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Discord #Drugs Channel Now Open

Sensory Enhancement After Withdrawal...

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- Thu, 29 Aug 2019 20:17:03 EST 4tsYqeia No.609906
File: 1567124223268.jpg -(13232B / 12.92KB, 246x279) Thumbnail displayed, click image for full size. Sensory Enhancement After Withdrawal...
Anyone notice sensory enhancement when they quit opioids? WD ended on monday and since tuesday ive noticed visual/auditory enhancement. For some reason these sensory enhancements have dulled since I just ate some fast food an hour ago. I noticed literally in the restaurant as I was eating my heightened senses just dulled. Wtf?
4 posts omitted. Click View Thread to read.
Wesley Dartwell - Thu, 12 Sep 2019 00:08:05 EST 9THM2EjY No.610266 Reply
Yes op it is very true. Sounds and Smells especially became overbearing and drive the senses mad. I just got outta jail today and the whole week I was in there I was wding from bupe. Every time food was brought into my cell I'd vomit from the smell alone. (Granted, jail food is horrid anyways, but still)

>>609908 essentially my same thing. Food I'd normally find delicious completely sober or high on opi becomes so.repulsive in wds that the smell alone causes vomiting and uncontrollable/unwarranted thoughts.
I find sleeping to be a weird experience too. I dont seem to sleep or "dream" really. It seems like I lay there at night and a certain train of thought or some absurd idea forms and just repeat it in slightly different t ways over and over until I begin to ache from lying down too long. I get out of bed with bags under my eyes feeling like I didnt get a second of sleep and only further exhausted my body/mind even more. Today soon as I got out of jail my sister hooked me up with 100mg hydrocodone. Immediately the stomache aches and smell sensitivity vanished and I could eat and drink with no issue. You're definitely not alone on this one bub
Thants !IZgeXR9w82 - Sat, 14 Sep 2019 13:39:47 EST OgX3IMCX No.610365 Reply
Very true. My whole body comes alive with the strangest physical sensations, huge spikes in mood and attitude, moments of extreme empathy, brutal guilt and sadness, deep logical thought and sheer desperate stupidity/suicidal ideation (even though generally I pass through these states quite rapidly and have never been much for intentionally hurting myself). If we could take away the agony of WD I think there would be a lot of room for intrapersonal growth there.

Getting off H with Kratom taper?

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- Wed, 11 Sep 2019 09:36:51 EST NjmKkIbD No.610224
File: 1568209011578.jpg -(28695B / 28.02KB, 680x361) Thumbnail displayed, click image for full size. Getting off H with Kratom taper?
Hey guys, so I've been smoking about 0.1 g of BTH twice a day for the past month or two and I need to stop. I've got 500 grams of Kratom headed my way w/ 125 grams each of Red Bentuangie, Red Hulk, Starburst and Green Hulk, and I'm taking 6 days off from work next week to just hammer this shit out. How would you guys recommend doing the switch from H to Kratom and the taper down? I've only done Kratom a couple times in the post and never really felt much from it (I'm guessing low potency combined with high opi tolerance).

So far someone I know recommended taking 5 grams of Kratom every 3 hours or as needed... so do this for the first 24 hours until I feel okay, and then just taper down with 4 grams every 3 hours the next day, 3 g/3 hr the next, 2 g/3 hr the next, and finally 1 g/3 hr the last couple days?
11 posts omitted. Click View Thread to read.
Edwin Murdham - Fri, 13 Sep 2019 21:42:23 EST NjmKkIbD No.610345 Reply
>it's up to you to decide how quickly you want to taper, whether to drop a little per dose or per day, or even per week if you're really having trouble with it. personally I prefer a slow, mostly painless taper since it's easier for me to stick with it and resist relapse/redosing if I'm not miserable but it sounds like you want to be done with this quick

Well, avoiding discomfort is definitely also a priority (lol). My reason behind wanting to get this over and done during the six days I have off is that it sounds like I'll probably be having to dose on Kratom about once every three hours for the duration of the taper, and that's not really a possibility at my job. My work day is about 8 to 10 hours and it'd look pretty sketch to be consuming some random powder every three hours--not sure I want to risk anyone asking questions.

Or is a long, relatively painless taper still doable even if I'm only dosing once in the morning and once at night? I know the duration of Kratom's effect is longer than H but it's not up to the level of methadone, right?
Kekistan69 - Fri, 13 Sep 2019 22:20:51 EST JEt2x1Cb No.610346 Reply
Kratom does not last very long. I'm a daily user (def addicted but I don't really care, it's not really negatively affecting my life and health like real opiates were) and I have to take it every 2-4 hours to maintain a buzz throughout the day. I feel that the effects seem to last shorter when going through any type of strong opioid withdrawal. So if you want to avoid discomfort take 2-4g every 2-3 hours. It really isn't dangerous and there's no risk of overdose so even taking 20+ g a day isn't gonna hurt you. I would recommend taking it every 2-3 hours like I said, there's no reason to suffer through withdrawals when there's a relatively harmless plant that can dampen the wds.
Priscilla Clayford - Sun, 15 Sep 2019 00:10:38 EST cbXJ46oj No.610374 Reply
Just take it when you need it and an hour before going to sleep. How long it's effective depends on so many factors (personal biology, length and severity of addiction, ect.) that it only really makes sense to do it based on when your withdrawals start to come back.

For example, the most recent time I switched off to kratom I was able to go ~6 hours comfortably (relatively) between doses, and at a lower dose than most people were suggesting (way lower than the last time I tried kratom, where it was basically ineffective even at 6+ gs). I was initially dosing every 3 hours and wasting tons of kratom, not to mention pointlessly extending my taper and increasing my tolerance. Not that I'm saying it will be the same for you, but you should see for yourself how long you can last and how low of a dose keeps you well because if you just go with what some strangers online say, you can easily end up just treading water so to speak.

As far as dosing at work, buy 1000 capsules off amazon, put on a TV show and spend an hour filling up like a weeks worth. You can just press the capsule into the powder. then you can just go to the bathroom when you need to dose. A single 00 cap fits about .5g when fully filled, making it super easy to dose (although if you have a good scale, you should weigh out your first few capsules to get a more accurate average). and by the time you go back to work you should have a good idea of how long you can wait between redoses and how much you need to take anyways so I don't think it'll be an issue.

just ordered online... am i btfo?

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- Thu, 12 Sep 2019 20:22:16 EST 8F4IFIQ8 No.610303
File: 1568334136480.png -(406075B / 396.56KB, 600x449) Thumbnail displayed, click image for full size. just ordered online... am i btfo?
i have a prescription from my doctor that took me a long time to get back... (hydrocodone) and then stupidly i took them too quickly and ran out and the 1 ii saved might not be enough to pass my test... so i thought ill look online and i just completed a wu transfer to pay from a website (i wont say here i read its against the rules) im just curious if anyone else has done anything like this? im not a drug user im just someone in alot of pain and i misused.. my first week they didnt work well i think because lingering buprenorphine blocking it (was on all forms of that thru this year it didnt work well for me), and then they started working better and then my cat died and i just wanted to sleep and so i took too many... if that hadnt happened i would have been able to make the 20 i set aside last without issue, i shouldnt need more than 3 per day as long as they work right

anyways thats my story i have severe painful ulcerative colitis and a spinal deformity kyphosis

am i probably scammed or fucked? is it likely fbi is included with overnight delivery orders for a first time buyer? it was some indian sounding guy in florida, my guess is its a doctor or pharmacist selling on the side - definitely very illegal :(

ill never do this again i just hope they are real and dont kill me with fentanyl im not a drug user so my tolorance isnt huge, in my 2 month hospital stay last year i was on 2mg dilauded and then 7mg morphine (dilauded shortage) 4x or so per day, and sent home with oxy and ms contin, doctor made me switch to trying buprenorphine in april and it didnt work until the sublingual form subutex but that gave me lots of side effects even at just 3 2mg/day and no diarhea help

anyways i hope this works out and saves me... i gave my self birthday present money up to do this
8 posts omitted. Click View Thread to read.
Nicholas Geckleforth - Fri, 13 Sep 2019 01:00:59 EST mtvrtOdO No.610322 Reply
I wish I could tell you where OLPM's that are not rip offs can be found easily.

Don't worry, customs don't go after you unless you tried to import in massive amounts of something, but they will look at your international mail more often, they kind of figured out that regular air mail has to be watched as much as registered, tracked etc. Took me a one year 1/2 of only ordering CD's, vinyl records and random shit only, which on discogs often mean international orders, to get a sheet of clonazolam blotters again. When they figure out blotters, it's because they're watching the sender, who in my case did sell things illegal in Canada like many 2c-x products....they used to be staple RC's since like year 2000 with the oldest RC stores in canada always having them, but fucking NBOMEs and the people laying it like it was acid caused a hell lot of phenethylamines to get banned up here almost at the same time they legalized weed, so customs people who do not have to look for hash from elsewhere or weed from say canada to netherlands or vice-verca, they're bored and are getting overzealous, Canada's largest import, even more than oil is weed, billions and billions made in profit by mostly independent groups, not bikers and shit like in the past, since the markup to to the eastern part of the US is so extreme, a 120oz bulk dank will be 350 in Upstate NY...
Matilda Diffingkot - Fri, 13 Sep 2019 09:45:43 EST 7OW1/2F8 No.610329 Reply
You can absolutely find clear net online pharmacies that'll ship you generic pills from india. Can't give you any sources but they do exist. The only opiate the one I use sells is tapentadol, but that could help your pajn. Apparently the poppy seeds going around now are shit, but your best bet is still probably to make some pst because seeds don't have to go through customs and you'll have em in a matter of days. Do your research on it, because most seeds these days are apparently garbage.
Esther Chizzlefatch - Fri, 13 Sep 2019 12:11:26 EST 8F4IFIQ8 No.610332 Reply
thanks for the replies, ive had some sense and decided to cancel my order - i was also able to cancel the payment and should receive a refund soon, they said they already sent package and "tracking coming soon" but im pretty certain at this point its just a dumb scam and i was stupid to ignore obvious signs of it all the way

i dont think ill hear from them again

desperation breeds stupidity

i just hope i can pass my test

How to pass a methadone clinic drug test help

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- Sun, 08 Sep 2019 20:00:00 EST osznr6gK No.610144
File: 1567987200525.jpg -(34882B / 34.06KB, 637x578) Thumbnail displayed, click image for full size. How to pass a methadone clinic drug test help
I get random monthly drug tests at my methadone clinic in the USA, and I saw a reply on a previous post from a user named "Hillbilly Heroin" saying to freeze my "clean pee"(pee only containing methadone) and reusing it for future drug tests. Can anyone elaborate further on this method? Preferably the above named user or someone else with first hand experience. How should I reheat the frozen pee? Soaking in warm water, microwave? Once it's at the right temperature will hand warmers keep it warm enough until test time? Can the pee be frozen/reheated/frozen repeatedly and still work? Like I said my tests are random so I'd have to come prepared daily with warm pee, and I'd rather not have tons of pee in my freezer if refreezing/reheating multiple times is possible.
5 posts omitted. Click View Thread to read.
Junkie McGee - Thu, 12 Sep 2019 01:25:10 EST osznr6gK No.610271 Reply
Whenever you get a chance I'd still like to know your method
Priscilla Clayford - Sun, 15 Sep 2019 00:16:35 EST cbXJ46oj No.610376 Reply
he probably just uses his office microwave to reheat it like the rest of us.


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- Wed, 11 Sep 2019 04:00:20 EST tzRROuin No.610210
File: 1568188820797.png -(128311B / 125.30KB, 600x297) Thumbnail displayed, click image for full size. suboxone
Does mixing a suboxone strip with vape juice and putting it in your vape remove the nalaxone?

How do people remove the nalaxone?

i've been taking suboxone for 10 years sublingually (around 2mg a day, sometimes more) i want to know more shit about this miracle drug that allows people to live healthy normal lives. any tips?
9 posts and 1 images omitted. Click View Thread to read.
Martin Worthingson - Wed, 11 Sep 2019 21:02:37 EST cbXJ46oj No.610258 Reply
ok a bunch of posts showed up, I didn't refresh the thread before replying and I'm not going to read them now. so apologies if all of this has been said and further apologies if everything I said was wrong idk I wish I could delete posts sometimes
Wesley Dartwell - Thu, 12 Sep 2019 00:13:23 EST 9THM2EjY No.610267 Reply
I've noticed it too. Not just with the onslaught of retarded suboxone related posts and threads, it seems like its forced. Unless all the newfags who come here magically all have similarly noobish questions on the same topic. Who ever the unwanted guests are, dea FBI etc, it feels unnatural and is noticable to those who post here or browse here frequently.
Martin Worthingson - Thu, 12 Sep 2019 08:36:45 EST cbXJ46oj No.610279 Reply
classic DEA, infiltrating our board to get... suboxone advice? alternative take, this place has always had its share of idiots and noob questions and it doesn't seem like it'll be slowing down anytime soon. lol you guys say this shit all the time about everything. although I'm gonna feel pretty dumb if this ends up in a court transcript.


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- Tue, 10 Sep 2019 03:08:57 EST l5B+ZWAB No.610172
File: 1568099337241.jpg -(21608B / 21.10KB, 640x366) Thumbnail displayed, click image for full size. Cymbalta
So, I have a rare medical condition and I have a pain support doctor and she prescribed me Cymbalta for neuropathy. She told me my other alternatives was gabapentin or lyrica. Both seem to be worse then Cymbalta but I'm worried about withdrawals. Any suggestions?
5 posts omitted. Click View Thread to read.
George Socklebanks - Wed, 11 Sep 2019 02:10:33 EST 7OW1/2F8 No.610207 Reply
>Cymbalta for nerve pain
That shits pure poison. Lyrica is better and you can actually get high on the shit. There's no reason to be prescribing snris for neuropathy. Lyrica will actually help you and won't fry the fuck out of your brain.
Dr. Katz !KqgSR25gAQ - Wed, 11 Sep 2019 02:39:43 EST 56TOD6Vq No.610208 Reply
All this.
Gabapentin/pregabalin > Cymbalta
HOLY SHIT! If given the choice I would pick gabapentin or pregabalin 10/10 times. Dead serious. Cymbalta has its place in medicine, but I do not want that drug in my bloodstream.
Phyllis Bobblewell - Wed, 11 Sep 2019 05:11:56 EST mtvrtOdO No.610215 Reply
I'm not saying I believe it. But it's in the monograph's main uses other than depression, not even an off-label bullshit thing like trazodone for sleep.

oxy lol

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- Fri, 06 Sep 2019 08:43:19 EST +ZzeMt2f No.610092
File: 1567773799802.jpg -(99323B / 97.00KB, 848x1200) Thumbnail displayed, click image for full size. oxy lol
so I used to get a lot of oxys n recently a few more have come my way..proper non gelling ones
personally I remember this to be most efficient
have ur shit
inabit plug 40mg acetyl l carnitine
then crush the decoated pill in a mortar n pestle in cordial or water whatever you have on hand
crush into a fully solved solve'
add a pinch of bicarb of soda for water and a larger pinch for cordial
let it react if you mixed with juice or ALC'
suck dat shit up in a circular motion to stir and suck at the same time
plug this 20 min after the ALC
Lie down for a minute with your torso slightly raised
now is the time to do sublingual benzos if you do
3 posts omitted. Click View Thread to read.
Graham Henkinlutch - Tue, 10 Sep 2019 16:44:20 EST N5y4CAMK No.610191 Reply

MY solution comes out very homogenous not particulate riddled
and their proper UK ones

does it really help filtering to a liquid not a smoothe solution?

plz explain properly for me to confirm
Graham Henkinlutch - Tue, 10 Sep 2019 16:47:41 EST N5y4CAMK No.610192 Reply
you would of loved seeing the stuff which used to go on in these hallowed, recently centralised threads on /opi/, /dis/ & even /weed/ when that was on about mids scales, eye my dime and can i weed butter wrong anyway threads

Graham Henkinlutch - Tue, 10 Sep 2019 16:48:30 EST N5y4CAMK No.610193 Reply
you would of loved seeing the stuff which used to go on in these hallowed, recently centralised threads on /opi/, /dis/ & even /weed/ when that was on about mids scales, eye my dime and can i weed butter wrong anyway threads


New to heroin, not new to opiates.

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- Sat, 10 Aug 2019 20:44:57 EST 3R2Nm3/L No.609242
File: 1565484297170.jpg -(84276B / 82.30KB, 500x650) Thumbnail displayed, click image for full size. New to heroin, not new to opiates.
Hey OPI, so I'm curious on what dosages & prices I should be looking for when trying heroin for my first time.

Some background:

I'm in North America, Canada specifically.. - I say that for an idea on the price range for, let's say... a gram.

I've done plenty of opiates, have had multiple bottles with 100 pills of oxy 5mg & 37.5mg tramadols I'd pop up to 35mg & 500mg of a time of (oxy being over 2-3 hours, tramadols being over 5-6 hours), hydrocodone 5mgs that I would snort tons of, can't recall the amounts honestly..
So I'm not heavily into a tolerance when I have done them, & am currently with little to no tolerance..

I'm planning on snorting, & will be doing research on swallowing whether or not that's even a thing.

I've read anywhere from 150-200 is the price for a gram, but I want to be sure what an alright price is. & for dosing, I have no idea what I should be trying out - assuming there is no fet. I'm not too worried about fet, but I want to start on the lowerside to be cautious. I don't want suggestions on buying test kits etc.

Thanks for any help yall can provide.
28 posts and 3 images omitted. Click View Thread to read.
Rebecca Wubblebodging - Sat, 07 Sep 2019 06:14:23 EST mtvrtOdO No.610118 Reply
Not true in Vancouver, that's dope city in Canada since a long time, all ORT patients prescribed pharma heroin ampoules because they have unacceptable side effects from methadone and suboxone live in Vanc, all 30 of 'em, heh. Southern Ontario peninsula has it, although since it's kind of in the middle of the US, with many states more north from it, Fenthoine is common there. There's some in Montreal too, but it's kind of an upper scale drug weirdly enough, there's some in east st-catherine street, the bad french speaking area, but most are like Cocaine dealers, you don't even see them, they got their delivery guys and it's all very professional. Only time I saw some, it was #3 brown and my friends smoked it, I was already sideways from oxy and hycodans at once so I passed.

And indeed, loads of MDMA/meth pills are made here, the bikers and shit have the decency of making the white pills mostly meth and the nice colourful presses MDMA/MDA/MDE and if there's meth in it, there's just a litttle so that the comedown 5 hours later doesn't make you crash hard, like it can happen sometimes as we all know, I guess.
DrFeelsGoodMan !psUx8WBMWI - Sun, 08 Sep 2019 02:51:34 EST ZYHpFVwP No.610131 Reply
I'd shit bricks if I had to pay over 100 for a gram of dog. Usually 80ish in the D. Always start small, tiny bumps til you can see if its cut harshly. Then keep rebumping every 30-60 mins, keeping an eye on where you are high-wise. Always have someone around, never do it alone, someone has to be able to call an ambulance. be safe, use safe, dont die mang. tiny bumps will usually get you a rough idea of tolly, and keep you alive.
Angus Clommerstone - Tue, 10 Sep 2019 10:41:03 EST mtvrtOdO No.610184 Reply
Thanks man, but I'm covered for my pain issue that led me to use recreationally, finally, I had to go through the needles too, but it was high dose hydromorph. Now I'm scripted generic oxycontin 60's - Oxycodone-CR every 12 hours and i'm good, I catch a good nod here and there still, I just call em naps when seeing the pain doc every month so as not to raise suspicion. I guess 40's would be enough for the pain, but I pushed for a little more, knowing I wouldn't get 80's, but 60's enough, and yes I can chew em, I usually chew half. Been doing this since a year now and no silly ideas of taking way more after the whole ORT almost-decade long BS I went through.

Synthetic Urine for Drug Test Help

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- Mon, 02 Sep 2019 16:24:04 EST osznr6gK No.610000
File: 1567455844615.jpg -(86202B / 84.18KB, 1388x1179) Thumbnail displayed, click image for full size. Synthetic Urine for Drug Test Help
Has anyone used synthetic urine for a drug test? Did you pass or were you caught? I'm on methadone and have been using again (fuck me right) for the past 3 weeks and have a random test sometime this month. I'm desperate and considering buying the synthetic urine they have at my local smoke shop. The tests are not monitored and I'm not even sure there is a temperature test on it, I piss in a cup and bring it back to the front desk and it gets shipped somewhere else for testing. Anyone have experience with this? Or any other methods for passing a urine test? I was gonna pour a tiny bit of methadone into the fake urine and hope it works.
10 posts and 1 images omitted. Click View Thread to read.
lol - Sun, 08 Sep 2019 03:32:53 EST oaWRMjn3 No.610135 Reply
All you need are a pack of handwarmers, nothing fancy, saved us much jail time, this is for probation though, if you arent monitored you should just be able to find someone with the piss you need in time.
Cedric Goodshaw - Sun, 08 Sep 2019 04:15:06 EST UcO7GTMq No.610136 Reply
Right yeah, I figure that clean piss from a friend would be best, although I don't have many irl friends who would eithet help, or who can't piss clean ( due to having their mmj card ), hence why I was curious about the synthetic urine ( quick fix, or testclear ).

Wondering if urine can be shipped, mailed? obviously it would be frozen, sent in a jar, in a lunchbox or something of the sort, and sent with 1-2 day shipping, but, will this work? is this possible?

anyways, I appreciate the responses and insights

Norco shooting

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- Fri, 06 Sep 2019 18:09:34 EST pNXu5nBX No.610105
File: 1567807774520.jpg -(14364B / 14.03KB, 480x360) Thumbnail displayed, click image for full size. Norco shooting
Is it safe to shoot up norcos? Asking for a friend like what's the process?
Rebecca Wubblebodging - Fri, 06 Sep 2019 20:44:28 EST mtvrtOdO No.610107 Reply
NO. Hydrocodone is not safe to shoot, that's probably why ZoHydro got the bad press it got, people with 70mg ZoHydros thinking they got tons of shots in those capsules.

Also, Norcos have tylenol, you don't shoot up tylenol either. 18 year old senor detected.
Henry Nangersat - Sat, 07 Sep 2019 02:37:43 EST cbXJ46oj No.610115 Reply
the process is you don't do it. I know rebecca already said that but some of you dumb fucks don't listen so it needs to be said again: DON'T SHOOT HYDRO.
and especially don't shoot fucking norcos, fucking christ. might as well shoot some tylenol 3s while you're at it. you've got to be a highschooler cause I have a hard time believing you could live past 20 with those kinds of ideas.

Favorite daily opi?

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- Sun, 01 Sep 2019 00:16:02 EST DOtmUPy9 No.609951
File: 1567311362677.jpg -(135265B / 132.09KB, 1371x1300) Thumbnail displayed, click image for full size. Favorite daily opi?
There's lots of threads about peoples favorite opiates period, but there's a big difference between one off use and daily use. What's your favorite daily opiate to use daily, that has the most euphoria over the long term and least downsides.
7 posts omitted. Click View Thread to read.
Graham Mogglewill - Wed, 04 Sep 2019 00:26:28 EST mtvrtOdO No.610051 Reply

If you're Canadian, your Talwin is untainted by Naloxone. We got Suboxone really late here because it had to skirt our law that adding Naloxone to pentazocine tablets because one knows people crush the tablets and it will hurt them if they abuse them through IV is an illegal thing here. It's called only Talwin up here, while in the US it's Talwin NX. Do not shoot up Talwin NX.
Rebecca Brublingnudging - Fri, 06 Sep 2019 07:32:44 EST mtvrtOdO No.610091 Reply
I almost bought tiny green pills of that stuff, it was some of the best most easy to manage fent analogue out there, like, no need to even inject. Fu-F nasal spray is the strongest thing I guess I ever got on RC sites. Fent analogues having completely disappeared from the places I know of, which is kind of a good thing, H has got to be H again.

But I'm still made I didn't buy those microdot sized green pills of 4-FIBF, I was a hair trigger with my mouse about to click to pay with crypto for 1000 pills of the stuff, wisdom prevailed, also I could get 8mg dillies for a ridiculous price back then.
Samuel Clusslefield - Fri, 06 Sep 2019 13:43:59 EST MyhMIj19 No.610100 Reply
  1. Buprenorphine - lasts for ages, cheap as hell, gives very meh kind of high, but apparently still works, keeps me happy and wd-free all day long, sometimes I'm able to catch a light nod when smoking a cig
  2. PST - even though it's been over a year since I had some decent seeds, I still have fond memories of it, cheaper than morphine, doesn't require shooting, lasts long and gives all around good opi high
  3. Oxycodone - a bit pricey when used daily but damn it's great, multiple ROAs, euphoric and stimulating buzz great for work and when I'm at the uni, only downside is it gets me physically addicted really fast and my tolerance grows like crazy

Suboxone and Coke IV

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- Fri, 06 Sep 2019 01:21:00 EST +YqNcs0a No.610087
File: 1567747260985.jpg -(108311B / 105.77KB, 700x700) Thumbnail displayed, click image for full size. Suboxone and Coke IV
just did a shot of like .5mg suboxone and .05mg coke

Rebecca Brublingnudging - Fri, 06 Sep 2019 07:03:56 EST mtvrtOdO No.610089 Reply
>IV'ing suboxone

Hopefully they're not the pills, because they're full of lime and lemon natural and artificial flavours, they're known to give cavities if used long term, like I did, had perfect teeth, 2 tiny cavities when I was in my late 20's and now all of em had some work done on them, it's a miracle, but my insurance only pays for white filling for front teeth, canines, and upper pre-molars, so I got a mouth full of nasty composite black fillings now...did a perfect job and was transfered to a pain clinic where i'm getting Oxycodone-CR 60's every 12 hours now.

Point is, shooting up suboxone pills hurts you because of the lime-lemon / high ph in the pill powder, the flavours get into the water and I know 2 people who fucked their insides in 2 different ways doing that.

If you got em from strips, seems interesting. Although I always preferred to turn my coke into freebase if I was going hardcore, IV coke always freaked me out re: my heart. Hopefully it was fine, although a better opiate would be way better, almost anything else that can be IV'd in the opioids heh.

Armchair pharmacokinetics

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- Tue, 03 Sep 2019 05:18:06 EST zaurUfK0 No.610024
File: 1567502286870.jpg -(78797B / 76.95KB, 547x600) Thumbnail displayed, click image for full size. Armchair pharmacokinetics
So I'm bored and high/drunk and thought I'd solicit some ideas. I'm a weekly chipper who prefers poppy seed tea, primarily a mix of morphine and codeine. I'm trying to increase the duration of my experience without necessarily increasing the peak plasma concentrations. I.e. I'm not necessarily looking to improve first pass metabolization (Although I plan to cover the standard cyp enzymes for that). My aim is to slow down the 2nd pass metabolization by UTG enzymes. After a bit of reading I'm pretty certain that UTG2B7 is the specific one I want to inhibit. 1A1 is also involved to an extent but everyting points to 2B7 as being the main culprit for morphine glucuronidation (M3G, M6G).

The only viable OTC inhibitor of 2B7 I have found is an antifungal called Ketoconazole. It has the nice property of becoming concentrated in the liver after administration (Takeda et al. 2006) but unfortunately its mostly in topical applications (except for a fish tablet I found lol). I haven't found any herbal sources although I am investigating a few leads.

So besides any UTG inhibitors (and I would love to know about any), has anyone come up with a reliable way to inhibit second-pass metabolization of morphine to its removal products (besides its demethylation which is P450 related)?

And yeah I realize morphine will still be removed despite inhibition of both CYP and UTG enzymes but any help is fine.
Ian Shittingworth - Tue, 03 Sep 2019 10:24:37 EST cbXJ46oj No.610029 Reply
well in the spirit of the thread title I'm going to be talking out of my ass quite a bit here.
ok, I haven't looked into inhibiting UTG but I feel like that is something of a dead end. If something that was easily accessible and safe could increase morphine duration for "free", it would probably have been found already. There's a chance something slipped through the cracks, but you'd be on the cutting edge of that specific use so no telling about any health effects.

My thought would be to find out why PST lasts so much longer than plain morphine (my guess: all the other alkaloids clog up the works, or it contains a specific compound that increases the duration through some mechanism).
If it's the former, buy some cheap, mildly active (but not bunk) seeds and use those in conjunction with the good ones (experiment; I'd do a few tests doing them simultaneously, dosing the cheap stuff 3 hours in, dosing it 6 hours in, and dosing it 2 hours before, just to get an idea on what effect, if any, it has).
If it's the latter, that method might also work. Of course, if someone got the funding and used meticulous, well documented trials to compare the resulting effects with chemical analysis of the seeds we could actually get somewhere but of course that will never happen.

I will end on the easiest, simplest, possibly only answer: redose.
dr. m - Wed, 04 Sep 2019 08:17:13 EST LOk04uH3 No.610056 Reply

Yeah this guy is dead on about combining with other seeds. Find a solid Spanish seed vendor that charges no more than $4/lb, preferably ~$2-2.50/lb. They exist. Then do a first wash ONLY on these seeds, no second wash. Then reuse that first wash as your liquid for doing a first wash on your regular UK seeds. Then use additional water on the side for your regular second wash.

The other alkaloids, even the non-opioid opiates, indeed clog up the works so to speak.

HELP! Taking my prescribed suboxone while on heroin to make my pupils dilate/normal

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- Tue, 03 Sep 2019 13:40:27 EST TMMZRLPd No.610032
File: 1567532427846.jpg -(77939B / 76.11KB, 710x533) Thumbnail displayed, click image for full size. HELP! Taking my prescribed suboxone while on heroin to make my pupils dilate/normal
My mother can always tell 110% of the time when I'm on any substance. I will see her in a few hours and my pupils are small from opiate, specifically heroin, usage. I am prescribed Suboxone, since Suboxone will cause me to go into withdrawal and I was wondering if that would make my pupils normal? Withdrawing on opiates anyway causes ones pupils to dilate. Will this work? Also any other ideas for making my pupils dilate? Thanks for the help!
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My mom can always tell by my pupils - Tue, 03 Sep 2019 20:05:38 EST TMMZRLPd No.610046 Reply
I rarely take heroin anymore, I take subs everyday. I took dope for 2 days str8 basically, and took the subs. I had minor withdrawal for an hour or so but felt normal after. Granted, if I was deep in heroin, I would never force withdrawals on myself by taking Suboxone, that would feel terrible. It worked in this case since I had always been taking subs so the withdrawal was nonexistent. She knows about the subs as they are prescribed, btw guys everything worked out she didn't know I took anything this morning and the crisis has been averted lmao. Thanks for the suggestions though
Cedric Billyham - Tue, 03 Sep 2019 21:22:40 EST DOtmUPy9 No.610049 Reply
That's really good to hear, I thought you were actually high. Glad to hear everything worked out.

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