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The ketogenic diet increases adenosine - Caffeine related

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- Wed, 07 Aug 2019 22:46:00 EST NfYy/AS+ No.291859
File: 1565232360670.png -(2190667B / 2.09MB, 1271x861) Thumbnail displayed, click image for full size. The ketogenic diet increases adenosine - Caffeine related
This is an interesting read, keto seems to upregulate adenosine. Caffeine is an antagonist of adenosine receptors. So this suggests to me that keto would be particularly helpful for coffee drinkers/caffeine consumers. High intensity exercise also increases adenosine.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769009/
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Fucking Dopperbug - Thu, 19 Sep 2019 17:49:32 EST 9bHeOEEZ No.292394 Reply
>>291859
I'm more interested in whether it could recover on it's own back to baseline levels.
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Reuben Pittridge - Wed, 25 Sep 2019 04:34:46 EST lVbof4lL No.292439 Reply
1569400486844.jpg -(65753B / 64.21KB, 612x612) Thumbnail displayed, click image for full size.
So... keto & caffiene is a good combo?
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Emma Nimbleham - Fri, 27 Sep 2019 05:38:29 EST aBrn27uE No.292451 Reply
>>292439
I'm not sure what I was thinking when I made this thread, chronic caffeine usage upregulates adenosine too.
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Ernest Chuzzleman - Thu, 03 Oct 2019 04:30:48 EST o5xna3wX No.292493 Reply
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I want a boost
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John Shittingstock - Sat, 05 Oct 2019 23:47:31 EST OM8bi81d No.292524 Reply
What about keto and stims in general?
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Jesus Christ - Thu, 17 Oct 2019 11:10:43 EST 4Un9UPdU No.292656 Reply
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>>292655
if u fucking cut off your arm you could lose like 20 lbs my man

for me, I'd just have to cut off my dick, same thing
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Thomas Billingstock - Thu, 07 Nov 2019 20:43:40 EST fB0qHw9i No.292882 Reply
>>292524
This is very anecdotal, so take it with a grain of salt, but when I first switched to the keto diet (70% animal products for the first 2 months, and the rest was some nuts), I was drinking quite a bit of coffee - 6 espresso shots - and I remember that I felt like I only needed about 6 hours of sleep, which was very surprising to me, but what was REALLY startling was that when I woke up I was up like a ROCKET. I'd wake up and instantly be up, sometimes I'd literally jump out of bed. That effect didn't persist as I cut down on my caffeine intake.

Also I wonder if it'd help to cut down on caffeine intake by switching some coffee for dark chocolate or some other form of theobromine which is also a methylxanthine. It'd be like switching from one benzo to another while tapering off.
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CrazyFolksTribe !owU3wSU682 - Mon, 11 Nov 2019 04:20:03 EST fUjnEeN1 No.292907 Reply
Increase ≠ increased binding
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Martin Nonkinkurk - Tue, 12 Nov 2019 17:01:08 EST dkLh+K13 No.292915 Reply
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>>292656
is that caus you r balls r heavy cuz you dont have sex loll
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James Billingdock - Sun, 08 Dec 2019 09:38:02 EST +m2TUOm6 No.293167 Reply
>>292882
>when I woke up I was up like a ROCKET
I get this feeling on the keto diet without any caffeine lol
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Angus Hollerville - Wed, 01 Apr 2020 19:35:34 EST s+k1tOxt No.294286 Reply
>>291859
kind of unrelated but Ive been trying to kick my stim pill addiction w coffee
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Wesley Sumbleshit - Sat, 04 Apr 2020 10:48:21 EST s7zupMj+ No.294294 Reply
This is pretty off-topic, just popped into my head. If dopamine stimulating drugs such as Meth can down-regulate dopamine with heavy use, could drugs such as anti-psychotics that block dopamine(?) up-regulate it?
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Edwin Gimblechetch - Sat, 04 Apr 2020 11:24:10 EST o23pIvqG No.294295 Reply
>>294294
I suspect that CBD does this in large amounts (300mg+). Well at least in my experience it seems to.
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Henry Buncocke - Sat, 04 Apr 2020 11:34:29 EST nYUhNO+r No.294297 Reply
>>294295
CBD's anti psychotic effects have nothing to do with dopamine antagonism. It's hypothesized to have a novel mechanism by which this antipsychotic effect occurs, which is mediated through increased signaling in the mTOR pathway. This effect is being investigated as a new target for antipsychotic substances that have a significantly improved safety profile and more tolerable side-effects.
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Henry Buncocke - Sat, 04 Apr 2020 11:35:14 EST nYUhNO+r No.294298 Reply
>>294297
that would hopefully have an improved safety profile and less side-effects**
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Edwin Gimblechetch - Sat, 04 Apr 2020 11:44:00 EST o23pIvqG No.294299 Reply
>>294297
Well it seems to do something for me that ends up increasing the efficacy of my dexedrine
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Edwin Gimblechetch - Sat, 04 Apr 2020 13:54:10 EST o23pIvqG No.294300 Reply
>>294299
Maybe it has something to do with sleep? I’ve heard that CBD prolongs the most restorative phase of the sleep cycle
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Henry Buncocke - Sat, 04 Apr 2020 16:47:13 EST nYUhNO+r No.294301 Reply
could be any number of things, CBD isn;t very selective for any particular receptor, it causes a lot of downstream effects. It's effect as a 5-HT1A partial agonist is probably one of the more likely candidates for how its helping you out. 5-HT1A agonists and partial agonists are known to cause a mood lift and reduce anxiety

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