Leave these fields empty (spam trap):
Name
You can leave this blank to post anonymously, or you can create a Tripcode by using the format Name#Password
Comment
[i]Italic Text[/i]
[b]Bold Text[/b]
[spoiler]Spoiler Text[/spoiler]
>Highlight/Quote Text
[pre]Preformatted & Monospace Text[/pre]
[super]Superset Text[/super]
[sub]Subset Text[/sub]
1. Numbered lists become ordered lists
* Bulleted lists become unordered lists
File

Sandwich


Discord Now Fully Linked With 420chan IRC

question regarding unusual substitutions

Reply
!57aon8jsJ2 - Fri, 27 Apr 2018 00:28:12 EST 7gSriUk/ No.79094
File: 1524803292499.jpg -(731734B / 714.58KB, 1836x3264) Thumbnail displayed, click image for full size. question regarding unusual substitutions
OK so /chem/ i purchased some drugs online but instead they sent me 98% para-hydroxy-cinnamic acid. what id like to know is can i use this despite only being 98% could i use this in the same way as people use acetic anhydride to add acetyl groups to open hydroxy positions specifically in opis at the 3,6,or 14 hydroxy positions? if not is it useful for really anything?

pic related the 25 grams of para-hydroxy-cinnamic acid
>>
Bombastus Werrywag - Sat, 12 May 2018 02:41:48 EST +BoDDLT6 No.79101 Reply
>>79094
Basic 1st year equilibrium reaction laws apply.

You have to make it into an anhydrous with SOCl. This is going to be like acetylation with Acetic Acid. It can't work because it'll generate AcOH before it makes Ac-Morph. that's why you have to make Acetic Anhydride first before doing any acetylation.
>>
bress - Sat, 12 May 2018 05:21:32 EST l33iXC6t No.79104 Reply
>>79101
wouldnt the carboxyl chloride then attack the phenolic functionality on the HO-cinnamic acid?
i reckon extremely low concentrations of the acylation agent compared to the substrate eg morphinnnnee would reduce the ammount of polymerizedd bullshit.
>>
Bombastus Werrywag - Mon, 14 May 2018 00:18:56 EST +BoDDLT6 No.79105 Reply
>>79104
excuse high and drunk facilitated retardation because i didn't read "para hydroxy" for some weird reason. just protect it using a benzoyl group or some sort of ether.

Report Post
Reason
Note
Please be descriptive with report notes,
this helps staff resolve issues quicker.