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Loperamide

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- Mon, 09 Mar 2020 08:23:18 EST VWFpn1lf No.614092
File: 1583756598974.jpg -(70449B / 68.80KB, 504x470) Thumbnail displayed, click image for full size. Loperamide
Brainlet here
How to get high off Loperamide without killing myself?
>>
Albert Billingford - Mon, 09 Mar 2020 10:06:15 EST gE8yyxax No.614093 Reply
>>614092
Just know the doses you have to take.make it really hard ti piss or shit at all for many hours or even a day or two
And you will probably have a realllly painful shit a few days after you dose since the dose for constipation is low and you need to meha dose in order to force enough through your bbb at once to actually feel it. Because lope goes in your bbb and normally is immediately ejected
Hence why its an opiod with no high, so to speak. Because it only affects the guts opiod receptors
But take shit loads and your system floods reoeatedly putting in more than your bbb can force out, which isnt healty but its what people have to do if their dumb enough to not just maintain or taper with lope

poppy seed tea

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- Sat, 07 Mar 2020 16:56:27 EST fZUt6EKm No.614046
File: 1583618187853.jpg -(92605B / 90.43KB, 1200x875) Thumbnail displayed, click image for full size. poppy seed tea
How exactly do you make poppy seed tea? (if you have the unwashed seeds)
8 posts omitted. Click View Thread to read.

Taking klonopins while at methadone clinic

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- Fri, 06 Mar 2020 15:59:37 EST h1CJHjkg No.614030
File: 1583528377383.png -(247060B / 241.27KB, 500x375) Thumbnail displayed, click image for full size. Taking klonopins while at methadone clinic
I just thought I'd share with you guys that kpins dont show up on drug screens at clinics

they testing they use either IA or GS-MS test are insensitive to it because the heat destroys 7-aminoclonazepam

So anyone wanna share stories on there 'miraculous" passing
4 posts and 1 images omitted. Click View Thread to read.
>>
Ebenezer Hucklenock - Sat, 07 Mar 2020 17:29:27 EST YULpFGGC No.614048 Reply
I was taking between 4-6mg daily and getting my script from my primary care Dr and I never popped positive on any drug test, swab or urine and I know they were gc/ms tested.

You are right tho clonazepams metabolite is unstable in biofluid and the immunoassay and gcms test use extreme heat to create a gas which how they can see the metabolites
>>
Ebenezer Hucklenock - Sat, 07 Mar 2020 17:31:39 EST YULpFGGC No.614049 Reply
>>614048
And heat destroys 7-aminoclanzepam.

Source: wikipedia
>>
Hannah Henningmore - Sun, 08 Mar 2020 12:35:19 EST 5UGRCXaZ No.614082 Reply
>>614030
> kpins dont show up on drug screens
neither does tianeptine

How do you not blow your brains out in the opi game?

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- Tue, 18 Feb 2020 01:27:43 EST W0ct5kxG No.613668
File: 1582007263144.jpg -(16622B / 16.23KB, 480x362) Thumbnail displayed, click image for full size. How do you not blow your brains out in the opi game?
I've already suffered a subarachnoid hemorrhage, and I still use, it's just kratom these days luckily, and I'll take that over full agonist WD any day, but shit, kratom WD still isn't the greatest, the sleeplessness man, that's the worst. Also not to mention the insane stigma against us.

How do you guys stay sane?
4 posts and 1 images omitted. Click View Thread to read.
>>
lol - Tue, 18 Feb 2020 09:35:09 EST IggaRoSW No.613674 Reply
>>613668
Just got sick of it all and got on maintenance granted I've been doing this for a long ass time, if opi addiction is enough to make you wanna shoot yourself then the things you naturally deal with in modern life are gonna kill you first. It sucks but there's a lot worse things out there, as far as the stigma learn that it's there because of scumbag and it's an unfortunate side effect of your choice to get high, buy the ticket take the ride as they say
>>
Barnaby Pickson - Tue, 18 Feb 2020 12:06:36 EST Mjy8E5PD No.613676 Reply
>>613672
I can't stand kratom. i'm a junkie and am always teetering in the overdose region with kratom.

Opiates vs Benzos (which is worse)

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- Wed, 26 Feb 2020 09:49:18 EST eHTflFIT No.613813
File: 1582728558594.jpg -(12312B / 12.02KB, 298x227) Thumbnail displayed, click image for full size. Opiates vs Benzos (which is worse)
Which addiction/withdrawal is worse comparing oxy orally and benzo? Also after long term use which of these two causes the least depletion of the natural endorphins / opiod receptor / gaba receptor etc. oxy is pretty hardcore i suppose it wrecks the natural endorphins a lot more than benzo?
7 posts omitted. Click View Thread to read.
>>
Reuben Nishfoot - Mon, 02 Mar 2020 15:06:30 EST SUNa8wVi No.613952 Reply
>>613939
Pretty much this. Once you've experienced seizures there's not much opi WD can throw at you. Plus if you buy enough k to last a week then opi WD can be downright fun
>>
Graham Pendlebury - Sat, 07 Mar 2020 05:24:07 EST gE8yyxax No.614042 Reply
>>613952
If you have a small dissociative toleramce

Which most of us dont
Because it takes fucking yearssss to go down and mxe happened

K is best for the worse parts of w.d, hell yeah. 1 to 2 hour relief from everything

But if you have any toleramce you realllllyyy quickly get resistant again
>>
Lillian Tillingworth - Sat, 07 Mar 2020 19:12:50 EST OHIHxMID No.614051 Reply
A heavy Opi addiction -> CT you will want to kill your self
A heavy benzo addiction -> CT will kill you

You can get through a lot of bad opi WDs alone but w/ benz you’ll have to taper and if you don’t have the stuff to you’ll probably end up hospitalized if not dead

Heroin

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- Sat, 29 Feb 2020 03:43:23 EST LH0BPfvC No.613909
File: 1582965803920.jpg -(74748B / 73.00KB, 700x931) Thumbnail displayed, click image for full size. Heroin
So i have come to get my hands on some heroin the last days and of course have tried it. I am underwhelmed to say the least. Its rather pure stuff and does not contain Fentanyls (by the time of duration being ~ 12 h). It gives a nice itch and a nod and an overall opiatey feel. However there is very little euphoria. To be honest i have had better euphoria from Trams. Also my tolerance is nonexistant, as i have used Kratom two or three times a half year ago and harder opiates longer than a year ago. Am i doing it wrong or is heroin just shit?
What is all the hassle about?
13 posts omitted. Click View Thread to read.
>>
Thomas Trotstock - Fri, 06 Mar 2020 07:59:23 EST OY8VGOLR No.614025 Reply
>>613909
Yeah heroin for me is all about the IV rush. The actual high is OK, Or combining it with a stimulant like cocaine or crack. Now that's where its at. , I find dihydrocodeine at high doses to be much nicer.

coronavirus from middle eastern heroin?

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- Thu, 05 Mar 2020 20:12:56 EST yB2lulph No.614014
File: 1583457176354.jpg -(60232B / 58.82KB, 512x392) Thumbnail displayed, click image for full size. coronavirus from middle eastern heroin?
since Iran is a major smuggling route for european #3 heroin is it possible that coronavirus could survive in heroin similar to the anthrax tainted heroin case a few years (I realise Anthrax is a million times hardier than any virus but still). how long would you have to wait after buying to be sure that no surviving virus on the dope? would cooking kill any virus?
>>
Archie Bluffingshit - Thu, 05 Mar 2020 22:01:26 EST YofsFlfv No.614015 Reply
>>614014
put it the freezer for a week or so, also you could try heating the solution before use. only advice ive got.
>>
Matilda Henningville - Thu, 05 Mar 2020 22:42:21 EST Mjy8E5PD No.614017 Reply
>>614014
My advice is to not even worry about it. Seriously. Chances are slim to none you get the virus like that.

Strange amount of energy on heroin

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- Wed, 04 Mar 2020 19:48:45 EST Mjy8E5PD No.613990
File: 1583369325246.jpg -(37114B / 36.24KB, 680x406) Thumbnail displayed, click image for full size. Strange amount of energy on heroin
So I've done heroin a handful of times but I've found that it has a weird effect on me. If I do enough of course I will just be a nodding couch potato not doing much but nodding hard. But if I do less than that (enough just to feel good), I find myself having a lot of energy. Like I'll go around cleaning the apartment spotless or other weird shit like if I were on stimulants or something. Anyone else get like that or any other abnormal behavior on opiates you all have?
1 posts omitted. Click View Thread to read.
>>
Hugh Cidgeford - Wed, 04 Mar 2020 23:52:02 EST Mjy8E5PD No.613993 Reply
>>613992
Thanks. I'm a bit of an opiate novice so I wasn't sure if this might have something else in it or if it was normal like you just said. cheers and love m8
>>
Eliza Gimbleham - Thu, 05 Mar 2020 09:50:13 EST iC2qwFu7 No.614002 Reply
Thats normal with stuff like heroin, morphine(to a much lesser degree) and oxy, to a much higher degree.

But thats a testament of the quality of the euphoria, dogshit rcs like fent dont do that.
>>
Cedric Connerneck - Thu, 05 Mar 2020 10:26:27 EST ZSF+sx0n No.614005 Reply
1583421987245.jpg -(304552B / 297.41KB, 1280x1280) Thumbnail displayed, click image for full size.
I've heard the same about Kratom and that the southeastern asians mostly take it more as a mild stimulant than anything else.
That may be a somewhat different effect as far as how the drug is working, but I think just not having any pain and feeling a nice little buzz is enough to perk you up for the days activities more than maybe you'd usually be.

Same if I take a lower dose of benzos. Technically it's sedating, but the burden of anxiety being lifted is itself enough to cause an increase in my activity at a lower dose than it takes for the sedative effects of the drug to knock me out or pin me to the couch.

Synthetic opiates

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- Sun, 01 Mar 2020 22:03:44 EST ULsIYTPl No.613942
File: 1583118224236.jpg -(1107262B / 1.06MB, 3584x2134) Thumbnail displayed, click image for full size. Synthetic opiates
Is kratom the best legal opiate like thing available? By this I mean the only one that wont show up on a drug test? Heard of U47700 and what not any advice?
5 posts omitted. Click View Thread to read.
>>
Wesley Dommerspear - Tue, 03 Mar 2020 10:55:33 EST AYlrp4ua No.613967 Reply
>>613966
I appreciate the explanation. I think I will be okay as long as I pace myself and don't do more than once or twice a month. Opes are my favorite type of substance, but I have never been addicted to them. I have always been really careful with them even though I have done some pretty serious ones, including H and fent. I can't take anything else because I get tested anyways, and kratom is terrible. I have done over 10 grams of kratom in a single sitting and it did fuck all.
>>
NOD - Tue, 03 Mar 2020 21:49:44 EST ULsIYTPl No.613976 Reply
>>613942

drugs can't show up as opiate on a test so tram will show i believe
>>
Albert Chullylock - Tue, 03 Mar 2020 22:57:05 EST SUNa8wVi No.613977 Reply
>>613967
Tia is fine if you don't abuse it, it's only the WD/abuse potential that sucks really.

Sticking to a couple times a month sounds good, with it's short half-life that shouldn't cause issues. Just be very careful to not convince yourself "one more day wont hurt". You've been there before, you know for a fact it will. Don't get yourself addicted to tia.

AFAIK it doesn't show on tests either so you're fine there

Noob helping non-noob

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- Tue, 25 Feb 2020 12:02:01 EST RBBN/9yH No.613799
File: 1582650121974.jpg -(41488B / 40.52KB, 720x720) Thumbnail displayed, click image for full size. Noob helping non-noob
Someone dear to me is going to try to kick their heroin addiction and I want to be there to help them thru it. What can I expect, how can I make it easier, aaaaaand will he not want to have sex during this time? 😥 your suggestions, please. Thank you.
24 posts and 5 images omitted. Click View Thread to read.
>>
Rebecca Toothood - Tue, 03 Mar 2020 13:16:25 EST JD/7JWNJ No.613968 Reply
>>613862
Strong disagree on the “safe” part. There are much better options to consider than poisoning yourself and possibly causing cardiac damage with a hero dose of an OTC drug. You’d be better off getting on subs and doing a short term taper if anything.

Source:
https://www.tandfonline.com/doi/abs/10.3109/15563650.2014.969371
https://www.sciencedirect.com/science/article/pii/S019606441630052X
https://www.tandfonline.com/doi/abs/10.3109/15563650.2016.1159310
>>
Archie Buzzwater - Tue, 03 Mar 2020 15:47:15 EST fncd//z5 No.613969 Reply
Yea lope is terribly toxic and should be avoided, Gabapentin at 300mg-600mg twice daily is great for taking the edge off without trading one addiction for the other. Benzodiazepines, like 20mg valium a day, should be avoided to avoid trading addiction for addiction, but will really help take the edge off too.

Clonodine is an absolute godsend for taking care of the physical side, but it may be hard to get a script for.
>>
m - Tue, 03 Mar 2020 15:56:30 EST vgHBTjMI No.613972 Reply
>>613968
Subs cause precip WD and lope doesn't. One is available on store shelves and the other requires a connect. They're not really comparable. If you can hop on subs within just 24-48hr of using, then it's debatable whether your dependency is even that bad. When subs aren't an option and kratom won't cut it, lope is the only easy to access option.

I specifically said doses of 16mg or less/day spread out, NOT "hero" doses. It's not like you're forced to take 100mg like an idiot.

Opiate naive

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- Sat, 29 Feb 2020 16:18:17 EST oW4C6oxb No.613915
File: 1583011097615.jpg -(44151B / 43.12KB, 498x374) Thumbnail displayed, click image for full size. Opiate naive
Would it be inadvisable for someone who is opiate naive to try kratom? is this a gateway into a land that will fuck me? or is the risk pretty low?
6 posts omitted. Click View Thread to read.
>>
DTMO - Mon, 02 Mar 2020 01:24:30 EST 6GHvrNL7 No.613946 Reply
12.jpg -(80085B / 78.21KB, 666x69) Thumbnail displayed, click image for full size.
>>613945
>Serotonin syndrome

While Tripsit and many other resource will say the combination of MDMA and SSRIs is likely to cause serotonin syndrome, in practice SSRIs (when taken regularly, once your brain has adapted to taking them) tends to make MDMA feel like an uncomfortable amount of caffeine, it's basically impossible to roll if you're on them. If you don't take them regularly then taking MDMA with an SSRI for the hell of it is a pretty bad idea and may well be risking serotonin syndrome.

The effects of LSD are reduced when on an SSRI and there is no real risk of serotonin syndrome.

>>613940
>NON-INHALED cannabis

You're really laying it on thick today. You could at least try to explain why smoking/vaping weed is more addictive (I'm guessing you mean because it's basically instantaneous in effect?) if you want this to be taken seriously.

>MDMA

For what it's worth (and by the way I'm not singling you out Dr M, when I disagree I disagree it's it's not personal) I have found MDMA to be the worst for my depression in the short term. Worth it once or twice a year but the fortnight of feeling like shit afterwards is a bit much to do regularly. Maybe the comedown is a good thing in terms of addiction though, it certainly puts me off doing it on the reg.

Also, what do you mean by "nuture-related evironment"?
>>
DTMO - Mon, 02 Mar 2020 01:27:35 EST 6GHvrNL7 No.613947 Reply
1583130455970.png -(1361459B / 1.30MB, 1600x1600) Thumbnail displayed, click image for full size.
>>613946
Oh ffs. If there's an admin around please remove that image I posted. I meant to use pic related.
>>
m - Mon, 02 Mar 2020 17:41:26 EST vgHBTjMI No.613955 Reply
>>613946

>SS

Yeah SS is usually overblown. My understanding is that the biggest risks are when you've either started SSRIs/switched SSRIs/increased dosages in the last 30 or possibly 45-60 days, when your SSRI has a very long half life and you take it daily without having reached full bioaccumulation in the last 30ish days, or when combined with a drug that directly releases serotonin, not when combined with another SSRI-esque drug, especially if the other drug functions like an SSRI but has less binding affinity.

That being said, I'm pretty sure MDMA releases serotonin directly, and does so at a significant rate. It's not like you're guaranteed SS every time, but relatively speaking, MDMA certainly has at least a moderate risk relatively. The risk outright in terms of actual chance of SS is still relatively low for those on somewhat low dose, moderate or shorter half-life SSRIs, who have been stabilized on their dose for a few months, assuming we're talking say 100mg or maybe 150mg MDMA, but it's all guess work.

>varying degrees of cannabis habit forming behavior

Surely you'd agree there's significant established literature finds concerning IV and inhaled drug use of almost any category being more mentally addictive/habit forming than slower onset routes. While cannabis might be weaker than almost any moderate or "hard" drug in this regard, anecdotally it still holds true for myself and many I know. While the mental draw to smoke/vape is extremely weak when one hasn't done it in months, those actively using tend to pseudo-fiend for cannabis much more when their primary method is by inhaling. All I can say is that after I convinced 4 friends to give it a try by using up all flower/concentrates and replacing them with oral doses, 3 of them have stopped using daily altogether, and the other uses a lot less than before. 2 of them have said they have stopped thinking about it as soon as they get home from work. In my personal life, making the switch has lead to me not consuming any THC for well over 6 or more months.

>"attacking" me
I dont take it personally. You're free to express yourself just like me. We need continual dialogue to keep this place from turning to shit.

>MDMA being a bad choice for depression
Absolutely. I wasn't suggesting it as a good choice to try. It's simply much less likely to lead to mental addiction, let alone near daily use.

>nuture-related environment
It was simply an extra indication as to the difference between our environment and our genetics. The main theme was that genetics are what matter most, and environment can always change.

Using less water in a shot cause a better high

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- Wed, 26 Feb 2020 12:46:26 EST TYzQZ0jK No.613816
File: 1582739186028.jpg -(4477B / 4.37KB, 480x360) Thumbnail displayed, click image for full size. Using less water in a shot cause a better high
Hey all, if I use less water in my shot of heroin will I feel it better? Like I mean when I draw up the water use less water so it's thicker will that cause a difference vs it being alot of water and the solution is basically clear?
4 posts omitted. Click View Thread to read.
>>
Martin Sunningstone - Sun, 01 Mar 2020 05:22:46 EST gE8yyxax No.613932 Reply
>>613816
Can fit plenty into 1ml just filter as slowlt as you can if u dont micron

Its more how fast you gwt the shot in ur veins i.e. plunger speed than amount of watet.unless its like 100mg mst in 10ml water from sterile mst amps ect
>>
Archie Hannertedge - Sun, 01 Mar 2020 09:02:43 EST JD/7JWNJ No.613935 Reply
>>613845
The difference would be marginal to the point of nonexistence. The potential cost of using a dangerously thick solution or trying to jam down the plunger *vastly* outweighs any potential benefit.

Oxycodone + weed

View Thread Reply
- Fri, 28 Feb 2020 04:40:59 EST uEHpumuQ No.613882
File: 1582882859277.jpg -(64117B / 62.61KB, 720x711) Thumbnail displayed, click image for full size. Oxycodone + weed
/wooo/ says hi!

Had a knee surgery 2 days ago and I got some Targinic (oxycodone+naloxon) for the pain and was thinking I really wanna try one with weed. Is there any risk combining opiates and weed together?
6 posts omitted. Click View Thread to read.
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DTMO - Sun, 01 Mar 2020 00:48:14 EST 6GHvrNL7 No.613924 Reply
>>613882
I don't know when this board turned 50, but to answer your actual question weed doesn't increase the risk of respiratory depression. Whether it's a good combo is pretty subjective but some do like it.
>>
Frederick Nupperworth - Sun, 01 Mar 2020 01:00:25 EST wYewymhh No.613926 Reply
>>613924
People here are way more fucking stupid than I remember them being back in 2013-2015.
>>
Dr. Katz !KqgSR25gAQ - Sun, 01 Mar 2020 04:59:50 EST KnL4ajYu No.613929 Reply
>>613882
Dang, OP. /opi/ + /weed/ is godly. DO NOT abuse the combo too often. Too, take the drugs together a few times before you ever want to be in public while under the influence (i.e. high in public, but not driving).

Suboxone, tolerance, and comparison with other opi

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- Thu, 27 Feb 2020 18:28:03 EST l/QqfqV/ No.613864
File: 1582846083024.jpg -(36529B / 35.67KB, 675x672) Thumbnail displayed, click image for full size. Suboxone, tolerance, and comparison with other opi
I've been taking 8mg/2mg Suboxone strips fairly regularly for a couple months now, about 2-3 times a week. I cut them up into 3rds or 4ths and they still get me somewhat high.

However, I want to experiment with something stronger, so I have some 30mg oxycodone on the way. How fucked is my opi tolerance? How long should I stop use of Suboxone before I take the oxycodone to get a decent high? How long does IR oxycodone last in comparison with Suboxone?

I also have the ability to purchase H, how long does a gram typically last if insuffalated? I know almost nothing when it comes to H

sorry for many questions, thanks
8 posts and 1 images omitted. Click View Thread to read.
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Molly Murdford - Fri, 28 Feb 2020 12:53:14 EST l/QqfqV/ No.613895 Reply
>>613881

Thank you for the answer friend. I was thinking waiting a good 2 weeks would be sufficient. Mainly concerned about the naloxone but it should be fine.
>>
Frederick Worthingshaw - Fri, 28 Feb 2020 17:46:08 EST IxGcrMpY No.613897 Reply
>>613895
naloxone isnt anything. like above, its the bupe you need to avoid. someone overdosing on heroin can be revived with buprenorphine because it will knock the heroin off. The naloxone is just a meme patent scam essentially.
>>
m - Fri, 28 Feb 2020 18:29:26 EST vgHBTjMI No.613898 Reply
1582932566268.jpg -(31391B / 30.66KB, 600x412) Thumbnail displayed, click image for full size.
>>613895
The naloxone isn't even relevant in your case. Naloxone only matters when it comes to switching from a full agonist to bupe+naloxone, and even then it ONLY really matters if you're inducing micro/low doses, like ~1-2mg in particular, or I guess possibly up to 4mg bupe, and ONLY if you use it via IV, I guess IM/SubC, and to about half the extent if you snort or boof it. EVEN THEN, its impact is debatable, not experienced by everyone, and even if it is noticeable, it's relatively marginal.

Bupe displaces full agonists, which causes precip WD if you're dependent. If you induce say 0.5mg of bupe via IV (~1.5mg or so sublingual equivalent), you also IV 125ug of naloxone. That means that (making up a fake number to show my point) if say 0.5mg IVed bupe alone would normally displace say 33% of receptor sites, if basically all your receptor sites were occupied by say oxycodone, it would cause (at least on "paper," experience isn't linear) 33% of the max precip WD causable by a full bupe replacement on your receptors.

By since only 33% of receptor sites would be displaced, that means the additional 125ug naloxone would have access to additional undisputed oxycodone-activated receptor sites, allowing the naloxone to in theory cause additional precip WD. And on paper, something like naloxone/naltrexone should cause worse precip WD symptoms than bupe, assuming they occupy exactly the same quantity of receptors.

Now it gets more complicated because it's not entirely clear if naloxone truly has a subjective threshold "requirement," or if such threshold is different when combined with bupe and a full agonist in a vacuum compared to just oxy and naloxone. Either way, according to at least one source I read, just ~0.2mg naloxone IVed is capable of causing precip WD, at least without bupe around.

Supposedly something like ~8mg bupe via SL use (or in theory ~24mg if taken orally via intact tablet/film without dissolving/being kept in the mouth), ~5-5.33mg snorted/boofed, or ~2.5-2.67mg IVed occupies ~80-90%+ of one's receptors, and that's assuming no previous bioaccumulation from previous doses. The more receptors are replaced with bupe instead of say oxy, the fewer receptor sites are conveniently available for naloxone. Once you reach ~90%+ bupe receptor saturation, pretty much all the conveniently available receptor sites that were either entirely empty of exogenous opioids or occupied by oxycodone have been replaced.

So just about any receptor sites that might have had oxycodone ripped off and replaced by naloxone, would in turn be ripped off and replaced by the bupe.

>tl;dr
naloxone in suboxone only really is even possible of making a difference if you're already physically dependent on a full agonist and therefore at risk of precip WD, only if your bupe doses are below 4mg sublingual equivalent (possibly below 6-8mg to a much lesser degree), and ONLY if you snort, boof, or inject suboxone. Snorting or boofing the naloxone portion of suboxone is only capable of causing roughly half the potential marginal WD as IVing it mg for mg, and even then it's less sudden.

Even then, we're talking such marginal effects. I personally didn't notice any difference between suboxone and subutex when dependent on PST in the past, whether subbed, snorted, or boofed.

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