|>> || >>292536 |
Be careful of assuming correlation is causation, particularly when you're taking multiple extremely, extremely powerful psychoactive drugs. This could have easily been "caused" by the previous klonopin done wearing off and the subsequent rebound anxiety all benzos cause. Other than that, it was most likely caused by placebo, especially if you've never tried plugging amph before.
While plugging amph has a shorter onset of action compared to oral use, the bioavailability is nearly the same. Oral amph BA is supposedly ~75-100%, and assuming rectal BA is say ~95% or less, say ~90%, that's only a maximum of 20% increase in BA, at the cost of potential powder residue loss, addy-filled liquid loss, and your bowels not being completely empty. IMO, over time, plugging rectal amph on a daily basis likely is a net loss in effective BA due to these reasons.
It's also possible that at least one of the two amph salts in adderall that are 50/50 d-amph and l-amph have a higher BA increase when consumed rectally than the relative BA increase for the two amph salts that are 100% d-amph. This would result in increased negatve side effects compared to when taken orally.
If you can, I HIGHLY suggest convincing your doctor to switch you to ~60mg dexedrine. Even if they're overly informed and insist that you switch to only 45mg dexedrine because it's pretty much equal to 60mg Adderall (though I'd argue that l-amph is roughly 25% as potent mg for mg as d-amph, meaning that dexedrine would arguably be only ~24.75% stronger than adderall mg for mg, instead of the often assumed 33.33% stronger)./[%]
Not only will you be able to effectively boost your daily script from 60mg to 80mg addy, it's important to know that dexedrine has a LOT less negative side effects compared to adderall, ESPECIALLY at doses arguably above ~30-40mg per day. The only problems with dexedrine are that it's way to expensive without insurance, the highest dose tablets that are made are only 10mg for IR and 15mg for XR, and they're often harder for your pharmacy to source than adderall. That's why I typically have my doctor script me ~2-3 months of dexedrine at once. Otherwise I'd be waiting ~7-20 days for just 30 days worth of meds every month.
I can't wait for my new dex script to be filled. I'm so tired of adderall's bullshit physical norepinephrine-related side effects. Even if pure dexedrine has less physical "push" than adderall, that can easily be solved by taking a smaller portion of adderall instead of your amph dose being entirely adderall. For example, instead of taking say 60mg of adderall (which contains ~15mg of levo-amph), you could take say 40-45mg of dexedrine with 15-20mg adderall. That way, you do get a minimal amount of levo-amph so you're up and moving instead of jerking off or gaming all the time, but it's only ~5mg l-amph or less. This means less high blood pressure, less anxiety, slightly slower heart rate (assuming you're taking the same amount of d-amph as before, so you're not just taking 60mg dexedrine instead of 60mg adderall), and most of all LESS INSOMNIA (l-amph has a half-life that's like ~1-2.5hr longer than d-amph, so when you crash it's mostly just l-amph in your system...hence the irritability).
I am also scripted 60mg adderall, but for the first time in over a year of being scripted this stuff, I had a binge pseudo-addiction problem of taking more than prescribed because my doctor fucked up the script and wrote me over 1 month extra in quantity. As I need to taper in order to not run out before the new script is filled, I've tapered down from as much as fucking ~90-200mg+ per day to "just" ~52.5mg today. Every day I drop by 7.5mg, and intend to get down to 37.5mg minimum, hopefully 30mg.
Not to be too arbitrary, but chances are that more than 30mg adderall or 22.5-25mg dexedrine per day just plain isn't good for your body whatsoever, especially if it's IR taken all at once. Besides, I'm sure you've realized that using doses as high as ~60-90mg/day, or especially over 100mg/day, makes the dopamine/"high" part of amph go away almost entirely, while a large portion of the norepinephrine-related "push," that causes anxiety/insomnia/excessive BP/HR increase, and other problems at higher doses, seems to remain.
Definitely consider trying to taper down, or at least dose lower on days you likely won't "need" adderall's effects as much. Daily dosing high levels of amph without magnesium, various NMDA antagonists, and other helpful supplements is bad news eventually. It's "only" been maybe ~15 months since I started on adderall (originally like ~20-30mg I think, off and on switching between dexedrine and addy depending on insurance, but eventually got it boosted to 60mg/day maybe ~6 months ago).