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Sandwich


Discord #Drugs Channel Now Open

Muh dick don't work!

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- Thu, 24 May 2018 23:07:05 EST o8KpmEdB No.55419
File: 1527217625802.jpg -(42095B / 41.11KB, 567x430) Thumbnail displayed, click image for full size. Muh dick don't work!
well, my thread subject might be a bit hyperbolic. I'm 22 and don't have 'actual' ED, I just suffer from nervous doubt and panic whenever I get close to getting laid, causing my little guy to be completely non cooperative. I also probably watch too much porn but I'm putting that behind me.
all things considered, I'm thinking of ordering some cialis online to help give me some peace of mind and 'get my mojo back' so to speak. I think if I can successfully have sex a few times my doubts will be cured. If anyone has experience using cialis I was wondering;

>dosage
There seems to be a dosage meant to be taken prior to sexual activity (10mg or 20mg) also a lower one called 'daily dosage' (2.5mg or 5mg). If anyone has experience with both methods, which one helps best to make you more virile, if at all?

>stamina
Does it help you last longer? not a huge deal but would be a nice perk.

>side effects
can girls tell if you're using it? Am I putting myself at major risk if I use it whilst very drunk, should I avoid mixing it with mdma period?

this is all pretty embarrassing shit to have to ask at my age but fuck it, would just like some advice. cheers
>>
Beatrice Horringstetch - Thu, 14 Jun 2018 15:15:32 EST puYODoEl No.55431 Reply
If it's nerves you'd be better off taking a dose of propranolol not cialis. Anything used for ED in a young male like you will end up giving you ED in twenty years. Take a beta blocker. It's what people use for performance anxieties like you have. Cialis and Viagra are for old men and cuties, you're not either and I wouldn't subject you to the long-term side effects of such.

black market biohacking

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- Tue, 22 May 2018 13:23:25 EST KmFr/pzj No.55417
File: 1527009805656.jpg -(23787B / 23.23KB, 495x362) Thumbnail displayed, click image for full size. black market biohacking
>want to inject adenoviral vectors into brain
>can't find underground docs
eeeeeeeeEEEEEEEE

When having sex, feeling of electric shock in hands

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- Sat, 19 May 2018 21:50:03 EST BnbbVvQn No.55416
File: 1526781003450.gif -(2064519B / 1.97MB, 540x540) Thumbnail displayed, click image for full size. When having sex, feeling of electric shock in hands
Sometimes when having sex and excited about it more than normally, I feel tremor (quiver) and some numbness in my both hands. The feeling affects whole hands (maybe except thumbs), but it is stronger in my little and ring fingers and correspondent part of palms. It isn't quite visible, but my partner can feel by touch that my hands actually quiver. Last time I also felt my fingers gripping together involuntarily. With an effort I could straighten my hands, but relaxed hands clench together like gripping a tennis ball. Overall feeling was similar to having shocked by electricity, rather mains kind of voltage. What could than be? Happens once a few months or even years.

Cocaine seizures and brain hemorrhages?

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- Sat, 19 May 2018 07:29:39 EST me32i+8e No.55415
File: 1526729379475.jpg -(118262B / 115.49KB, 1200x600) Thumbnail displayed, click image for full size. Cocaine seizures and brain hemorrhages?
I was hanging out with a couple friends who were doing blow and one of them ended up seizing for several hours after we went to bed. She probably did at least a gram or two but idk. Is it likely that her seizure was a result of a brain hemorrhage or permanent damage? Are these symptoms likely to return? This was several months ago and to my knowledge she hasnt had anymore seizures and still occasionally does blow

Nihilism?

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- Mon, 26 Mar 2018 21:48:20 EST 5gb4OGx4 No.55344
File: 1522115300045.jpg -(55192B / 53.90KB, 600x600) Thumbnail displayed, click image for full size. Nihilism?
This seems like a right place to mention this.

Hey everyone!

I got drunk and started to think about what I said to someone earlier which basically mean but not directly, "I believe there's a creator that created everything, but I refuse to believe on the meaning in life that may have been passed down through history through history or that there may be an objective meaning to life.

Am I trying to be edgy without fully realizing it at times?
>>
Samuel Drottingforth - Fri, 18 May 2018 01:32:45 EST aAtEqGEw No.55412 Reply
I believe in a lot of different things. My most major religious belief is in Krishna, who I also call God, Universe, Creator, Om, etc. I have a very eclectic knowledge on this sort of subject, and find hinduism to be the most advanced though I get truth from all religions.
Sorry for the tangent, but what I'm trying to say is you're right. There is literally no point to this existence, not just our existence but the existence of the whole of material energy.
We exist as souls, and have been living lives since time immemorial. Changing bodies as we change clothes. The souls is timeless, and God for example, lives outside of the material. We however, are under illusion. You know how an ant only lives like 3 weeks? Well it feels like a lifetime to it. Same with dogs, their lives length feels no different than ours because it's all perspective (youth, manhood, old age, death). Well the life of the universe is trillions of years according to the Vedas. They say when Krishna breath's outward, infinite universes are created, of which we are one. When he inhales they cease to exist forever. The entire existence of our universe is in one breath of God. We are trapped in the material illusion and cannot conceive what the spiritual world is like.

What is this?

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- Sun, 29 Apr 2018 12:55:00 EST HVokmtsk No.55387
File: 1525020900853.jpg -(1058095B / 1.01MB, 2576x1932) Thumbnail displayed, click image for full size. What is this?
I think it's a wart but I looked closer at it and I don't think the skin should be broken at the top but she has been picking at it. I'm asking because she made an appointment with a doctor but I'm hoping y'all could save us some monies.
>>
Jenny Fammlefeck - Sun, 29 Apr 2018 14:50:29 EST avX1suez No.55388 Reply
>>55387
Looks like a wart to me but I can't even tell what part of the body that is.
If that's a hand it looks like she could wrap up a basketball like a toddler could hold on to a M&M in their fist
>>
Rebecca Trotridge - Tue, 15 May 2018 00:04:55 EST /WUPR0no No.55410 Reply
>>55387
Get some salicylic acid wart remover and use that. Cut it out with a clean razor blade fairly deeply then cauterize it with a hot nail if that doesn’t work.

Bloody Gums

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- Wed, 25 Apr 2018 13:18:10 EST 6wsEfzyA No.55384
File: 1524676690902.jpg -(43613B / 42.59KB, 600x400) Thumbnail displayed, click image for full size. Bloody Gums
I just had cleaning on my teeth done and its so bad it made my gums bleed. Is it safe to drink coke now? Or should I wait a few days?
>>
Wesley Bunhood - Wed, 25 Apr 2018 22:05:06 EST r1Y31/eq No.55385 Reply
stop drinking soda faggot
>>
Eliza Honeybanks - Wed, 09 May 2018 23:39:19 EST DUhS+Jbr No.55409 Reply
>>55385
Start flossing my man, or better yet dish out $40 for a Waterpik and use it once every few days for perfect gum health.

Possible bi polar-I miss it !

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- Wed, 09 May 2018 21:59:31 EST VF9kR59U No.55407
File: 1525917571072.jpg -(31725B / 30.98KB, 192x269) Thumbnail displayed, click image for full size. Possible bi polar-I miss it !
Long story short because I could babble on for ever...

I'm going on 30 an do think I've had bi polar most of my life

I may not have extreme depression or mania but I do seem to get phases of not being assed to do anything my self,taking an easier part time job for less money and staying home alone doing nothing but maybe going the gym and the guy in my sub conscious telling me "just hurry up and end it"

Few months of this phase I always have a month phase of wanting to go around the bend..I'll finaly get out there and start partying,I'll do 2 day benders,I'll book holidays I'll have crazy ideas what could workout well I'll randomly inbox a load of girls I don't know trying to get dates and succeed a few times...aTen bang it will hit me again "fuck the world this is rather meaningless,what's the point we all die any way,I've done it all before,why was I born blah blah blah

I've never knew tho if I'm actualy depressed as in chemical imbalance,jjust unhappy with a boring life or the friends I'm with(mental awerness of how things could be) or maybe it's just happening around the winter times (well November to June for a brit like me)

I could be wrong about the dates or the diagnosis but what I do know is I defiantly have a strong flucation in moods.

I'm sure what I experience a few times a year for a few weeks at a time is mania.

I feel full of too much energy,I don't wanna sleep,I wanna talk shit and do shit I feel like I could conquer the world.I feel sort of like I've had coke but say half he strength and without the urge to do more coke or the actual euphoria,but I do feel good in my self.

what ever it is I'm seeming to feel the high part a lot less and I feel as if I've come into this sort of accepted depression.
What I mean by that is I'm not actualy sad I don't feel bad but I've took on once again a nighlistic sort of look at the world(I think) I think life's shit and pointless but I don't really cry at that fact or moan outload I just get on with it...

so my theory is I either have bi polar or it's just I physically need to do more with my life for it to be fulfilling

I think it's both because of the mania phase

>question
How do I enter a state of percent mania ?
Or beside telling the doctor how can I sort of fix this my self ? I'm going try and do psys again with good people when I can get them and try to make some nootropic stack up.

>btw
Family
Members have depression
Comment too long. Click here to view the full text.

New Skin medication, caused itchyness, scratched the fuck out of it

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- Wed, 09 May 2018 15:03:20 EST wYjB6lGe No.55405
File: 1525892600806.jpg -(3093445B / 2.95MB, 3024x4032) Thumbnail displayed, click image for full size. New Skin medication, caused itchyness, scratched the fuck out of it
Any suggestions for creams or something to heal up these scratch marks I gave myself? Im on a generic form of Accutane which is essentially last resort back/shoulder/chest/ acne treatment only used once all else fails. Dermatologist prescribed. After my first 2 days on the stuff the back of my head and my neck began to itch, and at first it was just one little spot, but then, it felt like after gently scatching to the one little pinpointed spot that I irritated the skin and it became one of those things where as I scratched it became more itchy. Ive showered and washed, and its not like there is spreading rash now but damn. I fucked my shit up scratching like a madman for a few minutes. Wat do?
>>
Ernest Pushford - Wed, 09 May 2018 15:08:47 EST wYjB6lGe No.55406 Reply
1525892927806.jpg -(211079B / 206.13KB, 745x1573) Thumbnail displayed, click image for full size.
>>55405
Also guys here’s a bit of info
> Myorisan (isotretinoin capsules) is a retinoid indicated for the treatment of severe recalcitrant nodular acne. Nodules are inflammatory lesions with a diameter of 5 mm or greater. The nodules may become suppurative or hemorrhagic. Because of significant adverse effects associated with its use, Myorisan should be reserved for patients with severe nodular acne who are unresponsive to conventional therapy, including systemic antibiotics. Myorisan is available in generic form. Common side effects of Myorisan include:

Just hammer the damn screws in

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- Tue, 08 May 2018 15:02:15 EST GfBkLqEp No.55401
File: 1525806135383.png -(81318B / 79.41KB, 199x237) Thumbnail displayed, click image for full size. Just hammer the damn screws in
Hiya friends! I have a weird medical issue that's come up lately, and figured I'd ask you folks about it, in case anyhone with any medical expertise at all comes here.

So I do intramuscular injections weekly, but for the past couple of months the solution keeps on leaking back out of the entry point! I haven't changed anything about my injection method from how I've been doing these injections for a couple of years now.

Now I do need this medicine, and it is kinda expensive too - it comes out to about $15/shot, so that's a hell of a waste.

So here's the idea. What would happen if I put a piece of Scotch tape right over the injection site right after pulling out the needle? It's nonporous and sticks to my skin pretty closely, so... maybe it could be used to "lock in" the fluid until it properly disperses through the muscle by blocking the exit route?

Or would that instead cause some sort of bizarre complication? Thoughts?

I use 21G 0.8mmx25mm needles if it matters - it's just what was prescribed to me.
1 posts omitted. Click View Thread to read.
>>
Doris Dobblehood - Wed, 09 May 2018 03:30:53 EST c8PxTNQj No.55403 Reply
Also forgot to mention that the glue on scotch tape gets melted by water, rendering it doubly ineffective. nb for double post.
>>
Lillian Pandlelare - Wed, 09 May 2018 12:50:55 EST GfBkLqEp No.55404 Reply
>>55402

I have been rotating injection sites, lol. The injection is just 1ml, I was taught to only do it in the thigh area but rotate legs weekly and choose new sites along the thigh each time.

I did gain a bit of weight lately (gained ~15-25% of my old bodyweight, thanks unemployment), figured that could have been the root cause but my doctor said it wasn't likely. I think they underestimated how much weight I gained, haha. I'm 100% willing to believe you, may have to look into getting some longer needles to drill through this blubber and/or try to figure out an injection method which gets through it better.

I'll give the gauze massage a try, thanks!


<3 u Internet Doctor
>>
Sophie Sicklesterk - Fri, 25 May 2018 23:58:58 EST X47PfYiP No.55422 Reply
Same boat bro. This is a very easy fix. Don't use tape.

You merely need to offset the injection puncture site. Doctor showed me, it's called the Z method or some shit.

Say you're injecting your left thigh and you're right handed. Place your left hand on the skin of your thigh and grip slightly, and pull/push the skin about an inch from where it normally sits. Keep holding it and inject with your right while the skin is offset. After you withdraw the needle, release the skin. the injection 'exit' won't line up and no fluid will leak.

Anime is bad for your health

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- Wed, 14 Mar 2018 12:22:05 EST uZ/+z0YU No.55326
File: 1521044525870.jpg -(69456B / 67.83KB, 610x343) Thumbnail displayed, click image for full size. Anime is bad for your health
It can turn a normal people into gay if they watch it often.
Take for example Larry and Andy Watchowski, they were a junky otaku fanboys, and in the end the illness made them into transgenders...
The same thing does the Korean dorama, don't watch them too often, or you will loose your mind.
5 posts omitted. Click View Thread to read.
>>
Caroline Dallerforth - Mon, 02 Apr 2018 12:16:12 EST Rl1gAmmt No.55353 Reply
>>55326
>be weeb
>be straight
sorry mate, your theory has been debunked. if it's any consolation, i exclusively date asian girls tho
>>
Fucking Clusslehall - Sun, 08 Apr 2018 03:00:01 EST 0avoadko No.55365 Reply
1523170801706.png -(35649B / 34.81KB, 870x798) Thumbnail displayed, click image for full size.
Ok, so shitposting is allowed on this board, good to know.
>>
Ian Pagglewadge - Tue, 08 May 2018 12:01:04 EST YolLnUsS No.55400 Reply
1525795264161.jpg -(50336B / 49.16KB, 1080x374) Thumbnail displayed, click image for full size.
DICKS EVERYWHERE

shitty hearts club band

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- Sat, 24 Mar 2018 17:14:12 EST UEp0JFVo No.55336
File: 1521926052184.jpg -(78764B / 76.92KB, 462x627) Thumbnail displayed, click image for full size. shitty hearts club band
I'm 23 and experienced what I think were mild symptoms of a heart attack yesterday, including chest pain, fatigue, high blood pressure, and complete lack of appetite despite having worked for 12 hours with no food or anything. I had been feeling real fatigued for a couple of weeks and couldn't figure out why... then blammo.
I probably drink too much coffee and have had an incredibly stressful 7 or 8 months.
I had a 2 or 3 month relationship with cocaine with I was like 18.
Quit smoking 4 months ago after ~8 years. I was doin like 2 packs at my worst.
I'm going to go to a doctor and get an EKG but I guess I just want to know if anyone has experienced anything similar and what was your experience with it? Am I young enough that I can just make lifestyle adjustments and not have to worry about it, at least not til much later?
Once again, I'm going to the doctor, but I just want to ease my mind and talk about it in the meantime...
thanks <3
2 posts omitted. Click View Thread to read.
>>
George Drummlehare - Tue, 27 Mar 2018 20:05:13 EST r1Y31/eq No.55346 Reply
what would you tell a child who went 12 hours without foods but "wasn't hungry?" youd tell that little fucker to shut the fuck up and eat his dinner, because you know he needs the nutrition. same goes for you. brain > instinct
>>
Caroline Dallerforth - Mon, 02 Apr 2018 12:25:06 EST Rl1gAmmt No.55354 Reply
>>55336
literally me at 20 years old. working 10~11 hour shifts, running on coffee instead of food, going through some particularly stressful months. had all those symptoms plus a brief moment where i lost vision - woops!

it sounds like you had a bad episode of anxiety - very unlikely it's a heart issue, the EKG should give you some peace of mind. like others have said here, you should definitely take better care of yourself. eat food, don't forget to drink a bit of water, and cut down on that caffeine homie.
>>
Molly Worthingforth - Wed, 02 May 2018 08:29:51 EST DUhS+Jbr No.55393 Reply
You've gotta learn that even if you're not hungry, you still need to eat like clockwork. Put gas in the tank, and your body will thank you for it. Of you really want to be good, start cooking bulk meals and bring one or two to work each day for you to heat up and smash real quick.

what do i do with my life

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- Wed, 10 Jan 2018 23:36:48 EST KawohyP7 No.55222
File: 1515645408914.png -(351563B / 343.32KB, 731x682) Thumbnail displayed, click image for full size. what do i do with my life
Should I try for optometry school and become optometrist or is this a bad idea?
or maybe go for medicine?

I don't care about money or prestige or any of that stuff and I have no shadowing experience so I am weighing both options equally right now. I feel like I like the romanticized aspect of medicine but if I'm being realistic with myself I'm interested in Optometry and prefer a slower lifestyle and I can have a life completely unrelated to work.

I'm a Computer Science undergrad who's two years into his degree and quickly realizing this probably isn't for me and that I'm the kind of person who will probably only feel satisfied in health care . Been a secret desire since childhood but always figured I was too dumb. I don't have much in the way of pre-requirements. I'm not sure what I'm doing with my life. I'm posting here to see if anyone else has advice or something in the field
16 posts and 2 images omitted. Click View Thread to read.
>>
Angus Finningshit - Sun, 25 Mar 2018 20:39:14 EST IuzjpJ/C No.55341 Reply
>>55328

Not OP, but thank you for writing this. I needed to read it.
>>
Caroline Dallerforth - Mon, 02 Apr 2018 12:46:12 EST Rl1gAmmt No.55355 Reply
>>55222
>prefer a slower lifestyle
>life completely unrelated to work

Stay far, far away from medical school.

That being said, you can work in health care and enjoy a great lifestyle division. Optometry is pretty cush if that's your thing - Fit lenses, give eye exams, fuck bitches. You may not be able to find that sweet lifestyle you want if you go into something like nursing, EMS/paramedic, or physician assistant. You sure as fuck do not want to be a physician if you want a lifestyle separate from work.

If your gut says health care, go for it homie. Do some research and find out what the job is really like though - A lot of people quickly realize the "romanticized" aspect of medicine or health care is very different from what the job is actually like. A good chunk of people get scared and hop back into their IT or business field lmao. If you're insane like me and realize you wouldn't be doing anything else, go for it :)
>>
George Snodville - Mon, 16 Apr 2018 23:49:53 EST +tG3mFif No.55376 Reply
>>55355
Why not go into the business of healthcare? Best of both worlds.

Psychotic thought that the schizo-gene shared is trial/error adaptation

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- Sun, 15 Apr 2018 03:20:09 EST dSA4F4Wp No.55373
File: 1523776809371.jpg -(42378B / 41.38KB, 540x304) Thumbnail displayed, click image for full size. Psychotic thought that the schizo-gene shared is trial/error adaptation
Any brain scientists, Psych doctors and DNA coders lurking humor this thought?


I'm schizophrenic in midst of psychosis, I've believed to have figured out from a binge watch on schizophrenia docs i've used as white noise, that i've mapped out the cause of schizophrenia

In the part of the brain where the input/output ratio is processed. out processors send out mixed signals causing us to chain into constant misunderstood {cause} = misfired {effect} (causing a blunt affect too)
I think the gene that causes that misfire of reactions to one's perception is the trial and error program written into our DNA meant to test adaptability by making it so that one's perception and cognitive reaction to be mixed matched from each other in order to promote adaptability to unplanned reactions. it's a survival tool gone....insane
>>
A_Wizard !cMZsY.BCnU!!vVWR8L52 - Mon, 16 Apr 2018 02:48:09 EST p98oIwAn No.55375 Reply
>>55373
That's a sound theory, though I can't test the DNA aspect myself. I'm too high and tired to really aid you directly at the moment, but I will suggest reading some classic texts that give good examples of thought analysis. http://www.sacred-texts.com/cla/plato/apology.htm
Also, by tracing your thoughts back to their origin, periodically throughout the day (especially when a thought seems weird), the practice will help you understand the methods involved in the thought processes as well as make you more consciously aware of them. This in turn will help get onto a path where you will learn to script your own thought processes and turn on and off various processes or throttle sensory input, as to allow better processing.
>>
Fucking Nummerstork - Tue, 17 Apr 2018 05:44:17 EST seInJVW2 No.55377 Reply
>where the input/output ratio is processed

Glutaminergic signalling

>In order to support the localization hypothesis, it would be necessary to show differing cellular signaling pathways are activated by NMDA receptors based on its location within the cell membrane.[39] Experiments have been designed to stimulate either synaptic or non-synaptic NMDA receptors exclusively. These types of experiments have shown that different pathways are being activated or regulated depending on the location of the signal origin.[44] Many of these pathways use the same protein signals, but are regulated oppositely by NMDARs depending on its location. For example, synaptic NMDA excitation caused a decrease in the intracellular concentration of p38 mitogen-activated protein kinase (p38MAPK). Extrasynaptic stimulation NMDARs regulated p38MAPK in the opposite fashion, causing an increase in intracellular concentration.[45][46] Experiments of this type have since been repeated with the results indicating these differences stretch across many pathways linked to cell survival and excitotoxicity.[39]

>out processors send out mixed signals causing us to chain into constant misunderstood {cause} = misfired {effect} (causing a blunt affect too)

Breakdown of the kynurenine pathway of tryptophan's metabolism.

>A recent study shows that a genetic variation resulting in decreased expression of SNX7 is linked to increased central levels of kynurenic acid and ultimately to psychosis and cognitive dysfunction in bipolar disorder

>We conducted a genome-wide association study (GWAS) against CSF levels of KYNA in BD that revealed a genome-wide significant association with the single-nucleotide polymorphism (SNP) rs10158645 within 1p21.3, a finding that was replicated in an independent cohort of BD patients.

>I think the gene that causes that misfire of reactions to one's perception is the trial and error program written into our DNA meant to test adaptability by making it so that one's perception and cognitive reaction to be mixed matched from each other in order to promote adaptability to unplanned reactions.

>Research is done on 10–12 genes on 1q21.1 that produce DUF1220-locations. DUF1220 is an unknown protein, which is active in the neurons of the brain near the neocortex. Based on research on apes and other mammals, it is assumed that DUF1220 is related to cognitive development (man: 212 locations; chimpanzee: 37 locations; monkey: 30 locations; mouse: 1 location). It appears that the DUF1220-locations on 1q21.1 are in areas that are related to the size and the development of the brain. The aspect of the size and development of the brain is related to enthusiasm (macrocephaly) and schizophrenia (microcephaly). It has been proposed that a deletion or duplication of a gene that produces DUF1220-areas might cause growth and development disorders in the brain [12]

>Results of this research demonstrate that DUF1220 copy number is linearly associated with increased cognitive function as measured by total IQ and mathematical aptitude scores, a finding identified in two independent populations.[13][19]. This association has important implications for understanding the interplay between cognitive function and enthusiasm phenotypes.[20] These findings also provide additional support for the involvement of DUF1220 in a genomic trade-off model involving the human brain: the same key genes that have been major contributors to the evolutionary expansion of the human brain and human cognitive capacity may also, in different combinations, underlie psychiatric disorders such as enthusiasm and schizophrenia. [14]

1p21 variations leading to underactive NMDAR activity triggering a build up of toxic tryptophan byproducts that permanently inhibit the NMDA receptors affixed to dopamine neurons which leads to hyperfiring of dopamine neurons and the positive syndrome of psychosis (also implicated in affective disorders). Chronic disinhibition of glutaminergic firing leads to negative syndrome. The brain attempts to correct for this by elevating levels of kynurenic acid as kynurenic acid is neuroprotective but it cannot correct for terminal endings that have already been damaged which is why intervention during the first episode of psychosis is so conductive to good functioning. The more one stays in the psychotic state the more damage is inflicted upon the NMDA and thus the more one enters further psychosis …
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