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420chan is Getting Overhauled - Changelog/Bug Report/Request Thread (Updated July 26)


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- Wed, 28 Aug 2019 17:15:46 EST tgJwbVH+ No.609881
File: 1567026946789.jpg -(1656296B / 1.58MB, 3024x3024) Thumbnail displayed, click image for full size. Tramadol
What's up with all the tramadol?
That drug is the lousiest opiate around
And dangerous too
I prefer kratom any day
Of course I do like the convenience of pills
Not so much that I would take tramadol though
2 posts omitted. Click View Thread to read.
Kekistan69 - Thu, 29 Aug 2019 16:39:11 EST JEt2x1Cb No.609902 Reply
I'm with OP. After building up an insane tolerance to opioids numerous times, and quitting numerous times, I just switched to Kratom. Idk if he works for everyone but I get a good mild opioid/mild stimulant buzz from Kratom everytime I dose (which is 6-7 times a day at small doses). Kratom tolerance does not continue to rise continuously the same way typical opioids do.
Molly Smalllock - Fri, 30 Aug 2019 16:00:27 EST cbXJ46oj No.609924 Reply
haven't tried it with tolerance but I enjoyed the buzz quite a bit. I've gotten infinitely higher from trams than any kratom I've tried (yes, I got good shit and this was before I had a tolerance).
i'm also sorta a little depressed sometimes so maybe I get more out of that part of it (although I thought most common antidepressants these days need a few weeks to show an effect but maybe that's for a different kind).

but yeah, cheap as dirt, most people don't think much of it and it's prescribed easily and more readily prescribed along with benzos, which is normally hard to pull off.

quetz mentioned the genetics thing but the other quirk is that a tapered dosing schedule actually gets you more odsmt than taking it all at once, in direct defiance of the typical wisdom that you should take your entire dose at once for the best effects.
Molly Smalllock - Fri, 30 Aug 2019 16:06:29 EST cbXJ46oj No.609925 Reply
kratom tolerance definitely rises... maybe it has a ceiling but go to any kratom internet forum and there'll be about a million topics about reducing tolerance cause they can't get high anymore or people doing 10+g doses and whatnot. also, dosing 6-7 times a day doesn't really help your point at all, lol. kratom is definitely better than good opiates to be addicted to, as far as wds, safety, and supply but be real about it.


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- Mon, 26 Aug 2019 20:12:12 EST +YqNcs0a No.609844
File: 1566864732926.jpg -(8036B / 7.85KB, 200x200) Thumbnail displayed, click image for full size. Butyrfentanyl
What would be the best way to mix 5g of butyrfentanyl with mannitol for IV/smoking?
David Mucklekodge - Tue, 27 Aug 2019 08:05:43 EST ESCXnZgl No.609854 Reply
1566907543913.jpg -(23250B / 22.71KB, 644x598) Thumbnail displayed, click image for full size.
You have to mix it in a liquid. You do not need mannitol. You need volumetric dosing.
Example is mixing 100mg in 100mL of water to get a 1mg/mL solution. If that's too strong take 10mL of 1mg/mL and mix with 90mL of water. No you have 100mcg/mL. And so on until you have 50% of your syringes' volume carrying your ideal dose. Then you have a solution you can do less or more of pretty easily.
Example if you want 50mcg dose, in your 100IU syringe, you would use that 100mcg/mL or 100mcg/100IU solution, and use 50IU.

If you really just *have* to smoke it, you could spray that solution onto weed or whatever medium your using to smoke it and make single doses, but never more than single doses because of hot spots in the dried mix.

If all of that didn't make sense or seems really too complex, then you can't do fent. You must master that technique before you dabble. Also ButryFent is shit and isn't nearly is dangerous as real fent. IIRC its like in the 50-100mg dose range for non-naive users. But its still risky if you get something that is poorly mixed fent being sold as safer butyr fent.

I haven't shat in 8 days

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- Thu, 22 Aug 2019 17:09:23 EST 9bMGWRoI No.609749
File: 1566508163392.jpg -(4993B / 4.88KB, 193x198) Thumbnail displayed, click image for full size. I haven't shat in 8 days
I feel like I swallowed a bag of buckeye marbles and they're just rolling around in my guts. I'm bloated and feel like I have to piss, but it's not, it's just weight on my bladder. I managed one single nugget today which was.. not enough. it was about the size and shape of a chestnut.

I'd say it's the opiates but I don't think I do them that frequently... BUT I have been using them to not eat because they're great for that, so I got a bit of a double whammy here. I'm eating a literal bucket of spinach to try and get things going.

What's the longest you've gone without shitting?

what's uh the longest 'safe' time to go without shitting like when should I go to the doctor / get an enema before I die lol
14 posts and 1 images omitted. Click View Thread to read.
hsn - Mon, 26 Aug 2019 11:37:05 EST cA+802PK No.609830 Reply
once you hit the two week mark shit starts to get real, like you cant perform daily functions anymore and eating induces nausea since you are bursting at the seams.

if you are desperate, and I mean ONLY when you are desperate, chug two bottles of magnesium citrate liquid and on god I swear itll cure your anus probs. just be prepared to be shitting skr8 liquid for the next 2-3 days while your body adjusts into the maternity stage after birthing such a mass.

also I notice I get the worst constipation when I am not drinking enough liquids so make sure to stay extra hydrated no matter what.
Martha Smallworth - Mon, 26 Aug 2019 13:34:39 EST 41cJEaaF No.609831 Reply
Ideally you should be staying hydrated predominately. If that fails, buy a bottle of DXM only cough syrup, chug it with some coffee and smoke some cigarettes. These three things combined are sure to get you purging. Hope you're not dead OP! The longest I've ever gone without shitting was probably around 3 days. Interestingly, back when I ordered some Canadian codeine I had an incredibly frightening episode of urinary retention. I thought if I chugged enough water I would be able to go, but it actually just made the pressure and pain twenty times worse. I ended up checking myself into the ER and getting catheterized. The tube being shoved up my dick felt really weird, but the subsequent release of all that urine felt wonderful. I went back to the hospital the next day to have the catheter removed.
Molly Smalllock - Fri, 30 Aug 2019 17:35:42 EST cbXJ46oj No.609932 Reply
>buy a bottle of DXM only cough syrup, chug it
I'm going to recommend nobody do this because it sounds terrible and I can't see how it would help at all, unless you want to throw up.
like there is no problem where I think "yeah, let's throw a DXM trip on top of this, that'll make things better" especially something like this, but maybe that's just me.

Advice Withdrawing off the Fake M30s

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- Sun, 25 Aug 2019 00:21:47 EST HtQLHF8I No.609803
File: 1566706907579.jpg -(116575B / 113.84KB, 640x767) Thumbnail displayed, click image for full size. Advice Withdrawing off the Fake M30s
I've been using the fake M box blue oxy pills for about 4-5 months now. They are the ones pressed with fentanyl, the withdrawal usually begins around 4 hours from the last dose. Now here is the deal with my tolerance, I always see other posts from people saying that they are taking up to 3 a day like it's a huge amount, that is nothing to me. For the last week I have been using about 10 pills a day, sometimes a little under or a little over. I usually start using when I wake up and redose every 1-3 hours or so until I go to sleep.

So what has me worried is I never see any one else talking about having this much tolerance or using this many of these per day. Does anyone here have any experience with this? Would be helpful to hear from even one person who had experience with tolerance like this, and how they got out of it. Also any tips on getting through the withdrawal will be appreciated. I am wondering if I can possibly taper down before going cold turkey.
2 posts omitted. Click View Thread to read.
Samuel Murddock - Sun, 25 Aug 2019 06:09:26 EST ZZZzwdbx No.609807 Reply
I was addicted to pure fentanyl dosed in a nasal spray for over a year and a half straight. I tapered down a lot by continuously diluting my nasal spray after every x amount of sprays. After that I just buckled down and cold-turkeyed that shit because opiate withdrawal will not kill you regardless of your tolerance.
Fuck Farryhut - Sun, 25 Aug 2019 12:19:47 EST OHIHxMID No.609813 Reply
This. It’ll be tough to wean with fake shit but regardless you are going to have to WD at somepoint and it’ll suck. Just be glad it’s not from benzos which you should try to obtain with other comfort meds.

Should I assume my dumb decision is H?

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- Thu, 15 Aug 2019 05:19:07 EST VkyM8MkQ No.609440
File: 1565860747336.jpg -(198630B / 193.97KB, 3008x1960) Thumbnail displayed, click image for full size. Should I assume my dumb decision is H?
Found some powder in a users room when I visited a house I had to do something at. Took a gel cap filled with chunky white powder which I assume is scramble H. And some small thin glas vial with a plastic topper on it not sure what it was but pretty sure it was some opiate as we. Been binging lil bumps every couple hours. Feels like an opiate. Tried to test em with my mandelin kit. But I think its bad due to its a couple years old. Liquid is a nasty brown color now.

Feels like an opiate but I havnt been going to full nods but I cant keep myself asleep for more more than a couple hours. On east coast by baltimore. I seem fine and high, itchy and tiny pupils. Should I assume its h?
10 posts omitted. Click View Thread to read.
Phyllis Buzzcocke - Mon, 19 Aug 2019 20:45:46 EST cbXJ46oj No.609663 Reply
I mean, after that thread about the dude going on like a mini rampage or the thread about kidnapping/being kidnapped (i forget the deets), trying to be a voice of morality here is sort of like pissing into a hurricane. Is it the right thing to do? of course. will you end up covered in piss and also probably dead from being in a hurricane? absolutely. has this analogy gotten away from me? definitely. in conclusion, I completely agree with you but I've given up on trying to give people advice or judgement (not that you should give up, at least someone on here should call people out for their dumbass junky shit).
Beatrice Briblingleg - Sat, 24 Aug 2019 04:40:38 EST 4dTnJKkc No.609787 Reply
No doubt man, I agree with you too; I'm not the voice of morality here or anywhere else. I've done shitty stuff myself, like everyone, I can't judge anyone for shit, but...There's a big asterisk there: I've done shitty stuff..*While sick as all hell*. This faggot ass jerkoff cleary has no habit. And even when flopping around like a fish coated in sweat, I'd pinch some I got for someone else(pretty much a given though, really..) but I've never and never will burn someone with a habit. Really makes my blood boil, and a guy with a vial and cap laying around in Baltimore..I'm gonna guess he gets sick(see: he lives in Baltimore). I dunno, is what it is I guess, but fuck OP. Sorry, Op; but fuck you.
Phineas Furrygold - Sat, 24 Aug 2019 17:44:16 EST rMoGgOJh No.609794 Reply

If he is any kind of "real" junkie, he will know exactly how much he has and will notice if any of it is gone. He'll put 2+2 together and will be extremely pissed off, with good reason.

I hope for your own sake you don't know him and he doesn't know you or you are unlikely to ever see him again

basic intravenous safety guide

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- Thu, 22 Aug 2019 02:04:06 EST CVn32EyS No.609727
File: 1566453846376.jpg -(76577B / 74.78KB, 768x768) Thumbnail displayed, click image for full size. basic intravenous safety guide
stericup or other cooker(http://www.totalaccessgroup.com/stericup_colored.html)
cotton filters, must be tightly packed, you don't want to inject strands of cotton(http://www.totalaccessgroup.com/Cotton_filters.html)
alcohol prep pads(https://www.amazon.com/Dynarex-Alcohol-Prep-Sterile-Medium/dp/B005BFL0RQ/)
iodine prep pads(https://www.amazon.com/Iodine-Prep-Pads-Individual-Disinfecting/dp/B079VZ6YMG/)
1cc insulin syringe(https://www.amazon.com/BD-Ultrafine-Insulin-Needle-1-Markings/dp/B07C96LS75/)

optional/ situational:
sterile citric acid(https://www.exchangesupplies.org/shopdisp_sterile_100mg_citric_acid_sachets.php)
syringe filter

add your material to be injected to your stericup, you may want to as well add citric acid or an alternative to help put your substance into solution, highly recommended to be very light with the amount of citric acid you add as it can cause damage to your vein as well as cause general discomfort
add an amount of water so that it becomes saturated, stir well
apply heat under your cooker and continue to stir
once the powder/ tar has been completely dissolved, drop your filter into the cooker, if your filter is at all torn or frayed, it's advised to use a different one
tip the cooker slightly as to make sure the filter is saturated
press your needle firmly against the filter and slowly draw the contents of the cooker into the needle
hold the syringe upright and flick or shake the syringe slightly as to raise any air bubbles to the top, press the plunger slightly until several drops of your solution have been ejected
sanitize your injection sight with iodine and or alcohol
if a tourniquet is desired, apply now
slowly insert the needle into the desired vein, pull the plunger back to be sure that you're fully into the vein, if using a tourniquet, release it now
press the plunger down slowly and steadily
apply pressure and a bandage
dispose of used injection materials

iodine is an oxidant which prevents the growth of anaerobic bacteria, if you ever receieve a surgery where a large incision is made, an iodine solution is applied to the incision site!
citric acid may be required with tar to put it into solution with water
Comment too long. Click here to view the full text.
2 posts omitted. Click View Thread to read.
hsn - Thu, 22 Aug 2019 12:24:33 EST cA+802PK No.609740 Reply
most people dont have access to micron filters...cotton is the most common. they hand out cotton at many needle exchanges and whatnot. hes not wrong at all.
Thomas Crommlestock - Thu, 22 Aug 2019 18:09:33 EST xScyS6ln No.609753 Reply
Good thread but the real question is where's the step by step to getting Bailey J high off her tits on H so I can get up in her guts.
Ernest Wubberpire - Fri, 23 Aug 2019 15:22:39 EST hsSi6Hrd No.609771 Reply
Haha! Love this comment! Ahh Baily.... I almost forget sometimes that this person is a TS...

Sleep during WD

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- Sun, 18 Aug 2019 10:07:15 EST cFO37f8I No.609599
File: 1566137235656.jpg -(70717B / 69.06KB, 480x600) Thumbnail displayed, click image for full size. Sleep during WD
Whats yalls sure fire way of sleeping during WD? Its honestly the worst part for me, i wish i could skip the time
10 posts omitted. Click View Thread to read.
Basil Bruffingwill - Thu, 22 Aug 2019 10:26:07 EST +rJY0K/n No.609738 Reply
Aside from the obvious more opi and benzos try to excercise what you can manage. It’s easier to sleep during the day if you’re home. Everything seems to get worse at night especially with RLS (at least for me). If at your disposable though clonazolam was the only thing that worked better than kratom during WD. Kratom just takes the WD sometimes with a mild buzz but the clam completely overrode the WD and got me to the point I couldn’t keep my eyes open. Shit last so long too if made it possible to go to work the next day without redosing when I woke up only 24hours later. But it’s also pretty easy to blackout and miss work completely on that shit.
Priscilla Heppershit - Thu, 22 Aug 2019 10:29:55 EST OHIHxMID No.609739 Reply
Oh yeah. Long hot baths also help me a lot. And you guys will probably laugh at the thought of this one but I use my heating pad on my pillow for extra comfort. I usually have it on anyways but when in WD it seems to help relax me if I put my head on it rather my back what I primarily use it for.

Questions about OXYNEO 40mg ER

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- Wed, 21 Aug 2019 13:44:07 EST QyExqGSP No.609711
File: 1566409447692.png -(12541B / 12.25KB, 174x66) Thumbnail displayed, click image for full size. Questions about OXYNEO 40mg ER
Hey Opi, so I got a plug for some oxy.. I've been trying to score since I lost my script a few months back. So the oxy I have access too is from an older lady, with a script. They're Oxy Neo 40mg ER.

I'm not sure what to think, first of all I have basically 0 tolerance. Secondly, when I had a script it was for 5mg oxy IR. I was used to taking 15mgs of that.
This raises some questions for me hopefully yall could give me some insight on - I heard oxy neos are hard to split - because I wouldn't be dosing the full 40mg.. or at least I don't think so. Which leads me to my second question, if I was used to dosing 15mg IR every 5-6 hours - what will be the difference that I need to make up with these 40mg ER. They feel the same, but how does it come on? It lasts for longer, so will that mean it's a weaker high? If so, should I be dosing higher? I really don't want to go above 20-25mg for my first doses, because I dont want the tolerance build up so quickly & I don't want to risk anything.

Appreciate any help, thanks guys.
4 posts omitted. Click View Thread to read.
Dextrolord - Wed, 21 Aug 2019 23:55:29 EST t9+obISS No.609724 Reply
Just to piggyback on thants, I used toenail clippers, bought a new pair and they never touched any actual nails lol, to chop up my opana ERs back in the day and that worked perfectly
dr. m - Thu, 22 Aug 2019 06:49:46 EST jSts+8cD No.609733 Reply

Just break off the amount on the tablet you would want to take if it was the normal IR. Then crush that piece up best you can. Then drop it in a shot glass filled with normal coca-cola, not diet. Then wait ~8-16hr for it to dissolve. You can simply use citric acid mixed in water instead if you have it.

Once it's fully dissolved after ~8-16hr (no idea how long that specific formula takes to dissolve), simply drink the shot of coke, then refill shot glass with water, swirl it around, and drink any leftover goop/gel/residue. And that's how you turn it into roughly ~75-80% instant release and ~20-25% leftover extended release. Also, try to haggle them down to $20. They're XR after all.
Barnaby Hissledock - Thu, 22 Aug 2019 09:51:07 EST j04k2rVa No.609736 Reply
to my knowledge er/xr are aame amd cr/sr are the same, but as i said, cr/sr gives a continual amount and er/xr gives different amounts at different times. maybe should be looked into.

100 mcg/hour fentanyl patches

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- Sat, 17 Aug 2019 18:11:15 EST 0DBMiwu4 No.609555
File: 1566079875777.jpg -(58239B / 56.87KB, 510x680) Thumbnail displayed, click image for full size. 100 mcg/hour fentanyl patches
I have some 100 mcg/hour fentanyl patches.
I want to get high on them. I take 400mg of codeine every day and have done for several months. 400mg of codeine doesn't get me high at all anymore, maybe a small buzz for about an hour.
I'm planning on cutting one of the patches into quarters and applying it to my skin so I get a 25 mcg/hour dose of fentanyl every hour.
will that be enough to get me high?
14 posts omitted. Click View Thread to read.
Thants !IZgeXR9w82 - Tue, 20 Aug 2019 13:47:14 EST OgX3IMCX No.609686 Reply
>I've never heard of someone dying from fent patches specifically from the way the fent was unevenly distributed.

How could anyone deduce that posthumously? I'm not trying to argue with you but that's an unknown unknown. Unless the user somehow stated before use and OD/death that they were aware of other factors like potency and/or similar aspects.

Although I can't remember my source for this information I do remember reading something about medication in tablet form having only to be evenly distributed if the pill is scored to be broken in half. Then again I see pharmacists chopping N8 subs in half and giving people 4mg doses at the clinic and i know those pills aren't scored so that kind of removes the legitimacy of what I just said.. who knows.. I could see gel reservoir patches being unevenly distributed because you can literally move the gel around inside the membrane by placing it flat on a table and pushing on it with a plastic card.
dr. m - Tue, 20 Aug 2019 14:19:45 EST qsHN3Ndz No.609688 Reply

IMO the bigger problem isnt if it's evenly distributed or not. The problem is that cutting it, at least for the OG gel patches, caused a higher absorption rate than normal because of the edges oozing gel.

OP, dont gum them. Using them nasally or rectally is over two as efficient. Look up sublingual and buccal bioavailability percentages for buccal (on the gems) fent. Its only like 30-40% IIRC. Meanwhile, nasal is ~89% and rectal is presumably 90%+.
Clara Penderson - Wed, 21 Aug 2019 14:56:36 EST 6vyTjX1P No.609716 Reply
Yo OP use basically this method

chop it up into small bits and eat it like you would acid

Wanna kill oxy high, will IN suboxone work?

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- Mon, 19 Aug 2019 21:57:38 EST aZ667T0e No.609670
File: 1566266258435.jpg -(73655B / 71.93KB, 1125x808) Thumbnail displayed, click image for full size. Wanna kill oxy high, will IN suboxone work?
So ive had some oxy today, i dont normally use oxy but now i wanna have a few drinks b4 bed. Im not very high, but im wondering if i can use suboxone to kill the effects of oxy to counter potential resporatory depression. Does that make sense?
4 posts omitted. Click View Thread to read.
Shitting Dosslepag - Wed, 21 Aug 2019 13:57:24 EST Va7/tQEi No.609712 Reply

Nah I agree with you I just didnt quite get it and imagined some stuff lol

Does anyone have that "i sold my dog" thread saved??!!

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- Mon, 19 Aug 2019 17:13:36 EST I/ST301X No.609653
File: 1566249216824.jpg -(18426B / 17.99KB, 300x168) Thumbnail displayed, click image for full size. Does anyone have that "i sold my dog" thread saved??!!
Please please please. It was maybe from 4 or 5 years ago? Please I know someone must still have that thread saved. Or at least an image capture of it. The dude sold his family's dog!
7 posts and 2 images omitted. Click View Thread to read.
Clara Penderson - Wed, 21 Aug 2019 14:45:07 EST 6vyTjX1P No.609715 Reply
aw shit I was here for that one, don't have it saved though
Thants !IZgeXR9w82 - Wed, 21 Aug 2019 19:05:02 EST OgX3IMCX No.609720 Reply
It's used to be in the 420chan archive as well on taima when it existed, I remember once being able to bring it up front page on google.

noob question

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- Tue, 20 Aug 2019 00:31:01 EST s8+dP9gR No.609675
File: 1566275461590.jpg -(58822B / 57.44KB, 480x640) Thumbnail displayed, click image for full size. noob question
Can I smoke opium in a crack/meth pipe? What kind of opium should I buy? Should I stick to just opiated hash? My body and soul hurt pretty bad, not sure if this is the right thing, but when I take the tea I can erase most of the fucking pain for a little while. Don't hug me, I'm scared.
Phyllis Buzzcocke - Tue, 20 Aug 2019 00:41:53 EST cbXJ46oj No.609676 Reply
if you are in America, don't buy any opium. best case it's overpriced heroin, worst case it's overpriced heroin with enough fent to kill you, medium case it's worthless incense.
Nigel Hommerdid - Wed, 21 Aug 2019 01:28:37 EST s8+dP9gR No.609703 Reply
Is there a cool place to go for opium tourism besides sunny, friendly Afghanistan?
dr. m - Wed, 21 Aug 2019 03:17:38 EST qsHN3Ndz No.609705 Reply

Yes. Laos mostly as well as Myanmar, somewhat Cambodia, and maybe vietnsm.

Using on vivitrol.

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- Sun, 18 Aug 2019 19:45:03 EST vxU1Ds4w No.609617
File: 1566171903239.png -(854334B / 834.31KB, 750x1334) Thumbnail displayed, click image for full size. Using on vivitrol.
Sup opi. So my question is what is the earliest day you can use on vivitrol and feel it. Yes I know all the risks involved in doing this. I’m on day 20 currently and haven’t tried anything yet but I know it wears off in 28 days but I got a toothache that hasn’t gotten any better so I’m trying to get some relief from shooting something. Thanks in advance 👍🏼.
1 posts omitted. Click View Thread to read.
Phyllis Buzzcocke - Mon, 19 Aug 2019 21:20:44 EST cbXJ46oj No.609668 Reply
must be some toothache
dr. m - Tue, 20 Aug 2019 18:43:29 EST qsHN3Ndz No.609695 Reply

I'm so sorry your....toothache...hurts so much you feel the need to shoot up. I used to tell people that you could try using suboxone/subutex because buprenorphine will break through naloxone, but that was before I found out vivitrol is naltrexone, not naloxone. Naltrexone has a stronger binding affinity than both buprenorphine and naloxone.

Your only hope is to wait until maybe day ~25-35 and use suboxone. This is because, while naltrexone will block just about any semi-common opioid, its half life is only 4-6hr. Naltrexone's metabolite is the one with the half life of like 13hr or something. Why is this important? Suboxone aka buprenorphine will break through naltrexone's metabolite, but not naltrexone itself. So towards the last few days or maybe a week of the vivitrol shot's effectiveness, it's possible that theres little to know actual naltrexone being released, and it's just the buildup of naltrexone metabolite that ensures that vivitrol remains effective for at least a full 28 days.

So tl;dr, you could try suboxone after around day 21 or later, but it likely wont work until at least 28-30 days, possibly 35+. However, suboxone/subutex is the most likely opioid to work towards the end of a month of vivitrol.

Honestly man, why are you even getting vivitrol unless it's court ordered? Personally I'd fight for sublocade instead.
Jenny Shittingman - Wed, 21 Aug 2019 00:21:17 EST LZ2GiWn6 No.609702 Reply
I used to wait till the 30th day off vivitrol and start shooting again for like a day or two and then get the shot again lol.

Potentiator Question

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- Sat, 17 Aug 2019 20:45:58 EST 7Teze97q No.609561
File: 1566089158857.jpg -(33241B / 32.46KB, 720x711) Thumbnail displayed, click image for full size. Potentiator Question
I've heard that hydroxyzine can potentiate opiates, but just how strong is the effect?
Nigel Sadgemotch - Sat, 17 Aug 2019 21:04:14 EST SnO3ZRr8 No.609562 Reply
I just got out of the ER a month ago (ish) with a perc RX and I am already prescribed hydroxyzine...

I didnt notice much of a difference...if you routinely take hydroxyzine the drowsiness isnt an issue anymore
Martin Brecklefield - Sun, 18 Aug 2019 23:20:30 EST U8xxeth7 No.609628 Reply
It's bullshit advice of desperate junkies and opi noobs. Antihistamines don't do shit. Mainly all they do is make you tired and dirty the high while removing energy and euphoria from it. Only reason anybody does this is trying to combat itching in desperate hopes of getting just anything for slightly longer legs on stomped on garbage. Don't even bother. If you have to mix it with anything mix it with pot. Or little bit of alcohol, if you have tolerance to both and aren't moron enough to OD.
Dr. Katz !KqgSR25gAQ - Mon, 19 Aug 2019 00:52:14 EST 56TOD6Vq No.609634 Reply
I think synergy is more so what you’re asking about. A typical potentiation technique for opiates involves inhibiting CYP3A4 with grapefruit or cimetidine (Tagamet), which has a rather significant reaction.

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