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Black Pepper by Wesley Tootway - Tue, 18 Jul 2017 18:44:33 EST ID:DvsH6PdY No.129807 Ignore Report Reply Quick Reply
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>piperine is a MAOI
>piperine is in black pepper
>swallow a decent handful of black pepper
It has a pretty heady but pleasant effect, enjoying it T+ 20
Any of you fancy attempting a high from the spice cabinet?
1 posts omitted. Click Reply to view.
Nigel Duckspear - Sat, 29 Jul 2017 17:02:22 EST ID:ZN11u+84 No.129843 Ignore Report Quick Reply
You need to mix it with tumeric if you want anything from it. The tumeric makes it 2000% more potent.
Charlotte Goblingmuck - Mon, 31 Jul 2017 18:05:04 EST ID:EmeUDnw3 No.129848 Ignore Report Quick Reply
Most herbal MAOIs are reversible, vs irreversible synthetic MAOIs like Nardil. Neither will get you high.
Jenny Gankinbodging - Thu, 03 Aug 2017 10:20:39 EST ID:Nl1UIE3Z No.129860 Ignore Report Quick Reply
I can attest to the glory of black pepper. The best way to consume it is to either take whole peppercorns and fry them up with a good hunanese recipe, or to sprinkle crushed peppercorns onto a meal. For more info, check out /nom/
Caroline Blomblefock - Thu, 03 Aug 2017 12:00:02 EST ID:lDiZwPCu No.129861 Ignore Report Quick Reply
Phoebe Bardson - Sun, 06 Aug 2017 02:15:17 EST ID:/gsxOQoo No.129872 Ignore Report Quick Reply
I think the only half-decent psychoactive in my spice cabinet is cocoa powder.

Pill ID? by Lillian Drebblewell - Sat, 05 Aug 2017 11:34:21 EST ID:NYp/6nqv No.129867 Ignore Report Reply Quick Reply
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I was given this pill and told it's a benzo of some sort, however I've never seen a pill that looks like this and can't find any similar online either. Anyone got any idea what it could be?
Lillian Drebblewell - Sat, 05 Aug 2017 11:35:25 EST ID:NYp/6nqv No.129868 Ignore Report Quick Reply
On the flip side's only a score, no other imprint than the 'E'.
Augustus Damblewater - Sat, 05 Aug 2017 17:08:39 EST ID:arKOKSou No.129869 Ignore Report Quick Reply

1,4-butanediol by Sophie Summerdale - Tue, 25 Jul 2017 20:51:37 EST ID:B1HArXd1 No.129830 Ignore Report Reply Quick Reply
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What kind of company do you need to buy 1,4 from sigma or any large chemical supplier?

I don't want to buy a lot, But I don't want to pay fucking 50 dollars for 30ml like the only site I can find it on that doesn't ask for credentials.

I am a security guard at a jewelry store and I get packages sent there, Do you think I could use that?

How much of a company facad do you need to order from the big sites like sigma?
Barnaby Gubberford - Tue, 25 Jul 2017 21:03:36 EST ID:S5eEZMy1 No.129831 Ignore Report Quick Reply
Esther Duckstone - Fri, 04 Aug 2017 08:08:54 EST ID:h4qCq79W No.129864 Ignore Report Quick Reply
Dick polishing liquid.

You're welcome.

lofepramine by Caroline Pammerstetch - Fri, 28 Jul 2017 21:25:23 EST ID:nsJgy8rr No.129839 Ignore Report Reply Quick Reply
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Dr has put me on lofepramine. I told him that I think I have PE - been on other drugs for anxiety that haven't helped.
has he bullshitted me cause I can't see any info on this being used to help this?
1 posts omitted. Click Reply to view.
Caroline Pammerstetch - Sat, 29 Jul 2017 05:41:21 EST ID:nsJgy8rr No.129842 Ignore Report Quick Reply
I guess.
I know that SSRI's are more commonly used and appear to have an affect whereas TCAs don't seem to be used for this. They affect seretonin, but to a lesser degree? I was wondering if anyone has any experience specifically with TCAs because googles not bringing anything up.
Abberon - Sat, 29 Jul 2017 21:41:02 EST ID:48fKs968 No.129844 Ignore Report Quick Reply
I remember reading this on the paroxetine wikipedia article a long time ago and I found again: "Several studies have suggested that paroxetine can be used in the treatment of premature ejaculation. In particular, intravaginal ejaculation latency time (IELT) was found to increase with 6–13-fold, which was somewhat longer than the delay achieved by the treatment with other SSRIs (fluvoxamine, fluoxetine, sertraline, and citalopram). However, paroxetine taken acutely ("on demand") 3–10 hours before coitus resulted only in a "clinically irrelevant and sexually unsatisfactory" 1.5-fold delay of ejaculation and was inferior to Clomipramine (Anafranil), which induced a fourfold delay." You can find it here: https://en.wikipedia.org/wiki/Paroxetine#Research

Clomipramine is a TCA and it apparently can make one take 4 times as long to ejaculate after just one dose.

>There are also other options for PE such as lidocaine spray you can buy in sexshops and I've heard good things about it. I think you can now also buy condoms with lidocaine in them.
>Dapoxetine is a short acting SSRI that was created specifically for PE and can be taken only when needed.
>Kanna is a natural SRI which might work but I don't know for sure, this last one is just a hypothesis.
Charlotte Goblingmuck - Mon, 31 Jul 2017 18:16:28 EST ID:EmeUDnw3 No.129849 Ignore Report Quick Reply
I didn't know what lofepramine was but googled it, it seems to mostly be a noradrenaline reuptake inhibitor. I take amitriptyline, it doesn't cause anywhere near as much libido/orgasm problems as SSRIs, likely due to it (and most tricyclics) selectively antagonising certain serotonin subtype receptors.
Priscilla Heblinghure - Mon, 31 Jul 2017 23:29:59 EST ID:RUx2xDlb No.129850 Ignore Report Quick Reply
Well adrenergic and muscarinic receptors are responsible for ejaculation and erection when it comes to the autonomic nervous system and serotonin and norepinephrine are involved in the central nervous system during ejaculation so I'd say it has a good chance of working.
Samuel Gossledug - Tue, 01 Aug 2017 02:37:21 EST ID:d253OyZI No.129851 Ignore Report Quick Reply
DXM can work, just sayin'

Adderall by Cat - Wed, 19 Jul 2017 05:36:01 EST ID:/deuP2/9 No.129809 Ignore Report Reply Quick Reply
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I am trying to find a doctor who will easily write me an adderall script. Does anyone know of any Dr./psychiatrist who easily writes scripts?
Cedric Hinkinfield - Wed, 19 Jul 2017 13:08:48 EST ID:RM3UnEpd No.129810 Ignore Report Quick Reply
Dr. Mumbo Jumbo
Polly Hummledene - Wed, 19 Jul 2017 23:38:21 EST ID:1mrnr9mU No.129813 Ignore Report Quick Reply
yer mums cooter easily writes scripts
Fuck Nunningfield - Thu, 20 Jul 2017 18:25:56 EST ID:kMcJoFBJ No.129818 Ignore Report Quick Reply
Of course Officer, right this way.

Wellbutrin (Bupropion) by Nathaniel Pittdale - Wed, 19 Jul 2017 22:52:15 EST ID:qyZd5aZi No.129812 Ignore Report Reply Quick Reply
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So any of you boys try taking Bupropion recreationally? I'm pretty fucking bored of being sober at the moment and I really don't want to fuck with Diphenhydramine anymore, and I don't know anybody to get some real shit anyways. Besides, I'm looking for another job so I need to be clean.

I've read some experiences on Erowid and people said it had a mild stimulant effect on them, I crushed up 300mg and insuffalated it a few weeks ago but didn't really notice anything myself. I bitched out and didn't take the whole thing since it burned like a bitch though.

Just curious if anybody else has done this. Also if anybody can recommend some decent legal ways to get a buzz that'd be really appreciated. Going to a headshop this weekend to get a cracker and some N2O so I don't have to do jolly african-american shit like this again
Henry Cuzzlebirk - Thu, 20 Jul 2017 12:23:32 EST ID:RUx2xDlb No.129814 Ignore Report Quick Reply
Nah, you can't get high off wellbutrin. Might want to look into nootropics, I hear some can be recreational at higher doses. Phenylpiracetam is supposed to be kind of speedy and tianeptine is supposed to be like an opiate at higher doses. There's always Kratom and poppy seed tea too.
Fuck Nunningfield - Thu, 20 Jul 2017 18:15:17 EST ID:kMcJoFBJ No.129817 Ignore Report Quick Reply
Though phenylpiracetam certainly boasts the capacity to be stimulating, I would submit from my own experience with PhenP that it lacks in any recreational value, unless you like to recreate by learning!

In combination with stimulants with "recreational value," it seems to prolong the duration of said stims, whilst doing what it does and boosting linguistic ability among other higher functions. It also serves as a potent remedy for memory impairment, confusion and scatterbrain resulting from stimulant intoxication, sleep deprivation, ADHD, and acute cannabis consumption, to name what I can identify IME.

Also, Wellbutrin is marketed as a drug of abuse in prisons where most available drugs are pharmaceuticals, and pharms with abuse potential are, I would imagine, controlled and dispensed even tighter than on the outside. I cannot recall the documentary I heard this information from.
Nathaniel Dillershit - Fri, 21 Jul 2017 09:47:03 EST ID:d253OyZI No.129820 Ignore Report Quick Reply
I'm being pedantic here, but tianeptine is an opioid at appropriate doses. It's a full agonist at the mu opioid receptor.

Nootropics by justlookinforadvice - Fri, 03 Feb 2017 17:09:33 EST ID:DaLp8+rP No.128923 Ignore Report Reply Quick Reply
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I have been experimenting with modafinil for about two months now and let me just say that I definitely am a little more confident, focused, and driven to succeed. I have also tried microdosing lsd, which is great in its own right, but its better suited for those who have jobs where creativity or social interaction is needed, rather than a straight drive to get the job done. Would anyone like to share about their own experiences with such substances? I hear phenibut and piracetam are worth taking a look at but I would like to see what you guys' personal experiences have been
38 posts and 8 images omitted. Click Reply to view.
Ebenezer Snodham - Wed, 12 Jul 2017 18:11:31 EST ID:kMcJoFBJ No.129782 Ignore Report Quick Reply
... Did you have a choline source?
Ebenezer Snodham - Wed, 12 Jul 2017 19:23:51 EST ID:kMcJoFBJ No.129784 Ignore Report Quick Reply
Nootropics are tricky, as each nootropic is liable to have differing pharmacokinetics and/or pharmacodynamics, meaning each substance has to be taken with respect to its own optimum dose range and dosing regimens, taking into account the interactions between each respective nootropic in a stack in addition to how you yourself respond to the substance.

You take 300mg of Phenylpiracetam with 300mg to boost 4-5hrs later (with a choline source, I prefer pre-loaded but I've never found this to be necessary) and you will very likely experience some notable nootropic effect in time for that daunting test with the essay question you know is just waiting to inscribe the meaning of pain into your dominant palm.

In contrast, if you took 300mg Piracetam and boosted after 6 hours with another 300, it's doubtful you'll experience much nootropic effect in time for the exam. Not only does Piracetam tend to require doses of 1-2g+ (in total throughout the day, split into 2-3 doses) before starting to shine, it also doesn't really start to shine until you've been keeping up your regimen consistently for weeks (IME, and in the experience of many others).

My experience is mostly with racetams, I wouldn't consider the likes of L-Tyrosine or other amino acid/neurotransmitter precursors to be any more nootropic than a large serving of meat & alternatives. They're nutrients. They only become nootropic once you're on actual nootropics that partially diminish or exhaust stores of neurotransmitters.

IME racetams shine in stacks, and I've found no partner more comp[limentary to nootropic effect than the original "smart drug," amphetamine. IIRC, they compliment one another quite amicably both pharmacologically, on paper, and cognitively, in practice. The only concern I could muster (aside from not yet-well-studied-but-nonetheless-seemingly-negligible-if-present-whatsoever long-term side effects (in excess of 30 years, 1 week for some of these new racetams) was a potential for glutamate excitotoxicity and resultant apoptosis, dopamine excitotoxicity " ", and a very weak link to what I imagine might cause a lowering of the seizure threshold as a result of AMPA/kainate receptor modulation, but I didn't get far into that reading before my ADHD took me on a detour.

Speaking of which: for fuck's sake, I got distracted for three seconds just now and stumbled upon this:
Don't let the "nature" tag fool you, this is a real medical journal. Apparently, amphetamine coaxing more dopamine out of those neurons might mitigate some of the glutamatergic impacts on its own.

Regardless of the neurotransmitter causing excitotoxicity, the actual process of cell death is closely linked to the production of reactive oxygen and nitrogen species in the uh... Cytoplasm? Insubstantial. What matters is that these chemicals are powerful oxidizers that contribute to the complex chain of events leading to the destruction of nerve terminals. This process can be interrupted, slowed, and it's damage reduced (if not prevented entirely) by generous loads of antioxidants. Here's the catch: generous loads. Ketamine or dextromethorphan can protect against glutamatergic excitotoxicity IIRC, but my readings suggest that my favourite drug here-to-shake-up-the-pharmaceutical-industry, cannabis (namely THC, CBD, and no doubt the hundreds of other cannabinoids found within its buds) contains antioxidant properties that are substantial, if my interpretation of the literature is accurate. In a nutshell, constantly keeping cannabinoid levels up in your bloodstream can contribute to a multi-faceted antioxidant and anti-inflammatory defense that I'd bet my neurons on.
Comment too long. Click here to view the full text.
Ebenezer Snodham - Wed, 12 Jul 2017 19:37:12 EST ID:kMcJoFBJ No.129785 Ignore Report Quick Reply
I will go out on a limb here and make one prediction, however. I think that the general consensus concerning daily doses of phenylpiracetam is true in that one should expect diminishing returns, but I could swear I still reap benefits well into the following day. Perhaps a dosing schedule of 3-4 days per week, leaving at least one day in between each dose, could provide sustained nootropic benefit.

I dunno... I can't help but feel that PhenPir's effects push on beyond the chemical's elimination... Don't ask me how.
Henry Cuzzlebirk - Thu, 20 Jul 2017 12:52:41 EST ID:RUx2xDlb No.129815 Ignore Report Quick Reply
If you're worried about excitotoxicity you should try adding memantine to your stack. It'll keep your brain from frying and also helps reduce tolerance to stims.
Fuck Nunningfield - Thu, 20 Jul 2017 18:03:50 EST ID:kMcJoFBJ No.129816 Ignore Report Quick Reply
So I've heard. I'm weary of a dissociative throttling brainpower... Then again, I'm thinking more of dextromethorphan.

If only I had the funds...

Opiate withdrawal day 3 by Nathaniel Billingbanks - Sat, 15 Jul 2017 00:43:21 EST ID:lo77mcXi No.129793 Ignore Report Reply Quick Reply
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Took 500mg GABA, 3750mg of Kratom, two squeezes of
Skullcap extract in water to alleviate symptoms. Haven't eaten all day.
Jenny Clinderstone - Sat, 15 Jul 2017 11:46:08 EST ID:1dmnO1mh No.129794 Ignore Report Quick Reply
Good stuff! Is "GABA" the same as Gabpentin/Neurontin? I've heard Lyrica (Pregbalin) is much more effective because Gabapentin has a ceiling effect.

I'm using Lyrica for mild heroin wds, with great success. I was strung out for years but only using occasionally now. If I binge for a few days, I get sick, even though I haven't used daily in 4 years (including one year taper on methadone). If you can get your hands on Lyrica, I highly recommend it for wd symptoms (just be aware it adversely affects motor and cognitive function at high doses).
Rebecca Drarryput - Sun, 16 Jul 2017 20:51:50 EST ID:p6W1vm/U No.129798 Ignore Report Quick Reply
No, GABA is GABA, the neurotransmitter of which gabapentin is an analogue (IIRC, phenibut definitely is). GABA barely crosses the BBB unless you take like 5g of it. Even then its pretty useless for most people, except possibly for increasing growth hormone levels.
OP, if GABA is ineffective, and it probably is (also extremely short lived), I'd suggest phenibut or maybe picamillon though I've never used it myself. Phenibut has the advantage of not making you hugely itchy like high dose GABA
Cedric Hinkinfield - Wed, 19 Jul 2017 13:21:12 EST ID:RM3UnEpd No.129811 Ignore Report Quick Reply
I think there's a way to convert GABA into picamillion through heating it. Not 100% sure but if you google it there should be a tek to convert it where it'll pass the BBB.

For myself, I'm on gabapentin ~2600mg and ~3g of kratom. Feeling pretty lit! Had a job interview, which is why I took the gabapentin. Think I aced it tbh, but I might have looked like a deluded monkey to the sober people interviewing me haha.

Oxygen Bars by Priscilla Gerringgold - Tue, 18 Jul 2017 14:47:00 EST ID:Y7EJa7Z8 No.129804 Ignore Report Reply Quick Reply
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>work for this stoner lady who runs a few restaurants in my town
>she partnered up with some other lady and started a salon, including an oxygen bar
>10bux for ten minutes (and by ten I mean they forget how long you been on that shit and don't care much either

So here's the thing. Oxygen, in a concentrated application, is considered a perscription based on FDA rules, although FDA doesn't give two fucks because it's fucking air, who cares. I tried it myself, the aromatherapy is pretty nice, but other than that does inhaling a shit fuckload of pure oxygen do anything?

I mean it's just super air, right?
Sidney Shakeworth - Tue, 18 Jul 2017 15:27:49 EST ID:RM3UnEpd No.129806 Ignore Report Quick Reply
Think it helps athletes. You can run/swim/cardio MUCH longer after inhaling pure oxygen, since your blood vessels or whatever pump shit better. Not a scientist. But yeah I'd totally hit it up then go to the gym and get fat fuckin gains. Probably beats any pre-workout for actual effectiveness.

Will this get me high? by Yuuuuu - Mon, 12 Jun 2017 15:49:46 EST ID:UX6JmVEJ No.129668 Ignore Report Reply Quick Reply
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Boutta be spraying some of this shit into a balloon and inhaling/rebreathing. What to expect? (Don't tell me I'll die unless I'll ACTUALLY die)
Fuck Blozzlepure - Tue, 13 Jun 2017 16:03:40 EST ID:xFz49Vvu No.129671 Ignore Report Quick Reply
you took a picture of the label instead of the ingredients
have fun
Cedric Dungerbanks - Tue, 13 Jun 2017 17:00:32 EST ID:FT2JNH0D No.129672 Ignore Report Quick Reply
Contains difluoroethane and tetrafluoroethane
Jack Bavingdock - Sat, 17 Jun 2017 22:51:42 EST ID:d253OyZI No.129685 Ignore Report Quick Reply
There actually is a real risk of sudden cardiac arrest.

Getting high on nothing by Music anon - Wed, 07 Jun 2017 08:56:09 EST ID:QsCj48aR No.129625 Ignore Report Reply Quick Reply
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I'm here to discuss my medical and mental condition that brought me here, to talk about a very peculiar situation: i can get high on nothing.
More specifically, i can get high on music, as it's always my favourite catalyst, and when i am not listening to music i try to remember it to trigger this event.
Please forgive if my language is confusing, i'm not a native speaker, and i have problems clinging to words atm.
Story in the thread.
15 posts and 6 images omitted. Click Reply to view.
Priscilla Wannerdale - Mon, 19 Jun 2017 16:49:03 EST ID:z2Ml4oT+ No.129697 Ignore Report Quick Reply
You seem like a spiritual person, don't wanna insult you with my opinion but it might make some sense and put you in the right direction for research

You've already said you experience psychosis.
That mixed with synaesthesia might be what you have (synesthesia for possibly more results as that's US spelling)

I don't have psychosis, but I got synaesthesia. The most common form is "seeing" colours responding to words, or music, or associating one sense with another (e.g. the name of a town is "blue" in colour, or will bring up a specific smell)
Some will actually see it, akin to a hallucination but more as an "overlay" to normal vision, some will experience it in "their mind's eye" - like a visual memory.

Mine's kinda weird, I have shapes, objects, texture (and when high on almost anything colour is an aspect). Mine is very tactile. Dissonant tones will warp and push my head, leave a bad taste in my mouth, a specific song's base note might make me imagine a hairless tennis ball, the density and feel of it as the song progresses.

Anyone who's taken high doses of acid might have experienced something similar, though at (probably) a more intense scale. I imagine synaesthesia would just become more pronounced with psychosis, as it does with almost any altered state.
the flicker !FwnV7hV52I - Thu, 22 Jun 2017 05:02:45 EST ID:+6ypgndt No.129704 Ignore Report Quick Reply
Ruzbihan writes of his first awakening:
"[At the age of 3] we had a mosque at the gate of my house. I saw some children and asked them, 'Do you know your God?' They said, 'It it said he has no hands or feet.' For they had heard from their parents that God Most High transcends limbs and members. But when I asked that, I was filled with joy and ran, and something happened to me similar to what happens with the lights of recollection and the visitations of meditation, but I did not know the reality of what happened."
Music anon - Thu, 29 Jun 2017 01:15:45 EST ID:QsCj48aR No.129717 Ignore Report Quick Reply
I am very positive that's not the case.
I can't empathize at all with what you just described, and more than that the few hallucinations that actually mattered (the one creating the whole issue, and the one freeing me from that psychological trap i had created) were both completely silent.
Music barely helps "awaken my feelings" if it makes sense, cause all i see is emotion based.
Ebenezer Snodham - Wed, 12 Jul 2017 18:28:37 EST ID:kMcJoFBJ No.129783 Ignore Report Quick Reply
Goosebumps are about the only response to music that I experience that is reminiscent of drugs (aside from seemingly every other aspect of listening to music, come to think of it).

Sometimes I'll experience a warm, soothing rushing sensation travel through my scalp and down my spine, sometimes isolated to the left or right hemisphere. It feels a little like an orgasm mixed with a sudden application of a topical ointment that simulates a warm burning feeling. This is sometimes accompanied by a feeling not dissimilar to goosebumps, but lacking raised hair follicles.

Thing is, it's triggered by a number of things, not all of them external stimuli. Sometimes my own thoughts will trigger this brief sensation, sometimes it will be music, a strong emotion, a concept, or (rarely) touch. I have no idea how to pin it down and I don't experience any perceptible change in consciousness.

Weird shit mane
Wesley Settingsare - Thu, 13 Jul 2017 20:45:46 EST ID:nPIoD9EG No.129787 Ignore Report Quick Reply
Time to look up ASMR!

Question by Charles Sillerbone - Tue, 04 Jul 2017 01:36:30 EST ID:mn+WTfhv No.129736 Ignore Report Reply Quick Reply
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Can I get high off these? My dealer said they are hydro but I'm not sure
3 posts omitted. Click Reply to view.
Abberon - Wed, 05 Jul 2017 13:34:49 EST ID:qsqotcrA No.129747 Ignore Report Quick Reply
If it's true you got seriously screwed. You didn't even get some of the better, harder to get nsaid like pyroxicam or celecoxib, you only got the lame naproxen otc crap.
I hope you're only trolling.
Bombastus Werrywag - Thu, 06 Jul 2017 04:12:33 EST ID:cMdYVa/V No.129748 Ignore Report Quick Reply
Calm down. He asked this thread 40 minutes after the one on /opi/. Dude probably feels bad enough already.

OP. Take em for a headache or give em to your friends or something.
Jack Fiddleworth - Thu, 06 Jul 2017 05:13:01 EST ID:d253OyZI No.129749 Ignore Report Quick Reply
Yeah, I was raging pretty hard last night I'm afraid.

It was posted 10 minutes after the other thread was replied to though, I realise they may not have seen the replies by then though. Basically yes, I can be an arsehole when I'm wearing my angry pants.
PS, are you the real bombastus or not?
Bombastus !uYErosQbLM!!Mybq1UbK - Fri, 07 Jul 2017 11:02:37 EST ID:2NeU0hAr No.129751 Ignore Report Quick Reply
Ye. After half a decade on this site, SWIM has only now appreciated the auto-gen'd namefield on this site.

>inb4 secure trip codes are for faggots
William Deshtad - Wed, 12 Jul 2017 13:51:45 EST ID:N9nM/GYy No.129781 Ignore Report Quick Reply
yup, you're a faggot. at least you're aware though.

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