reply
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So i am no noob to opiates but recently I have been kicking around the idea of shooting up. I have watched my brother do prep on dope and I have a solid connection for now. There is a slight problem of getting spikes. I never bought them before and I'm not sure what to ask for. I could probably get one from my dealer but that isn't the biggest problem. Should I even do it? I snort a bag or 2 right now and feel great. Right now I don't have a lot of money but enough to keep me in booze and pizza regularly. I only do dope 2 days at a time with at least 3 days inbetween sessions. for example I snorted three bags over a 6 hour period and woke up feeling glorious with another bag to spare. I don't want to lose that but I also want the "rush" I hear people talk about. Idk

> should I shoot up
> what do I ask the pharmacist for? (gauge or whatever)
>FYI I'm a big guy with no real easy to hit viens except on my hands. What are the best places to shoot?
> Thanks /opi/
10 posts and 3 images omitted. Click Reply to view.
Martin Brenkinstug - Sun, 19 Mar 2017 17:11:38 EST ID:xFzc/Lq3 No.575525 Ignore Report Quick Reply
Hello and good luck

A few pointers: the only rush should be the one you feel after pulling out the now empty rig...

Fishing around with used rigs is how you get all tracked up. New shot new needle. Period.

Choose a safe time and place. That bathroom stall is great and that one toilet locking bathroom is tops. Just dont linger. Shoot and move fam. Ditch the old rig.

When a fellow iv user warns you of strength, it very well could be a hustle if theyre supplying or your middleman. It could also be the warning that saves your life. Always doing test shots with new dope so you know, you can always do more. The opposite is tragically untrue.

Heres a really random one: drink plenty of water. This will make veins less of a challenge.

Tie it, slap it, flex and release. And learn to be steady.
Comment too long. Click here to view the full text.
Phyllis Nickleworth - Mon, 20 Mar 2017 10:14:50 EST ID:iLT0Kb2o No.575551 Ignore Report Quick Reply
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i taught myself after someone missed two shots in my arm and now i have scars because of it. I noticed after taking the initiative and learning myself, I have never missed because I learned how to actually do it correctly, instead of listening to some ego inflated junkie tell me how its 'spose to be
Simon Brendlechore - Mon, 20 Mar 2017 15:48:40 EST ID:oaWRMjn3 No.575563 Ignore Report Quick Reply

Wow bro I bet you're like really smart, how did you do it? Was it scary?
Fuck Cleffingworth - Tue, 21 Mar 2017 10:56:13 EST ID:qvwUq5Mr No.575592 Ignore Report Quick Reply
Good choice. Don't shoot up. It'll make dope go from a fun thing to a bad thing. I've always snorted it. Keep on tootin' OP.
br4ce - Tue, 21 Mar 2017 19:24:04 EST ID:t4c31Idi No.575608 Ignore Report Quick Reply
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My intelligence is irrelevant. I bought a fresh pack of needles, cleaned the area of injection, very slowly moved the needle forward until I felt a second sensation that indicated I broke through the wall of the vein, pulled back upon the plunger and struck crimson gold. The act of doing it myself also lessened the unpleasant situations, personally. I know my last post probably came off a little stuck up, but the amount of users I have met that are exceptionally hard headed regarding the absolute divine nature of their opinion is just repulsive. If someone has a better way of doing something or knows more about a given subject then I want to follow their lead instead of continuing the bliss enshrouded by my ignorance's technique.

Again by Basil Clushfutch - Wed, 08 Mar 2017 20:19:17 EST ID:86FbtCXB No.575053 Ignore Report Reply Quick Reply
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If you could start over again, go back in time to where you first tried oppiates and stop yourself, would you?

Or has it all been worth it?
25 posts and 7 images omitted. Click Reply to view.
nz !!vVWR8L52 - Tue, 14 Mar 2017 21:53:48 EST ID:JvUiiflM No.575330 Ignore Report Quick Reply
Yeah just added an extra z. THough there was a trip here who posted under nzz. Just mine with an extra z. But he's been dead a while now.

afaik I just typed my own trip? I don't get that one.
Vehk !7HYGxe5v5c - Tue, 14 Mar 2017 22:41:29 EST ID:bvn43anT No.575336 Ignore Report Quick Reply
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If I could go back in time, I would tell my younger self to:

  • Never take MDMA. The empathetic emotions you feel are a contrived falsehood, and out of all the drugs I took I think it's the one that most damaged my attention span.
  • Don't smoke weed every day (I wasted about two years of my life in a total blur from this)
  • Don't start using amphetamine powder and research stimulants, but solely restrict yourself to pharmaceutical stimulants where you are forced by financial constraints to work within reasonable doses and usage periods.
  • Don't steal pills from your relatives, you parasite. There'll be a time when you have money and means to acquire them for yourself without dishonouring your bonds with those people by surreptitiousness.

As for opiates, I would do it all again because it has never affected my life and self esteem in anything except a positive way. The only guilt I have ever felt from using opiates was an internalisation of the stigma present in society into the sensation that what I was doing was wrong, even if it was harmless to me and well monitored. When I look at news articles about needles being found and see people talking about stomping and killing "junkies", or hear people on the radio talking about annihilating "heroin vermin" without anyone stopping to contradict them, it made me feel bad. I have had negative consequences in my life from every other drug but opiates - for them, it was only the horrible reproaches of a society caught up in a bizarre demonstration of macho posturing.
sinister !1yH/qSM.uA - Sun, 19 Mar 2017 03:37:44 EST ID:FfRjrkpe No.575505 Ignore Report Quick Reply
do you have any idea what went down there? like my ex used to talk to him a bit and apparently he was out for a walk and died suspiciously, but not suicide or OD. thats all i know.
overgrownpath !3g9OJxiR.6 - Sun, 19 Mar 2017 05:28:08 EST ID:W5gIGXZi No.575507 Ignore Report Quick Reply
no, he OD'd from drinking + benzos afaik
nz !!vVWR8L52 - Tue, 21 Mar 2017 10:41:26 EST ID:W5gIGXZi No.575590 Ignore Report Quick Reply
His family is just ashamed.

Kratom withdrawal by Mushroom-Madness - Wed, 15 Mar 2017 17:52:53 EST ID:rPgCMxeO No.575360 Ignore Report Reply Quick Reply
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How long does the diarrhea last with kratom withdrawal?
It has been 25 days for me without kratom so far. I did take l-theanine for the last week in pretty high doses, but I quit that the day before yesterday.
Coconut !hEpdoZ.tHU - Mon, 20 Mar 2017 19:32:27 EST ID:eD0EfubV No.575567 Ignore Report Quick Reply
Don't much like quitters, son.

Kratom gives me little withdrawals but as far as diarrhea goes I only get it for like 3 days tops and that's only when shipping is late.

Snorting Suboxone Strips Problem by Ebenezer Brettingspear - Fri, 17 Mar 2017 11:56:56 EST ID:6mCiPIl/ No.575428 Ignore Report Reply Quick Reply
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Question, what can go wrong with continuously snorting suboxone strips. I remember in rehab a guy said he blew his nose and his septum came out from snorting too much cocaine. Ive been snorting a quarter of a strip everyday for about 8 months. Just recently I have this weird scab /booger on the fleshy part on the inside but not the septum right by the entrance (even though no substance touches it, unless it drips?(but it goes down the back so idk)) And now its getting bigger going up towards the nostril. And it looks like my septum is a little thinner but then again idk because I dont look at it.

Also I assume its bad for your lungs and theyve been hurting too.

Regardless im cutting back (mainly just to get off the shit as i dont even feel anything but a barely little lift for 1 hour followed by 10 hours of feeling a little odd (I assume because of the naloxone/drug in itself probably should just take them sublingually like im supposed to. I think the BA is something like 10% less? But with this nose problem its a little bit more of a motivator, but addicts gunna addict. I could get high off them if I just took em once every 2 weeks or so.
And dont mention IV as I was doin that for almost a uear and that fucked my veins up exponentially. And probably has caused long term health problems yet to show. Not opposed to rectally but as im always constipated because of the drug its a no go unless I cold turkey for a few days, which is hard to do with the sheer boredom of my life.

Any advice/info greatly appreciated.
Suboxone is relatively new maybe less than ~40? Years so nobody really knows the long term effects and could end up causing voracious cancers. Who knows. ....
3 posts omitted. Click Reply to view.
someone who is not me wants to jump off suboxone - Sun, 19 Mar 2017 07:31:04 EST ID:k60BOOUh No.575511 Ignore Report Quick Reply
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this is offtopic but i will just post here because i want to avoid making a new thread:

hypothetically: my friend wants to jump off suboxone mainly for financial reasons.. but my friend hasnt weened down very far.. they've been taking 2-4mg a day.. but today is the first day they have tried taking only 1mg and they already feel mild-moderate withdrawals and also the brainshocks that accompany ssri dsicontinuation.

allegedly: They only have about 600 dollars for the next two months including food so they feel like they dont want to spend money on more drugs but they could probably buy another suboxone or two.. also right now they have about 10 days free from work so time is a factor.

supposedly: Currently the only opiates they have left are 3mg of suboxone and 96mg of lope and 1kg of very mild and heavily washed poppy seeds.. also some lexapro to help with brainshocks.. also they could possibly buy some gabagernic drugs to ease off but my friend says that gaba drugs give him slight hangover feelings even with just one use..

my question is will the withdrawals be too severe to the point where they should spend another week or so weening down or will the low quality opiates they have left be enough to do a super fast taper and jump completely off? The goal is to be opiate naive in about 7-14 days.
James Sublinghood - Sun, 19 Mar 2017 09:37:27 EST ID:+0xUKj+s No.575517 Ignore Report Quick Reply
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>my friend
Oh come off it.

>brainshocks that accompany SSRI discontinuation
..Why? Bupe has no apprec.iable affinity for SERT

>the goal is to be opiate naive

I don't think you understand what that means. There is no going back. I'm going to assume you mean that that goal is to be non-dependent.

Your best bet, I mean... uh, your 'friend's' best bet is probably to see how well they can get by with loperamide alone and tough things out, the seeds will only complicate things and risk precipitated WDs, and if they're washed anyway probably not even worth bothering with. Youl could also try controlling most symptoms with lop and then adding a tiny bit of bupe on top, but if you want to get it done ASAP then go with lop alone. The lexapro is useless.
If you can get pregablin that stuff is great for WDs.
Reuben Nillerfuck - Mon, 20 Mar 2017 05:44:55 EST ID:k60BOOUh No.575544 Ignore Report Quick Reply
>Bupe has no apprec.iable affinity for SERT



Nigel Sashhood - Mon, 20 Mar 2017 09:24:46 EST ID:+0xUKj+s No.575549 Ignore Report Quick Reply
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Thanks that's very interesting.

Being more specific though, SERT = serotonin transporter and I'm still yet to see anything suggesting that bupe effects it (I couldn't read that medscape article though).That doesn't mean that it doesn't have serotonergic action though, just that it's not an SRI.
The article on the antidepressant effects specifically says that they're due to its kappa antagonism, whether that has a downstream effect on serotonin levels though I don't know.
I can say too that I've never gotten brain zaps like from stopping SSRI/SNRIs from bupe WDs. That doesn't mean it couldn't happen though.
The potential for SS is definitely something for me to keep in mind what with being on stupid amounts of bupe, mirtazapine and loving DXM as much as I do.
Reuben Nillerfuck - Mon, 20 Mar 2017 14:01:38 EST ID:k60BOOUh No.575560 Ignore Report Quick Reply
i suppose you are right.. i always thought the action was akin to tramadol or some of those weird stony feelings you get from the full spectrum of opiates in PST

i have heard of brain shocks coming from bupe cessation for what it is worth

Heroin withdrawal too easy? by Hedda Cuckleheck - Sun, 19 Mar 2017 04:59:00 EST ID:ShtrbOue No.575506 Ignore Report Reply Quick Reply
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I'm wondering if anyone else has had this sort of experience.
I've quit heroin (250mg IV daily habit, 6 months) for financial and social reasons and I'm currently just waking up... to day 3.
Everything I've seen online, every other persons experience has supposedly been pure hell. I've found it... easy so far.
Day 1 was awful of course, chills sweats and all over muscle restlessness that was torture, the night was too. Day 2 was pretty bad until about 40 hours in, then all the worst symptoms seemed to go away! I was listening to music dancing and jumping around my room feeling great and almost manic, I even enjoyed a few whiskeys, something I would never have dreamed of on day 2. I slept mostly, in couple hour stints throughout the night.
Now the start of day 3, I feel a little chilly and slightly nauseous but that's it. I've not had diarrhoea, I've not vomited, I've barely even had cravings... I feel like the withdrawals are coming to and end! What's going on! I'm not complaining but I'm confused and a little worried there may be some... delayed symptoms.
All I've had to ease symptoms is lope, xanax and a few pregabalin, normal doses.

Maybe it's something to do with my physiology. I'm curious if anyone else goes through full blown cold turkey withdrawal this easily? Any input is greatly appreciated.
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James Sublinghood - Sun, 19 Mar 2017 09:20:36 EST ID:+0xUKj+s No.575516 Ignore Report Quick Reply
>All I've had to ease symptoms is lope, xanax and a few pregabalin

Loperamide and pregabalin (combined, pregabalin especially) are like fucking magic for withdrawals.

>I suppose the hard part is going to be the long mental grind in the months to come

Yep, acute WD symptoms are the easy part really
Jarvis Murdham - Sun, 19 Mar 2017 13:46:48 EST ID:H8RIJymP No.575522 Ignore Report Quick Reply
Albert Blemmerchug - Sun, 19 Mar 2017 19:29:33 EST ID:okQMHw2O No.575530 Ignore Report Quick Reply
Acute withdrawal can sometimes be just that. Anyone can dry out. Getting clean can be the fight of your life
Nigel Sashhood - Sun, 19 Mar 2017 20:56:48 EST ID:+0xUKj+s No.575536 Ignore Report Quick Reply
>Day 2 was pretty bad until about 40 hours in

... so until the end of day 3?
couldn't help myself
Lillian Tootville - Mon, 20 Mar 2017 12:36:18 EST ID:76DuEQ0D No.575558 Ignore Report Quick Reply
as someone who has gone through both benzo withdrawal and opiate withdrawal, i can confidently say opiate withdrawal is a walk in the park compared to benzo withdrawal. opiate withdrawal just sucks profoundly hard. benzo withdrawal is like a nightmare you can't wake up from. and seizures.

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