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- Tue, 17 Aug 2021 14:10:35 EST nNKho7Pi No.134807
File: 1629223835612.gif -(227002B / 221.68KB, 100x75) Thumbnail displayed, click image for full size. online shopping
is buying drugs off the dark net actually feasible? I've seen a lot og ppl say they've been able to do it no problem
13 posts and 3 images omitted. Click View Thread to read.
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Sidney Cannerfack - Tue, 26 Oct 2021 03:10:38 EST YtKcQwzK No.134951 Reply
>>134945
I think that poster is troll. Sounds like the same guy in the thread regarding tryptophan and anti depressants, saying dph and melatonin killed his mate lel
>>
William Chassledock - Wed, 27 Oct 2021 17:27:38 EST rw5MC1gJ No.134952 Reply
>>134951
Don't laugh at my boy. RIP Not my mate I'm not gay or nothing
>>
Martha Brookfuck - Thu, 28 Oct 2021 12:44:12 EST Y1hjkiTx No.134953 Reply
>>134952
Im sorry i dindt mean to suggest you were in a homoerotic friendship. No offense you and your boy sound like a dumb jolly african-americans. Im sorry but its how i feel

Drugs for wankin'

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- Wed, 21 Jul 2021 11:58:15 EST PnC2VAYf No.134752
File: 3.jpg -(80085B / 78.21KB, 666x69) Thumbnail displayed, click image for full size. Drugs for wankin'
So, I'm off nitrites for a while. Taking a break. Looking for something else to enhance the experience whilst wanking. Bonus points for relatively legal/relatively safe.
3 posts omitted. Click View Thread to read.
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Shit Choggleson - Sat, 23 Oct 2021 01:19:10 EST mNcMWTIo No.134946 Reply
>>134752
assuming you have a prostate and penis something that can press the prostate

More is better

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- Fri, 02 Oct 2020 21:21:20 EST rxzoyUPm No.133767
File: 1601688080882.jpg -(39174B / 38.26KB, 360x360) Thumbnail displayed, click image for full size. More is better
How risky is it to combine l-tryptophan with antidepressants (375mg venlafaxine, 45mg mirtazapine, 450mg quetiapine XR)?
11 posts and 2 images omitted. Click View Thread to read.
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Rebecca Dubblestock - Thu, 21 Oct 2021 20:50:15 EST rw5MC1gJ No.134944 Reply
>>134939
Why the fuck are you talking about my dingus? He wasn't depressed. Listen all I know is my boy took some and he didn't wake up he wasn't depressed he wouldn't do that on purpose.
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Cyril Hoshgold - Mon, 25 Oct 2021 04:32:04 EST SEV0Afff No.134948 Reply
>>134938
This man is right. The only cure for byndadrill and melanin OD is a good huff of jenkem. nb

Drugs that won't make you fail drug tests

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- Tue, 27 Jul 2021 21:43:59 EST RCnWnwX/ No.134772
File: 2.jpg -(80085B / 78.21KB, 666x69) Thumbnail displayed, click image for full size. Drugs that won't make you fail drug tests
Can we get a list of decent highs that won't make you fail a drug test? I'm planning on going into trucking and I need to quit smoking cannabis for a drug test and I need to quit drinking so much for my health.

I'll start; kratom, kava, phenibut
What else?
15 posts and 1 images omitted. Click View Thread to read.
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Esther Norrychodging - Thu, 07 Oct 2021 00:17:13 EST rbojsPJr No.134913 Reply
>>134878
Yeah I know, and there’s mofos on /opi/ jonesing because they can’t find shit on skid row. WHY isn’t there a tia epidemic, and I’ll say the same for 2m2b. You would think those two drugs would be schedule -2s but you could overnight express the 2m2b from...a very popular website and walk down the street and get tia and have the most insanely bestest time of your life within 24 hrs. Maybe everyone IS doing it and that’s why this forum is so dead lately. Who knows?
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Assman - Thu, 21 Oct 2021 20:02:56 EST W8BScVfB No.134940 Reply
>>134774
I really doubt this, research chemicals are often chemically very similar to their analogs (like fluorinated amphetamines/RC benzos).
>>
Assman - Thu, 21 Oct 2021 20:16:16 EST W8BScVfB No.134941 Reply
>>134772
Diethyl ether (unless you're being tested for alcohol), ethyl chloride, poppers (amyl/isobutyl nitrate), Modafinil/other -afinils, DPH, Cyclazodone.

ID for these pills?

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- Fri, 23 Aug 2019 22:26:35 EST NY6w/vEj No.132637
File: 1566613595867.jpg -(29833B / 29.13KB, 509x960) Thumbnail displayed, click image for full size. ID for these pills?
Got these from a friend who didn't seem to have any idea for what they contain. He said something about them begin used for people with schizophrenia, "but they can make you high".

I have checked pill ID-services but without getting any matches.

They say 50 on one side, and blank on the other side.

I live in Scandinavia, 5c coin is there for for scale.
10 posts and 1 images omitted. Click View Thread to read.
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Cornelius Muzzledock - Tue, 11 Aug 2020 01:33:18 EST IRmajXhU No.133585 Reply
1597123998142.webm [mp4] -(93037B / 90.86KB, 852x480) Thumbnail displayed, click image for full size.
>>132637

dude the fuck did you do to that nikel?

its got like 30 chins
>>
Betsy Turveyfield - Mon, 18 Oct 2021 16:52:42 EST /IOIAgAv No.134925 Reply
On one side it has 377
>>
DTMO - Wed, 20 Oct 2021 18:56:22 EST mr88DrN/ No.134935 Reply
>>132695
>Quetiapine

That's the name of the drug. It's an antipsychotic, it's not fun. It will great increase the effects of alcohol but even then still not much fun.

Not recreational even though you are 12.

Where is my cotdamn Poly-drug discussion board?

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- Tue, 19 Oct 2021 18:35:36 EST eX5OzUjN No.134929
File: 1634682936193.jpg -(289089B / 282.31KB, 1089x1074) Thumbnail displayed, click image for full size. Where is my cotdamn Poly-drug discussion board?
This is the final night of my monthly Bacchanalia...

It would just be called Tuesday if the whole thing wasn't predicated on my cunt of a GP giving me the smallest amount of Xanax one can prescribe.
The pills are just enough to last me 3-4 nights, but when combined with those other goodies and maybe 3 hours of sleep through the whole event, it produces a pretty singular state of mind. The whole thing is very eremitic and spiritual. I couldn't care less about a young, hot piece of ass right now...

So off I go... farewell world! I soon hope to be reuniting with my disembodied friends and their shady shapeshifting cousins.... and to find a way to buy Ripple in this fagola country. Xanax inspires all sorts of investment ideas in me. Not sure how sound they are but it sure does remove my inhibition to not take a financial risk. Has anyone else noticed that?
>>
Thomas Greendale - Wed, 20 Oct 2021 08:43:48 EST eX5OzUjN No.134930 Reply
>>134929

This was actually my first time throwing whippits into the mix. That stuff is retarded. xD
>>
Thomas Greendale - Wed, 20 Oct 2021 08:55:39 EST eX5OzUjN No.134931 Reply
>>134930

Last night was pretty disappointing. I somehow wasn't exhausted enough to get into that weird mental space. I did hallucinate in the bathroom at one point and had this tiny many in a cloak and carrying a staff making all kinds of gestures at me. He kept changing back and forth from that and a shirtless man dancing and spinning around.

I love hallucinations like that. They're like the mini shadow people. (Real shadow people are fucked up... not a fan even though they're fascinating). I'm still trying to figure out how to "hear" them. They're always moving their mouth and gesturing like they're communicating to me but I don't know what they're going on about.

I remember once I saw a whole cast of these little men partying their ass off, dancing and throwing up and fucking each other. It was hilarious.

The brain is so strange...
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Thomas Greendale - Wed, 20 Oct 2021 08:59:13 EST eX5OzUjN No.134932 Reply
tiny man in a cloak*

He looked like an angry, dwarf mage.

Air horn huffing general

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- Sat, 29 Aug 2015 19:31:31 EST yG8wyAoI No.124207
File: 1440891091997.jpg -(55676B / 54.37KB, 238x443) Thumbnail displayed, click image for full size. Air horn huffing general
Yall mother fuckers gonna get loud?

My land lord keeps asking me whats with all the noise. I used to tell him it was a sports thing but I think he's getting suspicious. What should I tell him?

What's your favorite brand of horn? I like seachoice. Their cheap and aren't full of bitter shit.

GONNA GIT LOUD!
244 posts and 56 images omitted. Click View Thread to read.
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George Handledadge - Thu, 30 Sep 2021 05:03:59 EST EUzqNQGm No.134898 Reply
Keep getting strange looks whenever I sneak to the bathroom and get loud
User is currently banned from all boards
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George Handledadge - Thu, 30 Sep 2021 05:05:16 EST EUzqNQGm No.134899 Reply
I switch brands to avoid tolerance
User is currently banned from all boards

Legal GABAergics

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- Wed, 28 Jul 2021 21:43:37 EST qzawkDzY No.134777
File: 1627523017721.png -(12840B / 12.54KB, 719x269) Thumbnail displayed, click image for full size. Legal GABAergics
Anyone have any experience with legal, fairly easily available GABAergics? For example, GBL, 1,4-B, 2M2B, and more common ones like Phenibut & Gabapentin (Think you need a prescription to obtain Gabapentin though, but it's not scheduled)
How do you like these substances? Where did you acquire them? I want to try 2M2B in particular because it sounds awesome, but I worry about impurities in the stuff you can find easily online, even if it advertises a high concentration. Anyone take the risk?
4 posts omitted. Click View Thread to read.
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Molly Fuckingford - Sun, 05 Sep 2021 19:04:10 EST VlDIpdpc No.134850 Reply
I am a 1,4- BDO chronic user. This shit works no more euphoric, i can just feel normal, sleep or vomit.
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press - Thu, 23 Sep 2021 18:27:34 EST nl1M4WWH No.134882 Reply
>>134777
should you be located within the EU it is ridiculous how easy GBL is to source, seeing as most countries only placed GHB-salts on their respective schedules.

for the vendors ive tried, id bet on the different grades being a rip off.
im also fairly certain that a few of the ones i frequented mustve pulled exit scams, all in the game. should you be within the EU it might be a good idea to avoid domestic vendors/shippers, as europol has bigger worries and bureacrats almost hate eachother as much as regular people hate them.

but unless youre going to actually turn it into a GHB-salt, the purification is a bit of of whore.

apart from GBL and good old alcohol ive only tried baclofen and pregabalin.
and baclofen might be nice to potentiate an opioid high or get rid of deep muscle tissue tenseness, but it wasnt worth it.
pregabalin was pretty nice though.

no idea how to source either, except for working in a hospice or the web.

i also still havent managed to actually pick a fly agaric, i couldve sworn they were very common around my area during my very early teens.
>>
Hedda Worthingshaw - Thu, 23 Sep 2021 23:01:30 EST iz773ja8 No.134883 Reply
>>134882
Fly agaris is stupid easy to buy online. Look for lithuanian vendors on google. Pretty cheap too

2-methyl-2-butanol or 2M2B

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- Sun, 19 Sep 2021 09:41:00 EST rbojsPJr No.134875
File: 1632058860862.jpg -(161997B / 158.20KB, 900x900) Thumbnail displayed, click image for full size. 2-methyl-2-butanol or 2M2B
I want to discuss this thing. There's basically a blackout of information online regarding the use of it, which perplexes me because it seems like the holy grail of alcohol. It doesn't harm your liver since it isn't even metabolized by it (or at least that's what I've heard) and since it's not metabolized by the liver it stays in your system for a long time, and you only need like 1-3mL to get a good buzz off of it. I would think something like this would be all the craze, but I'm unable to get any REAL concrete information about it anywhere. So I was wondering if anyone on here could enlighten us about the use of 2m2b. I mean, is it safe? Is it really as good as it seems?

What happened to our boy Dangerous Dan

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- Thu, 28 May 2020 18:21:23 EST /SWMU1Ah No.133415
File: 1590704483580.gif -(788018B / 769.55KB, 500x281) Thumbnail displayed, click image for full size. What happened to our boy Dangerous Dan
Or whatever his name was. What happened to him?
1 posts omitted. Click View Thread to read.
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driven !FTPgBqDDy. - Thu, 16 Sep 2021 03:52:41 EST UiHmJL// No.134870 Reply
he was just trainwrecking his life on the internet. the videos went down. i kept the "buttery bible" one tho. iirc he mainly posted on minichan (under a handle that only real ones remember) and was doxxed at some point by someone called "The New Zealand Troll".
>>
Simon Dollystone - Fri, 17 Sep 2021 00:46:22 EST BsOjSaaE No.134871 Reply
>>133415
Rofl I forgot about Danger Dan. Wasn't he constantly doing crazy shit like stealing traffic cones and huffing spray paint?
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Jenny Shakecocke - Sat, 16 Oct 2021 05:17:05 EST h8ltlvI3 No.134924 Reply
Could've sworn it was Dave, not Dan?
User is currently banned from all boards

GHB Recipes?

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- Tue, 12 Jan 2021 04:47:17 EST VZaYrO9n No.134304
File: 1610444837507.jpg -(68681B / 67.07KB, 412x378) Thumbnail displayed, click image for full size. GHB Recipes?
To the drain cleaner drinkers of 420chan - are there any among you who have produced their own GHB, and if so - how did you go about doing it?
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DTMO - Sat, 11 Sep 2021 06:54:18 EST QKXleDTB No.134863 Reply
>>134304
If you can legally buy GBL or 1,4-BDO in your area then just do that. The prodrugs (especially GBL) are better anyway. If not you probably are not down for the sandmeyer reaction from GABA.
User is currently banned from all boardsUser is currently banned from all boards
>>
Phineas Blythefield - Sun, 12 Sep 2021 23:47:07 EST ZrEH+ipo No.134866 Reply
1631504827970.gif -(123239B / 120.35KB, 232x200) Thumbnail displayed, click image for full size.
>>134304

Ya get your Gs, and your Hs, and your Bs. Then you put em' in a jar with a luttle bit of vodka and ice, and ya mix em' up real good, for the good times, ya hear?

Inhalants

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!Xn5AX./Uqk - Sat, 04 Sep 2021 00:47:35 EST jSADRNsS No.134843
File: 1630730855257.jpg -(81400B / 79.49KB, 278x512) Thumbnail displayed, click image for full size. Inhalants
I am not sure if this belongs on this board, but i'm gonna post it. I have a bottle of Shoe Goo and I am not 100% sure if I can get high off it.

Anybody into inhalants here? can I get high off this shit? Is it safe to do so? what about if i've been drinking? am I gonna fuck myself up permanently by doing it once? I'm really tempted to do it rn. How do I even do it?
1 posts omitted. Click View Thread to read.
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Caroline Finkinchire - Thu, 09 Sep 2021 16:44:00 EST tJmDFYwr No.134859 Reply
>>134843
The only inhalant anybody should ever do is nitrous oxide. Amyls are apparently pretty awesome too but I've never tried it because they have more damage potential.
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Albert Blingerwater - Thu, 09 Sep 2021 18:04:00 EST /3klzowo No.134860 Reply
the solvent in glues is usually toluene which shreds your brain
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DTMO - Sat, 11 Sep 2021 06:52:13 EST QKXleDTB No.134862 Reply
>>134843
Inhaling solvents is in no way safe. It's not common but yes you abso-fucking-lutely can die using inhalants a single time. Cops here are not meant to chase chromers (paint huffers) because they can have a sudden cardiac event from being startled.
User is currently banned from all boardsUser is currently banned from all boards

Resetting tolerance using NMDA-antagonist

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- Wed, 01 Sep 2021 13:16:34 EST ejJxYhDe No.134834
File: 1630516594671.jpg -(7866B / 7.68KB, 231x218) Thumbnail displayed, click image for full size. Resetting tolerance using NMDA-antagonist
Tose of you who have succeeded with decreasing / resetting tolerance to substances/medications could you tell your story. How would you recommend resetting tolerance using nmda-antagonists like memantine?

Eg. if someone has been taking 1 month of 1mg klonopin, 3rd month 2.5mg klonopin, 5th month 5mg klonopin etc... Then want to reduce their tolerance, how long would they have to take Memantine for example for the tolerance to be reset?
8 posts and 2 images omitted. Click View Thread to read.
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Matilda Duckforth - Wed, 08 Sep 2021 01:24:04 EST HFBsEeGl No.134855 Reply
>>134854
Besides, it was only that mematine thay i was foolishly eyeballing nothing else really. I mean 10 mg spoon seemed not too dangerous but shit mematine weighrd a lot. I did look up half lives but didnt put in the effort to practise proper harm reduction like buying a fucking scale,cheap ass scale haha. Guess i was lucky that i didnt die (what a shame)
>>
Jarvis Haggleben - Wed, 08 Sep 2021 04:16:04 EST nnHmF9Dz No.134857 Reply
>>134855
I think you should buy a better scale homie if you plan on using mematine again. super long lastingfull on NMDA antagonist that can fuck you up bad if you try holeing on it, that one erowid trip report about some dude taking like three 300mg+ doses of mematine in one night scared me right off intentionally taking big doses of it. The guy got so fucked up, he was found on his living room floor by his parents a day or so later, could barely string a word together let along a sentence and it took him months to recover from that.
>>
Jarvis Haggleben - Wed, 08 Sep 2021 04:29:28 EST nnHmF9Dz No.134858 Reply
>>134857
>string a word together let along a sentence
oof im talking to myself again but was i wrong about what i said when i replied to my own post like a demented fool?

The least neurotoxic drugs

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- Tue, 27 Jul 2021 22:04:18 EST GTqGBDTN No.134773
File: 1627437858927.jpg -(6376B / 6.23KB, 304x165) Thumbnail displayed, click image for full size. The least neurotoxic drugs
Kan someone grade the least neurotoxic substances there are.

For example I reckon morphine isnt that neurotoxic since its a natural substance.

Which of the GABA/benzo drugs are the least neurotoxic, kan you grade from 1-5 list . Like, comparing Pregabalin with Alprazolam, which of them is least neurotoxic.

And how to take these substances in a manner that doesnt harm the physical self in the long term? Like looking at half life elimination. should one after ingesting a substance, then let it get out the system before using it compulsively? anyone a pro at this?
4 posts and 1 images omitted. Click View Thread to read.
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Eliza Pangerway - Mon, 16 Aug 2021 03:26:17 EST SEV0Afff No.134802 Reply
>>134780
Morphine isn't a direct neurotoxin, but chronic and sustained opiate addiction is cumulatively neurotoxic through reduced oxygen flow to the brain.

>With more sensitive and sophisticated approaches for assessing neuronal injury, emerging evidence suggests that sustained morphine exposure may be intrinsically neurotoxic. While there has been sporadic experimental evidence especially using cell culture models that opiates can be cytotoxic to neurons, as well as other cell types, only a few clinical studies reported modest astrogliosis in opiate abusers [87]. Rarely, severe astrogliosis is reported with heroin abuse [87-89] or in individuals inhaling volatilized heroin vapor [89, 90]. By contrast, in another study, dopaminergic function, as assessed by tyrosine hydroxylase (TH) terminals, was significantly reduced in the nucleus accumbens; while an index of serotonergic (5-hydroxyindoleacetic acid) function and TH was variably affected in the putamen and caudate nucleus [91]. Reports of increased perivascular infiltrates of lymphocytes and macrophages were also noted [92]. However, the nondescript nature of the gliosis in the above instances was potentially attributable to the physical and psychological "side effects" of addiction, including poor nutrition, poor health and lack/avoidance of medical care, and/or a marginal life-style [89, 90]. More recently, hyperphosphorylated tau was described in hippocampal neurons of a carefully characterized cohort of preferential opiate abusers [93]. In this cohort, the authors were careful to control for risk factors such as age and neurodegenerative or infectious diseases that could confound the interpretation of the deleterious effects of chronic opiate abuse per se [93]. Similar neuropathology characteristic of the aged brain involving tau hyperphosphorylation and increased amyloid and amyloid precursor disposition was seen in opiate abusers less than 40 years of age [94].
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John Brudgededge - Fri, 03 Sep 2021 17:26:05 EST 0087E+g/ No.134841 Reply
>>134773
>For example I reckon morphine isnt that neurotoxic since its a natural substance.
> isnt that neurotoxic since its a natural substance.
Not to be a dick man, but you realize that nature is rife with toxic plants and substances, right? This is some really shitty, dangerous logic.

Also, gabapentin and pregabalin do not directly affect GABA and have an extremely modest effect on its metabolism to the point of being clinically negligible. Gabapentinoids (mainly just those two... technically phenibut is a gabapentinoid more than it is GABAergic, but its binding affinity on alpha-2-delta sub-unit containing VDCCs, the target of gabapentinoids, is so much less than gabapentin and pregabalin, and you take such high doses of those in comparison, as well as the fact that its an agonist of GABA-B receptors which are metabotropic rather than ionotropic like most fast acting drugs means that the duration of its activation of GABA-B receptors far are exceeds the duration of its actions on the a-2-d sub-unit VDCCs given its relatively short half-life of 5 hours and lack of active metabolites, making it effectively more of a GABAergic than gabapentinoid overall) far safer than benzos or any GABAergic drugs for that matter.

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