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MXE Synthesis

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- Sat, 13 Aug 2016 11:00:34 EST xPDjzOso No.78148
File: 1471100434384.png -(16419B / 16.03KB, 220x185) Thumbnail displayed, click image for full size. MXE Synthesis
So, theoretically speaking, how hard would it be to synthesize MXE at home assuming one had no real chemistry experience or knowledge?

I'm curious because this stuff has gone the way of quaaludes and nobody is making it anymore, and after reading /dis/ for a while I've been wondering for the past few days what would making a batch imply in terms of proficiency, equipment and reagents.
11 posts and 1 images omitted. Click View Thread to read.
Schepperschop - Sat, 10 Sep 2016 19:23:26 EST xTIigKo1 No.78227 Reply
1473549806673.jpg -(836490B / 816.88KB, 2592x1944) Thumbnail displayed, click image for full size.

Zika Virus: Is it an ELE?

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- Sun, 28 Aug 2016 17:35:29 EST 5UnrR+r2 No.78188
File: 1472420129173.jpg -(72252B / 70.56KB, 1037x784) Thumbnail displayed, click image for full size. Zika Virus:  Is it an ELE?
I just had an interesting short chat with a store clerk of a quickie-mart type of place. What he said actually freaked me out. He said that Zika reached our area (Florida) and how it'll take a month before money is released to try to combat the problem. But this wasn't the interesting bit, the interesting bit was him saying: "This is bad because mothers can't have babies. Without babies, we will go extinct; an extinction level event (ELE)." It was one of those moments that it didn't strike me just how dangerous Zika is to the human race. I saw it similar to the Ebola scare we had.

I hoped to him that perhaps science will solve the issue. He replied by saying we aren't exactly Star Trek level so you never know.

It could be that as a store clerk he is searching for something exciting because life as a store clerk is anything but. It could also be a covert-Christian trying to prolysetize. So science-peeeps that may be reading this, set me straight. Why shouldn't I worry about this problem, at least not overly so?

I am sure that I am missing something that makes this problem not as major as the store Clerk made it out to be but don't know where to start. Couldn't we simply make a vaccination? Couldn't we, in the worst possible event, simply do in-vitro fertilization in which the child has a natural immunity to the virus?

What could we do? This is actually scaring me.
Nell Snodstock - Sun, 28 Aug 2016 18:55:38 EST 5UnrR+r2 No.78190 Reply
Thought you were quoting Game of Thrones for a moment there.

Are adults ok? I heard about the blood-brain barrier and how because of this barrier can't affect an adult brain. Is this true? I read an article stating that this may not be true and can cause alzheimers or other conditions.

Do you think the CDC or some organization can do a good job on this issue?
Esther Buzzcocke - Wed, 07 Sep 2016 21:54:12 EST Z4xgskMZ No.78223 Reply
It's currently gridlocked to the areas around the equator that have egypti and other tropical mosquito species in terms of mosquito transmission.

The bigger issue is that it's sexually transmitted. I think the main vector is going to be humans. As long as it's still a popular trendy scary disease and the people who have it are on lockdown then it won't spread far enough for the kind of damage you're talking about. I think a vaccine is in the works but who knows.

Molecular sandbox

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!/sly9iFJgg - Wed, 22 Jun 2016 14:54:50 EST H8Fdbu5S No.77990
File: 1466621690969.png -(291146B / 284.32KB, 1271x969) Thumbnail displayed, click image for full size. Molecular sandbox
I found a great free molecular simulator, at http://avogadro.cc/wiki/Main_Page . It's real easy to use, but the fucking thing crashes without warning or apparent reason. There's seemingly nothing I can do to make it run. The only circumstance it DOESN'T crash in is when I first load it and haven't added any atoms/loaded a save.

So unless y'all have a fix that I haven't tried, I'm looking for a program with a similar sandbox-style modeling.
10 posts and 3 images omitted. Click View Thread to read.
Bombastus !uYErosQbLM!!Mybq1UbK - Sat, 03 Sep 2016 17:34:10 EST Req4jw5M No.78217 Reply
I'm absolutely computer inept.
trypto - Tue, 06 Sep 2016 16:52:28 EST 6/EmvHqc No.78221 Reply
I'm not too familiar with molecular modelling, but I know it uses similar computations as neural networks. That is, it's mostly linear algebra, and having a good graphics card is very useful. In the NN world, an NVIDIA chipset will get you much further because it understands CUDA instructions. On the other hand, AMD chipsets use OpenCL, which is less supported. Last time I tried out modelling software (5 years ago), this was also the case. So I would look for a laptop with NVIDIA graphics... Except I've also read bad reviews about NVIDIA shit in laptops. Maybe that's old, or linux-specific, but be sure to check out reviews.

I sincerely doubt you'll be able to do any modelling on a laptop under $3k. On the other hand, you could probably build a PC with a lower midrange graphics card for $600 that could outperform the $3k laptop.
Clara Cremmerkedge - Sun, 09 Oct 2016 21:50:55 EST mC4q4Hy7 No.78278 Reply
1476064255773.jpg -(58482B / 57.11KB, 401x500) Thumbnail displayed, click image for full size.

Anti-GMO nutjobs

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- Fri, 05 Aug 2016 23:27:16 EST JmjQz8t7 No.78130
File: 1470454036382.jpg -(36320B / 35.47KB, 400x267) Thumbnail displayed, click image for full size. Anti-GMO nutjobs
Man I was having such a good day today at work.

There I was, being all kickass at my job, and SOMEHOW the topics of organics and GMOS came up. I am so for GMOs its not even funny - organics, hey, but what you want but don't try to take away my options. Also, don't tell starving kids in India what to eat while they're dying? Follow those two rules and all will be well.

Man, I had no idea. These are people who work for the government, and it was liked I whipped out a baby and started to slaughter it in front of them. I didn't state my opinion, I just appeared neutral, but I was angry inside. How can these people profess for being about knowledge and the cutting edge, but believe that pesticides don't wash off of food? And that " We don't know enough about it to eat it" while eating cheese?! In front of me?!

I'm still mad, and have to go back to work tomorrow. I hate being a pot smoking skeptic sometimes, I feel like a damn unicorn.
7 posts and 2 images omitted. Click View Thread to read.
Caroline Babblelork - Tue, 30 Aug 2016 18:05:38 EST 82e0TSBV No.78197 Reply
Roundup is less toxic than the herbicides they were using before. It's also pretty easily eliminated from the food supply during rinsing.

Good point about soil ecology.
Hugh Hellysetch - Fri, 02 Sep 2016 14:22:55 EST TtNn9wfR No.78206 Reply
Don't forget that companies like Monsanto are completely happy with the current GMO hate.

It just means that they have a monopoly position, because Monsanto can just set up an experimental farm in South-America and protect it with armed guards, while starting GMO companies have to do their experimental farms in the Western world and have fucking anti-GMO protesters (that may or may not be funded by Monsanto and other big companies) with bulldozers trashing their farms and send fucking bombs, bullet letters and mysterious powders to personnel and geneticists. Hell, people just doing research at universities without any profit gaining are getting death threats.
Shitting Messlepot - Sun, 04 Sep 2016 13:46:25 EST rybJ4K29 No.78220 Reply
1473011185994.jpg -(54663B / 53.38KB, 1170x1170) Thumbnail displayed, click image for full size.
but believe that pesticides don't wash off of food


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- Tue, 30 Aug 2016 00:39:47 EST zsw9I8fO No.78195
File: 1472531987880.jpg -(148371B / 144.89KB, 1280x1280) Thumbnail displayed, click image for full size. Chloroform
Wanna purify H.

Am I going to get watched (even moreso) if I order chloroform?
9 posts omitted. Click View Thread to read.
Bombastus !uYErosQbLM!!Mybq1UbK - Sat, 03 Sep 2016 17:42:58 EST Req4jw5M No.78218 Reply
Not true, if you wash the soxhlet before using it (and i mean really wash it), you can use it as a distillation apparatus if you pour out the solvent before it reaches the siphon tube.

It's ghetto as fuck but can work to save you $150 on a distillation condenser and adapter.
Ebenezer Soshgold - Sun, 04 Sep 2016 04:35:52 EST VjvGmScF No.78219 Reply
Probably just use DCM then, but the guides I were reading didn't mention it. Will just update whenever I attempt.
trypto - Tue, 06 Sep 2016 16:55:40 EST 6/EmvHqc No.78222 Reply
>you can use it as a distillation apparatus if you pour out the solvent before it reaches the siphon tube.

Haha. Hadn't thought of that.


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- Fri, 02 Sep 2016 15:26:59 EST CfiuryLA No.78207
File: 1472844419342.webm [mp4] -(3594835B / 3.43MB, 540x360) Thumbnail displayed, click image for full size. Classification
So this might be more semantic than scientific but I wanted your guys thoughts on the matter,

So hypothetically, if we did find life from another world, life evolved from a completely independent source than ours, and even if it was animate, easily recognizable life, maybe even humanoid...

It still couldn't technically be an animal or any of our kingdoms/domains of life, right? Like, when we're talking about the various domains and kingdoms of life, it's kind of implied those can only be terrestrial in origin since we're talking about a tree of life with a common ancestry right? Like if we got an Earth fungus to grow on another planet and it evolved into a new species of fungus to better live on that world, it would still be a fungus because it's ancestors were Earth fungi. But if a life form from somewhere in space from a completely different line of evolution were to travel to earth, even if it coincidentally shared a lot of similar traits to Earth fungi due to functional convergent evolution, it still could never be considered kingdom: fungi right?

tlIf do we sort alien life forms by phenotype traits or genotype ones?
Henry Brobberbitch - Fri, 02 Sep 2016 19:36:46 EST bvtI5MJW No.78210 Reply
i suspect that if and when we discover extraterrestrial life, biologists and zoologists will agree to classify every evolutionary ancestral lineage independently. maybe add a celestial identity marker, e.g. Terra Homo Sapiens Sapiens


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!/sly9iFJgg - Thu, 01 Sep 2016 08:07:03 EST H8Fdbu5S No.78201
File: 1472731623063.png -(165760B / 161.88KB, 640x1136) Thumbnail displayed, click image for full size. iNaturalist
It has some design flaws, like an inability to delete your own ID's, but it's hella fun and a great way to support the scientific community!

Estimating the relative potency of a fentanyl analogue

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- Mon, 15 Aug 2016 12:02:06 EST Y1ptdQKh No.78154
File: 1471276926041.png -(13693B / 13.37KB, 554x376) Thumbnail displayed, click image for full size. Estimating the relative potency of a fentanyl analogue
Dearest /chem/,

I wish I were one of you, but I'm not. My knowledge of chemistry trivia might impress at some parties but when actual questions arise, assistance is necessary. I was hoping you could help me estimate the relative potency of cyclopentyl-fentanyl, a novel fentanyl analogue. You will find It's structure displayed in the picture.

My thoughts: Cyclopentyl-F seems to be structurally related to Acryl-F. The latter is said to be active at doses <10 mcg. But on the other hand, cyclopentyl-F also seems related to Acetyl-F which is said to only be 1/20th the potency of regular fentanyl.

Thank you for your time.
Bombastus !RZEwn1AX62!!xXxJO70U - Thu, 25 Aug 2016 19:54:09 EST Req4jw5M No.78177 Reply
With most of this shit, you simply can't look at the molecule and guess its relative potency, unfortunately. This is just the reality of biological assays and why they are necessary.

Organic chemistry is simple to estimate but biochemistry requires in depth knowledge of all the enzyme sites around your receptors which can lead to potency changes. This is near impossible to do without high computational machines or more accurately: petri dish bio assays.

Sorry to burst your bubble, Sarringberk.
David Mondlelotch - Sun, 28 Aug 2016 11:12:00 EST wAPrdwU9 No.78185 Reply
Hi, a solution with 120-140mg / 10ml dest. water.
I recieved the powder in oxalate form, it needed alot of heating to solve. This solution was then added to a nasal spray. Akryl recipe, is 20mg/10ml dest water, for nasal sprays.


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- Tue, 23 Aug 2016 04:15:50 EST Ano5zrbo No.78164
File: 1471940150381.png -(1814256B / 1.73MB, 1920x1080) Thumbnail displayed, click image for full size. hydrogen
ik we are carbon based lifeforms but really, arent we hydrogen based life forms?
wouldnt all life be based off hydrogen in some fashion?
I mean look at it
H20 man.
8 posts and 2 images omitted. Click View Thread to read.
Caroline Crungermore - Sat, 27 Aug 2016 21:31:05 EST zsw9I8fO No.78182 Reply
I wasn't intending for this post to be taken seriously.
Bombastus !RZEwn1AX62!!xXxJO70U - Sun, 28 Aug 2016 02:14:08 EST Req4jw5M No.78183 Reply
1472364848352.jpg -(74184B / 72.45KB, 640x480) Thumbnail displayed, click image for full size.
Well you clearly underestimated my enthusiasm powers.

Books, books, more books

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!7HYGxe5v5c - Sun, 12 Jun 2016 22:36:55 EST zn1t5pEx No.77965
File: 1465785415158.png -(40799B / 39.84KB, 1189x269) Thumbnail displayed, click image for full size. Books, books, more books
Recently in the CWE thread someone was asking for book recommendations on chemistry textbooks, and the rest, and Press uploaded a couple of image-rars. I've been thinking we could benefit from our own central thread where we can discuss our collections, what we're reading, with an organic chemistry/synthesis theme. I know they have a good recommendation list at the /sci/ wiki over on 4chan, but fuck 4chan. This is /chem/ and we are a proud people. Also, we have a smaller community centered more around org-chem and synthesis, so it's a niche this thread should fill with more in-depth recommendations on the subject, and the provision of papers and other supplemental material.

To anyone looking for books, I'd recommend libgen. I only recently discovered it and I'm quite frankly relieved at not having to scour torrent sites and the awkward interface of #bookz for hours on end only to discover a rare book I'm looking for isn't being seeded.

I recently got Alan F Casy's Opioid Analgesics: Chemistry and Receptors off it, which I'd actually considering buying for about 50 euro used half a year ago. What a travesty that would have been. So far I've only checked out the chapter on 4-phenylpiperidines, but so far it's an interesting read. I used to have a better collection on my old computer but it crapped out, and here's what I'm working with at the moment while I rebuild it. I'm an undergrad, so I assume some of the more seasoned veterans here will have comprehensive collections.
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press !QUHukXEvkY - Mon, 27 Jun 2016 13:39:12 EST fcMijPsC No.78034 Reply

id guess that growing yeast or bacteria is a bit simpler and less dependant on sociopolitical bullshit than poppies.
Hamilton Honeylock - Wed, 03 Aug 2016 15:45:47 EST V/qMoGDW No.78127 Reply
Right, so what can you people tell me about them fume hoods? What do you have to consider when setting up a basement lab? I think I can't just go right ahead and pump all the fumes out the fucking window, right? Do I need some kind of filter? Are there any laws for this shit? It's really unfortunate for me because I can only do this in my basement with a window that's facing the backyard. Occasionally there are some fucking brats running around too. I beg for your help! It's the only thing seperating me from doing lab work

Why am I so fucking shit at kitchen chemistry

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!1CreRGKd/6!!TfPvomrn - Thu, 07 Jul 2016 21:22:03 EST 5Pw/LIPu No.78073
File: 1467940923077.jpg -(40715B / 39.76KB, 575x383) Thumbnail displayed, click image for full size. Why am I so fucking shit at kitchen chemistry
I fucking hate my life. Bombastus, can I please come live with you since you're actually good at chemistry? I promise I will be a faithful lab assistant, am totally willing to get a Canadian visa, and would love to learn all about how to not suck dick at kitchen chemistry.

I really need general tips on how to actually manage to perform kitchen chemistry and not fail at things as simple as fucking morphine extractions. Nothing I attempt ever seems to work. I'm just quite unhappy right now. Pls gib advice.

Sorry for the super low-res photo
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Bombastus !RZEwn1AX62!!xXxJO70U - Mon, 08 Aug 2016 14:46:39 EST HCt0W/hp No.78140 Reply
Good watch glasses and lab covers.
Liquid liquid extract everything else. Then filter extract morphine. That sounds easier than other options.

HCN my shit up fam.
Press - Tue, 09 Aug 2016 03:06:51 EST MKujOXWI No.78143 Reply
Meh, shits gonna get stuck at the rims.

Just methylmercury my fam, fuck
Bombastus !RZEwn1AX62!!xXxJO70U - Tue, 09 Aug 2016 19:42:54 EST HCt0W/hp No.78144 Reply
Methylmercury is probably a great way to suicide. It's like condensed cancer and the doctors would probably give you all the opiates you want. Maybe even some benzos.

pic related of my script

How water goes up straws

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- Sun, 07 Aug 2016 22:02:44 EST MVUX73Om No.78135
File: 1470621764791.gif -(1571571B / 1.50MB, 370x288) Thumbnail displayed, click image for full size. How water goes up straws
The reason that liquids go up straws is not because you're sucking it in but because you're displacing the oxygen inside the straw allowing the liquid to shape without the pressure of oxygen.
Bombastus !RZEwn1AX62!!xXxJO70U - Sun, 07 Aug 2016 23:32:27 EST HCt0W/hp No.78136 Reply
>displacing the oxygen
You mean the air? Specify. We're on /chem/ afteral
>allowing the liquid to shape
The definition of a liquid is that it has no shape nor does it retain on. what do you mean "the pressure of oxygen"?

Also, why did you start this thread even.
James Dinningbanks - Sun, 07 Aug 2016 23:59:23 EST MVUX73Om No.78137 Reply
I don't know, I like pretending like I know science
Bombastus !RZEwn1AX62!!xXxJO70U - Mon, 08 Aug 2016 14:47:21 EST HCt0W/hp No.78141 Reply
Good for you for admitting it, at least.


Oxymorphinol and Hydromorphinol

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!RZEwn1AX62!!xXxJO70U - Mon, 27 Jun 2016 02:29:51 EST G8mu3scS No.78032
File: 1467008991222.jpg -(92318B / 90.15KB, 790x753) Thumbnail displayed, click image for full size. Oxymorphinol and Hydromorphinol
Hey faggotqueers. Are these the same fucking thing?

Possible synthesis discussion below.
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Bombastus !RZEwn1AX62!!xXxJO70U - Fri, 22 Jul 2016 21:26:14 EST ycAJxrEI No.78108 Reply
I swear these shits are the same fucking thing.
Bombastus !RZEwn1AX62!!xXxJO70U - Sun, 24 Jul 2016 14:17:21 EST HCt0W/hp No.78111 Reply
No in the molecule. I still can't see the difference and it's NOT in chirality.

microscopic telescope

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- Fri, 22 Jul 2016 13:12:29 EST 6cilZam8 No.78106
File: 1469207549120.png -(11018B / 10.76KB, 798x294) Thumbnail displayed, click image for full size. microscopic telescope
I just wondered, I have never heard of a microscopic telescope. By this I mean a device along the lines of a large nature-style camera lens or traditional telecope that is able to zoom in to the target area of a physical item and produce a 3d environment of that area through the lens? Surely theres an infinite amount of detail from a physical item We have all this advanced astronomical technology these days to look at things that lie in the distance. What would happen if technology was put into microscopic telecopes thanks everyone

TLDR: a lens of intricately layered magnifying glasses that self multiply
Bombastus !RZEwn1AX62!!xXxJO70U - Fri, 22 Jul 2016 15:51:09 EST ElYFdcKO No.78107 Reply
the width of photons and their wave functions still have a measurement and you need to capture a lot of them to concentrate them. this is why a microscopic telescope isn't worth producing because they'd be so damn sensitive, there'd be no point. the curvature of the glass is also then limited due to the angles possible when the radius is limited.

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