Leave these fields empty (spam trap):
You can leave this blank to post anonymously, or you can create a Tripcode by using the format Name#Password
[i]Italic Text[/i]
[b]Bold Text[/b]
[spoiler]Spoiler Text[/spoiler]
>Highlight/Quote Text
[pre]Preformatted & Monospace Text[/pre]
[super]Superset Text[/super]
[sub]Subset Text[/sub]
1. Numbered lists become ordered lists
* Bulleted lists become unordered lists


Discord Now Fully Linked With 420chan IRC

Beginner oral Morphine dosage? Both instant and XR?

View Thread Reply
- Fri, 29 Nov 2019 03:44:10 EST LUyYscjX No.612255
File: 1575017050312.png -(89153B / 87.06KB, 1080x608) Thumbnail displayed, click image for full size. Beginner oral Morphine dosage? Both instant and XR?
Hey guys I got some access to some morphine, both XR and instant release.
At what dosage should I start? Thanks guys.
5 posts omitted. Click View Thread to read.
DTMO - Wed, 04 Dec 2019 03:52:11 EST aRWRF2tE No.612339 Reply
>Morphine is technically 1:1 with hydrocodone in terms of analgesia, but so many people insist that morphine is notably weaker than hydrocodone mg for mg when both are taken orally.

No, it's 1:1 when via IV. Oral BA of both substances are vastly different.
DTMO - Wed, 04 Dec 2019 03:55:08 EST aRWRF2tE No.612340 Reply
I'm just saying it's not a matter of "many people insist" it's a matter of "look st any scientific data on the subject". It's readily available information and not speculative at all.
dr. m - Wed, 04 Dec 2019 17:17:20 EST LOk04uH3 No.612359 Reply
nope...let's take a look.


Equianalgesic Oral Doses (in mg):
Morphine IR : 30mg
Oxycodoe IR: 20-30mg
Hydrocodone IR: 30-45mg
Codeine: 200mg

It looks like somehow oral hydrocodone is listed as even weaker than oral morphine...weird. And I've always thought codeine is 10:1 codeine:morphine for oral use in normal metabolizing people.

Generally speaking, IV morphine is roughly ~2.23x stronger than oral oxycodone mg for mg (based on assuming of 30% oral BA of morphine, though it generally varies from ~20-40%). IV morphine is supposedly ~3-3.33x stronger than oral hydrocodone mg for mg, but I can definitely agree that's up for debate.

Let's be clear, though. 20mg of oral oxycodone IR is equal to 30mg oral hydrocodone IR which is also equal to ~30mg oral morphine, though logically that can vary by as much as ~20-40mg oral morphine given the high variability in oral BA (~20-40% BA variation when considering the middle 95% percentile metabolizers).

Now I don't disagree that 30mg oral hydrocodone has more recreational potential for most users than 30mg oral morphine, particularly for daily/near daily morphine users by merit of the fact that habitual morphine users "achieve" a modest but measurable increase in effective BA over time. That being said, in terms of raw analgesia, they're basically 1:1 assuming the patient achieves an oral BA of say ~27-33% or higher. I'm convinced that most of the people who always needed double the oral dose of morphine when compared to hydrocodone were ultimately inefficient metabolizers of morphine, and were only able to achieve an oral morph BA of like ~15-20% instead of ~30-40%.

Pill identification

View Thread Reply
- Thu, 21 Nov 2019 11:19:48 EST k3gioFlh No.612081
File: 1574353188945.jpg -(1929814B / 1.84MB, 3264x2448) Thumbnail displayed, click image for full size. Pill identification
Anyone know what this might be? It's got a capital M on the other side but this side in pic related is almost impossible to make out. It has a score line and it looks like it might also say 05 on on side of score line, which leads me to believe it might be Oxycodone. Not sure though.

4 posts and 2 images omitted. Click View Thread to read.
Edwin Blinderfet - Thu, 28 Nov 2019 21:17:43 EST A0ilEnUZ No.612251 Reply
cool i’m going to dph/sodium carbonate/citric acid/micron filter and cheese it
Cornelius Changerridge - Wed, 04 Dec 2019 00:40:35 EST A0ilEnUZ No.612336 Reply
wait is there a way to snort #3? like by converting it to #4
Emma Greenwell - Wed, 04 Dec 2019 19:03:06 EST 30kb9fBZ No.612368 Reply
you people and your silly heroin. black tar or bust

Is it to worth is to spend 85 bucks on a half g of fentadope?

View Thread Reply
- Tue, 26 Nov 2019 23:10:11 EST +YqNcs0a No.612198
File: 1574827811643.jpg -(199629B / 194.95KB, 1080x2220) Thumbnail displayed, click image for full size. Is it to worth is to spend 85 bucks on a half g of fentadope?
So the dope scene is just starting out in my area. And people have no clue had to handle it. One chick wants $30 a point all the way up. I must admit although all the tar ive botten in this southern state (not Texas) has been really decent. My main plug whos very well connected got some powder H which I'm assuming has fentanyl in it.

I should mention I have a realtivy higher tolerance than most people to fetty cause I used to cop in the city of brothery love's drug market.

I trust this guy although he doesnt use, (just served 5 years in prison). My main concern is it wont break through the 8mg of subs ive been taking for about a month now excluding today.

I know it will be on weight if not more I just really dont want to waste my money or die.

Any opinions?

(pic related, the brick my plug just picked up_
lol - Tue, 26 Nov 2019 23:21:41 EST IggaRoSW No.612199 Reply

You're still playing with fire regardless of your tolerance with shit that can be super strong. If you're just assuming and you got money to spend I'd suggest grabbing a rest kit, I get urgency is the name of the game with getting high especially when you've got the dope but you really can't be too careful these days. 30 a point is wild even for the most fire dope, at least where I'm from.
dr. m - Wed, 27 Nov 2019 14:52:16 EST LOk04uH3 No.612212 Reply
While I repeat this a lot on this board, whatever you do, just make sure you do VOLUMETRIC DOSING! Do NOT for any reason consume fentadope in dry form! If you consume it in liquid form and follow the common sense titration safety protocols, it's easily ~10-50x safer than consuming it in dry form.

Take the entire bag and weigh it minus the bag it came in. If you don't have a scale, you can buy one at a smoke shop for an overpriced amount (like $20-40), but personally I prefer buying from Amaz0n. I advise getting this one if you're on a low budget, as it's only $9.78:

American Weigh Scale AWS-100 Digital Pocket Scale, 100g X 0.01g Resolution

The next step up is a .001g scale (mg scale, cheaper one is a 10mg scale) and costs $27.78:

American Weigh Scales Gemini Series Precision Digital Milligram Scale, Silver 20G X 0.001G (GEMINI-20)

Then all you have to do is measure some water (go to a pharmacy and ask for an oral syringe for your dog's medicine, and if they don't just give you several different sizes for free, say the vet mentioned 10 milliliter oral syringe), pour the dope in a somewhat airtight container (search "dropper bottles" on Amaz0n and sort from cheapest to most expensive...I like the cobalt blue or amber colored ones), and then gently squirt the water ontop of the dope in the container.

Shake it like crazy for ~1.5-3 minutes, then let it sit for ~10-30+ minutes before shaking it up again. After you've shaken it once, waited ~10-30 minutes, shaken it a 2nd time, then waited ~15+ minutes, then shaken it up a third time, you can then either try a test dose or let it sit in the refrigerator. It's best to keep it in the fridge in case it's cut with anything that's sugar-based or otherwise contains calories, as bacteria can start to bloom like wildfire. Try to keep it out of the fridge for no longer than ~45-90 minutes while waiting for it to dissolve.

Then you should be ready to go. Make sure you write down the math. Treat it as if it's 2x as strong as pure carfentanil. Since carfent is supposedly 100x stronger than fent, and you can most likely handle 1mg of non-IV fent no problem, start with a dose of ~5ug (5 micrograms, aka 0.005mg). Wait ~20-30 minutes, and if you feel absolutely nothing, increase your dosage by 10x until you start to feel anything above placebo whatsoever.

Once you figure out how much liquid you need for a "dose," you won't have to slowly increase your dosage for the rest of the entire sack. You can snort the liquid, boof/plug it, possibly use it sublingually/buccally on your cheek/gums, or IV it with proper filters (0.22ug micron filters, which are also sold on Amaz0n).

Consider getting test strips from a place like dancesafe dot 0rg. They're $2 each shipped (you can buy just 1 if you want), and the reason I prefer these over potentially cheaper ones is because several studies have shown that not all fent test strips are created equal, particularly when it comes to fent analogues.

I agree with lol though...you're playing with fire. If you really want to lapse/relapse and/or switch between subs and dope/fent regularly, you're best off slowly tapering down to a less blocking sub dose, such as a maximum of 4mg, and even better something like ~3mg sublingual, ~2mg nasal/rectal, or ~1mg IV per day.
William Seblingwadging - Sun, 01 Dec 2019 14:34:23 EST Ft8bQzQh No.612297 Reply
Well if you want to break thru subs fent is the way to go. personally id rather be sober than on fent.

Fucking gay ass rules and shit

View Thread Reply
- Mon, 25 Nov 2019 14:46:29 EST 6DTNpgA+ No.612155
File: 1574711189672.jpg -(47533B / 46.42KB, 569x365) Thumbnail displayed, click image for full size. Fucking gay ass rules and shit
Anyways did anyone preorder from that one place? I did and my order hasn’t shipped out yet wanted to see if it was just me or what. I’ve sent a couple emails over the past month trying to get confirmation that it would ship out today and never once got a reply pretty fucking dumb. Sorry for making a thread it’s too bad there isn’t like a single thread I can drop this in as a post.
8 posts omitted. Click View Thread to read.
John Pockwell - Fri, 29 Nov 2019 12:46:26 EST 013riyBc No.612259 Reply
Oh yeah man somethings up. I already got my first order from a preorder back on Tuesday. Put another order in last night and it just shipped.
Dr. Katz !KqgSR25gAQ - Sat, 30 Nov 2019 06:43:37 EST Z4YJu/MJ No.612279 Reply
On the real, be fucking careful with disclosure of sensitive information—even if it is the brand of drugs. We do not wnat to make PST or any other semi-legal opioid more difficult to obtain as a result of negligent or careless posting.

God damn it, now I know what I have not fucked with PST in my life. Brand differentials, batch differentiation, and the overall size of packages if a major turnoff for me. But, I am quite fond of ingesting pharma grade morphine and among other opioids.

Doing heroin once

View Thread Reply
- Thu, 28 Nov 2019 12:40:17 EST GDnzJeg6 No.612245
File: 1574962817860.jpg -(52010B / 50.79KB, 680x680) Thumbnail displayed, click image for full size. Doing heroin once
My long time friend that unfortunately started abusing heroin and xanax a little while ago offered me a bundle of heroin. Im midly interesed in trying just once, is that even possible?
1 posts omitted. Click View Thread to read.
dr. m - Fri, 29 Nov 2019 14:12:34 EST LOk04uH3 No.612262 Reply
If you have no opioid tolerance, this is basically a suicide mission, especially if you don't consume it as a volumetrically dosed liquid. Most ecp #4 "heroin" in NA contains some amount of fentanyl analogues, and they're not all that evenly mixed.
Nell Bunridge - Fri, 29 Nov 2019 21:32:49 EST W7fR+003 No.612266 Reply
Make sure its good shit no fentdope, hopefully your friend isnt retarded and knows the difference. My long time friend who I would turn on to drugs like lsd then benzos then weed, i brought him an op80, after a few hours let him sniff some decent fentdope, he had a great time, really understood the whole opiate thing. Years later he hasnt touched any opiates. He also miraculously replaced a couple year benzo habit with weed, good for him.
op: i'd recommend getting some oxycodone or morphine pills, if you cant get guaranteed good dope. Personally I'd rather be sober than messing with fent, it has no euphoria and rapes your tolerance, it could be disappointing if youre expecting opiate euphoria.

TFW you get arrested for trafficking tea

View Thread Reply
- Mon, 25 Nov 2019 20:28:16 EST QZ8ZZ6+a No.612164
File: 1574731696574.jpg -(16508B / 16.12KB, 463x236) Thumbnail displayed, click image for full size. TFW you get arrested for trafficking tea
10 posts and 1 images omitted. Click View Thread to read.
Isabella Gavingfed - Tue, 26 Nov 2019 18:00:30 EST QZ8ZZ6+a No.612194 Reply
just contact the vendor and ask them. im sure they can give you a solid response
Cornelius Chiddlemad - Tue, 26 Nov 2019 21:51:03 EST x/MpvXPq No.612197 Reply
Kratoms legal in canada you fucking retards, that's LEGAL, as in not ILLEGAL.

I swear to fuck you fucking dummy fucks are fucked in the fucking head

Its kratom but backwards

View Thread Reply
- Tue, 26 Nov 2019 17:22:42 EST QZ8ZZ6+a No.612183
File: 1574806962519.jpg -(128444B / 125.43KB, 840x720) Thumbnail displayed, click image for full size. Its kratom but backwards
does anyone use Motark as a vender? just made my first non smoke shop purchase today. Im amazed at how cheap it is. 250 grams for 25$ is insanely cheap just wondering what the quality is like.


View Thread Reply
- Sat, 23 Nov 2019 13:51:55 EST JEykdT0v No.612122
File: 1574535115080.jpg -(44529B / 43.49KB, 640x480) Thumbnail displayed, click image for full size. Potinators
Long time since I've been here, just took five 10mg hydrocodone (narcos) for a experiment with my tolerance, normal five is a good high. But I wanted a bit more today. So I bought 100% grapefruit juice drank a big glass at least 20 oz, took a antihistamine (25mg vistaril, also broke the cap for fast acting). And lastly I chewed up the 5 narcos, and of course a bit more juice to swallow them. Will post in on how well these potinators and their combination works. For science.
12 posts omitted. Click View Thread to read.
dr. m - Tue, 26 Nov 2019 14:38:08 EST LOk04uH3 No.612175 Reply
Certain regional stores still sell 100% WGFJ (Publix still does, Food Lion did as recently as about 8 months ago, and Giant Eagle did as of about a year ago), but yeah, Walmart only sells what appears to be the 50/50 White/Ruby blend.

When it comes to WGFJ, it's always best to drink just a little bit, like ~150-200ml, once a day every day for ~3-5 days before you dose, and drink like ~350ml+ the day of dosing. I cbf to go track down the study I read that came to that conclusion, but it definitely was the conclusion of that one study. They basically said WGFJ messes with various meds by far the most when taken daily for up to a week before the medication.
Dr. Katz !KqgSR25gAQ - Tue, 26 Nov 2019 16:13:05 EST 9v++/pcV No.612179 Reply
Well I’ll be darned. I’ve heard of Publix, but yeah regional chains around me don’t have any WGFJ. The fact that regional chains have the juice is actually exciting. It’s been years since I’ve had WGFJ. Now, are these places producing their own in-store/generic brand or is it an actual juice company?
Quetzalcoatl !KDjYWIiOiM - Wed, 27 Nov 2019 21:40:38 EST OIpQoQ2U No.612215 Reply

hydroxyzine is one of the better potentiators for hydrocodone esp. among the first gen antihistamines

avoid wgfj

also lol @

>hydrocodone caps out at a certain amount but if oxy does not

you'll kill yourself with the APAP before you get close

What is available online besides kratom and seeds?

View Thread Reply
- Mon, 14 Oct 2019 16:29:44 EST oN6LT/Si No.611181
File: 1571084984839.jpg -(56348B / 55.03KB, 480x540) Thumbnail displayed, click image for full size. What is available online besides kratom and seeds?
I've had excruciating chronic pain after a car accident three years ago. My doctor has refused to give me a script for pain meds aside from a few weeks after a diskectomy(back surgery). He doesn't want me to be physically dependent, nevermind I'm on four other medicines that cause dependence. He just wants me to take 375mg aleve along with my other meds. It doesn't help that I'm 25.

Anyway kratom does pretty much jack shit. I know it isn't bunk I'll give friends 4gs and they'll be feeling good. Seeds are to expensive and such a crapshoot I can't rely on. I'd be interested in ODSMT but haven't found anywhere legit to order.

I would just do heroin like I have in the past but I can't drive, have no money, and everything has fentanyl now.

I appreciate any advice you guys have. Thank you
42 posts and 2 images omitted. Click View Thread to read.
Reuben Duckforth - Sat, 23 Nov 2019 18:48:49 EST 6DTNpgA+ No.612134 Reply
Were you talking about benzos by saying prescription pysch meds? You didn’t specifically say antidepressants or antipsychotica. Just pysch meds.

I was unsure what you meant by that. So I said “if benzos are what you’re talking about...”.
dr. m - Tue, 26 Nov 2019 14:54:37 EST LOk04uH3 No.612176 Reply
1574798077524.jpg -(776096B / 757.91KB, 1500x1016) Thumbnail displayed, click image for full size.
At some level there's got to be some gate keeping, and IMO daily benzos, "hard" stimulants (ritalin, adderall, etc.), and the like are just plain neither sober nor clean. In my mind, if it provides some sort of instant gratification-based subjective "high," then you're not "sober." Suboxone/subutex doesn't get me high at all (I wish it did). SSRIs don't get me high at all.

That's why I consider myself "sober" from full agonist opioids, but not clean. I've stopped taking adderall/dexedrine for almost a month now, and I haven't consumed cannabis in over 6 months. I've never consumed vyvanse, but I could see how low dose vyvanse could at least be considered as "sober" but not clean, as it takes forever to kick in and has basically no kick whatsoever.

Again, if I was getting these "sobriety" keychains for myself, then I'd probably not accept any simply because I (at least until recently) was taking daily dexedrine and drinking 2 glasses of wine once or twice a week. But at the same time, in my mind the only drugs I've ever had a serious multi-year problem with have been opioids, and to a much lesser extent benzos.

Regardless, there's about an 80% chance I'll be ordering some seeds in the next few days, probably 4lb, which I'll be giving half to my friend and keeping 2lb for myself to use either as one massive dose or two solid doses, depending on quality. I'll be leaving the country within ~50-60 days, so I won't even be able to get anymore seeds even if I wanted to. The most interesting thing will be whether or not I get cravings again after using, which will help decide if occasional use is even possible for me. I have over 1g codeine and 1g tramadol that's been sitting on my desk for month now, and I've had 0 interest in taking it.
Oliver Hundledock - Tue, 26 Nov 2019 16:03:01 EST qLlDx1SD No.612178 Reply
I wasnt saying theres anything wrong with psych meds. Just that they treat disease much like opiates or cocaine or whatever old drugs used to...by numbing the user. Only difference is that most psych drugs are not at all enjoyable like "older" drugs used for the same purpose. Benzos I guess are the most enjoyable psych drugs.
There are definitely people who need daily benzos but using drugs as bandages is just that, few dare to dive into the source of their problem. The belief that nearly all mental disorders, and physical disorders like fibro/ms/whatever occur almost out of nothing and have no cause and no cure is insane. Or its just "genetics." Lol.


View Thread Reply
- Tue, 19 Nov 2019 10:41:19 EST h6hF4z8+ No.612031
File: 1574178079525.png -(45358B / 44.29KB, 1200x1176) Thumbnail displayed, click image for full size. noko
Hey guys, my uncle passed away 2 years ago, i stumbled upon his medications stashed away in a drawer, i found a good amount of hydromorphone 6mg, and another bottle of 2mg. I live in Canada, what would be the average price of one of those? Also i dont know if anything i am asking of doing violates community guidelines, let me know and i'll remove my post thank you.
7 posts omitted. Click View Thread to read.
Augustus Chunningtad - Sat, 23 Nov 2019 08:21:34 EST CTiahFI1 No.612121 Reply
Good for you. Sounds like you have better habits than we do.
Oliver Hundledock - Mon, 25 Nov 2019 23:31:45 EST qLlDx1SD No.612169 Reply
Speak for yourself. Nothing wrong with some opiates.

actual opium

View Thread Reply
- Thu, 07 Nov 2019 13:05:26 EST YI42WDF3 No.611760
File: 1573149926322.png -(124905B / 121.98KB, 350x350) Thumbnail displayed, click image for full size. actual opium
aight so I've gotten hold of two grams of shireh (supposedly). i was planning to smoke it off of foil like heroin but the guy who sold it to me told not to do that, instead use direct contact with a hot metal rod...a bit like dabbing or hotknives I suppose. Does it make much of a difference? And how would I go about making it into a tea? Worth mentioning I used to smoke H but haven't for about a year now.
nod on boys
8 posts omitted. Click View Thread to read.
Frederick Snodridge - Mon, 25 Nov 2019 08:48:51 EST FmYsuyT/ No.612149 Reply
1574689731761.jpg -(40196B / 39.25KB, 347x567) Thumbnail displayed, click image for full size.
okay quick update.
Smoking is indeed a waste of time
Eating worked pretty well
Plugging has so far been unsuccessful. I tried just sticking a lump up me butt but it was really difficult (kept just smearing all over my finger which was really gross ), and I didn't feel anything much anyway. I just tried the dissolve and squirt method from >>611789, I'll update this if it works

thanks a lot guys
Ernest Wublingsedge - Mon, 25 Nov 2019 13:55:57 EST wBPrW/YB No.612151 Reply
Wtf you just shoved a lump up there? You need to warm it in water & citric acid or lemon juice n plug the dissolved opium in liquid

Just like no3 h
Doris Brookworth - Mon, 25 Nov 2019 18:59:15 EST qLlDx1SD No.612162 Reply
If you properly dissolve it and water enema yourself first, you will get a certified morphine rush from plugging O. Take heed, getting dependent on pluging morphine led to me shooting it cuz oral morphine wouldnt do it and I didnt like the plugging ritual. No regrets tho


View Thread Reply
!ZcijO7gk.6 - Mon, 11 Nov 2019 03:30:39 EST /tldDCDL No.611876
File: 1573461039798.jpg -(18966B / 18.52KB, 281x498) Thumbnail displayed, click image for full size. DEA, FBI, NSA OR ATF
Which agency do you suspect are lurking here. Quite a few of us have dropped off the face of the planet seemingly over the years. The internet never forgets and I suspect /opi/ has directly played a role in people that are likely doing bids right now...

Of course, there are those that have overdosed and faded into oblivion, but with opiates no longer an honorable problem, I feel like something is just off. The more I have thought about it, the worse it gets. Do you suspect /opi/ is "bugged"? Why wouldn't it be.

Inb4 I'm a stimmed out, braindead cunt. Be aware that if money from something seems good, it could cost you. We live in a weird time. If we don't adapt and stay observant, we are all as good as banned from IRL for at least 18 months a stretch.
32 posts and 1 images omitted. Click View Thread to read.
Ernest Wublingsedge - Mon, 25 Nov 2019 14:55:12 EST wBPrW/YB No.612156 Reply
Was funny when kft on dis accidentally posted his trip & it got used slyly when he was commenting to put fake posts from him up n it resulted in a few days of lols
Wesley Blagglestodge - Mon, 25 Nov 2019 15:14:22 EST QLXwWTGx No.612159 Reply
The whole WWW. was pretty much an experiment of the Military lol.
They don't need to lurk. they have a bot taking care of that and only sending specific patterns of interest to the feds.
Quetzalcoatl !KDjYWIiOiM - Wed, 27 Nov 2019 21:49:20 EST OIpQoQ2U No.612218 Reply
Sup Zombie?? Been a hot minute. Hope all's good with you besides the stims lol

prolly all of the relevant alphabet agencies keep some sort of monitor on the site (and all the chans tbh). Stuff like CP, drug sales, etc.

>The internet never forgets and I suspect /opi/ has directly played a role in people that are likely doing bids right now...

Ven got mashed for robbing a fuckin grocery store with a pellet handgun for like $57 or some shit, just to get a piece of a fent patch. Came on here, posted his whole fuckin' face and the pellet gun, with the story of how he just robbed them for a strip. So yeah it was all his dumbass fault. Prolly a few others that weren't such big news. A lotta people talk a lotta shit on here and post pics.

>Even people like Bombastus posting incredibly in-depth TEK's on how to convert codiene into hydromorph or hydromorph into Acetylmorphone probably isn't taken too seriously because who can validate the fact that it's true other than the person doing it themselves.

That and it's basically a matter of just paraphrasing existing patents that can be easily searched if you know what to ask google.

He was in mega junkie mode, and in Canada. Good luck getting a real handgun there, much less somebody willing to do time to hit a lick for a strip of fent. Woulda sold it before he used it to rob somebody.

Bump While Nodding: Tournament of Opiates vs. Opioids

View Thread Reply
!KqgSR25gAQ - Fri, 09 Aug 2019 20:04:09 EST 56TOD6Vq No.609151
File: 1565395449738.jpg -(80218B / 78.34KB, 1000x650) Thumbnail displayed, click image for full size. Bump While Nodding: Tournament of Opiates vs. Opioids
The previous BWN is no longer bumping. As such, here is the new BWN.
Post your opi of choice, binges, recreational usage, medically authorized use, and more surrounding this lovely class of drugs.

Today's current cocktail of Rx meds: 15mg diazepam, 50mg tramadol, 50mg tapentadol hcl (Nucynta), 15mg cyclobenzaprine, and 25mg DPH.
508 posts and 118 images omitted. Click View Thread to read.
Nell Crabberlock - Tue, 26 Nov 2019 17:28:28 EST uOLwkgo2 No.612184 Reply
That’s exactly how long I’ve been waiting as well man so I’m perfectly fucking chill for someone who can’t even get an email about when tf theyre going to see their 200 dollars of product
Nell Crabberlock - Tue, 26 Nov 2019 17:30:25 EST uOLwkgo2 No.612185 Reply

And I’ve been working for 2 months straight and am going home soon, the shits in stock but my order hasn’t been fulfilled so I’m wondering what the fuck is going on

Opioids from Yeast

View Thread Reply
- Tue, 19 Nov 2019 14:23:39 EST WvU6l7Ap No.612033
File: 1574191419742.jpg -(469912B / 458.90KB, 976x1280) Thumbnail displayed, click image for full size. Opioids from Yeast
>We combined enzyme discovery, enzyme engineering, and pathway and strain optimization to realize full opiate biosynthesis in yeast. The resulting opioid biosynthesis strains required expression of 21 (thebaine) and 23 (hydrocodone) enzyme activities from plants, mammals, bacteria, and yeast itself. This is a proof-of-principle, and major hurdles remain before optimization and scale up could be achieved.
The opioid crisis is about to get a lot worse and the potential here is limitless. Psilocybin, THC, cocaine, you fucking name it can all be made with this technology. Genetically modified yeast are going to be the Nagasaki and Hiroshima of the war on drugs.
3 posts omitted. Click View Thread to read.
Edwin Gollyfeck - Wed, 20 Nov 2019 21:43:18 EST 3LIh5bI/ No.612069 Reply
Some rogue scientist could become filthy rich.
Dextrolord - Thu, 21 Nov 2019 03:27:32 EST t9+obISS No.612075 Reply
screw you my higher level chem education hasn't even started yet

Report Post
Please be descriptive with report notes,
this helps staff resolve issues quicker.