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420chan is Getting Overhauled - Changelog/Bug Report/Request Thread (Updated April 10)
Dissons as a DOC? Ignore Report Reply
Beatrice Shittingshit - Thu, 29 Nov 2018 18:56:50 EST ID:k+RkqokZ No.364636
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Anybody feel this way? 3 ho pcp and ketamine (mostly 3ho) have been helping me not be an extremely depressed a lot with little side effects so far, and theyve been helping me ween of benzos a lot easier than anything else ive tried. We can all agree that benzo addiction is worse than everything but maaaaybe opiates. Any info on longterm semi regular use of this stuff? I gotta say I need to get off benzos and 3ho seems like a great candidate. And yeah yeah trading drug use for drug use but it feels safer to me than doing 40mg etiz a night
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Ian Poshham - Thu, 29 Nov 2018 19:46:29 EST ID:NP3RKcPT No.364639 Ignore Report Reply
>>364636
Doing ketamine on the.daily is pretty awful for your brain but the effects seem mostly reversible. It seems likely other dissociative a have similar effects. Here's one study, there are more around but I'm lazy. Do your own homework, Beatrice.
https://www.sciencedirect.com/science/article/abs/pii/S0306460313000269
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Charlotte Bessleville - Fri, 30 Nov 2018 02:37:58 EST ID:ZdLkBvi6 No.364641 Ignore Report Reply
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>>364639
Can't your bladder essentially crystallize if you take enough ket?

>Matt developed K bladder after taking as much as 15g of the drug a day.

K bladder is when the lining of the bladder gets so damaged and scarred that it shrinks in volume, which causes the person to need the toilet more.

Sometimes they can't go, leaving them in excruciating pain.
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Charles Dillywater - Fri, 30 Nov 2018 06:08:58 EST ID:76gXaXcy No.364642 Ignore Report Reply
>>364636
Ketamine and DXM have got me off opiates. the only down side i find is the irregular sleep patterns.
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Matilda Sebbleson - Fri, 30 Nov 2018 16:15:29 EST ID:6sAkZYbz No.364651 Ignore Report Reply
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>>364636
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3713393/ - Daily, long-term ketamine abuse can give you brain lesions.

DCK and K helped me get off benzos too, but I wasn't using them regularly, just when I would cut my dose. The glutamate rebound can come back to bite you in the ass.

>>364641
The amount of damage varies person to person, and some people never seem to get it while others get it bad. Ketamine depression treatment and ketamine abuse in Asia is bringing more funding to research on it.

https://www.sciencedirect.com/science/article/pii/S1879522615004236 - Antioxidants and reducing bladder damage

https://www.sciencedirect.com/science/article/pii/S1879522615004157 - EGCg, a green tea catechin, reduced bladder damage when co-administered with K in a rat.

https://www.ncbi.nlm.nih.gov/pubmed/29995815 - Hyaluronic acid instilled in the bladder reversed damage

https://www.sciencedirect.com/science/article/pii/S1879522615004066 - More hyaluronic acid research

https://pubs.rsc.org/en/content/articlelanding/2018/nj/c8nj03107j#!divAbstract - Thought this was interesting too, apparently these scientists are proposing DCK as an alternative to ketamine for long-term depression treatment because it's more potent, longer lasting, and seems to do about the same amount of damage (from their in vitro testing) as ketamine. You should be able to download the article to see the full paper.


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