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BWD by Simon Blurringhood - Tue, 15 Nov 2016 23:30:46 EST ID:5/Nca8Mf No.349104 Banned Ignore Report Reply Quick Reply
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You know what to do. Grip n Sip.

User was banned for this post
User was banned by: owenfart for 01 minutes
295 posts and 125 images omitted. Click Reply to view.
Oliver Fettingstone - Mon, 16 Jan 2017 22:10:25 EST ID:yWo6jw9k No.351058 Ignore Report Quick Reply
You sound like you are mad jelly, all because you don't have a good job,
Blowing all your money on drugs, and living your life as a snob.
Can't get yourself a woman, or even a man for that matter,
So, you take life's frustration out on others, and imagine ending yours with a splatter.
Probably got some nasty virus, from some stupid old gross dirty slut,
All because you have poor judgement, and just jumped right into that cunt.
Some worn out trash, hooked on drugs, who now thinks they are above everyone else.
So now, let me say this to you mother fucker, get lost and go kill yourself. NB.

How was that? It’s little rough, but at least it’s something original and off the top of my head, unlike your ripped off cringy bullshit.
Beatrice Sedgedock - Fri, 20 Jan 2017 13:16:12 EST ID:sUT28RDU No.351198 Ignore Report Quick Reply
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Archie Gonningstone - Fri, 20 Jan 2017 20:28:13 EST ID:FtwkO1bD No.351216 Ignore Report Quick Reply
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Ebenezer Haffinglone - Fri, 20 Jan 2017 23:47:10 EST ID:8glX45Dx No.351226 Ignore Report Quick Reply
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$bump i need dosh 4 da sizzurp$
Barnaby Sangershaw - Sat, 21 Jan 2017 02:58:14 EST ID:Y8Ew2/KU No.351229 Ignore Report Quick Reply
I have been out of the RC game for a while now, but I got some DCK incoming and would like to know how potent it is as compared to MXE or 3-meo-pcp.

Any help would be of use.

Daily 3-meo-pcp use by Betsy Tootworth - Tue, 10 Jan 2017 00:16:28 EST ID:udH9Rs/b No.350825 Ignore Report Reply Quick Reply
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I was just wondering if I could get some advice from people that have been taking 3-meo-pcp everyday for awhile, as I have been taking 15mg twice daily and have been loving the effects, and want to know if there can be any negative side effects that I should look out for. If not, I think I found my drug of choice and I am going to live a wonderful life by taking it everyday. I used to be a daily user of DXM and I just kind of want to know what I'm getting myself into by taking this every day.
44 posts and 9 images omitted. Click Reply to view.
Augustus Grimwell - Thu, 19 Jan 2017 00:06:58 EST ID:gOZCJGCR No.351138 Ignore Report Quick Reply
I'm sure we'll talk more. It's cool having those little moments yeah?
James Cimmleville - Thu, 19 Jan 2017 16:53:25 EST ID:NErY6CAk No.351174 Ignore Report Quick Reply
yeah :)
Fuck Pickford - Fri, 20 Jan 2017 18:49:16 EST ID:EjhiNbMu No.351206 Ignore Report Quick Reply
just saying this helps if your searching...
Fuck Pickford - Fri, 20 Jan 2017 18:51:10 EST ID:EjhiNbMu No.351207 Ignore Report Quick Reply

c'est moi. btw
Barnaby Sangershaw - Sat, 21 Jan 2017 00:10:41 EST ID:Y8Ew2/KU No.351228 Ignore Report Quick Reply
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Burdddd my nigga

Yeah the good old lab story mxe with the green stripe up top..

Was some good times, with jimbo and them.

And it was probably around 2014 if I remember correctly.

Glad to see your still around

Rolling rolling gone! by Cornelius Micklechire - Sat, 28 May 2016 17:50:59 EST ID:wRKv6D54 No.343080 Ignore Report Reply Quick Reply
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Roll an odd
Quickly drop 3-meow-pcp
Roll an even
Get up and leave man
Do not pick up cough syrup
Do not reroll for 30 minutes!

Roll a 0 and you must hit a 3rd plateau/ hole

Roll at your own peril
451 posts and 145 images omitted. Click Reply to view.
Priscilla Fupperman - Fri, 20 Jan 2017 14:20:45 EST ID:B5TxVgyj No.351200 Ignore Report Quick Reply
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James Fuckingwater - Fri, 20 Jan 2017 19:05:56 EST ID:EjhiNbMu No.351209 Ignore Report Quick Reply
so I never smoke weed, but I called up my guy because my girl has seemed a bit depressed and I just wanted to get her gram.

When I show up he gives me a gram and a half tells me not to pay for it and to give her a hug o.October

Plus I ended up getting an extra $1,000 on my car I did not know I was getting from the insurance today, then the appraiser decided to be an a****** and cancelled my rental today.

so some how I'm supposed to meet him on Monday which is 18 miles away without a rental car to get my check in order to buy a new car...

So yeah good and bad s*** today

thus rolling for meowww
Hugh Derrywell - Fri, 20 Jan 2017 19:31:56 EST ID:GW08yi4X No.351211 Ignore Report Quick Reply

Barnaby Sangershaw - Fri, 20 Jan 2017 20:47:24 EST ID:Y8Ew2/KU No.351217 Ignore Report Quick Reply
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Barnaby Sangershaw - Sat, 21 Jan 2017 00:01:28 EST ID:Y8Ew2/KU No.351227 Ignore Report Quick Reply
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Am I Fucked? by Ian Blagglechut - Fri, 20 Jan 2017 17:20:24 EST ID:Z1ax0NAR No.351201 Ignore Report Reply Quick Reply
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GUYS, fate has knocked on my door

On that day that our savior, Donald J Trump, has been inaugurated; I had also been blessed with an arrival of a sparkling package of 3-MEO-PCE

I decided to go my usual route, loading it into my meth pipe, sucking the sweet /dis/ vapors out of the melting powder. I got I diss'd and I haven't been diss'd in a while

But then! I go to my scheduled doctors appointment, we discuss the medications im on. I'm on Ativan.

Then she proceeds to tell me that there is a new law that I have to be screened for any drugs to make sure im not a liability on the Ativan!

OH SHIT! I just smoked 3-MEO-PCE..........

Am i fucked guys, am I fucked?
8 posts and 1 images omitted. Click Reply to view.
Betsy Brodgefoot - Fri, 20 Jan 2017 21:37:41 EST ID:mGSbWKTq No.351221 Ignore Report Quick Reply
also op dont worry even if it did get recorded (which it wont because you dont do drugs never have and this test will not be positive) there isnt some shared database of "medical records". only the same practices/hospital systems will have the records on you from previous visits. why do you think they ask you tons of questions about your medical past when you go to a new doctor?

no employer/anyone would ever see it.
Isabella Dillyshaw - Fri, 20 Jan 2017 22:38:22 EST ID:Z1ax0NAR No.351223 Ignore Report Quick Reply

Yeah just deny! Fucking doctors man I just googled if DXM can test false positive and it can for pcp so, ill just say that that I may have used used too much nyquil one night.

And yeah benzos and /dis/ can be very bad and socially destructive. I really should stop using benzos


The only thing is is that I think that there is a shared database idk?? but I'm less worried about jobs because they will just do the drug test themselves.
Phoebe Chebberlock - Fri, 20 Jan 2017 22:42:36 EST ID:DbgUvmmJ No.351224 Ignore Report Quick Reply
It also tests positive for opiates and two other things which I forget the names of because I'd never heard of them.
Most commonly it gives a false positive for opiates and PCP.
Isabella Dillyshaw - Fri, 20 Jan 2017 22:43:17 EST ID:Z1ax0NAR No.351225 Ignore Report Quick Reply
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BTW this 3-MEO-PCE is really good vaped which means its even better sublingual so

Samuel Crullydudge - Sat, 21 Jan 2017 03:21:25 EST ID:NErY6CAk No.351230 Ignore Report Quick Reply
this board isn't about politics, keep on topic, it's in the rules.

DCK Oral Dosing by Phoebe Gollyhall - Thu, 19 Jan 2017 21:26:02 EST ID:N9VJVBnT No.351183 Ignore Report Reply Quick Reply
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So I love shoving powder up my nose as much as the next person, but the duration can be kinda problematic depending on the setting. Like sometimes it's just not polite (to some people-- and the law) and/or convenient to be whipping out a baggie and key every 30-90 minutes.

Anyway, I was wondering for people who have experience with oral dosing if you could give a rough timeline?
> Time of onset
> Time of peak
> Peak duration
> Come-down time

It'd be nice to have a steady base-layer of dissociation going and I can always do a bump if I want to go a lil further. It'd be especially great if I could line it up with a whole /psy/ peak without redosing.
3 posts omitted. Click Reply to view.
Rebecca Sibberfield - Fri, 20 Jan 2017 09:51:41 EST ID:B6533SGF No.351197 Ignore Report Quick Reply
I don't really like it either but I think my tolerance is just fucked. It almost doesn't even make me dissociated, I just feel weird and dysphoric. I've had a couple good experiences with it before but eh. I remember ~15mg was perfect a couple times but now even 30mg just makes me feel shitty. Might need to experiment with 3meopce some more and maybe that's better.

DCK gets me that good buzzing dissociation but I have to take a shitload.
Phoebe Gollyhall - Fri, 20 Jan 2017 13:17:16 EST ID:N9VJVBnT No.351199 Ignore Report Quick Reply
Yeah I'm at about the same point with the DCK tolerance. It used to be cute little mini-lines, or bumps off the end of a pen cap. Now it's like full on lines to rack up and blow.

That's part of the reason I want to look into oral dosing too. If the potency is affected as little as other people have said, oh yeah,
> Potency of oral vs. insufflated?
... If potency is affected as little as people have said, then extended duration of oral dosing might save me some material. And I guess in the long run my nasal passages. DCK doesn't hurt like 3-MeO-PCP, but it sure as hell aint as smooth as K or MXE going up there.
Sophie Gucklewater - Fri, 20 Jan 2017 19:59:47 EST ID:pH8Nre+7 No.351213 Ignore Report Quick Reply
It works best plugged in my experience, but I hate waiting for oral dissociatives to kick in. It also can have a really nice rush when dosed that way.

Oral I don't have much experience with but I've tried it a few times. It takes about 45 minutes to an hour to kick in depending on stomach content.

Doses are about the same as snorted and higher than plugged, but the difference isn't as huge as with MXE or Ketamine.
Sophie Gucklewater - Fri, 20 Jan 2017 20:23:44 EST ID:pH8Nre+7 No.351215 Ignore Report Quick Reply

As someone who loves both drugs, I wouldn't mix 3-MEO-PCP and Deschloroketamine. Oh my fuck that's a horrifying combination. Pretty much every time I do it I become convinced I've ingested a shitload of heavy metals for some reason which usually ends in a panic attack. I get side effects which I never get with either drug on their own. I've blacked out every single time too.
Lillian Snoddock - Fri, 20 Jan 2017 22:31:29 EST ID:N9VJVBnT No.351222 Ignore Report Quick Reply
> I hate waiting for oral dissociatives to kick in.
I was figuring, do medium bump then swallow the main dose.
> It takes about 45 minutes to an hour to kick in
That's not bad. What's the peak duration?

Talking to your doctor by Albert Bliddlehood - Mon, 16 Jan 2017 12:06:10 EST ID:vyyNgoyg No.351038 Ignore Report Reply Quick Reply
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So im 19 and next week im going to see my first big boy doctor as in not a pediatrician that i saw until 18. Should i tell the guy about my extensive DXM and DPH abuse in the past? Or will it just make him withhold painkillers and shit if i ever need them
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Augustus Grimwell - Thu, 19 Jan 2017 01:19:43 EST ID:gOZCJGCR No.351150 Ignore Report Quick Reply
>Some 'doctors' even go so far as to believe that HPPD and other long term problems are appropriate punishment for experimenting with proscribed drugs.


I see HPPD as a freebie and a view of the world that most people will never know exists.
James Cimmleville - Thu, 19 Jan 2017 16:52:22 EST ID:NErY6CAk No.351173 Ignore Report Quick Reply
> I've had slight scoliosis and back pain
oh that's a completely different story, that's what chiropractors are there for and i'm with you 100%
it seemed like that person was suggesting a chiropractor over an md as a blanket statement, which is very very no
Fuck Pickford - Fri, 20 Jan 2017 18:47:41 EST ID:EjhiNbMu No.351204 Ignore Report Quick Reply
Never mention illicit or proscribed drug use to any doctor unless you are in a life-threatening situation where it is immediately relevant to saving your ass.
Fuck Pickford - Fri, 20 Jan 2017 18:48:16 EST ID:EjhiNbMu No.351205 Ignore Report Quick Reply
If you don't want to be red flagged that is
Samuel Crullydudge - Sat, 21 Jan 2017 03:23:55 EST ID:NErY6CAk No.351231 Ignore Report Quick Reply
there are times where it makes sense and is helpful and you're risking it, but yeah generally speaking do not do it

K-holes ruined by Ernest Gockleworth - Thu, 19 Jan 2017 09:15:17 EST ID:zPOa5G0G No.351166 Ignore Report Reply Quick Reply
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My k-hole experiences used to be colorful and visual and l'd be immobilised for the duration but these days l'm fully mobile and l black out another common theme for me recently is lots of screaming at the top of my lungs, much to the alarm of my neighbors. What gives?!
Charles Blythebanks - Thu, 19 Jan 2017 17:18:15 EST ID:pH8Nre+7 No.351176 Ignore Report Quick Reply
It might not be Ketamine, or it's cut with some other active compound. A lot of Ketamine is cut with or just straight up Deschloroketamine (aka 2-OXO-PCM, DCK, or O-PCM), which is more potent, less visual and more manic, so if you're doing Ketamine doses trying to hole it's not surprising you're blacking out if that's the case. I'd say it's 1.5x to 2x as potent as Ketamine in my experience. Similar potency to MXE but a little less potent. The mania and stimulation would explain the screaming.

Do you snort it? If so does it sting more than usual? DCK burns a good bit whereas Ketamine is smooth. Also if you get huge, off-white to tan-ish to pink crystals it's most likely straight DCK. Though it would probably be crushed up to be less obviously not K.
Rebecca Gollyway - Fri, 20 Jan 2017 04:55:39 EST ID:zPOa5G0G No.351196 Ignore Report Quick Reply
I figured its because l was overshooting the hole. I would do say 6 50mg bumps spaced about 20 minutes apart then get impatient and do 150-200mg which is overkill leading to bkackout territory.
Last night however l wasnt particularly aiming to hole, l was watching frozen planet (the nature documentary) and did 8 50mg bumps spaced about half an hour apart and my mind was blown! Alternate realities, lucidity, entity contact.
Man l'm thinking about all the ket l've wasted over the years lmao

24 cartridges of n20 safety by Nicholas Fellerdock - Sun, 15 Jan 2017 22:51:11 EST ID:tbfuGQaE No.351017 Ignore Report Reply Quick Reply
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I bought a 24 pack and I'm wondering if I'd suffer any serious consequences if I did them all in a day, I only intend to do 6-12 along with some ket because I've heard stories about that being amazing, like a DMT/Salvia style rip into a vivid k-hole even on a common dose of ket but having had nitrous in the past (never with any other drug) we all know how that goes. In the past I've been at festivals where $5-$10 a balloon was the limiting factor but I've never had such a large amount.

I have a very safe technique where I take deep breaths for about 10 seconds, empty my lungs, inhale for a second, breath for a second through the side of my mouth, inhale for a second and so on until I fill my lungs, then hold my breath for about 30 seconds

Gonna do a b12 regiment a week before and after
Eugene Gommerbanks - Sun, 15 Jan 2017 23:44:06 EST ID:1tpnrEB8 No.351020 Ignore Report Quick Reply
Bruh just go ham on the wippits I've done hundreds at a time and was cool
Molly Tillinggold - Mon, 16 Jan 2017 05:51:42 EST ID:0IgpcuCh No.351035 Ignore Report Quick Reply
24 whippets is nothing. You'll be fine. Come back with a trip report, bro.
Walter Trotman - Tue, 17 Jan 2017 08:18:17 EST ID:Wf414xHT No.351070 Ignore Report Quick Reply

Typed out a post about the b-12 depletion and then read your entire post.

You're good homie, the b-12 thing is really the only issue, apart from not depriving your brain of oxygen obviously.
Nigel Womblefuck - Tue, 17 Jan 2017 12:20:06 EST ID:vthHb1fH No.351074 Ignore Report Quick Reply
Ok I figured it out. The carts came today and it's really tempting so I decided I'll do half of them TONIGHT and then half of them on the weekend when I get the ketamine, perfect plan because I only have enough weed for tonight and nitrous by itself doesn't really do it for me
Charlotte Gizzleson - Fri, 20 Jan 2017 04:33:31 EST ID:E947SAee No.351195 Ignore Report Quick Reply
the k and nitrous combo fucked me up hard, and not in a good way. N2o is only good with psys ime though.

dxm + weed by Martin Bundlemag - Fri, 13 Jan 2017 15:12:04 EST ID:yIoNjjhr No.350909 Ignore Report Reply Quick Reply
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How does DXM feel different when you smoke?

I've never smoked while dis'd and want to know what I'm in for.
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Hugh Clibbergold - Sat, 14 Jan 2017 11:05:44 EST ID:1tpnrEB8 No.350946 Ignore Report Quick Reply
Duuude the herb plus dxm is a must for me now.
I'm a ex-heavy user and would do 16mg/kg minimum to 26mg/kg max per week and I got so accustomed to smoking whilst exploring the cosmos that now even when on a low play it feels a little empty if I don't toke

Be careful though I remember many a year ago when I first started smoking and/or taking pills on dex how intense it was like holy SHIT one time I smoked half a j of green crack and was convinced it was laced with meth, smoked it next day and it was fine, long story short I made my cuz come over cuz I thought I was gonna die for real lol I envy u I miss those old days and I have no good k hook :(
Caroline Blatherson - Sat, 14 Jan 2017 16:30:24 EST ID:vyyNgoyg No.350956 Ignore Report Quick Reply
Anyone ever mix ccc with tussin? Took 16 ccc and wondering if i should drop a 4oz as well
Sidney Neckleson - Tue, 17 Jan 2017 22:45:20 EST ID:buI0ikE1 No.351089 Ignore Report Quick Reply
With my tolerance this is pretty much my preferred way to trip or if not tussin, delsym (preferably actuallly). It's a fine combination, because one box I think is the safety limit for ccc's, so if you want more Dxm you need to get it from a pure dxm product. I also toss in 100mg DPH
Cornelius Himbledale - Thu, 19 Jan 2017 15:02:19 EST ID:yFlPg0/I No.351170 Ignore Report Quick Reply
The only bad experience I've had on weed or DXM happened when I smoked weed after I thought the trip was mostly over. I got way too fucking high and suddenly was full on tripping again. I became delusion ally paranoid, got up and walked around on automatic and was convinced my friends had been replaced with importers who were trying to kill me so I couldn't move into a new apartment the next week.
We still have a good laugh about that day from time to time.

I've always handled the weed mid-trip well because I know I'm supposed to be tripping but it does give me some spooked up paranoia from time to time.
Edward Fanderway - Fri, 20 Jan 2017 03:40:46 EST ID:51A5ElOn No.351194 Ignore Report Quick Reply
Way more potent, psychedelic, and colorful/hallucinogenic. Much more sedating and less manic.

Fuck by Betsy Ganninghot - Sun, 01 Jan 2017 15:56:43 EST ID:+CTLloXo No.350492 Ignore Report Reply Quick Reply
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>Buy a dozen bottles of DXM on the internet
>Get them a week later
>Decide to dose 600mg cause why not, I already have a shit ton
>No tolerance and I'm a lightweight
>Start tripping and listening to radiohead
>Wind up getting sucked into a vortex of blankets
>Stuck in a thought loop of opening and closing my door
>Have a seizure in the corner of my room
>Family calls an ambulance
>Yelling fuck at the paramedics
>Strapped down to stretcher in ambulance, think I've entered a different reality
>Go to ER
>Get a tube stuck up my dick
>Got some Ativan
>Hour long conversation with a psych nurse
Comment too long. Click here to view the full text.
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Nell Femmledale - Tue, 10 Jan 2017 17:28:25 EST ID:y23zgVYa No.350835 Ignore Report Quick Reply

Care to expand? I have had a few tonic clonic seizures in my time and they don't feel like anything, you completely blackout and have no memory of it.
Ernest Sandleshaw - Wed, 18 Jan 2017 22:00:15 EST ID:WJZH3ar3 No.351128 Ignore Report Quick Reply
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10/10 top kek
Augustus Grimwell - Wed, 18 Jan 2017 22:38:21 EST ID:gOZCJGCR No.351132 Ignore Report Quick Reply
Ive felt similar things from 3 meo pcp.

I'd say that's a proprioceptive hallucination. Not a seizure. You may have been shaking like having a seizure, but i'd bet if they ran tests it would show that you hadn't had one.
Esther Gullyford - Fri, 20 Jan 2017 03:23:47 EST ID:25jb2wti No.351192 Ignore Report Quick Reply
My first genuinely high 3rd plat somewhere around 13-14mg/kg, was chilling in my bed listening to music flying through spinning color vortexes one moment and blacked out throwing myself into the wall from muscle spasms hard enough to wake my sitter up on the couch downstairs. Very lucky not to have 911 called, managed to sit upright against the weight of a trillion anvils and gesture/hoarsely request a glass of water to avert the situation. Was numb as all fuck, though.

I've gone far higher many times since then, swear by a low dose of daily benzos that rounds out the dissos removing the toasty sensation/general dizziness/disorientation entirely, nothing even resembling a seizure ever happens no matter how stupid I've decided to be in the past. Then again, 2 days in a row/single heavy/reckless doses/combos have always been the height of my stupidity so I can't speak for the bingers so much.

Diclazepam is so fucking dirt cheap and mentally unintruding at the right dose (and with a little tolerance maybe) that I couldn't imagine not having it in a /dis/-user's arsenal. Between that and dots of sublingual noopept here and there over these past couple years it's like all the useless, lazy dopey brain cells have washed out/fried off and now my brain is exclusively a mix of jaded old /dis/-riding hotshots that like snorting fat lines of 4-AcO-DMT to scare some love of life into the sparky new recruits.
Edward Fanderway - Fri, 20 Jan 2017 03:36:11 EST ID:51A5ElOn No.351193 Ignore Report Quick Reply
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Im a lightweight too and taking 500mg blew me into another world and gave me a mini seizure.

3rd plateau DXM is an ENTIRELY different drug than 2nd plateau. Stick to 300mg.

3-MeO-PCP vs PCP by Cornelius Himbledale - Thu, 19 Jan 2017 17:47:15 EST ID:yFlPg0/I No.351177 Ignore Report Reply Quick Reply
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Has anyone ever actually tried both to know how different they are? No one ever talks about PCP here, I assume because it is not very commonly available due to the stigma around it. I assume they are honestly almost identical but I have done neither one so I don't know. Any insight?
Edward Clemmerlodge - Thu, 19 Jan 2017 19:01:54 EST ID:pH8Nre+7 No.351180 Ignore Report Quick Reply
I don't think it's exactly like PCP. I've never done PCP so I could be wrong but either way just because it shares most of the structure of PCP doesn't mean it's likely to be the same, even if it does have similar potency. 4-MEO-PCP is absolutely nothing like 3-MEO-PCP after all. It's over 10x less potent, the effects are more like DXM and Ketamine had some kind of fucked up love child and the binding profile is radically different than both PCP and 3-MEO-PCP. All from just moving the methoxy group one position over on the same ring. If I hadn't known it was 4-MEO-PCP I would have never believed it was even remotely related besides being a dissociative.

I'd love to read more comparisons by people who have tried both, though. PCP seems interesting, though 3-MEO-PCP seems better in every way.
Phyllis Dammerfield - Fri, 20 Jan 2017 00:50:20 EST ID:NErY6CAk No.351190 Ignore Report Quick Reply
3meo and oldschool pcp are very different, but they're more similar to eachother than they are to a k or mxe or dck
i have done it once, the dissociation is stronger and much more consistent throughout the duration, there's also more of a stimulating nervous tension imo

it's just like, really really fucking hard to come by genuine PC with any reasonable quality these days
Albert Tootway - Fri, 20 Jan 2017 02:24:10 EST ID:9jBGOfky No.351191 Ignore Report Quick Reply

Ya, PCP is king. With the rise in popularity of RC dissociative's you'd think it would start flooding the market again but it's still mostly a very niche drug and is only popular in certain hoods. Propaganda is a powerful thing. Most drug addicts of all kinds turn their nose up at it, because "shit, don't be like those crazy people on cops". It is like the nuclear bomb of dissociative's though, primarily because of the unknown dosages being smoked.

NMDA could ameliorate autism? by Hannah Pollerlock - Wed, 04 Jan 2017 06:40:05 EST ID:UvATaVTo No.350650 Ignore Report Reply Quick Reply
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Deficits in social approach behavior, rough-and-tumble play, and speech abnormalities are core features of autism that can be modeled in laboratory rats. Human twin studies show that autism has a strong genetic component, and a recent review has identified 99 genes that are dysregulated in human autism. Bioinformatic analysis of these 99 genes identified the NMDA receptor complex as a significant interaction hub based on protein-protein interactions. The NMDA receptor glycine site partial agonist d-cycloserine has been shown to treat the core symptom of social withdrawal in autistic children. Here, we show that rats selectively bred for low rates of play-induced pro-social ultrasonic vocalizations (USVs) can be used to model certain core symptoms of autism. Low-line animals engage in less social contact time with conspecifics, show lower rates of play induced pro-social USVs, and show an increased proportion of non-frequency modulated (i.e. monotonous) ultrasonic vocalizations, compared to non-selectively bred random-line animals. Gene expression patterns in the low-line animals show significant enrichment in autism-associated genes and the NMDA receptor family was identified as a significant hub. Treatment of low-line animals with the NMDAR glycine site partial agonist GLYX-13 rescued the deficits in play-induced pro-social 50-kHz and reduced monotonous USVs. Thus, the NMDA receptor has been shown to play a functional role in autism, and GLYX-13 shows promise for the treatment of autism. We dedicate this paper to Ole Ivar Lovaas (May 8, 1927–August 2, 2010), a pioneer in the field of autism.

>Yall niggers think Auts like me could get use out of theraputic use of dis for social shit and what have you.

>Unrelated I think, but I also have PTSD and it seems to not exist with diss use. Perhaps also a helping hand here?

FYI: Am much fucked outa my mind, very can not post right.
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George Fanville - Thu, 19 Jan 2017 01:00:40 EST ID:HWklJCo5 No.351145 Ignore Report Quick Reply
Have you ever recovered and got your wit back?
Augustus Grimwell - Thu, 19 Jan 2017 01:06:31 EST ID:gOZCJGCR No.351147 Ignore Report Quick Reply
Weed typically makes me feel retarded.

DXM use over has made me more social in the long run,but during binges and the height of my use i was a fucking hermit aside from my ritualistic trip buddy.

When you are living in the dextroverse idk how you could maintain any social life.

I definitely believe i gained a better perspective on some things and less of a fuck given in anxiety terms socially from all my DIS use. If any pros came from regularly fucking my brain with syrup for years then that would be it.
Augustus Grimwell - Thu, 19 Jan 2017 01:16:40 EST ID:gOZCJGCR No.351149 Ignore Report Quick Reply
I was antisocial to some degree most of my middle/highschool life. I had friends. Usually only ~5 i would hang out with, but when it came to anyone new or that did not come thru someone i knew i always had issues. I honestly feel i had some sort of persecutory delusion. Anything anyone said or snickered about in class made me think it was about me, and obvious attempts of chicks coming on to me i took as some sort of cruel mockery??

Looking back on it is bizarre. DXM truly broke that persecutory construct. Idk if it did so as a side effect of breaking other shit, or just giving me a look outside the box.

Either way i wouldn't have even spoke to my fiance if it weren't for DIS.
Martha Brimmerfoot - Thu, 19 Jan 2017 21:40:30 EST ID:OcRh0oMq No.351185 Ignore Report Quick Reply
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can attest to ptsd alleviation. schizophrenia as well..
Cedric Lightfield - Thu, 19 Jan 2017 22:54:19 EST ID:JI6z02Ak No.351189 Ignore Report Quick Reply
I can agree here that high doses seem to steer you the other way while low doses tend to land you closer to where you would like to be.

I can get behind this as well, I would not have had enough balls to ask the chick out I am now dating if I hadn't turned up to work with lovely levels of DXM in me.

Yeah I tend to notice psychotic symptom reduction along with the PTSD but I was wondering if perhaps it was the PTSD being alleviated that led to lesser symptoms of psychosis or schizophrenia.

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