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420chan is Getting Overhauled - Changelog/Bug Report/Request Thread (Updated July 10)
Hydrocodone Ignore Report Reply
Graham Fandleridge - Fri, 12 Jul 2019 18:09:10 EST fWGcvW62 No.608038
File: 1562969350964.jpg -(106679B / 104.18KB, 483x643) Thumbnail displayed, click image for full size. 106679
How difficult is it to od on hydros?
dr. m - Fri, 12 Jul 2019 18:46:26 EST 1qKXc0ke No.608040 Ignore Report Reply

It mostly depends if they're real or fakes pressed with fentanyl analogues. I have received fake vicodins in my life not joking, but they happened to be completely bunk and after closer inspection it wasn't the best fake I've ever seen.

If they're real and it's you're first time ever with an opioid, take 15-20mg to start for a decent buzz. You may need more but some people will puke from even just 20mg.
Sophie Trotforth - Fri, 12 Jul 2019 19:39:48 EST 7Teze97q No.608043 Ignore Report Reply
Awesome, thanks. These are an old script of mine, so I don’t have any concerns about faking.

I’ve got 30mg total, and I’ve used them a bit in the past, but not a ton. If I just do all 30 will I die horrifically? Split into two 15mg nights? I’d rather have one great dose, but also want to keep breathing.
dr. m - Fri, 12 Jul 2019 22:31:43 EST 1qKXc0ke No.608046 Ignore Report Reply

Nah 30mg can't kill you if you're a adult male over say 140-150lb unless you have a double positive allele for that enzyme (makes it more effective). Even then, nah 30mg hydrocodone can't kill you. 30mg hydrocodone roughly equals 20mg oral oxycodone, and the highest therapeutic dose they prescribe for zero tolerance first time is 10mg every 4-6hr. So twice that amount can't kill you.

Either take the entire 30mg all at once period, or take 15mg all at once and wait 7-10 days minimum to take the other 15mg all at once. Waiting 14 days is optimal for tolerance and to prevent mental addiction creeping up over your lifetime.
dr. m - Fri, 12 Jul 2019 22:33:03 EST 1qKXc0ke No.608047 Ignore Report Reply

That's assuming you don't drink, dont take benzodiazepines, any other weird downers, and aren't on a million different medications that might react.
Hugh Grandwater - Fri, 12 Jul 2019 23:10:49 EST bccFwTjF No.608048 Ignore Report Reply

are there any serious interactions with any pharm opiate (hydro, oxy mostly) and bi polar medications (lithium, risperdone, and congentin)?

I'm aware of the benzo interaction but curious about those
Ernest Paffingwidge - Sat, 13 Jul 2019 00:22:59 EST 7Teze97q No.608049 Ignore Report Reply
Thanks, I appreciate the help. Hope you get a chill night in.
Frederick Fizzlewig - Sat, 13 Jul 2019 12:19:35 EST OHIHxMID No.608069 Ignore Report Reply
dr. m - Sat, 13 Jul 2019 19:00:35 EST 1qKXc0ke No.608081 Ignore Report Reply
Absolutely there are major interactions with some bi polar meds especially SSRIs with some opioids and a LOT of other meds, drugs, booze, and supplements both herbal and synthetic.

No offense but I don't have time to research those three, but here's how you figure it out. Figure out the enzymes that break down your mess, and find out if your meds inhibit aka slow down any enzymes. Sometimes the same enzyme that breaks them down is the enzyme that the medication inhibits.

Then check the same two things about the drug/substance you're going to use to get high. If they use the same enzyme to get broken down, it will make the active drug for both meds longer to break down, or it might make one of the two drugs get metabolized by a enzyme pathway that normally doesn't metabolize that much of the medication. Different enzymes turn the active drugs into different metabolites. Some metabolites are active drugs too, while other metabolites are totally inactive.

So yeah, that's pretty much it. Remember that not all interactions make one or both ingredients more potent or effective. An enzyme is a drug that is an enzyme inhibitor of CYP2d6 (it's either 2d6 or 3a4) combined with codeine actually makes codeine way weaker than stronger because codeine's effects are largely caused by two of its main metabolites, morphine and C-6-G.

Hope this helps. At least now I've given you a fishing rod to catch as many fish as you need, instead of providing you just three fish.
dr. m - Sat, 13 Jul 2019 19:02:18 EST 1qKXc0ke No.608082 Ignore Report Reply

This site is pretty good but it's not perfect. I suggest people use it for surface knowledge before actually researching themselves before actually consuming something.
Phyllis Trotspear - Sun, 14 Jul 2019 17:16:09 EST cO5t0GGV No.608102 Ignore Report Reply
whats up with this photo?

is he taking it because guy looks so suave or because he's smoking filling up his gas tank?
Henry Bluzzleteck - Sun, 14 Jul 2019 17:57:52 EST cQwnaJPa No.608105 Ignore Report Reply
But ive seen better info on here on occasional posts, guides, explinations n experiences
bb - Sun, 14 Jul 2019 20:22:05 EST of/iB1FU No.608106 Ignore Report Reply
this is cropped image from an fb post that went "viral"
Charlotte Bunhood - Sun, 14 Jul 2019 21:57:18 EST 2S+1FhlK No.608110 Ignore Report Reply
1563155838853.jpg -(89787B / 87.68KB, 680x906) Thumbnail displayed, click image for full size.
All of the above
Martin Chattingdin - Sun, 14 Jul 2019 23:13:06 EST nuztW1TN No.608123 Ignore Report Reply
Fucking hard. The toxicity of the Tylenol will get your liver first.

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