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Harm Reduction Notes for the COVID-19 Pandemic

Beer and Grapefruit Juice

- Sat, 21 Sep 2019 17:09:37 EST ayQ9BFcB No.282748
File: 1569100177123.jpg -(72478B / 70.78KB, 520x520) Thumbnail displayed, click image for full size. Beer and Grapefruit Juice
It is like a brass monkey but better tasting and adds the needed bitterness that you would usually get from hops that is missing in malt liquor.

Grapefruit juice is also an inhibitor of cytochrome p450. This is the enzyme that is responsible for metabolizing many drugs, including ethanol.

Consuming a cytochrome p450 inhibitor results in higher blood plasma concentrations of ethanol. This is why you often see on the back of medications to not take with grapefruit juice.

You are welcome.
Phoebe Ceblingleg - Sat, 21 Sep 2019 18:15:19 EST /q2dOuY0 No.282750 Reply
I just posted this in /b/, but might as well post here, too. There's several types of cytochrome p450. Alcohol is metabolized by CYP2E1. Grapefruit inhibits several cytochrome p450 enzymes, but CYP2E1 is not one of them.

It is a great mixer, though.
Nell Dradgetet - Sun, 22 Sep 2019 12:33:21 EST ayQ9BFcB No.282753 Reply
Okay, fair enough. I suggest popping a Tagamet while drinking, as well as using a grapefruit mixer for taste.
Jarvis Bimbleville - Sun, 22 Sep 2019 16:26:57 EST 4H/9l7bZ No.282754 Reply
i had a few sips off a friend's grapefruit hefeweizen the other day. it was a low alc percent like only 3% but it was tasty
Ebenezer Sanningbury - Sun, 22 Sep 2019 21:56:26 EST zSF2cUPE No.282759 Reply
Schöfferhofer makes a nice grapefruit shandy, and I’ve heard Leinenkugel also makes a decent one. I’d rather have a sour than a shandy—more variety, more alcohol—but they’re great to sip the day away on your patio or doing yard work. Still, the ~3% ABV largely doesn’t do it for me, and the sweetness becomes cloying after awhile
Molly Fibberstone - Thu, 26 Sep 2019 16:33:04 EST jkPXrDJn No.282788 Reply
When I used to get royally smashed I would buy 5 or 6 grapefruits, a couple of lemons or limes, squeeze them, pour the juice in empty bottle, add a bit of organic honey and fill the other half (or the desired amount) with Moskovskaya or Russian Standard. Shit's was so fucking delicious and the morning after I would wake up feeling fine
Betsy Blazzlefuck - Thu, 26 Sep 2019 21:04:50 EST zSF2cUPE No.282791 Reply
This honestly sounds pretty, pretty good lol. Honey must offset the tartness of the lemons and limes, and I love grapefruit juice. May have to give it a try!
Barnaby Sarrydock - Sat, 28 Sep 2019 04:46:40 EST I2aDLRWk No.282795 Reply
yeah but really don't ruin it by using bottom shelf rubbing alcohol. I know it's idiotic to spend more than 15$ for a bottle of vodka but so is buying the cheapest stuff, unless you are broke as shit obviously... but in that case you should just chase it with iced water or any other standard fruit juices from concentrate
Rebecca Chobberway - Thu, 10 Oct 2019 17:32:49 EST PaDP+LlP No.282881 Reply
1570743169420.jpg -(158535B / 154.82KB, 1024x582) Thumbnail displayed, click image for full size.

Stolichnaya though. Gonna have to try this some time
Betsy Crurringbanks - Sat, 12 Oct 2019 00:44:42 EST 3JzoWIHj No.282892 Reply
hell yeah stoli is bottom shelf price for top shelf quality

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