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Harm Reduction Notes for the COVID-19 Pandemic

Tolerance

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- Thu, 13 Feb 2020 18:10:32 EST t93J/3b6 No.613622
File: 1581635432005.jpg -(19726B / 19.26KB, 480x467) Thumbnail displayed, click image for full size. Tolerance
I did a pill of Suboxone (not sure the strength) over the course of 16 hours about a day and a half ago. I've been told it blocks Opioids.
My friend gave me 150mg of Tramadol which is an opiate as you probably already know.
If I take it today would I even get high? Or should I wait a few days for the full effect?
>>
Henry Cuttingway - Thu, 13 Feb 2020 19:14:12 EST CE4tsIs0 No.613623 Reply
I mix buprenorphine and tramadol often with no problems, I take the bupe first and then the trams and I never felt sick if anything i feel higher, the only time I did was when I was really high on tramadol and took the bupe, obviously that sucked.

So yeah I think you will feel it, or maybe not its not a very big dose.
>>
Henry Cuttingway - Thu, 13 Feb 2020 19:15:39 EST CE4tsIs0 No.613624 Reply
>>613623
*The only time I felt sick when mixing those two I mean.
>>
Nell Grandway - Thu, 13 Feb 2020 21:10:12 EST t93J/3b6 No.613627 Reply
>>613623
I only have 3 pills of Tramadol (150mg) maybe I'll wait until Saturday.
>>
m - Thu, 13 Feb 2020 23:50:24 EST lRTMMJYy No.613628 Reply
>>613627

Definitely, definitely wait until Saturday (not this Saturday, but the next). You'll be glad you did. Assuming your pill was as high as 8mg, it can partially block your receptors for easily a week or so. The average half life is like 37 hours, but can be even higher for other people. If you can, wait until Sunday after this one. If you really really can, wait another whole weekend or so and do it the following Friday, so you wait over a week.

Btw when you take the tramadol, trust me on this, take one 50mg pill, wait 30min, then take the 2nd one, wait another 30min, and then take the last pill. It's one of the few opioids that are way stronger and more enjoyable when taken staggered.
>>
Cornelius Wuffingmen - Fri, 14 Feb 2020 00:11:24 EST l/QqfqV/ No.613629 Reply
>>613628

this.

would take 1 or 2 trams before work, another after getting ready, and another at work. would be feeling nice before I even got to work, and the last one I would take at work would keep me nice and comfy working with my good pals serving up some good ol southern fried fish and seafood, burgers, etc. fuck that shit was fun
>>
Hugh Wacklewell - Thu, 20 Feb 2020 07:08:30 EST YAI1els+ No.613708 Reply
>>613622
Its an opiod btw op google for more like we did
Non fastist grammar posting
>>
Caroline Brogglemig - Fri, 21 Feb 2020 14:13:29 EST AYlrp4ua No.613725 Reply
>>613622 dont even bother. the bupronorphene and naloxone both have much higher bending affinity at the mu receptors. I would wait at least 3-4 days as bupe tends to stick around for a while long after it's effects have passed.

>>613623 see above, it's literally impossible for any opiate to cut through naloxone (or naltrexone), with the exception of bupronorphene itself.
>>
Henry Brangertidge - Mon, 24 Feb 2020 01:05:36 EST IxGcrMpY No.613764 Reply
>>613725
No its not. Tremendous amount of any opiate will do so.
>>
m - Mon, 24 Feb 2020 13:52:07 EST vgHBTjMI No.613772 Reply
>>613764
Have you ever tried cutting through ~6-12mg suboxone or subutex/day taken for at least 1-2 weeks, before attempting to "cut through" the same or next day? It's pretty much impossible. In the distant pass I tried using relatively strong PST, even various crude extracts, that totaled as high as like ~5-7lb of product, and even after waiting like ~36 hours after last bupe dose (something like one day 4mg, next 8mg, next 4mg, then 36 hours later PST), it was ~90-95% blunted/blocked by bupe. For comparison, at the time a dose of around ~1-1.5lb would have given me a solid buzz. 5-7lb felt less strong than like ~0.25-0.33lb or something.

Maybe if you solely IV using dangerous amounts of fent analogues it's possible, but anything somewhat common in a hospital setting is likely not going to work if you use bupe daily, especially anything over around ~4mg sublingual bupe equivalent per day. That's why I try to stick to around ~3mg to 4mg nasal/rectal use (~4.5-6mg sublingual) per day. Anything more and your chances of IV hospital opioid meds working plummets from slim to none.

If you want opioids to work relatively on demand for you (within ~24-48 hours), stick to doses of ~1.33mg nasal/2mg sublingual or less per day.
>>
DTMO - Tue, 25 Feb 2020 01:42:49 EST cA7HWjuL No.613791 Reply
>>613772
  1. The question is whether opioids other than bupe can cut through naloxone or naltrexone not whether they can cut through bupe.

2. I successfully got high on ludicrous amounts of PST when I was on 32mg of bupe daily after swallowing one dose to *mostly* avoid supervised dosing for the day. When I was on 6mg I imagine it would have been much easier.
Obviously I needed to use much more than usual and it's possible the euphoria was "blunted" but I definitely nodded which I didn't from any amount of bupe.
>>
Clara Gagglelet - Tue, 25 Feb 2020 05:09:26 EST xLCKwbm0 No.613792 Reply
1582625366118.png -(894677B / 873.71KB, 720x1560) Thumbnail displayed, click image for full size.
>>613791
>Using massive amounts of pst to cut throught massive amounts of bupe

This is basically the way to get desperately hooked for life, wds must've been horrible, how can you love yourself so little I cant comprehend.
User is currently banned from all boards
>>
m - Tue, 25 Feb 2020 11:14:34 EST vgHBTjMI No.613797 Reply
>>613791
Well, seeing as naltrexone has a significantly higher binding affinity than bupe, it's even harder to cut through than bupe, assuming we're talking full/nearly full receptor saturation of both/either one. Anything that can't cut through bupe can't cut through naltrexone, and if it seems like it can, chances are that person has a low nltx oral BA efficiency, or has generally taken a relatively low dose. Nltx oral BA varies heavily from person to person, IIRC by as much as like ~1000% variation.
>>
Thomas Sullermun - Tue, 25 Feb 2020 11:29:53 EST gnTwNzGH No.613798 Reply
>>613797
jolly african-american
User is currently banned from all boards
>>
>>
DTMO - Wed, 26 Feb 2020 05:19:37 EST 6GHvrNL7 No.613809 Reply
>>613792
It was certainly pretty unpleasant coming off Suboxone. I've been (mostly) clean for some years now, or at least I've managed to keep my opioid use to every few months and haven't been physically dependent since. I had a year or more with no opioids before I started dabbling again.

>>613797
True, fair call. So I guess it's limited to fentalogues and stupid and impractical doses of other agonists.

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