/mdma/ Ecstasy Discussion
My GF is schizophrenic and wants to try MDMA. She's on risperidone and quetiapine.How safe is it for her to try MDMA guys? She's never done drugs before because of her diagnosis and wants to live a little.What could go wrong?How likely is it to go wrong?
>What could go wrong?the full scale unraveling of her grip on reality, possibly some bad reaction with the medications that fuck up her brain chemistryFor what its worth I have schizophrenia, I did a lot of MDMA and psychedelics in the year before it fully presented and collapsed into psychotic paranoia, I havn't done MDMA since but it took me years to be able to smoke even weed without it instantly flipping a switch of manic delusions, I still can't comfortably take psysI'd say start small if she's never done drugs before jumping right into something that powerful, and do serious research or consult a doctor to make sure the cocktail with her meds isn't gonna cause serotonin syndrome or something
>What could go wrong?
>>226382she won't feel anything as quetiapine is so fucked it's basically blocks all receptors
e makes me feel crazy as shit
Pretty sure she'll be fine. Antipsychotics don't affect serotonin receptors so there is no risk of her getting serotonin syndrome. She might roll a little less hard than normal but other than that nothing will happen.
>>226391Quetiapine has the following pharmacological actions:Dopamine D1, D2, D3, D4, and D5 receptor antagonist>Serotonin 5-HT1A receptor partial agonist, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7 receptor antagonist, and 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F receptor ligand
>Serotonin 5-HT1A receptor partial agonist, 5-HT2A, 5-HT2B, 5-HT2C, 5-HT3, 5-HT6, and 5-HT7 receptor antagonist, and 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F receptor ligand
Risperidone and quetiapine will both block a lot of the pleasurable effects of MDMA or methamphetamine. It's a waste of money.
Come on man. No, don't give you schizo gf MDMA.
>>226381It is usually advised that if you have any profound mental illnesses like / similar too what you're girlfriend has then as a general rule of thumb, NO. Psychoactive substances can have an unbelievably devastating on an individuals brain chemistry and perception of reality; even more so if she is on medications already to manage her condition. I can't stress how much of a bad idea this is.
>>226381From what I heard, MDMA could supress her symptoms but during the comedown (if there is any) they will intensify.
Get out get out get out get out get outGet >OUT
>>226381man if anything give her weed/
>>226497 false lol
Psychology is a weird fucking thing man.In 2011 when I was in high school I had a psychotic break and I thought people were constantly trying to poison/drug me. I smoked some weed once and it completely fucked my head. It led to extreme alcoholism just to deal with it. Now I'd like to say it's "cured" but I still struggle with it. I can smoke pot now and not lose my shit anymore which is nice. I dunno man, just make sure she is totally prepared to lose her mind if the trip goes bad.
If she's stable enough that she could be left alone detoxing from her meds without any serious concern for her safety or mental health then she could probably risk a half-dose without much problem. Still, if she is that stable better to just quit the meds and take the MDMA when they're out of her system and do a trial with M to see if it's a better medication.
Iono but when i was on risperidone i did coke all the time cutHigh in half tho
ive got schizophrenia and i took mdma today.id say it felt like i was slipping into my mind a bit too much and thinknig about stuff. but i didn't feel anything like i was going into psychosis... which i can feel because my mind races and i get weird tunnel vision and other thingsid say its probably not wise to. even weed isn't but I still smoke everyday too. mines isnt that bad in my last psychotic episodes was a few months back. psychosis just feels like it comes and go. I think i could take a high hit of psychedelics and still have my pills and feel fine. benzos cut my psychosis in that if im tyhinking paranoid, pissed off that ppl are poisoning me or something, i pop a xanax and calm down and i stop being paranoid. the antipsychotics kind of just dull you so you can't think
She gonna lose her FUCKING mind..
>>226381>schizophrenia>has to take two antipsychotics>taking a recreational drug that is known to induce mania >What could go wrong?Don't do it dumbass.
>schizophrenia>has to take two antipsychotics>taking a recreational drug that is known to induce mania >What could go wrong?
OP if you really care for the wellbeing of your girlfriend, discourage her from the drugs. Here's a suggestion, tell her that when she's recovered to a degree at which a psychoanalyst would discontinue treatment, she can try MDMA if she's been off all the meds for at least a year. Tell her it will be an amazing, therapeutic, life changing condition. I'm taking MDMA now after a long time of struggling with mental health issues (though nothing schizotypal or paranoid), and I'm glad I didn't take this before I was 99% able to deal with my issues sober. However, if she does absolutely INSIST on doing this (and you're worried for her safety if you're not there), maybe she can take a low dose orally (70-80mg is PLENTY, you can add more later but you can't get it out of your body once it's in there!). But OP you must absolutely be sober and in a good state of mind for that experience, as well as your girlfriend, no drugs that day or the days after (can't stress this enough). Having someone she love and trusts (you, presumably) as a sitter for a low dose roll is probably the safest way to do this if she's really dead set on gambling with her mental health. The best option OP is to take my first suggestion, wait until she is recovered and off the meds if she really must do this. No-one is saying any of this to ruin your fun or deny your girlfriend what could be a very useful therapeutic experince, but the truth is that we're all still unsure of the long-term (even short-term) effects of mdma use for people predisposed to psychotic disorders. Better safe than sorry, always. Best of luck to you and your girlfriend but please don't let her do something that might make the rest of her life plagued with cognitive abnormalities beyond those she's already familiar with.Please OP, try to talk her out of this until she's FULLY recovered. Sorry I realise I'm rambling and this might seem a bit overboard, but I've had friends totally fry their brains on this stuff who had no history of anxiety/depression. It's never worth the high OP, be safe and I hope you both have a long happy relationship (for the record I'm finding the therapeutic effects to be lasting, try to discourage using MDMA more than once every couple of months (can confirm if you don't do this your serotonin will be fucked and you'll be back to square one if you started as a manic depressive).
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