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Di-acetyl-bupe-acetamide or tri-acetyl-bupe by Q !57aon8jsJ2 - Fri, 19 May 2017 02:51:58 EST ID:ztWD2hgP No.578645 Ignore Report Quick Reply
File: 1495176718263.jpg -(45379B / 44.32KB, 500x333) Thumbnail displayed, click image for full size. 45379
If you check the BWN i posted i found a new way to make a few opi analogs and in this thread ill be teaching how to apply my method to buprenorphine which makes it roughly 2-4x more potent and also seems to make it into either a full agonist or something because it adds an insane rush, crazy euphoria, and full agonist like nods. The rush was so strong i had to push my shot insanely slow to avoid vomiting and or just falling out the rush was that strong and it lasted a full hour with residual opi stimulation for another 2-4 hours and then tapering down to hardcore sedation and mad narcoleptic nods.

Ill post pictures and step by step instructions post by post. Im starting now and will post as i go.
Reuben Gangerdet - Fri, 19 May 2017 05:08:57 EST ID:9uzRSC0V No.578647 Ignore Report Quick Reply
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f5 f5 f5 f5 f5
Q !57aon8jsJ2 - Fri, 19 May 2017 05:28:41 EST ID:ztWD2hgP No.578648 Ignore Report Quick Reply
1495186121204.jpg -(1777537B / 1.70MB, 3264x1836) Thumbnail displayed, click image for full size.
Done. Most of the posts will be pics with brief details.

This is the sodium acetate which is the catalyst that lets this work. You can make this easily by combining excess GAA or AA with sodium carb or bicarb then heating at about 280-300 F until there is no smell and it seems completely dry and powdery. Start with an oven or toaster oven then when it start to have a very low moisture content you can use the microwave to finish it.
Q !57aon8jsJ2 - Fri, 19 May 2017 05:33:55 EST ID:ztWD2hgP No.578649 Ignore Report Quick Reply
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next place your cooking vessel on a heat source hot enough to ensure zero water is on the vessel and leave it there until it is extremely hot. once you do that you will be adding the sodium acetate to the vessel while it it is still hot but after removing it from the heat source.
Q !57aon8jsJ2 - Fri, 19 May 2017 05:36:14 EST ID:ztWD2hgP No.578650 Ignore Report Quick Reply
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this is the amount i used but im still determining the ideal amount. That spoon is insanely hot btw
Q !57aon8jsJ2 - Fri, 19 May 2017 05:40:01 EST ID:ztWD2hgP No.578651 Ignore Report Quick Reply
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sorry amount of sodium acetate.

Next you will add the AA or GAA and it will stink, the sodium acetate cause some excess gaseous acetic acid to form but just dont sit and breath it. You are going to be filling the spoon with the gaa or aa which is a shit load but this reaction relies on excess free acetyls.
Q !57aon8jsJ2 - Fri, 19 May 2017 05:43:21 EST ID:ztWD2hgP No.578652 Ignore Report Quick Reply
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this is the hot spoon full of GAA on top of the sodium acetate. Please note ONLY 99% GAA or AA will work for this not 97-98% GAA.
Q !57aon8jsJ2 - Fri, 19 May 2017 05:46:38 EST ID:ztWD2hgP No.578653 Ignore Report Quick Reply
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The combination of heat from the spoon and the exothermic reaction between the Na-acetate and GAA mean you need to add the buprenorphine now and it will instantly begin reacting. this is a 4 mg strip.
Q !57aon8jsJ2 - Fri, 19 May 2017 05:49:38 EST ID:ztWD2hgP No.578655 Ignore Report Quick Reply
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next set the elec stove to about this heat close-ish is fine. and then you will place the spoon back on the burner, until all the liquid is evaped or nearly evaped.
Q !57aon8jsJ2 - Fri, 19 May 2017 05:52:00 EST ID:ztWD2hgP No.578656 Ignore Report Quick Reply
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itll look a little more dry than this when its evapped, at which point remove from heat and set aside for next step.
Q !57aon8jsJ2 - Fri, 19 May 2017 05:54:46 EST ID:ztWD2hgP No.578657 Ignore Report Quick Reply
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then add a tiny bit more sodium acetate like a small fraction of the amount u used originally and top the spoon off with more GAA.
Q !57aon8jsJ2 - Fri, 19 May 2017 05:56:34 EST ID:ztWD2hgP No.578658 Ignore Report Quick Reply
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next heat to a light boil until it looks about like this.
Q !57aon8jsJ2 - Fri, 19 May 2017 05:58:56 EST ID:ztWD2hgP No.578659 Ignore Report Quick Reply
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Since i was making an 8 mg dose ill just continue through to show how to make a stronger dose. Next add the next strip while the GAA is still boiling and let dissolve.
Q !57aon8jsJ2 - Fri, 19 May 2017 06:01:21 EST ID:ztWD2hgP No.578660 Ignore Report Quick Reply
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It will start to use up all the GAA at this point so adding a few more drops is a must. This will cause it to instantly boil and react heavily.
Q !57aon8jsJ2 - Fri, 19 May 2017 06:04:11 EST ID:ztWD2hgP No.578661 Ignore Report Quick Reply
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thats what it looks like just before it starts to burn this is when it needs more GAA right away. After it boils it will look a bit like this
Q !57aon8jsJ2 - Fri, 19 May 2017 06:07:08 EST ID:ztWD2hgP No.578663 Ignore Report Quick Reply
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one more tiny splash of gaa and then letting that evaporate will leave you with something like this.
Q !57aon8jsJ2 - Fri, 19 May 2017 06:09:12 EST ID:ztWD2hgP No.578664 Ignore Report Quick Reply
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after that remove from heat and very slowly drop by drop add water until the spoon is half full.
Q !57aon8jsJ2 - Fri, 19 May 2017 06:11:42 EST ID:ztWD2hgP No.578665 Ignore Report Quick Reply
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next just using not too much heat evap the water to near dryness and repeat that process two or three times, making sure to stir the water and drugs while they dry.
Q !57aon8jsJ2 - Fri, 19 May 2017 06:13:33 EST ID:ztWD2hgP No.578666 Ignore Report Quick Reply
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second water evap
Q !57aon8jsJ2 - Fri, 19 May 2017 06:16:08 EST ID:ztWD2hgP No.578667 Ignore Report Quick Reply
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third water evap after vigorous stirring
Q !57aon8jsJ2 - Fri, 19 May 2017 06:21:03 EST ID:ztWD2hgP No.578668 Ignore Report Quick Reply
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That is exactly the outcome you are looking for when its ready to be finished. It turns almost a muddy brown red with obvious cloudiness, this is good and it should always do this eventually. one final more gentle evap with careful stirring causes it to change to its final form and ill post the last few pics of it changing.
Q !57aon8jsJ2 - Fri, 19 May 2017 06:22:42 EST ID:ztWD2hgP No.578669 Ignore Report Quick Reply
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the last reaction before its complete and ready to be watered down and filtered well for use
Q !57aon8jsJ2 - Fri, 19 May 2017 06:24:25 EST ID:ztWD2hgP No.578670 Ignore Report Quick Reply
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once it cools down those lighter spots on top dissipate. last image before the final product
Q !57aon8jsJ2 - Fri, 19 May 2017 06:27:01 EST ID:ztWD2hgP No.578672 Ignore Report Quick Reply
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once cooled it turns a shade between milky red brown and dark brown red. Be sure to dilute however much u make. i made 8 mg and thats gonna be 2-4 hits for me.
Q !57aon8jsJ2 - Fri, 19 May 2017 06:33:51 EST ID:ztWD2hgP No.578673 Ignore Report Quick Reply
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This is the full shot after dilution, adding hexen and nep and adding clonazolam, and after filtering well twice. I kept 1.5 ml in the rig for use now as my hit for the night and am saving the other 1.5 ml.

This shit is strong as fuck guys, be extremely careful. Seriously i shot 4 mg and had to push so insanely slow because even an average speed shot had me feeling like i was going to black out instantly, had to slow down to like a super gradual infusion and even then the rush was nuts lasted an hour and i nearly threw up while i was injecting.
Q !57aon8jsJ2 - Fri, 19 May 2017 06:36:45 EST ID:ztWD2hgP No.578675 Ignore Report Quick Reply
Thats all folks. I hope you found this to be an interesting and educational thread. As a side note this process of GAA+sodium acetate can also be used to selectively synthesize 6-mono-acetyl-morphine from morphine, not heroin but it will work for pure 6-mam.
Hunter S. Nodson - Fri, 19 May 2017 10:16:18 EST ID:a1WEtajM No.578684 Ignore Report Quick Reply

what would the difference between using sodium hydroxide be compared to your method to get 6-MAM? Once I get my poppy seeds I'm thinking of trying to turn it from morphine to that and thats all I'll have access to. I'm guessing I'd have to have some purified product before even attempting though.

triple6tittyfucker is my steam btw
Q !57aon8jsJ2 - Fri, 19 May 2017 13:03:08 EST ID:ztWD2hgP No.578695 Ignore Report Quick Reply
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I made one more batch because i slightly overheated (not ruined just damaged) that last batch, doing 2 strips at once is like 4x harder for some reason than doing each strip one at a time. All the steps are the same though. This is just a reference pic for how one 4/1 mg suboxone strip should look if the reaction runs perfect. Meaning you figured out the exact temp for each step, what is added when in each step, the strip fully reacted very quickly, and then was dried rapidly until it starts to look dry/crusty/almost oily and as soon as any of the now just VERY hot but mostly done reacting bupe left in the vessel develops any even slightly dark orange color remove the vessel from the heat immediately and assuming its a metal vessel like a spoon have a shallow puddle of cold water on a plate ready for you and just carefully only touch the bottom of the spoon to to the cold water, and youll probs want to do the same thing to whatever very back edge of the spoon you are using to hold it, just so it doesnt burn you, make sure to have a pot holder that you cab easily manipulate delicately enough to carry smaaall amounts of valuable liquid. Trust me the worst is finishing the reaction and being all ready to quench the reaction with water and grabbing the spoon only to scald the shit outa your fingers and spill the shit or pick it up carefully with a square pot holder only to have the spoon flip over or spin as you try to pick it up by the sides or anywhere else you could grip it.


The reason this works, and why its such an amazing technique that i simply rediscovered after days of research is HUGE. This same technique or this with a few extra steps additions or changes can be used to acetylate a huge number of opis. However it can not be used to di-acetylate anything that is a 3-6 hydroxy morphinan. It can di-acetylate just not in that way.
Q !57aon8jsJ2 - Fri, 19 May 2017 14:54:01 EST ID:ztWD2hgP No.578705 Ignore Report Quick Reply
Presumably the naloxone is also being partly acetylated but it doesnt seem to have any effect on the antagonism. In fact this shit feels almost exactly like a full agonist when IVd. Plus its using way less of the acetyls generated since its 4 mg bupe 1 mg naloxone.
Caroline Tootfuck - Fri, 19 May 2017 21:29:03 EST ID:9uzRSC0V No.578716 Ignore Report Quick Reply
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love u q, cant wait to try this.
if i use 8mg pills, should i just filter through cotton then use as you do the strip here?
how long do they last?
what do they feel like (especially without stims+benz in the rig)?
any other bonus facts appreciated
Q !57aon8jsJ2 - Fri, 19 May 2017 22:41:46 EST ID:ztWD2hgP No.578725 Ignore Report Quick Reply
hmmm for pills crush them finely first ubtil they are just dust then add the pill powder to the hot GAA or AA + and Na-acetate. filter everything out at the end, you should try both though but i think filtering it first will cause waste and could add too much water to the reaction which ruins it Other step should be the same.

On its own, The rush is slow at first but then hits u like a fucking train. The potency seems about 2-3X that of plain bupe. The rush comes on slow at first then builds into a great euphoric energy boost which lasts a little while and then rapidly gives way to very heavy full body morphine like sedation. Mental euphoria is good but not incredible however the body high is amazing. The nods are amazing as well and on top the sedation the create a wonderful synergy of perfect relaxation on the verge of a nap but instead u get those perfect short but deep and full nods.

JUST FYI to everybody this is just the first thread ill be making, I have at least 2 maybe as many as 5 in the pipeline. Plus analogs of a few other things that i may make.
Eugene Dunningbury - Sat, 20 May 2017 20:31:53 EST ID:azIOO0W0 No.578749 Ignore Report Quick Reply

Surely you can come up with something better than a spoon to do this in. Also why do you keep adding more GAA and sodium acetate after the initial reaction? Seems excessive for just 4-8mg of buprenorphine to be honest.

And holy fuck that looks janky as a motherfucker. I would not IV that shit if my life depended on it lol.

Interesting thread, though. I just wish you went into a little more detail in the steps and why they're necessary. Also some sources would be nice. Keep 'em coming, though!
MDCB !txtI0IGNgk!!VyqqkppB - Thu, 01 Jun 2017 03:49:44 EST ID:kF/r7AF2 No.579559 Ignore Report Quick Reply
This was about to die.
Someonw screencap pls.
Q !57aon8jsJ2 - Thu, 01 Jun 2017 13:58:18 EST ID:ztWD2hgP No.579581 Ignore Report Quick Reply
Of course i can use something else the reason i use a spoon is that i can run the reaction very quickly in a spoon with out burning it. The excess GAA and sodium acetate is in part because the first time you hit the strip with the gaa you produce a good deal of side reactions as the gunk the strip is made of is dissolved by the acid this consumes some of the acid but also significantly retards the reaction and since its gaa and not aa the 1% water already present retards it further. Ive found that if you do the acid, heat until dry, add water to neutralize, acid again it works much better. Even when i use aa i find it makes a difference, i just can use much less aa to accomplish the same thing.

As for sources im some what piecing these together myself as i read more and more from all of the chemistry texts i can find that are about morphinan chemistry and substitutions. I'll try to include at least some in the next one i do understand that theyre nice to have. Most of them are ancient though and not really completely reliable. Also remember that ive been talking about doing some bupe analog threads for at least a few months, it takes awhile to get all the systems in place
Dr. Mario !gWLn19/oKs - Thu, 22 Jun 2017 21:01:45 EST ID:yMkR3gDV No.580584 Ignore Report Quick Reply
Hey Q, if i have the 8.6mg zubsolv tablets with menthol in them.

If i were to make only ONE converted version of bupe, to only be snorted/plugged, which would you pick? The safer the better.
JVenom !b1B269E8M. - Thu, 22 Jun 2017 22:14:41 EST ID:Pw2MG3k5 No.580585 Ignore Report Quick Reply
So by GAA I'm assuming you mean Glacial Acetic Acid right?

Just wanna be 1000% sure before I waste any material on trying this out.
Q !57aon8jsJ2 - Fri, 23 Jun 2017 01:16:52 EST ID:ztWD2hgP No.580589 Ignore Report Quick Reply
99% Glacial Acetic Acid is what i used, I think GAA is sold as either 98% or 99% though and i cant say for sure if the 98% is good enough.

Currently this one. Although im very interested in replacing the sodium acetate with zinc acetate, which according to a number of texts i read from like around 1920 using zinc acetate with AA will guarantee that you make diacetyl-bupe-acetamide rather than just di-acetyl which i kind of assume sine theres a lot of messy side reactions this is making a bit of each. Im also looking into removing the cyclopropyl group from the amine as this should create a full agonist. I have a few other ideas that are a bit more involved that im not ready to get into but right now i like this one.
Phyllis Brookstone - Fri, 23 Jun 2017 01:27:00 EST ID:r4H2txOr No.580590 Ignore Report Quick Reply
Fuck, man! I've been wondering for the past couple of weeks if it was possible to make my suboxone a little less shitty. Thank you. You kept me busy while I wait for my check to roll in so I can go pick up. Screencap incoming.
Phyllis Brookstone - Fri, 23 Jun 2017 01:31:15 EST ID:r4H2txOr No.580592 Ignore Report Quick Reply
Hold on, pick up time. Soon, folks, soon.
Phyllis Brookstone - Fri, 23 Jun 2017 03:45:08 EST ID:r4H2txOr No.580596 Ignore Report Quick Reply
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Phyllis Brookstone - Fri, 23 Jun 2017 03:46:06 EST ID:r4H2txOr No.580597 Ignore Report Quick Reply
Phyllis Brookstone - Fri, 23 Jun 2017 03:46:46 EST ID:r4H2txOr No.580598 Ignore Report Quick Reply
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Fuck, sorry. High.
Phyllis Brookstone - Fri, 23 Jun 2017 03:47:50 EST ID:r4H2txOr No.580599 Ignore Report Quick Reply
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Phyllis Brookstone - Fri, 23 Jun 2017 03:49:21 EST ID:r4H2txOr No.580600 Ignore Report Quick Reply
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Phyllis Brookstone - Fri, 23 Jun 2017 03:50:10 EST ID:r4H2txOr No.580601 Ignore Report Quick Reply
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Phyllis Brookstone - Fri, 23 Jun 2017 03:54:54 EST ID:r4H2txOr No.580602 Ignore Report Quick Reply
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Phyllis Brookstone - Fri, 23 Jun 2017 03:57:20 EST ID:r4H2txOr No.580603 Ignore Report Quick Reply
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Phyllis Brookstone - Fri, 23 Jun 2017 04:04:29 EST ID:r4H2txOr No.580605 Ignore Report Quick Reply
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Phyllis Brookstone - Fri, 23 Jun 2017 04:05:47 EST ID:r4H2txOr No.580606 Ignore Report Quick Reply
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Phyllis Brookstone - Fri, 23 Jun 2017 04:06:41 EST ID:r4H2txOr No.580607 Ignore Report Quick Reply
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Phyllis Brookstone - Fri, 23 Jun 2017 04:09:15 EST ID:r4H2txOr No.580608 Ignore Report Quick Reply
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Last one. Sorry for bumping the fuck out of a month old thread but this needed a screencap, even if it is a shitty one.
Q !57aon8jsJ2 - Fri, 23 Jun 2017 05:41:55 EST ID:ztWD2hgP No.580612 Ignore Report Quick Reply
Im also looking into quite a few potential opi RCs based on highly non-traditional synthetic opis which are not covered in even remote ways under the CSA. I'll be talking with labs in china over the next month or so to determine which of the many im looking at would be possible to synth there, relatively cheap, fast to produce or with existing patents or any other texts describing the synth. Id like some feed back from everybody though so im about to make a thread on that tonight.

As a teaser my next bupe analog thread wont be for a couple months i suspect because im running low on quite a few materials, my 1 liter bottler of 99% GAA is down to about its last few hundred MLs, im out of AA, I need a vessel i can pressurize safely that wont be damaged by the reaction, i need a bit of very high quality nitrous oxide, and a few other items but ive got leads on all of the stuff just not the funds to buy it all at once. However the goal is to find an OTC route to producing 6-AZIDO-morphine, 8-azido-morphine or other azido substitutions for morphine buprenorphine and other opis, such as Morphazide (replacement of the methyl on the amine of morphine for an azide) as the azido group seems to have extremely favorable pharmacokinetics and should be safe for amateurs to conduct at home using all otc materials. this should also provide insight into producing 6-amino or 3-amino or a few other excellent looking chems. as does another unusual substitution, carboxamido specifically at positions 8, 6, and the amine. Im also trying to find a way to easily swap hopefully a hydroxy for either a nitro or sulfonyl substitution and quite a few very other substitutions i dont yet have a grasp on mentally in terms of how to proceed forward with at the moment. My next bupe analog will most like be something like buprenorphine-N-descyclopropyl-ethylazido hopefully functioning more similarly to an n-phenethyl replacement or another azido substitution somewhere else. Yah so I have A LOT of projects in the works.
MDCB !txtI0IGNgk!!VyqqkppB - Fri, 23 Jun 2017 08:53:34 EST ID:LLOkl3GY No.580618 Ignore Report Quick Reply
Thank you kind anon.
Baron Von Feelsgood - Fri, 23 Jun 2017 12:14:01 EST ID:wHAvn2tX No.580645 Ignore Report Quick Reply
Just a question, would this method (GAA rather than AA) work with morphine to (even partially) acetylate it?
Dr. Mario !gWLn19/oKs - Fri, 23 Jun 2017 12:16:34 EST ID:yMkR3gDV No.580646 Ignore Report Quick Reply
Which bupe analog is easiest to make and safest to consume non-IV?

You didnt directly answer my question.
Baron Von Feelsgood - Fri, 23 Jun 2017 12:25:46 EST ID:wHAvn2tX No.580647 Ignore Report Quick Reply
Also, just a heads up, but you might want to remove the EXIF from your photographs before you upload them. LEO definitely use sites like these and even if you don't have GPS info in your EXIF, the serial number for your phone will be in the EXIF file, or at least code unique to that phone only.
Q !57aon8jsJ2 - Fri, 23 Jun 2017 13:19:16 EST ID:ztWD2hgP No.580650 Ignore Report Quick Reply
Just slap it with AA if you want easiest. As i said before i find that even with aa it helps to run it twice. Thats def a goodun and is fast and easy to make.

Ive heard 99% GAA can be used to selectively make 6-mam, not really sure how much i trust that so take it with a grain of salt. Adding a dash of sodium acetate might be enough to push it over the edge to form 6-mam but again im not positive.

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