Leave these fields empty (spam trap):
You can leave this blank to post anonymously, or you can create a Tripcode by using the format Name#Password
[i]Italic Text[/i]
[b]Bold Text[/b]
[spoiler]Spoiler Text[/spoiler]
>Highlight/Quote Text
[pre]Preformatted & Monospace Text[/pre]
[super]Superset Text[/super]
[sub]Subset Text[/sub]
1. Numbered lists become ordered lists
* Bulleted lists become unordered lists


Discord Now Fully Linked With 420chan IRC

Psychedelics and euphoria

- Thu, 03 Oct 2019 13:00:19 EST YuzU445o No.898877
File: 1570122019770.jpg -(15088B / 14.73KB, 480x360) Thumbnail displayed, click image for full size. Psychedelics and euphoria
Do psychedelics give any euphoria? I believe they don't since they work on serotonin receptors not dopamine. Have you ever gotten euphoria from mushrooms or any other psychedelic drug?
Baltazaras Aklasis - Thu, 03 Oct 2019 14:53:27 EST kfiGoZKH No.898881 Reply
1570128807185.png -(2478436B / 2.36MB, 1521x928) Thumbnail displayed, click image for full size.
Last time I took acid there was a short lasting wave of euphoria after the peak.
It's like during the peak I felt tired, physically slow and confused, but after a while a rush of energy came over me, I became more giggly, just glancing throught the window and seeing the world and the sunset made me think "god fucking damn I love this place", "i fucking love life" and stuff like that.

It lasted for about 20 mins, half an hour at most - the unconditional positivity died down quickly when I started thinking philosophically about existance and my experience (not that what I was thinking about was negative, it just put me in a different mood), the blast of energy lasted for a bit longer.

Euphoria on psychedelics isn't a guarantee, but it can happen, and when it does, it feels great. Better than euphoria from ecstasy ime.

I'm pretty sure there was a thread about euphoria from drugs, if not on this board, then probably on /other/
Caroline Bunforth - Thu, 03 Oct 2019 18:31:54 EST O+nLOUrh No.898889 Reply

yes they do

mdma also works on serotonin and that is highly euphoric
Wesley Cherryway - Thu, 03 Oct 2019 23:25:03 EST o4XnNFvL No.898902 Reply
My first acid trip was insanely euphoric. I've had other euphoric acid trips as well. I've never experienced anything else quite like it.
George Fublingwater - Thu, 03 Oct 2019 23:26:04 EST aQcRuewx No.898903 Reply
The brain is not as simple as "dopamine = euphoria/pleasure". Serotonin is a neuromodulator, it tunes the sensitivity of certain neurons to various other neurotransmitters, dopamine included, as well as can stop or promote its release. Even when a neurotransmitter is not recognized specifically as a neuromodulator, the levels of said neurotransmitter in certain areas of the brain cause the release and inhibition of others as a response to that.

Hell, dopamine doesn't even directly stimulate neurons like some neurotransmitters do, it functions as part of a second messenger system, meaning the stimulation of a dopamine neuron results in the release of various other chemicals that actually bring about the electrical activity. Think about how neurons even function. They work by absorbing and releasing electrolytes like calcium and sodium in order to alter how excitable they are (membrane potential), and once they receive enough stimulation from chemical messengers an action potential occurs, which is a nerve impulse. These nerve impulses chain together in networks and cause specific patterns of neural oscillation (brain waves) that wind up interacting with other oscillations (either resonating or canceling out through deconstructive interference), and all that winds up resulting in conscious perceptual experience.

Through experience reports alone you ought to be able to gather that psychedelics cause euphoria.

Yes, but it releases far more serotonin than dopamine, and it releases less dopamine than amphetamine or methamphetamine. Yet, many people, myself included, would tell you that MDMA is far more euphoric (ridiculously so, IMO) than amphetamines or meth are.

All dopamine, serotonin, norepinephrine, and many others but those main three, do are affect the excitatory activity in certain parts of the brain (and to a much, much lesser extent, through indirect downstream action, inhibitory action), mostly by affecting, mostly stimulating, glutamate activity. Glutamate is the main excitatory neurotransmitter and accounts for upwards of 90% of the synaptic connections in the brain.
Shit Huzzlestone - Thu, 03 Oct 2019 23:55:36 EST jl4B8s9v No.898905 Reply
sure they do. acid and mescaline are incredibly euphoric, and even on tryptamines I feel that joy that's more of an equanimity that's not a passionate joy but a ataraxia and deep satisfaction.
Priscilla Handleford - Fri, 04 Oct 2019 00:04:15 EST jlcoTZD+ No.898906 Reply
On lower doses, yes. I had a shrooms trip that was around level 2 - complete euphoria and peace of mind, most awake I've been in my life and I say this as someone who's currently on 40mg adderall
Charles Ceffingdire - Fri, 04 Oct 2019 05:53:49 EST 79BfIwEN No.898907 Reply
i find high doses of just about any psychedelic to be euphoric as fuck really, it's just a different kind of euphoria... kind of in the same way there's a difference between the euphoria produced by adderall/meth and MDMA, or from substituted amphetamines and stimulating dissociatives like PCP and 3-MeO-PCP. The euphoria is qualitatively quite different, but it's euphoria all the same.
Priscilla Handleford - Fri, 04 Oct 2019 06:04:03 EST jlcoTZD+ No.898908 Reply
Iunno I've also had level 4ish trips I wouldn't really call it euphoric, not sure if 5 would be the difference
Charles Ceffingdire - Fri, 04 Oct 2019 07:26:37 EST 79BfIwEN No.898909 Reply
that makes sense to me, i'm pretty sure it's just my personal reaction to psychedelics. any dose i take i find euphoric and blissful, it's just the way it's euphoric and blissful changes based on how much I take.
Walter Blabbertere - Fri, 04 Oct 2019 16:28:40 EST YuzU445o No.898916 Reply
Meth high is the best thing in the world. Nothing comes close to it.
George Honnerhood - Fri, 04 Oct 2019 19:05:16 EST c3gflUrd No.898918 Reply
This is actually debatable. There seems to be 2 kinds of people, those who respond better to downers and those who respond better to uppers. Depending on which you are, either MEth is the greatest thing ever, eihter * IV opi of choice* is

The real answer might be that meth/heroin speedball is the best, but I can't say as I haven't gone down that path
Emma Blatherridge - Fri, 04 Oct 2019 19:15:50 EST O+nLOUrh No.898919 Reply
Tried it a handful of times and it was never anything special. Slightly cleaner feeling than taking too much adderall but that's it. In fact as far as stimulants go nothing ever came anywhere near as close to euphoric for me as 4-MMC. And as far as opiates go there are plenty of ones known to be more euphoric that heroin, like dilaudid and opana, but I've never felt as good from any single pure opioid compound as I had from full spectrum poppy extracts.

Basically what I'm trying to say is that there isn't one solid answer as to which drug is the most euphoric as everyone is different and all things go out the window once you start looking at combinations of drugs. Especially combinations made in the same plant by nature, just look at how much better the high is from weed than that of pure THC.
Ebenezer Blatherman - Sat, 05 Oct 2019 00:46:17 EST jlcoTZD+ No.898923 Reply
My point is kind of more that euphoria is "built-in" at lower doses, higher doses it's more subjective and circumstantial
It can be trivialized but not that simply. Dopamine = euphoric rush, serotonin = well-being if I really had to generalize.
Personally I have a reason for never trying meth or coke. Those dreams where you experience pure bliss with no bullshit from the real world then you wake up and are depressed for days- I don't need this scaled up in the form of drugs that'll destroy my body. Coke or MDMA is the hardest shit I'd try
Archie Fanham - Sat, 05 Oct 2019 01:28:49 EST O+nLOUrh No.898924 Reply
Coke is the most over hyped bore of a high I've ever tried. And amphetamines of all kinds, even meth, never made me feel "good". Just gave me a lot of focus and energy but there was always a very dirty body load that strongly outweighed any sort of euphoria. I'm not saying you should try them, just saying that for a lot of people they are no where near as good as the legends about them make them seem. I for one feel way more euphoric on a good LSD trip than any amphetamine had made me feel.

>tldr: for me coke and meth are horribly boring highs with gross comedowns to the point that I even turn them down when they're free
Eliza Sinnertatch - Sat, 05 Oct 2019 03:07:27 EST ownexa+6 No.898925 Reply
hate to be this guy, but smoking meth is way different lol.

I dont reccomend it to anyone.
Archie Fanham - Sat, 05 Oct 2019 04:47:02 EST O+nLOUrh No.898927 Reply
I was talking about meth as well, and yeah smoking was the main route of ingestion used. Snorted it a couple times but that burn isn't really worth it. And sometimes my buddy would put it in with his coffee grounds and call it "Spartan Coffee". But by far smoking was the most common. The high was usually just hyper focus, maximum energy, and an extreme urge to jerk off the entire time. Uppers just never really clicked with me.
Eliza Deddlemat - Sat, 05 Oct 2019 06:40:22 EST OexjATri No.898928 Reply
I envy you. LSD is my favorite substance, but a large part of it for me is the increased wakefulness, and lengthy trip.

Unfortunately, I can't do acid every day, or even every weekend. I've been using amphetamines on a regular basis to stay 'up', and finding the headspace very similar to LSD at times.

I'm worried that all along I was just into psy's because I like to get high, and now that I've found a more powerful/efficient means to do so, I'll lose touch with acid... not to mention a high risk for physical addiction and prioritizing my life to be a tweaker.

TL;DR stick to acid, kids.
Archie Fanham - Sat, 05 Oct 2019 10:05:18 EST O+nLOUrh No.898932 Reply
Honestly man, as a young teen I heavily abused my and my friend's adderall and concerta scripts and maybe just blew out those receptors before I ever had a chance to get to meth. But then again, heroin never seemed worth the price of admission for me but holy fucking balls do I love whole poppies as much like I like cute redheads. I might just have some weird ass chemistry going on.
Reuben Fanworth - Sun, 06 Oct 2019 15:27:16 EST bkUwiMeu No.898962 Reply
the most euphoria i've ever had was from mushrooms, and i've had quite a lot on lsd, 2c-e, 4-ac-dmt, etc. really all tryptamine and def phens. it depends on your mindset 100% though, you can also get dysphoria. heavily dependent on you. although, mdma sees to force euphoria, albeit prob not counting in this case.
Ernest Puttingsag - Sun, 06 Oct 2019 15:56:58 EST c3gflUrd No.898963 Reply
shrooms+DXM gave me the most euphoria personally. I added nitrous to the mix and while things definitely became wilder, I wouldn't say they were more euphoric
Fanny Hublingstone - Mon, 07 Oct 2019 13:53:07 EST bfdi1EF7 No.898978 Reply
Mushrooms can't give any euphoria. You may feel amazed by the visuals when you try them first time, but that's about it.
Awe' God !!Bwteoy2D - Mon, 07 Oct 2019 15:33:35 EST eqA4Nfhs No.898986 Reply
This is some truly hilarious content, brother, much obliged.
Rebecca Brengerdock - Mon, 07 Oct 2019 15:44:55 EST JeOl3lYc No.898989 Reply
Subjectively they can be very pleasurable at times. I don't know whether this qualifies as euphoria.
Nell Croffingdut - Tue, 08 Oct 2019 11:34:15 EST bfdi1EF7 No.899052 Reply
If you're 15, that might be the case. Mushrooms are great for teenagers getting into drugs.
Oliver Gettingwater - Tue, 08 Oct 2019 13:06:23 EST c3gflUrd No.899055 Reply
1570554383427.png -(148482B / 145.00KB, 299x306) Thumbnail displayed, click image for full size.
This is some pretty shitty bait sempai. Are you even trying?
Awe' God !!Bwteoy2D - Tue, 08 Oct 2019 13:13:47 EST eqA4Nfhs No.899057 Reply
lel, but believe me it would actually work just fine in this forum, senpai knows what he's doing
Nell Croffingdut - Tue, 08 Oct 2019 13:56:55 EST bfdi1EF7 No.899060 Reply
How am I baiting? You can't deny that the only people impressed by mushroom effects are teenagers. ''Wow man, I was in different dimension'' No adult would say that. When you're an adult, you do opiates or stimulants because they're actually worth the money.
Betsy Goodwater - Thu, 10 Oct 2019 11:05:48 EST bb1s62WI No.899101 Reply
just popping in to say I dropped 2 tabs and took 500mg dxm this past weekend and smoked DMT during, which was one of the best feelings I've ever felt in my life.
if that's not euphoria I dont know what is.
Augustus Guvinglock - Thu, 10 Oct 2019 14:09:38 EST KR4xgJuo No.899102 Reply
cocaine shuts off blood supply to everything it touches where as mushrooms and lsd make connections in your brian that arent usually there, its smarter to not do cocaine and take lsdd
Archie Shittingshit - Sat, 12 Oct 2019 07:26:48 EST LywZUfmH No.899150 Reply
Mind you, psychedelics make connections where there aren't (a lot) but they also shut down connections where there are (a lot).

That's why (lots of) alcohol and psychedelics are such a shitty combo. Because the alcohol will shut down the parts that the psychedelics try to activate, and you'll just end up like a psyched out drunk completely lost.

I have never heard about cocaine messing with bloody flow though. Then again, I am not a big cocaine fan. Can you maybe explain a bit more about it? Because it does fit in with anecdotal talk I've heard, about cocaine and psychedelics being a really shitty combo.
Which is a bit weird, because typically stimulants and psychedelics are pretty good, especially when you start getting in heavy (shroom) dosages and you want some extra help making sure you'll remember the whole trip when you're sober again.
Jack Sammerpene - Sat, 12 Oct 2019 07:41:14 EST S6AWiUEB No.899151 Reply
Your view of cocaine is as retarded as his view of psychedelics. The effect I'm guessing you're referring to is cocaine's local anesthetic properties, which is mediated by its actions as a sodium channel blocker. That isn't the same thing as shutting off blood supply. The only other thing you could be talking about is its vasoconstrictive properties, which is again pretty retarded because 5-HT2A agonist psychedelics cause vasoconstriction too. Cocaine "shutting off blood supply to everything it touches" isn't the same as it preventing your brain from making connections in your brain that usually aren't there. Fuck's sake, literally anything you think, do, or consume cause new connections to form in the brain.
Archie Shittingshit - Sat, 12 Oct 2019 16:41:23 EST LywZUfmH No.899162 Reply
Thanks for the post mate. Might you have an idea where the anecdotal talk about cocaine and psychedelics being a bad combo is based on?
Arron Jolly - Sat, 12 Oct 2019 19:38:56 EST HEQZyD8E No.899170 Reply
They have taken me to the highest of highs and to the lowest of lows, they are what you want them to make you feel op
Fuck Hendleford - Sat, 12 Oct 2019 19:49:07 EST HrJxZf6f No.899172 Reply
>trying to gauge how good you'll feel on psys by their pharmacokinetics
They aren't that kind of drug. Even morphine gets different reactions from different people.

Report Post
Please be descriptive with report notes,
this helps staff resolve issues quicker.